Strong mechanically-induced effects in DC current-biased suspended Josephson junctions

Superconductivity is a result of quantum coherence at macroscopic scales. Two superconductors separated by a metallic or insulating weak link exhibit the AC Josephson effect - the conversion of a DC voltage bias into an AC supercurrent. This current may be used to activate mechanical oscillations in a suspended weak link. As the DC voltage bias condition is remarkably difficult to achieve in experiments, here we analyse theoretically how the Josephson effect can be exploited to activate and detect mechanical oscillations in the experimentally relevant condition with purely DC current bias. We unveil for the first time how changing the strength of the electromechanical coupling results in two qualitatively different regimes showing dramatic effects of the oscillations on the DC current-voltage characteristic of the device. These include the apperance of Shapiro-like plateaux for weak coupling and a sudden mechanically-induced retrapping for strong coupling. Our predictions, measurable in state of the art experimental setups, allow the determination of the frequency and quality factor of the resonator using DC only techniques.Comment: 10 pages, 6 figure

Level Set Dynamics and the Non-blowup of the 2D Quasi-geostrophic Equation

In this article we apply the technique proposed in Deng-Hou-Yu (Comm. PDE, 2005) to study the level set dynamics of the 2D quasi-geostrophic equation. Under certain assumptions on the local geometric regularity of the level sets of $\theta$, we obtain global regularity results with improved growth estimate on $| \nabla^{\bot} \theta |$. We further perform numerical simulations to study the local geometric properties of the level sets near the region of maximum $| \nabla^{\bot} \theta |$. The numerical results indicate that the assumptions on the local geometric regularity of the level sets of $\theta$ in our theorems are satisfied. Therefore these theorems provide a good explanation of the double exponential growth of $| \nabla^{\bot} \theta |$ observed in this and past numerical simulations.Comment: 25 pages, 10 figures. Corrected a few typo

Land Rights Insecurity and Temporary Migration in Rural China

Like most other developing countries, China experiences huge migration outflows from rural areas. Their most striking characteristic is a high geographical and temporal mobility. Rural migrants keep going back and forth between origin villages and destination areas. In this paper, we show that this temporary feature of migration can be linked to land rights insecurity. As village land ownership remains collective and as land use rights can be periodically reallocated, individual out-migration can result in deprivation of those rights. Moreover, the intensity of this insecurity varies according to the village-level management of land and the contractual status of land plots. We use these variations to identify the effect of land rights insecurity on migration behavior. Empirical results based on representative 2002 rural data demonstrate substantial impact.migration, land rights insecurity, China, semiparametric censored regression models

Evidence for Solar Tether-cutting Magnetic Reconnection from Coronal Field Extrapolations

Magnetic reconnection is one of the primary mechanisms for triggering solar eruptive events, but direct observation of its rapid process has been of challenge. In this Letter we present, using a nonlinear force-free field (NLFFF) extrapolation technique, a visualization of field line connectivity changes resulting from tether-cutting reconnection over about 30 minutes during the 2011 February 13 M6.6 flare in NOAA AR 11158. Evidence for the tether-cutting reconnection was first collected through multiwavelength observations and then by the analysis of the field lines traced from positions of four conspicuous flare 1700 A footpoints observed at the event onset. Right before the flare, the four footpoints are located very close to the regions of local maxima of magnetic twist index. Especially, the field lines from the inner two footpoints form two strongly twisted flux bundles (up to ~1.2 turns), which shear past each other and reach out close to the outer two footpoints, respectively. Immediately after the flare, the twist index of regions around the footpoints greatly diminish and the above field lines become low lying and less twisted (~0.6 turns), overarched by loops linking the later formed two flare ribbons. About 10% of the flux (~3x10^19 Mx) from the inner footpoints has undergone a footpoint exchange. This portion of flux originates from the edge regions of the inner footpoints that are brightened first. These rapid changes of magnetic field connectivity inferred from the NLFFF extrapolation are consistent with the tether-cutting magnetic reconnection model.Comment: 6 pages, 5 figures, accepted to the Astrophysical Journal Letter

High-fidelity gene targeting in embryonic stem cells by using sequence replacement vectors.

Journal ArticleMutations were targeted to the Hprt locus in murine embryonic stem cells by using sequence replacement vectors. When the vector was designed such that the mutated sequences were flanked on both sides by several kilobases of DNA homologous to the target locus, replacement of chromosomal sequences with the exogenous DNA occurred with precision. If, on the other hand, the target-homologous DNA on one arm of the vector was reduced to below 1 kb in length, the fidelity of recombination was diminished

Location of crossovers during gene targeting with insertion and replacement vectors.

Journal ArticleGene targeting was used to introduce nonselectable genetic changes into chromosomal loci in mouse embryo-derived stem cells. The nonselectable markers were linked to a selectable marker in both insertion- and replacement-type vectors, and the transfer of the two elements to the Hprt locus was assayed. When insertion vectors were used as substrates, the frequency of transfer was highly dependent upon the distance between the nonselectable marker and the double-strand break in the vector. A marker located close to the vector ends was frequently lost, suggesting that a double-strand gap repair activity is involved in vector integration. When replacement vectors were used, cotransfer of a selectable marker and a nonselectable marker 3 kb apart was over 50%, suggesting that recombination between vector and target often occurs near the ends of the vector. To illustrate the use of replacement vectors to transfer specific mutations to the genome, we describe targeting of the delta F508 mutation to the CFTR gene in mouse embryo-derived stem cells

Balancing Exploration and Exploitation: A New Algorithm for Active Machine Learning

Active machine learning algorithms are used when large numbers of unlabeled examples are available and getting labels for them is costly (e.g. requiring consulting a human expert). Many conventional active learning algorithms focus on refining the decision boundary, at the expense of exploring new regions that the current hypothesis misclassifies. We propose a new active learning algorithm that balances such exploration with refining of the decision boundary by dynamically adjusting the probability to explore at each step. Our experimental results demonstrate improved performance on data sets that require extensive exploration while remaining competitive on data sets that do not. Our algorithm also shows significant tolerance of noise

Blending poly(butylene succinate) with poly(lactic acid): ductility and phase inversion effects

Synergistic effects of blending two bio-based, bio-degradable polymers, poly(butylene succinate) (PBS) and poly(lactic acid) (PLA) are investigated. A series of melt-blended compounds were prepared at PBS/PLA weight ratios of 0/100, 10/90, 20/80, 40/60, 60/40, 80/20 and 100/0. Thermal properties, crystallinity, melt viscosities, mechanical properties and phase morphology were studied. There was found to be a dramatic improvement in ductility, over 250% elongation-to-break, with as little as 10 wt% of PBS added. This was shown to be due to a co-continuous phase morphology, which was determined by the relative viscosities of the components