Quantum Einstein-Dirac Bianchi Universes

We study the mini--superspace quantization of spatially homogeneous (Bianchi) cosmological universes sourced by a Dirac spinor field. The quantization of the homogeneous spinor leads to a finite-dimensional fermionic Hilbert space and thereby to a multi-component Wheeler-DeWitt equation whose main features are: (i) the presence of spin-dependent Morse-type potentials, and (ii) the appearance of a q-number squared-mass term, which is of order ${\cal O}(\hbar^2)$, and which is affected by ordering ambiguities. We give the exact quantum solution of the Bianchi type-II system (which contains both scattering states and bound states), and discuss the main qualitative features of the quantum dynamics of the (classically chaotic) Bianchi type-IX system. We compare the exact quantum dynamics of fermionic cosmological billiards to previous works that described the spinor field as being either classical or Grassmann-valued.Comment: 50 page

Tradeoffs in Community Properties Through Time in a Desert Rodent Community

Resource limitation represents an important constraint on ecological communities, which restricts the total abundance, biomass, and community energy flux a given community can support. However, the exact relationship among these three measures of biological activity remains unclear. Here we use a simple framework that links abundance and biomass with an energetic constraint. Under constant energetic availability, it is expected that changes in abundance and biomass can result from shifts in the distribution of individual masses. We test these predictions using long-term data from a desert rodent community. Total energy use for the community has not changed directionally for 25 years, but species composition has. As a result, the average body size has decreased by almost 50% and average abundance has doubled. These results lend support to the idea of resource limitation on desert rodent communities and demonstrate that systems are able to maintain community energy flux in the face of environmental change, through changes in composition and structure

Photon rockets and gravitational radiation

The absence of gravitational radiation in Kinnersley's ``photon rocket'' solution of Einstein's equations is clarified by studying the mathematically well-defined problem of point-like photon rockets in Minkowski space (i.e. massive particles emitting null fluid anisotro\-pically and accelerating because of the recoil). We explicitly compute the (uniquely defined) {\it linearized} retarded gravitational waves emitted by such objects, which are the coherent superposition of the gravitational waves generated by the motion of the massive point-like rocket and of those generated by the energy-momentum distribution of the photon fluid. In the special case (corresponding to Kinnersley's solution) where the anisotropy of the photon emission is purely dipolar we find that the gravitational wave amplitude generated by the energy-momentum of the photons exactly cancels the usual $1/r$ gravitational wave amplitude generated by the accelerated motion of the rocket. More general photon anisotropies would, however, generate genuine gravitational radiation at infinity. Our explicit calculations show the compatibility between the non-radiative character of Kinnersley's solution and the currently used gravitational wave generation formalisms based on post-Minkowskian perturbation theory.Comment: 21 pages, LATEX, submitted to Class. Quant. Gra

A Delphi study to strengthen research methods training in undergraduate psychology programmes

Psychology programmes often emphasise inferential statistical tests over a solid understanding of data and research design. This imbalance may leave graduates under-equipped to effectively interpret research and employ data to answer questions. We conducted a two-round modified-Delphi to identify the research methods skills that the UK psychology community deems essential for undergraduates to learn. Participants included 103 research methods instructors, academics, students, and non-academic psychologists. Of 78 items included in the consensus process, 34 reached consensus. We coupled these results with a qualitative analysis of 707 open-ended text responses to develop nine recommendations for organisations that accredit undergraduate psychology programmes—such as the British Psychological Society (BPS). We recommend that accreditation standards emphasise (1) dataskills, (2) research design, (3) descriptive statistics, (4) critical analysis, (5) qualitative methods, and (6) both parameter estimation and significance testing; as well as (7) give precedence to foundational skills, (8) promote transferable skills, and (9) create space in curricula to enable these recommendations. Our data and findings can inform modernised accreditation standards to include clearly-defined, assessable, and widely-encouraged skills that foster a competent graduate body for the contemporary world

Production Of Dna Minicircles Less Than 250 Base Pairs Through A Novel Concentrated Dna Circularization Assay Enabling Minicircle Design With Nf-κb Inhibition Activity

Double-stranded DNA minicircles of less than 1000 bp in length have great interest in both fundamental research and therapeutic applications. Although minicircles have shown promising activity in gene therapy thanks to their good biostability and better intracellular trafficking, minicircles down to 250 bp in size have not yet been investigated from the test tube to the cell for lack of an efficient production method. Herein, we report a novel versatile plasmidfree method for the production of DNA minicircles comprising fewer than 250 bp. We designed a linear nicked DNA double-stranded oligonucleotide bluntended substrate for efficient minicircle production in a ligase-mediated and bending protein-assisted circularization reaction at high DNA concentration of 2M. This one pot multi-step reaction based-method yields hundreds of micrograms of minicircle with sequences of any base composition and position and containing or not a variety of site-specifically chemical modifications or physiological supercoiling. Biochemical and cellular studies were then conducted to design a 95 bp minicircle capable of binding in vitro two NF-κB transcription factors per minicircle and to efficiently inhibiting NF-κB-dependent transcriptional activity in human cells. Therefore, our production method could pave the way for the design of minicircles as new decoy nucleic acids. © The Author(s) 2016.45

Testing the equivalence principle: why and how?

Part of the theoretical motivation for improving the present level of testing of the equivalence principle is reviewed. The general rationale for optimizing the choice of pairs of materials to be tested is presented. One introduces a simplified rationale based on a trichotomy of competing classes of theoretical models.Comment: 11 pages, Latex, uses ioplppt.sty, submitted to Class. Quantum Gra

Investigation of wall normal electromagnetic actuator for seawater flow control

Submitted versio

Describing general cosmological singularities in Iwasawa variables

Belinskii, Khalatnikov, and Lifshitz (BKL) conjectured that the description of the asymptotic behavior of a generic solution of Einstein equations near a spacelike singularity could be drastically simplified by considering that the time derivatives of the metric asymptotically dominate (except at a sequence of instants, in the `chaotic case') over the spatial derivatives. We present a precise formulation of the BKL conjecture (in the chaotic case) that consists of basically three elements: (i) we parametrize the spatial metric $g_{ij}$ by means of \it{Iwasawa variables} $\beta^a, {\cal N}^a{}_i$); (ii) we define, at each spatial point, a (chaotic) \it{asymptotic evolution system} made of ordinary differential equations for the Iwasawa variables; and (iii) we characterize the exact Einstein solutions $\beta, {\cal{N}}$ whose asymptotic behavior is described by a solution $\beta_{[0]}, {\cal N}_{[0]}$ of the previous evolution system by means of a `\it{generalized Fuchsian system}' for the differenced variables $\bar \beta = \beta - \beta_{[0]}$, $\bar {\cal N} = {\cal N} - {\cal N}_{[0]}$, and by requiring that $\bar \beta$ and $\bar {\cal N}$ tend to zero on the singularity. We also show that, in spite of the apparently chaotic infinite succession of `Kasner epochs' near the singularity, there exists a well-defined \it{asymptotic geometrical structure} on the singularity : it is described by a \it{partially framed flag}. Our treatment encompasses Einstein-matter systems (comprising scalar and p-forms), and also shows how the use of Iwasawa variables can simplify the usual (`asymptotically velocity term dominated') description of non-chaotic systems.Comment: 50 pages, 4 figure

Multi-slice ptychographic tomography

Ptychography is a form of Coherent Diffractive Imaging, where diffraction patterns are processed by iterative algorithms to recover an image of a specimen. Although mostly applied in two dimensions, ptychography can be extended to produce three dimensional images in two ways: via multi-slice ptychography or ptychographic tomography. Ptychographic tomography relies on 2D ptychography to supply projections to conventional tomographic algorithms, whilst multi-slice ptychography uses the redundancy in ptychographic data to split the reconstruction into a series of axial slices. Whilst multi-slice ptychography can handle multiple-scattering thick specimens and has a much smaller data requirement than ptychographic tomography, its depth resolution is relatively poor. Here we propose an imaging modality that combines the benefits of the two approaches, enabling isotropic 3D resolution imaging of thick specimens with a small number of angular measurements. Optical experiments validate our proposed method