Support for smoke-free multi-unit housing policies among racially and ethnically diverse, low-income seniors in south florida

Open access: http://link.springer.com/article/10.1007/s10823-014-9247-4/fulltext.html Previous studies have gauged support for implementing smoke-free MUH policies in the United States, but none have specifically examined attitudes among racially and ethnically diverse seniors living in low-income MUH. As part of an evaluation of a Community Transformation Grant funded program, we surveyed senior residents 62 years of age and older (n = 807) in 24 low-income housing properties in Broward County, Florida, to assess residents’ smoking behaviors, exposure to SHS, and support for smoke-free MUH policies. The study sample was ethnically and racially diverse with Hispanics comprising more than 61% of the population, and 22% of the population identified as Black or other races. Although close to 22% of the sample were former smokers, only 9% of residents reported being current smokers. The majority of residents surveyed supported no-smoking policies: 75% support no-smoking policies for individual units; 77% supported no-smoking policies in common areas; and, 68% supported no-smoking policies in outdoor areas. Over 29% of residents surveyed reported being exposed to secondhand smoke entering their units from elsewhere in their building. In sub-group analysis, Hispanic residents were significantly more likely to support both indoor (84.3 vs. 76.5, p\u3c.05) and outdoor (80.0 vs. 67.4, p\u3c.01) policies compared to non-Hispanic residents. Support for smoke-free policies did not vary significantly by race. This study demonstrates that senior residents living in low-income MUH properties overwhelmingly supported the implementation of smoke-free policies

Clinical Outcomes of Intraoperative Radiation Therapy for Extremity Sarcomas

Purpose. Radiation of extremity lesions, a key component of limb-sparing therapy, presents particular challenges, with significant risks of toxicities. We sought to explore the efficacy of intraoperative radiation therapy (IORT) in the treatment of soft tissue sarcomas of the extremities. Patients. Between 1995 and 2001, 17 patients received IORT for soft tissue sarcomas of the extremities. Indications for IORT included recurrent tumors in a previously radiated field or tumors adjacent to critical structures. Results. Gross total resections were achieved in all 17 patients. Two patients experienced locoregional relapses, six patients recurred at metastatic sites, and one patient died without recurrence. Thirty-six month estimates for locoregional control, disease free survival, and overall survival were 86%, 50%, and 78%, respectively. IORT was extremely well tolerated, with no toxicities referable to IORT. Conclusions. For patients with soft tissue sarcomas of the extremities, IORT used as a boost to EBRT provides excellent local control, with limited acute toxicities

Atomic Resonance and Scattering

Contains reports on nine research projects.U.S. Energy Research and Development Administration (Contract EG-77-S-02-4370)U. S. Air Force - Office of Scientific Research (Contract F44620-72-C-0057)Joint Services Electronics Program (Contract DAAB07-76-C-1400)National Science Foundation (Grant PHY75-15421-AO1)National Science Foundation (Grant PHY77-09155)National Science Foundation (Grant CHE76-81750)U. S. Air Force - Office of Scientific Research (Grant AFOSR-76-2972A

Atomic Resonance and Scattering

Contains reports on eight research projects.National Science Foundation (Grant PHY77-09155)Joint Services Electronics Program (Contract DAAG29-78-C-0020)U. S. Department of Energy (Grant EG-77-S-02-4370)National Science Foundation (Grant DMR 77-10084)National Aeronautics and Space Administration (Grant NSG-1551)U. S. Air Force - Office of Scientific Research (Grant AFOSR-76-2972)National Science Foundation (Grant CHE76-81750

MicroRNA miR-34 Inhibits Human Pancreatic Cancer Tumor-Initiating Cells

Our results demonstrate that miR-34 may restore, at least in part, the tumor suppressing function of the p53 in p53-deficient human pancreatic cancer cells. Our data support the view that miR-34 may be involved in pancreatic cancer stem cell self-renewal, potentially via the direct modulation of downstream targets Bcl-2 and Notch, implying that miR-34 may play an important role in pancreatic cancer stem cell self-renewal and/or cell fate determination. Restoration of miR-34 may hold significant promise as a novel molecular therapy for human pancreatic cancer with loss of p53-miR34, potentially via inhibiting pancreatic cancer stem cells