The KATRIN Experiment

The KArlsruhe TRitium Neutrino mass experiment, KATRIN, aims to search for the mass of the electron neutrino with a sensitivity of 0.2 eV/c^2 (90% C.L.) and a detection limit of 0.35 eV/c^2 (5 sigma). Both a positive or a negative result will have far reaching implications for cosmology and the standard model of particle physics and will give new input for astroparticle physics and cosmology. The major components of KATRIN are being set up at the Karlsruhe Institut of Technology in Karlsruhe, Germany, and test measurements of the individual components have started. Data taking with tritium is scheduled to start in 2012.Comment: 3 pages, 1 figure, proceedings of the TAUP 2009 International Conference on Topics in Astroparticle and Underground Physics, to be published in Journal of Physics, Conference Serie

Monitoring of tritium purity during long-term circulation in the KATRIN test experiment LOOPINO using laser Raman spectroscopy

The gas circulation loop LOOPINO has been set up and commissioned at Tritium Laboratory Karlsruhe (TLK) to perform Raman measurements of circulating tritium mixtures under conditions similar to the inner loop system of the neutrino-mass experiment KATRIN, which is currently under construction. A custom-made interface is used to connect the tritium containing measurement cell, located inside a glove box, with the Raman setup standing on the outside. A tritium sample (purity > 95%, 20 kPa total pressure) was circulated in LOOPINO for more than three weeks with a total throughput of 770 g of tritium. Compositional changes in the sample and the formation of tritiated and deuterated methanes CT_(4-n)X_n (X=H,D; n=0,1) were observed. Both effects are caused by hydrogen isotope exchange reactions and gas-wall interactions, due to tritium {\beta} decay. A precision of 0.1% was achieved for the monitoring of the T_2 Q_1-branch, which fulfills the requirements for the KATRIN experiment and demonstrates the feasibility of high-precision Raman measurements with tritium inside a glove box

Theory of neutrinoless double beta decay

Neutrinoless double beta decay, which is a very old and yet elusive process, is reviewed. Its observation will signal that lepton number is not conserved and the neutrinos are Majorana particles. More importantly it is our best hope for determining the absolute neutrino mass scale at the level of a few tens of meV. To achieve the last goal certain hurdles have to be overcome involving particle, nuclear and experimental physics. Nuclear physics is important for extracting the useful information from the data. One must accurately evaluate the relevant nuclear matrix elements, a formidable task. To this end, we review the sophisticated nuclear structure approaches recently been developed, which give confidence that the needed nuclear matrix elements can be reliably calculated. From an experimental point of view it is challenging, since the life times are long and one has to fight against formidable backgrounds. If a signal is found, it will be a tremendous accomplishment. Then, of course, the real task is going to be the extraction of the neutrino mass from the observations. This is not trivial, since current particle models predict the presence of many mechanisms other than the neutrino mass, which may contribute or even dominate this process. We will, in particular, consider the following processes: (i)The neutrino induced, but neutrino mass independent contribution. (ii)Heavy left and/or right handed neutrino mass contributions. (iii)Intermediate scalars (doubly charged etc). (iv)Supersymmetric (SUSY) contributions. We will show that it is possible to disentangle the various mechanisms and unambiguously extract the important neutrino mass scale, if all the signatures of the reaction are searched in a sufficient number of nuclear isotopes.Comment: 104 pages, 6 tables, 25 figures.References added. To appear in ROP (Reports on Progress in Physics), copyright RO

Revisiting Bimaximal Neutrino Mixing in a Model with S4 Discrete Symmetry

In view of the fact that the data on neutrino mixing are still compatible with a situation where Bimaximal mixing is valid in first approximation and it is then corrected by terms of order of the Cabibbo angle, arising from the diagonalization of the charged lepton masses, we construct a model based on the discrete group S4 where those properties are naturally realized. The model is supersymmetric in 4-dimensions and the complete flavour group is S4 x Z4 x U(1)_FN, which also allows to reproduce the hierarchy of the charged lepton spectrum. The only fine tuning needed in the model is to reproduce the small observed value of r, the ratio between the neutrino mass squared differences. Once the relevant parameters are set to accommodate r then the spectrum of light neutrinos shows a moderate normal hierarchy and is compatible, within large ambiguities, with the constraints from leptogenesis as an explanation of the baryon asymmetry in the Universe.Comment: 30 pages, 5 figures; added reference

A UV LED-based fast-pulsed photoelectron source for time-of-flight studies

We report on spectroscopy and time-of-flight measurements using an 18 keV fast-pulsed photoelectron source of adjustable intensity, ranging from single photoelectrons per pulse to 5 photoelectrons per microsecond at pulse repetition rates of up to 10 kHz. Short pulses between 40 ns and 40 microseconds in length were produced by switching light emitting diodes with central output wavelengths of 265 nm and 257 nm, in the deep ultraviolet (or UV-C) regime, at kHz frequencies. Such photoelectron sources can be useful calibration devices for testing the properties of high-resolution electrostatic spectrometers, like the ones used in current neutrino mass searches.Comment: 16 pages, 11 figure

Persistent neuropsychiatric symptoms after COVID-19: a systematic review and meta-analysis.

The nature and extent of persistent neuropsychiatric symptoms after COVID-19 are not established. To help inform mental health service planning in the pandemic recovery phase, we systematically determined the prevalence of neuropsychiatric symptoms in survivors of COVID-19. For this pre-registered systematic review and meta-analysis (PROSPERO ID CRD42021239750), we searched MEDLINE, EMBASE, CINAHL and PsycINFO to 20 February 2021, plus our own curated database. We included peer-reviewed studies reporting neuropsychiatric symptoms at post-acute or later time-points after COVID-19 infection and in control groups where available. For each study, a minimum of two authors extracted summary data. For each symptom, we calculated a pooled prevalence using generalized linear mixed models. Heterogeneity was measured with I 2. Subgroup analyses were conducted for COVID-19 hospitalization, severity and duration of follow-up. From 2844 unique titles, we included 51 studies (n = 18 917 patients). The mean duration of follow-up after COVID-19 was 77 days (range 14-182 days). Study quality was most commonly moderate. The most prevalent neuropsychiatric symptom was sleep disturbance [pooled prevalence = 27.4% (95% confidence interval 21.4-34.4%)], followed by fatigue [24.4% (17.5-32.9%)], objective cognitive impairment [20.2% (10.3-35.7%)], anxiety [19.1% (13.3-26.8%)] and post-traumatic stress [15.7% (9.9-24.1%)]. Only two studies reported symptoms in control groups, both reporting higher frequencies in COVID-19 survivors versus controls. Between-study heterogeneity was high (I 2 = 79.6-98.6%). There was little or no evidence of differential symptom prevalence based on hospitalization status, severity or follow-up duration. Neuropsychiatric symptoms are common and persistent after recovery from COVID-19. The literature on longer-term consequences is still maturing but indicates a particularly high prevalence of insomnia, fatigue, cognitive impairment and anxiety disorders in the first 6 months after infection

Topical Review on "Beta-beams"

Neutrino physics is traversing an exciting period, after the important discovery that neutrinos are massive particles, that has implications from high-energy physics to cosmology. A new method for the production of intense and pure neutrino beams has been proposed recently: the ``beta-beam''. It exploits boosted radioactive ions decaying through beta-decay. This novel concept has been the starting point for a new possible future facility. Its main goal is to address the crucial issue of the existence of CP violation in the lepton sector. Here we review the status and the recent developments with beta-beams. We discuss the original, the medium and high-energy scenarios as well as mono-chromatic neutrino beams produced through ion electron-capture. The issue of the degeneracies is mentioned. An overview of low energy beta-beams is also presented. These beams can be used to perform experiments of interest for nuclear structure, for the study of fundamental interactions and for nuclear astrophysics.Comment: Topical Review for Journal of Physics G: Nuclear and Particle Physics, published version, minor corrections, references adde

Viscerotropic disease: case definition and guidelines for collection, analysis, and presentation of immunization safety data

Viscerotropic disease (VTD) is defined as acute multiple organ system dysfunction that occurs following vaccination. The severity of VTD ranges from relatively mild multisystem disease to severe multiple organ system failure and death. The term VTD was first used shortly after the initial published reports in 2001 of febrile multiple organ system failure following yellow fever (YF) vaccination. To date, VTD has been reported only in association with YF vaccine and has been thus referred to as YF vaccine-associated viscerotropic disease (YEL-AVD)

Measurement of the cosmic ray spectrum above 4×10184{\times}10^{18} eV using inclined events detected with the Pierre Auger Observatory

A measurement of the cosmic-ray spectrum for energies exceeding $4{\times}10^{18}$ eV is presented, which is based on the analysis of showers with zenith angles greater than $60^{\circ}$ detected with the Pierre Auger Observatory between 1 January 2004 and 31 December 2013. The measured spectrum confirms a flux suppression at the highest energies. Above $5.3{\times}10^{18}$ eV, the "ankle", the flux can be described by a power law $E^{-\gamma}$ with index $\gamma=2.70 \pm 0.02 \,\text{(stat)} \pm 0.1\,\text{(sys)}$ followed by a smooth suppression region. For the energy ($E_\text{s}$) at which the spectral flux has fallen to one-half of its extrapolated value in the absence of suppression, we find $E_\text{s}=(5.12\pm0.25\,\text{(stat)}^{+1.0}_{-1.2}\,\text{(sys)}){\times}10^{19}$ eV.Comment: Replaced with published version. Added journal reference and DO