Interannual Variability in Dry Mixed-Grass Prairie Yield: A Comparison of MODIS, SPOT, and Field Measurements

Remote sensing is often used to assess rangeland condition and biophysical parameters across large areas. In particular, the relationship between the Normalized Difference Vegetation Index (NDVI) and above-ground biomass can be used to assess rangeland primary productivity (seasonal carbon gain or above-ground biomass “yield”). We evaluated the NDVI–yield relationship for a southern Alberta prairie rangeland, using seasonal trends in NDVI and biomass during the 2009 and 2010 growing seasons, two years with contrasting rainfall regimes. The study compared harvested biomass and NDVI from field spectrometry to NDVI from three satellite platforms: the Aqua and Terra Moderate Resolution Imaging Spectroradiometer (MODIS) and Système Pour l’Observation de la Terre (SPOT 4 and 5). Correlations between ground spectrometry and harvested biomass were also examined for each growing season. The contrasting precipitation patterns were easily captured with satellite NDVI, field NDVI and green biomass measurements. NDVI provided a proxy measure for green plant biomass, and was linearly related to the log of standing green biomass. NDVI phenology clearly detected the green biomass increase at the beginning of each growing season and the subsequent decrease in green biomass at the end of each growing season due to senescence. NDVI–biomass regressions evolved over each growing season due to end-of-season senescence and carryover of dead biomass to the following year. Consequently, mid-summer measurements yielded the strongest correlation (R2 = 0.97) between NDVI and green biomass, particularly when the data were spatially aggregated to better match the satellite sampling scale. Of the three satellite platforms (MODIS Aqua, MODIS Terra, and SPOT), Terra yielded the best agreement with ground-measured NDVI, and SPOT yielded the weakest relationship. When used properly, NDVI from satellite remote sensing can accurately estimate peak-season productivity and detect interannual variation in standing green biomass, and field spectrometry can provide useful validation for satellite data in a biomass monitoring program in this prairie ecosystem. Together, these methods can be used to identify the effects of year-to-year precipitation variability on above-ground biomass in a dry mixed-grass prairie. These findings have clear applications in monitoring yield and productivity, and could be used to support a rangeland carbon monitoring program

Opioid-Related Visits to Rural Emergency Departments

Increased rates of acute opioid poisoning and related emergency department (ED) visits in the United States have occurred at the same time as rural EDs face a number of resource constraints. Researchers at the Maine Rural Health Research Center conducted this study to gain insight about rural ED visits for acute opioid poisoning and how they compare with urban ED visits. The authors used data from the 2006 and 2013 Nationwide Emergency Department Sample to examine rural and urban opioid-related visits (ORVs) to EDs, including rate change over time, and the outcomes of these ED visits (treatment and release, inpatient admission, transfer, and death). Study findings showed that ORVs as a proportion of total visits increased in rural and urban EDs between 2006 and 2013; rural ORV rates were lower than urban rates in both time periods, however this difference narrowed because of somewhat higher rural increases. Additionally, rural ORVs were more likely than those in urban areas to be by patients 65 and older and to involve concurrent use of benzodiazepines. One fifth of ORVs by rural residents occurred in urban EDs and rural EDs were more likely to transfer patients to another hospital. More research is needed to understand the impact of rural residents’ treatment in urban EDs or other facilities on short- and long-term outcomes for patients who experience an ORV. For more information on this study, please contact Dr. Erika ZIller, [email protected]

Bicyclic Boronate β-Lactamase Inhibitors: The Present Hope against Deadly Bacterial Pathogens

The use of β-lactamase inhibitors in combination with β-lactam antibiotics is an emerging area in drug discovery. This strategy allows the restoration of the therapeutic efficacy of these antibiotics in clinical use against multiresistant bacteria. These pathogens are drug resistant because they express β-lactamase enzymes, which prevent the antibiotic therapeutic action by catalyzing the hydrolysis of the β-lactam ring. These enzymes are quite diverse in both their structural architecture and hydrolytic capability, as well as in the mechanism of action. The ever-increasing emergence of pathogens that are capable of coproducing different types of β-lactamases has triggered the search for ultrabroad-spectrum inhibitors capable of deactivating both serine- and metallo-β-lactamases. A recent breakthrough in this long-pursued and unmet need is the discovery of bicyclic boronate inhibitors, specifically taniborbactam, VNRX-7145, and QPX7728, which are currently under clinical development in combination with cefepime, ceftibuten, and QPX2014, respectively. The present article highlights the therapeutic potential of these inhibitors and their spectrum of efficacy is compared with those of other β-lactam/β-lactamase inhibitor combinations recently approved by the food and drug administration. The molecular basis of the ultrabroad-spectrum of activity of boron-based inhibitors is also discussed, on the basis of the available crystal structures and the results of computational studiesinancial support from the Spanish Ministry of Economy and Competiveness (SAF2016-75638-R, PID2019-105512RB-I00), the Xunta de Galicia [ED431B 2018/04 and Centro singular de investigación de Galicia accreditation 2019–2022 (ED431G 2019/03)], and the European Regional Development Fund (ERDF) is gratefully acknowledgedS

Kinstate intervention in ethnic conflicts : Albania and Turkey compared

Albania and Turkey did not act in overtly irredentist ways towards their ethnic brethren in neighboring states after the end of communism. Why, nonetheless, did Albania facilitate the increase of ethnic conflict in Kosovo and Macedonia, while Turkey did not, with respect to the Turks of Bulgaria? I argue that kin-states undergoing transition are more prone to intervene in external conflicts than states that are not, regardless of the salience of minority demands in the host-state. The transition weakens the institutions of the kin-state. Experiencing limited institutional constraints, self-seeking state officials create alliances with secessionist and autonomist movements across borders alongside their own ideological, clan-based and particularistic interests. Such alliances are often utilized to advance radical domestic agendas. Unlike in Albania's transition environment, in Turkey there were no emerging elites that could potentially form alliances and use external movements to legitimize their own domestic existence or claims