Evaluation of Narrow-band imaging (NBI) with magnification colonoscopy for improving the diagnostic accuracy of the investigation

In last years many new endoscopic methods, as well as NBI have been introduced with aim to improve the diagnostic accuracy of colonoscopy. The data for their utility to be introduced in the routine clinical practice are not enough yet. The aim of this study was to evaluate the advantages of NBI with magnifying endoscopy compared to conventional colonoscopy for improving the diagnostic accuracy of endoscopic investigation. We analyzed the results of 330 patients with single or multiple (up to 5) colonic lesions found during standard colonoscopy (n=1530), and by magnifying NBI (n=2329Olympus Exera 180). With the use of magnifying endoscopy 799 new lesions were found, mainly benign lesions with size 5 mm (ð<0.001). Early cancer or high grade dysplasia was found in 4 new diagnosed lesions (total n=104), and low-grade - in 12 (total n=318). There was a significant correlation between the histological diagnosis and pit pattern of colonic mucosa according to the classification of S. Kudo et al. (ð<0.001), as well as the type of microvascular architecture, applying the classification of Y. Sano et al. (ð < 0.001). The diagnostic accuracy of NBI magnifying colonoscopy for prediction of the histological changes, evaluating the pit pattern type and type of capillary vessels was 92% and 96% for invasive adenocarcinoma, 95% and 87% - for early cancer or high-grade dysplasia, and between 95 - 100% - for benign lesions, respectively. In conclusion, NBI magnifying endoscopy is a promising method for the diagnosis of small colon lesions, especially for those with size less than 5 mm, and for the differentiation between neoplastic and non-neoplastic colon lesions, as well as the lesions with low-grade and high grade dyplasia or early colorectal carcinoma. In addition, it allows distinction of noninvasive from the invasive cancer

X(3): An Exactly Separable Gamma-Rigid Version of the X(5) Critical Point Symmetry

A gamma-rigid version (with gamma=0) of the X(5) critical point symmetry is constructed. The model, to be called X(3) since it is proved to contain three degrees of freedom, utilizes an infinite well potential, is based on exact separation of variables, and leads to parameter free (up to overall scale factors) predictions for spectra and B(E2) transition rates, which are in good agreement with existing experimental data for 172-Os and 186-Pt. An unexpected similarity of the first beta bands of the X(5) nuclei 150-Nd, 152-Sm, 154-Gd, and 156-Dy to the X(3) predictions is observed.Comment: LaTeX, 12 pagres, including 4 postscript figure

Unified description of magic numbers of metal clusters in terms of the 3-dimensional q-deformed harmonic oscillator

Magic numbers predicted by a 3-dimensional q-deformed harmonic oscillator with Uq(3)>SOq(3) symmetry are compared to experimental data for atomic clusters of alkali metals (Li, Na, K, Rb, Cs), noble metals (Cu, Ag, Au), divalent metals (Zn, Cd), and trivalent metals (Al, In), as well as to theoretical predictions of jellium models, Woods-Saxon and wine bottle potentials, and to the classification scheme using the 3n+l pseudo quantum number. In alkali metal clusters and noble metal clusters the 3-dimensional q-deformed harmonic oscillator correctly predicts all experimentally observed magic numbers up to 1500 (which is the expected limit of validity for theories based on the filling of electronic shells), while in addition it gives satisfactory results for the magic numbers of clusters of divalent metals and trivalent metals, thus indicating that Uq(3), which is a nonlinear extension of the U(3) symmetry of the spherical (3-dimensional isotropic) harmonic oscillator, is a good candidate for being the symmetry of systems of several metal clusters. The Taylor expansions of angular momentum dependent potentials approximately producing the same spectrum as the 3-dimensional q-deformed harmonic oscillator are found to be similar to the Taylor expansions of the symmetrized Woods-Saxon and wine-bottle symmetrized Woods-Saxon potentials, which are known to provide successful fits of the Ekardt potentials.Comment: 23 pages including 7 table

Extramedullary (Solitary) Plasmocytomas in Otorhinolaryngology. Presentation of Тwo Clinical Cases

Екстрамедуларните (солитарни) плазмоцитоми принадлежат към групата на лимфопролиферативните заболявания и се разглеждат паралелно с НХЛ. Плазмоцитният лимфом се развива най-често мултилокуларно, но в областта на ORL-органите (предимно в нос и околоносни кухини, епифаринкс, мезофаринкс, ларинкс и др.) като правило се представят като солитарни екстрамедуларни плазмоцитоми. Той се среща 2–3 пъти по-често при мъжете около 5-та до 7-та декада. Представяме два клинични случая: 66-годишен пациент с екстрамедуларен (солитарен) плазмоцитом на епифаринкса; 63-годишен пациент с екстрамедуларен (солитарен) плазмоцитом на ларинкса (епиглотиса).----------------------------------------------Extramedullary (solitary) plasmocytomas belongs to the group of lymphoproliferative diseases and they are discussed parallel with NHL. In most cases plasmocytic lymphoma possess multilacunar growth pattern, but in ORL area (nose and paranasal cavities, epipharynx, mesopharynx, larynx, etc.) grows as a rule as solitary extramedullary plasmocytoma. It’s frequency is 2-3 times greater in men between 5th and 7th decade. We present two clinical cases: 66 years old patient with extramedullary (solitary) plasmocytoma in epipharynx; 63 years old patient with extramedullary (solitary) plasmocytoma of laryngeal glottic area