Diversity of rodents and treeshrews in different habitats in western Sarawak, Borneo.

A diverse community of 63 rodent species and nine treeshrew species are found in Borneo (Phillipps & Phillipps, 2016). They play an important role in providing ecosystem services by contributing to pollination, seed dispersal, and germination; and also food for larger carnivores (Shanahan & Compton, 2000; Morand et al., 2006; Payne & Francis, 2007; Phillipps & Phillipps, 2016). Bornean tropical forests have been lost, degraded, and fragmented by anthropogenic activities since the early 1970s (Bryan et al., 2013; Gaveau et al., 2014), consequently created new or alternative habitats for rodents and treeshrews especially resilient, adaptive, or opportunistic species that can thrive in such disturbed areas while forest-dependent species would decline in number or become locally extinct (Traweger et al., 2006; Palmeirim et al., 2020). This study was conducted to determine the species richness and abundance of rodents and treeshrews in four different habitats (i.e. forest, oil palm plantation, rural villages, and urban area) in the western part of Sarawak, Borneo. The data collected from this study is important and useful in contributing new knowledge on the occupancy of anthropogenically created habitats for rodents and treeshrews and gives an insight into how each rodent and treeshrew species responded to human disturbance in term of their species richness and abundance in each habitat type

Selective deletion of PPARβ/δ in fibroblasts causes dermal fibrosis by attenuated LRG1 expression.

Connective tissue diseases of the skin are characterized by excessive collagen deposition in the skin and internal organs. Fibroblasts play a pivotal role in the clinical presentation of these conditions. Nuclear receptor peroxisome-proliferator activated receptors (PPARs) are therapeutic targets for dermal fibrosis, but the contribution of the different PPAR subtypes are poorly understood. Particularly, the role of fibroblast PPARβ/δ in dermal fibrosis has not been elucidated. Thus, we generated a mouse strain with selective deletion of PPARβ/δ in the fibroblast (FSPCre- <i>Pparb/d</i> <sup>-/-</sup> ) and interrogated its epidermal and dermal transcriptome profiles. We uncovered a downregulated gene, leucine-rich alpha-2-glycoprotein-1 ( <i>Lrg1</i> ), of previously unknown function in skin development and architecture. Our findings suggest that the regulation of <i>Lrg1</i> by PPARβ/δ in fibroblasts is an important signaling conduit integrating PPARβ/δ and TGFβ1-signaling networks in skin health and disease. Thus, the FSPCre- <i>Pparb/d</i> <sup>-/-</sup> mouse model could serve as a novel tool in the current gunnery of animal models to better understand dermal fibrosis

Metabolism-related pharmacokinetic drug-drug interactions with tyrosine kinase inhibitors: Current understanding, challenges and recommendations

10.1111/bcp.12496British Journal of Clinical Pharmacology792241-25

Risk of tyrosine kinase inhibitors-induced hepatotoxicity in cancer patients: A meta-analysis

10.1016/j.ctrv.2012.09.004Cancer Treatment Reviews392199-206CTRE

Study of implanted boron distribution in p+n structures using scanning capacitance microscopy

10.1117/12.405388Proceedings of SPIE - The International Society for Optical Engineering4227175-183PSIS

Educational pamphlets for improving uptake of cancer screening: A systematic review

10.1071/HC18093Journal of Primary Health Care113207-21

Purification and renaturation of recombinant human lymphotoxin (tumour necrosis factor beta) expressed in Escherichia coli as inclusion bodies

10.1002/jctb.280590111Journal of Chemical Technology and Biotechnology59167-72JCTB