Reciclaje de residuos sólidos y su influencia en la gestión ambiental en la municipalidad distrital de Víctor Larco Herrera

The purpose of this work is to determine the influence of solid waste recycling on the environmental management of the district municipality of Víctor Larco Herrera, 2021; This study was based on the non-experimental descriptive correlational design methods, for which 371 heads of families were used as a sample size for the application of the instruments during the collection of information. The data obtained were processed through the statistical software for social sciences SPSS V23. Likewise, the results found are shown in tables and statistical figures in an orderly and detailed manner. It is concluded that there is a significant influence between the level of recycling of solid waste and the Level of Environmental Management in the inhabitants of Víctor Larco Herrera, thanks to the value of the Spearman coefficient test at a level of significance (p<0.05) .El presente trabajo tiene por finalidad determinar la influencia del reciclaje de residuos sólidos en la gestión ambiental de la municipalidad distrital de Víctor Larco Herrera, 2021; dicho estudio se basó en los métodos del diseño no experimental de tipo correlacional descriptivo, para ello se contó con 371 jefes de familia como tamaño de muestra para la aplicación de los instrumentos durante la recolección de información. Los datos obtenidos fueron procesados a través del software de estadística para ciencias sociales SPSS V23. Así mismo los resultados encontrados se muestran en tablas y figuras estadísticas de forma orde-nada y detallada. Se concluye que existe influencia significativa entre el nivel de reciclaje de residuos sólidos y el Nivel de Gestión Ambiental en los habitantes de Víctor Larco Herrera, gracias al valor de la prueba de coefi-ciente de spearman a un nivel de significancia (p<0.05)

Clonal chromosomal mosaicism and loss of chromosome Y in elderly men increase vulnerability for SARS-CoV-2

The pandemic caused by severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2, COVID-19) had an estimated overall case fatality ratio of 1.38% (pre-vaccination), being 53% higher in males and increasing exponentially with age. Among 9578 individuals diagnosed with COVID-19 in the SCOURGE study, we found 133 cases (1.42%) with detectable clonal mosaicism for chromosome alterations (mCA) and 226 males (5.08%) with acquired loss of chromosome Y (LOY). Individuals with clonal mosaic events (mCA and/or LOY) showed a 54% increase in the risk of COVID-19 lethality. LOY is associated with transcriptomic biomarkers of immune dysfunction, pro-coagulation activity and cardiovascular risk. Interferon-induced genes involved in the initial immune response to SARS-CoV-2 are also down-regulated in LOY. Thus, mCA and LOY underlie at least part of the sex-biased severity and mortality of COVID-19 in aging patients. Given its potential therapeutic and prognostic relevance, evaluation of clonal mosaicism should be implemented as biomarker of COVID-19 severity in elderly people. Among 9578 individuals diagnosed with COVID-19 in the SCOURGE study, individuals with clonal mosaic events (clonal mosaicism for chromosome alterations and/or loss of chromosome Y) showed an increased risk of COVID-19 lethality

Compilación de Proyectos de Investigacion de 1984-2002

Instituto Politecnico Nacional. UPIICS

International Nosocomial Infection Control Consortiu (INICC) report, data summary of 43 countries for 2007-2012. Device-associated module

We report the results of an International Nosocomial Infection Control Consortium (INICC) surveillance study from January 2007-December 2012 in 503 intensive care units (ICUs) in Latin America, Asia, Africa, and Europe. During the 6-year study using the Centers for Disease Control and Prevention's (CDC) U.S. National Healthcare Safety Network (NHSN) definitions for device-associated health care–associated infection (DA-HAI), we collected prospective data from 605,310 patients hospitalized in the INICC's ICUs for an aggregate of 3,338,396 days. Although device utilization in the INICC's ICUs was similar to that reported from ICUs in the U.S. in the CDC's NHSN, rates of device-associated nosocomial infection were higher in the ICUs of the INICC hospitals: the pooled rate of central line–associated bloodstream infection in the INICC's ICUs, 4.9 per 1,000 central line days, is nearly 5-fold higher than the 0.9 per 1,000 central line days reported from comparable U.S. ICUs. The overall rate of ventilator-associated pneumonia was also higher (16.8 vs 1.1 per 1,000 ventilator days) as was the rate of catheter-associated urinary tract infection (5.5 vs 1.3 per 1,000 catheter days). Frequencies of resistance of Pseudomonas isolates to amikacin (42.8% vs 10%) and imipenem (42.4% vs 26.1%) and Klebsiella pneumoniae isolates to ceftazidime (71.2% vs 28.8%) and imipenem (19.6% vs 12.8%) were also higher in the INICC's ICUs compared with the ICUs of the CDC's NHSN