Phraseological units containing numbers in the general system of pu classifications

The article presents semantic and structural types of phraseological units containing numbers in the Russian and English languages. The classifications of phraseological units of this type according to their origin and functioning are also considered.В статье рассматриваются семантические и структурные типы фразеологизмов с числовым компонентом в русском и английском языках, а также классификации данной группы фразеологизмов с точки зрения их происхождения и функционирования в языке

Criminal-legal assessment of euthanasia

Still in Russia and abroad, questions about implementation of the right to life and right to death are controversial, and as a consequence, the threat of killing the person by the use of euthanasia does not cease to be relevant. Russian criminal law provides criminal responsibility for the murder, which is a variety of ways, however, standards meeting the requirements of the safe existence of terminally ill people, including those not able to be fully aware of the incurability of the disease, is not provided. The legislator attempted criminal prohibitions of the use of euthanasia, however, in the current criminal law of the Russian Federation the data of rules. In this connection, many questions of law enforcement practice in the sphere of criminal-law protection of the safety of life and human health remain uncertain. The given circumstances testify to the fact that the study of issues of qualification of crimes against life and health becomes more fundamental. The article analyzes the problematic issues of demarcation of euthanasia from murder and suicide, and the author's article, providing for the criminal-legal prohibition of the use of euthanasia that will contribute to the improvement of law enforcement practice

The Role of Evaluative Tools in the Creation of the Memorial Media Portrait of Jacques Chirac (1932—2019)

The article is devoted to the study of evaluative tools used in modern French media in order to form the media image of a representative of the political elite. The techniques used in the creation of a memorial media portrait of Jacques Chirac (1932—2019), President of France from 1995 to 2007 are considered. The research material was the most prestigious French print media of various political orientations, published in late September — early October 2019 in connection with the death of the ex-President of the French Republic. The relevance of the research topic is dictated by the close attention of modern linguistics to axiological phenomena, differently presented in different types of discursive practices. The novelty of the study is due to the appeal to the analysis of the complex of evaluation tools used in the French print media when characterizing the former leader of the state during the nation’s farewell period. The estimated potential of the title of the article and its influence on the formation of the estimated vector of the entire text of the publication are shown. A systematic analysis of the assessment expression means, reflected in the memorial media portrait of the politician, is given. The factors that influenced the peculiarities of their use in this type of media portrait are revealed

Recovery of motor function of the hand of stroke patients using the "Hand tutor"

Devices with biologically feedback (biofeedback) are widely used in the rehabilitation of patients after stroke. The patient after a stroke in the carotid arteries loses two-handed operation, which is associated with the manipulation of objects and the many social and professional functions. An important factor in rehabilitation is to restore the function of the brush, as the most important organ of social and professional activities of the person. The use of biofeedback devices to restore function of the hand is the most expedient and efficient manner. A pilot study showed a positive trend on the basic scales of neurological deficit and scale spasticity on restoration of function of the hand in patients after carotid strokes. The maximum effect was achieved in the group of patients receiving comprehensive rehabilitation program (gymnastics, psammotherapy, therapeutic massage) with using the apparatus of bare 'Hand Tutor*. Further study is required of the effectiveness of this method with selection methods and duration of therapy.Аппараты с биологически обратной связью (БОС) широко используются в реабилитации пациентов после инсультов. Пациент после инсульта в каротидном бассейне теряет возможность двуручной работы, которая связана с манипуляцией предметами и множеством социальных и профессиональных функций. Важным фактором в реабилитации является восстановления функции кисти, как наиболее важного органа социальной и профессиональной деятельности человека. Использование аппаратов БОС с целью восстановления функции кисти наиболее целесообразно и эффективно. Проведенное пилотное исследование продемонстрировало положительную динамику по основным шкалам неврологического дефицита - Бартела, Ривермид и шкале спастичностиАшфорта по восстановлению функции кисти у пациентов после каротидных инсультов. Наибольший эффект достигнут в группе пациентов, получавших комплексную реабилитационную программу (лечебная гимнастика, псаммотерапию, лечебный массаж) с использованием аппарата БОС «HandTutor». Требуется дальнейшее изучение эффективности данного метода с подбором методик и длительности терапии

Assessing the effectiveness of current methods of hand function recovery in patients who underwent ischemic stroke

In order to assess the post-ischemic-stroke effectiveness of hand function recovery in the rehabilitation center environment, 91 patients were involved in examination. The patients were uniformly distributed into three groups. Groups differed by the applied methods: 1) conventional hand exercises; 2) biofeedback-driven “HandTutorTM" recovery methods; 3) biofeedback- driven “HandTutorTM" recovery methods paired with transcranial magnetic stimulation, TMS. The levels of hand function improvement were assessed using: the function scale, the life activities scale, and “HandTutorTM" tests. The derived data indicate statistically reliable hand function improvement in the patients of all three groups after the 12-day treatment course. However, the degree of improvement in both second and third groups is more significant. Thus, we see the evidential improvement in the effectiveness of post-ischemic-stroke hand function recovery when applying the current rehabilitation methods including “HandTutorTM” and TMS.С целью оценки эффективности восстановления функции кисти в условиях реабилитационного центра у пациентов после ишемического инсульта (ИИ) были обследованы 91 человек, равномерно распределённых по трём группам, отличающимся применяемыми методиками. В первой группе использовалась традиционная лечебная гимнастика для кисти, во второй группе занятия на аппарате с биологической обратной связью «HandTutorTM», в третьей группе занятия на аппарате с биологической обратной связью «HandTutorTM» были подкреплены лечебными процедурами транскраниальной магнитной стимуляции (ТМС). Изменения функции кисти в динамике измерялись с помощью шкал оценки функции и жизнедеятельности и тестов аппарата «HandTutorTM». Полученные данные свидетельствуют о достоверном улучшении функции кисти у пациентов за 12 дней лечения во всех трех группах. При сравнении было выявлено более значимое улучшение показателей во второй и третьей группах пациентов. Применение современных технологий аппарата с биологической обратной связью «HandTutorTM» и ТМС позволяет повысить эффективность реабилитационных мероприятий по восстановлению функции кисти после ИИ

The role of the sinuvertebral nerve damage at the cervical level in the development of chronic pain after a whipsplash injury and its osteopathic correction

The purpose of the study is to research the anatomical features of the sinuvertebral nerve and the possibility of clinical using of the obtained data in the practice of an osteopath and a neurologist.Цель исследования – изучить анатомические особенности синувертебрального нерва и возможность клинического применения полученных данных в практике врача остеопата и невролога

Clinicopathological features of nonspecific invasive breast cancer according to its molecular subtypes

The aim of the present study was to investigate the clinical and morphological features of nonspecific invasive breast cancer according to its molecular subtypes. Materials and Methods: 163 women with nonspecific invasive breast cancer (T1–4N0–3M0) were included in the present study. Luminal A type of breast cancer was detected in 101 women, luminal B type — in 23 women, overexpression of HER2/neu was identified in 14 women and triple-negative cancer — in 25 women. Results: The study revealed that various molecular subtypes of breast cancer differ in the morphological structure, the expression characteristics of the primary tumor and the rate of lymphogenous and hematogenous metastasis. Lymphogenous metastases were more frequently (in 71%) detected in HER2/neu overexpressing breast cancer than in luminal A (41%), luminal B (39%) and triple-negative tumors (40%). Hematogenous metastasis did not depend on the morphological structure of carcinoma infiltrative component, the state of tumor stroma as well as the proliferative activity in all the investigated groups. Conclusion: The revealed clinicopathological characteristics of different molecular subtypes of invasive breast cancer allow to predict the possible outcome of the disease and select personalized treatment strategy for patients more reasonably

Features receptor status of tumor in synchronous and metachronous bilateral breast cancer

The work examines the characteristics of the receptor status of the tumor with synchronous and metachronous bilateral breast cancer. Studied surgical material from 44 patients with bilateral malignant tumors of this localization: 22 patients were recorded synchronous and 22 patients metachronous breast tumors. The predominant histological type was invasive carcinoma nonspecific type. We conducted immunohistochemical examination of the tumor tissue showed that in synchronous bilateral breast cancer is dominated by positive receptor status with the simultaneous combination of the expression of receptors for estrogen and progesterone, and the most common is the luminal A molecular genetic type of neoplasm. Metachronous tumors significantly more likely to have a negative receptor status with the lack of expression of receptors for estrogen and progesterone, and dominant among them is three times the negative molecular genetic type of tumor.Работа посвящена изучению особенностей рецепторного статуса опухоли при синхронном и метахронном билатеральном раке молочных желез. Исследовался операционный материал от 44 пациенток с двухсторонними злокачественными новообразованиями данной локализации: у 22 больных регистрировались синхронные и у 22 пациенток метахронные опухоли молочных желез. Преобладающим гистологическим типом опухоли была инвазивная карцинома неспецифического типа. Проведенное нами иммуногистохимическое исследование ткани опухоли показало, что при синхронном билатеральном раке молочных желез преобладает позитивный рецепторный статус с одновременным сочетанием экспрессии рецепторов к эстрогенам и прогестерону, а наиболее частым является люминальный А молекулярно­генетический тип новообразования. Метахронные опухоли достоверно чаще имеют негативный рецепторный статус с отсутствием экспрессии рецепторов к эстрогенам и прогестерону, а доминирующим среди них является трижды негативный молекулярно-генетический тип опухоли