Field induced magnetic transition and metastability in Co substituted Mn2SbMn_{2}Sb

A detailed investigation of first order ferrimagnetic (FRI) to antiferromagnetic (AFM) transition in Co (15%) doped $Mn_2Sb$ is carried out. These measurements demonstrate anomalous thermomagnetic irreversibility and glass-like frozen FRI phase at low temperatures. The irreversibility arising between the supercooling and superheating spinodals is distinguised in an ingenious way from the irreversibility arising due to kinetic arrest. Field annealing measurements shows reentrant FRI-AFM-FRI transition with increasing temperature. These measurements also show that kinetic arrest band and supercooling band are anitcorrelated i.e regions which are kinetically arrested at higher temperature have lower supercooling temperature and vice versa.Comment: 10 pages, 8 figure

Low temperature magnetization and resistivity measurements in Co based soft magnetic microwires

Magnetization and resistivity measurements, embracing a temperature range 2-300 K, have been performed in glass-coated Co6sMnTSiloBls amorphous microwires. The relation between both types of measurements is analysed. Similar trends of the temperature dependence of the domain structure, magnetization and resistivity are observed. An increase of resistance is found for the saturated state. This increase of the resistivity is analysed in terms of the domainstructure and the presence of domain walls.Postprint (published version

Remote sensing detection of nutrient uptake in vineyards using narrow-band hyperspectral imagery

This manuscript delves further into the assessment of narrow-band vegetation indices derived from hyperspectral imagery acquired at 1 m spatial resolution with the Compact Airborne Spectrographic Imager (CASI). Narrow-band indices proposed in this study were assessed as indicators of biochemical and structural parameters in Vitis vinifera L., observing their relationships with foliar variables such as N, P, K, Ca, Fe, Mg and chlorophyll a+b concentration (Ca+b). Hyperspectral indices were assessed to study their capability for vegetation condition monitoring as a function of fertilization treatments applied (basically extracts of Ascophyllum nodosum seaweed and chelates), showing associations with field variables. Narrow-band vegetation indices displayed sensitivity to vineyard growth and condition as a function of seaweed fertilization and other supplementary mineral correctors, such as chelates. This work shows the interest of using new narrow-band hyperspectral remote sensing indices for vineyard monitoring due to their potential to indicate physiological condition.

Surgery guided by 5-aminolevulinic fluorescence in glioblastoma: volumetric analysis of extent of resection in singlecenter experience

We analyzed the efficacy and applicability of surgery guided by 5-aminolevulinic acid (ALA) fluorescence in consecutive patients with glioblastoma multiforme (GBM). Thirty-six patients with GBM were operated on using ALA fluorescence. Resections were performed using the fluorescent light to assess the right plane of dissection. In each case, biopsies with different fluorescent quality were taken from the tumor center, from the edges, and from the surrounding tissue. These samples were analyzed separately with hematoxylin-eosin examination and immunostaining against Ki67. Tumor volume was quantified with pre- and postoperative volumetric magnetic resonance imaging. Strong fluorescence identified solid tumor with 100% positive predictive value. Invaded tissue beyond the solid tumor mass was identified by vague fluorescence with 97% positive predictive value and 66% negative predictive value, measured against hematoxylin-eosin examination. All the contrast-enhancing volume was resected in 83.3% of the patients, all patients had resection over 98% of the volume and mean volume resected was 99.8%. One month after surgery there was no mortality, and new or increased neurological morbidity was 8.2%. The fluorescence induced by 5-aminolevulinic can help to achieve near total resection of enhancing tumor volume in most surgical cases of GBM. It is possible during surgery to obtain separate samples of the infiltrating cells from the tumor borde

Oncolytic viruses as therapeutic tools for pediatric brain tumors

In recent years, we have seen an important progress in our comprehension of the molecular basis of pediatric brain tumors (PBTs). However, they still represent the main cause of death by disease in children. Due to the poor prognosis of some types of PBTs and the long-term adverse effects associated with the traditional treatments, oncolytic viruses (OVs) have emerged as an interesting therapeutic option since they displayed safety and high tolerability in pre-clinical and clinical levels. In this review, we summarize the OVs evaluated in different types of PBTs, mostly in pre-clinical studies, and we discuss the possible future direction of research in this field. In this sense, one important aspect of OVs antitumoral effect is the stimulation of an immune response against the tumor which is necessary for a complete response in preclinical immunocompetent models and in the clinic. The role of the immune system in the response of OVs needs to be evaluated in PBTs and represents an experimental challenge due to the limited immunocompetent models of these diseases available for pre-clinical research