134 research outputs found
Fabrication of Resorcinol-Formaldehyde Xerogel based High Aspect Ratio 3-D Hierarchical C-MEMS Structures
We demonstrate a novel method to fabricate arrays of resorcinol-
formaldehyde xerogel (RFX) based high aspect ratio (HAR) three-
dimensional (3-D) hierarchical C-MEMS structures. Starting from
a master pattern of HAR 3-D posts fabricated in SU-8 negative
photoresist by photolithography, a negative PDMS stamp with
arrays of holes was prepared by micromolding. The PDMS stamp
was then used to fabricate HAR 3-D RFX posts by replica molding.
The 3-D RFX posts thus fabricated were electrosprayed with SU-8
or an RF sol in the form of submicron or nano sized droplets and
followed by pyrolysis to yield HAR 3-D hierarchical carbon posts.
To characterize their use in C-MEMS based batteries,
galvanostatic (charge and discharge) experiments on RFX derived
carbon showed that it can be reversibly intercalated with Li ions
and possesses superior intercalation properties as compared to SU-
8 derived carbon which is a widely used material in C-MEMS
Micro-fabrication of Carbon Structures by Pattern Miniaturization in Resorcinol-Formaldehyde Gel
A simple and novel method to fabricate and miniaturize surface and
sub-surface micro-structures and micro-patterns in glassy carbon is proposed
and demonstrated. An aqueous resorcinol-formaldehyde (RF) sol is employed for
micro-molding of the master-pattern to be replicated, followed by controlled
drying and pyrolysis of the gel to reproduce an isotropically shrunk replica in
carbon. The miniaturized version of the master-pattern thus replicated in
carbon is about one order of magnitude smaller than original master by
repeating three times the above cycle of molding and drying. The
micro-fabrication method proposed will greatly enhance the toolbox for a facile
fabrication of a variety of Carbon-MEMS and C-microfluidic devices.Comment: 16 pages, 5 figure
The class of the locus of intermediate Jacobians of cubic threefolds
We study the locus of intermediate Jacobians of cubic threefolds within the
moduli space of complex principally polarized abelian fivefolds, and its
generalization to arbitrary genus - the locus of abelian varieties with a
singular odd two-torsion point on the theta divisor. Assuming that this locus
has expected codimension (which we show to be true for genus up to 5), we
compute the class of this locus, and of is closure in the perfect cone toroidal
compactification, in the Chow, homology, and the tautological ring.
We work out the cases of genus up to 5 in detail, obtaining explicit
expressions for the classes of the closures of the locus of products of an
elliptic curve and a hyperelliptic genus 3 curve, in moduli of principally
polarized abelian fourfolds, and of the locus of intermediate Jacobians in
genus 5. In the course of our computation we also deal with various
intersections of boundary divisors of a level toroidal compactification, which
is of independent interest in understanding the cohomology and Chow rings of
the moduli spaces.Comment: v2: new section 9 on the geometry of the boundary of the locus of
intermediate Jacobians of cubic threefolds. Final version to appear in
Invent. Mat
Management of Low-Grade Glioma
The optimal management of patients with low-grade glioma (LGG) is controversial. The controversy largely stems from the lack of well-designed clinical trials with adequate follow-up to account for the relatively long progression-free survival and overall survival of patients with LGG. Nonetheless, the literature increasingly suggests that expectant management is no longer optimal. Rather, there is mounting evidence supporting active management including consideration of surgical resection, radiotherapy, chemotherapy, molecular and histopathologic characterization, and use of modern imaging techniques for monitoring and prognostication. In particular, there is growing evidence favoring extensive surgical resection and increasing interest in the role of chemotherapy (especially temozolomide) in the management of these tumors. In this review, we critically analyze emerging trends in the literature with respect to management of LGG, with particular emphasis on reports published during the past year
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Comparative phylogenetic methods and the cultural evolution of medicinal plant use
Human life depends on plant biodiversity and the ways in which plants are used are culturally determined. Whilst anthropologists have used phylogenetic comparative methods (PCMs) to gain an increasingly sophisticated understanding of the evolution of political, religious, social, and material culture, plant use has been almost entirely neglected. Medicinal plants are of special interest because of their role in maintaining people’s health across the world. PCMs in particular, and cultural evolutionary theory in general, provide a framework in which to study the diversity of medicinal plant applications cross-culturally, and to infer changes in plant use through time. These methods can be applied to single medicinal plants as well as the entire set of plants used by a culture for medicine, and they account for the non-independence of data when testing for floristic, cultural or other drivers of plant use. With cultural, biological, and linguistic diversity under threat, gaining a deeper and broader understanding of the variation of medicinal plant use through time and space is pressing
International Lower Limb Collaborative (INTELLECT) study: a multicentre, international retrospective audit of lower extremity open fractures
International lower limb collaborative (INTELLECT) study: a multicentre, international retrospective audit of lower extremity open fractures
Trauma remains a major cause of mortality and disability across the world1, with a higher burden in developing nations2. Open lower extremity injuries are devastating events from a physical3, mental health4, and socioeconomic5 standpoint. The potential sequelae, including risk of chronic infection and amputation, can lead to delayed recovery and major disability6. This international study aimed to describe global disparities, timely intervention, guideline-directed care, and economic aspects of open lower limb injuries
International Lower Limb Collaborative (INTELLECT) study : a multicentre, international retrospective audit of lower extremity open fractures
Accelerated surgery versus standard care in hip fracture (HIP ATTACK): an international, randomised, controlled trial
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