A Survey of Theories of the Family

This review explores the theory of household technology and the associated possibilities for distributing utility among household members. It also explores decision theory within the household, drawing on standard consumer decision theory. The review discusses models of equilbrium in which families are formed by persons voluntarily choosing mates. This theory is analogous to ``Tiebout theory'' in urban economics, where the objects of choice include not only the amount of public goods supplied in each city, but also which individuals live in each place. An aspect of family life that has fewer parallels in the economics of market economies is intrafamilial affection. The final section of this paper reviews a growing theoretical literature on love, altruism and the family.Center for Research on Economic and Social Theory, Department of Economics, University of Michiganhttp://deepblue.lib.umich.edu/bitstream/2027.42/101098/1/ECON082.pd

Retrospective evaluation of whole exome and genome mutation calls in 746 cancer samples

Funder: NCI U24CA211006Abstract: The Cancer Genome Atlas (TCGA) and International Cancer Genome Consortium (ICGC) curated consensus somatic mutation calls using whole exome sequencing (WES) and whole genome sequencing (WGS), respectively. Here, as part of the ICGC/TCGA Pan-Cancer Analysis of Whole Genomes (PCAWG) Consortium, which aggregated whole genome sequencing data from 2,658 cancers across 38 tumour types, we compare WES and WGS side-by-side from 746 TCGA samples, finding that ~80% of mutations overlap in covered exonic regions. We estimate that low variant allele fraction (VAF < 15%) and clonal heterogeneity contribute up to 68% of private WGS mutations and 71% of private WES mutations. We observe that ~30% of private WGS mutations trace to mutations identified by a single variant caller in WES consensus efforts. WGS captures both ~50% more variation in exonic regions and un-observed mutations in loci with variable GC-content. Together, our analysis highlights technological divergences between two reproducible somatic variant detection efforts

Big Macs and Eigenfactor Scores: Don't Let the Correlation Coefficients Fool You

A recent article by Phil Davis suggested that the Eigenvalue metric does adds little useful information to the more simply calculated measure of total citations published by the ISI. This paper argues that Davis's claim is an instance of a classic statistical fallacy of spurious correlation. Based on an analysis of the entire 2006 ISI Journal Citation Reports, we show that there are statistically and economically significant differences between the Eigenfactor metrics and the ISI's impact factor and total citations

Teaching Economics Interactively: A Cannibal's Dinner Party

This paper describes techniques that I use to teach economics principles "interactively". These techniques include classroom experiments and classroom clickers. The paper describes an experiment on market entry and gives examples of applications of classroom clickers. Clicker applications include the collection data about student preferences that can be used to construct demand curves and supply curves. Check on students' knowledge of central concepts. Play interactive games that illustrate economic concepts

Regulation of Externalities

This paper presents a general equilibrium model with marketable pollution permits. It shows that competitive equilibrium with marketable permits is "conditionally optimal" in the sense that no Pareto improvement can be achieved without changing pollution standards. The paper also explores mechanisms for choosing efficient aggregate pollution levels

Demographics and the Political Sustainability of Pay-as-you-go Social Security

The net present value of costs and benefits from a pay-as-you-go social security system are negative for young people and positive for the elderly. If people all vote their financial self-interest, there will be a pivotal age such that those who are younger favor smaller social security benefits and those who are older will favor larger benefits. For persons of each age and sex, we estimate the expected present value gained or lost from a small permanent increase in the amount of benefits, where the cost of these benefits is divided equally among the population of working age. Assuming that everyone votes his or her long run financial self-interest, and calculating the number of voters in the population of each age and sex, we can determine whether there is majority support for an increase or a decrease in social security benefits. We use statistics on the age distribution and mortality rates for the United States to explore the sensitivity of political support for social security to alternative assumptions about the discount rate, excess burden in taxation, voter participation rates, and birth, death, and migration rates. We find that a once-and-for-all decrease in benefits would be defeated by a majority of selfish voters under a wide range of parameters. We also study the predicted majority outcomes of votes on changing the retirement age

How often do economists self-archive?

To answer the question of the paper's title, we looked at the tables of contents from two recent issues of 33 economics journals and attempted to find a freely available online version of each article. We found that about 90 percent of articles in the most-cited economics journals and about 50 percent of articles in less-cited journals are available. We conduct a similar exercise for political science and find that only about 30 percent of the articles are freely available. The paper reports a regression analysis of the effects of author and article characteristics on likelihood of posing and it discusses the implications of self-archiving for the pricing of subscription-based academic journals