138 research outputs found

    A mobile data acquisition system

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    A mobile data aquisition (MobiDAQ) was developed for the ATLAS central hadronic calorimeter (TileCal). MobiDAQ has been designed in order to test the functionalities of the TileCal front-end electronics and to acquire calibration data before the final back-end electronics were built and tested. MobiDAQ was also used to record the first cosmic ray events acquired by an ATLAS subdetector in the underground experimental area

    Correlated Hybrid Fluctuations from Inflation with Thermal Dissipation

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    We investigate the primordial scalar perturbations in the thermal dissipative inflation where the radiation component (thermal bath) persists and the density fluctuations are thermally originated. The perturbation generated in this model is hybrid, i.e. it consists of both adiabatic and isocurvature components. We calculate the fractional power ratio (SS) and the correlation coefficient (cos⁡Δ\cos\Delta) between the adiabatic and the isocurvature perturbations at the commencing of the radiation regime. Since the adiabatic/isocurvature decomposition of hybrid perturbations generally is gauge-dependent at super-horizon scales when there is substantial energy exchange between the inflaton and the thermal bath, we carefully perform a proper decomposition of the perturbations. We find that the adiabatic and the isocurvature perturbations are correlated, even though the fluctuations of the radiation component is considered uncorrelated with that of the inflaton. We also show that both SS and cos⁡Δ\cos \Delta depend mainly on the ratio between the dissipation coefficient Γ\Gamma and the Hubble parameter HH during inflation. The correlation is positive (cos⁡Δ>0\cos\Delta > 0) for strong dissipation cases where Γ/H>0.2\Gamma/H >0.2, and is negative for weak dissipation instances where Γ/H<0.2\Gamma/H <0.2. Moreover, SS and cos⁡Δ\cos \Delta in this model are not independent of each other. The predicted relation between SS and cos⁡Δ\cos\Delta is consistent with the WMAP observation. Other testable predictions are also discussed.Comment: 18 pages using revtex4, accepted for publication in PR

    Scalar perturbation spectra from warm inflation

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    We present a numerical integration of the cosmological scalar perturbation equations in warm inflation. The initial conditions are provided by a discussion of the thermal fluctuations of an inflaton field and thermal radiation using a combination of thermal field theory and thermodynamics. The perturbation equations include the effects of a damping coefficient Γ\Gamma and a thermodynamic potential VV. We give an analytic expression for the spectral index of scalar fluctuations in terms of a new slow-roll parameter constructed from Γ\Gamma. A series of toy models, inspired by spontaneous symmetry breaking and a known form of the damping coefficient, lead to a spectrum with ns>1n_s>1 on large scales and ns<1n_s<1 on small scales.Comment: 12 pages, 5 figures, RevTeX 4, revised with extra figure

    Cellular interference in craniofrontonasal syndrome: Males mosaic for mutations in the x-linked EFNB1 gene are more severely affected than true hemizygotes

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    Craniofrontonasal syndrome (CFNS), an X-linked disorder caused by loss-of-function mutations of EFNB1, exhibits a paradoxical sex reversal in phenotypic severity: females characteristically have frontonasal dysplasia, craniosynostosis and additional minor malformations, but males are usually more mildly affected with hypertelorism as the only feature. X-inactivation is proposed to explain the more severe outcome in heterozygous females, as this leads to functional mosaicism for cells with differing expression of EPHRIN-B1, generating abnormal tissue boundariesa process that cannot occur in hemizygous males. Apparently challenging this model, males occasionally present with a more severe female-like CFNS phenotype. We hypothesized that such individuals might be mosaic for EFNB1 mutations and investigated this possibility in multiple tissue samples from six sporadically presenting males. Using denaturing high performance liquid chromatography, massively parallel sequencing and multiplex-ligation-dependent probe amplification (MLPA) to increase sensitivity above standard dideoxy sequencing, we identified mosaic mutations of EFNB1 in all cases, comprising three missense changes, two gene deletions and a novel point mutation within the 5 untranslated region (UTR). Quantification by Pyrosequencing and MLPA demonstrated levels of mutant cells between 15 and 69. The 5 UTR variant mutates the stop codon of a small upstream open reading frame that, using a dual-luciferase reporter construct, was demonstrated to exacerbate interference with translation of the wild-type protein. These results demonstrate a more severe outcome in mosaic than in constitutionally deficient males in an X-linked dominant disorder and provide further support for the cellular interference mechanism, normally related to X-inactivation in females. © The Author 2013. Published by Oxford University Press. All rights reserved

    Cosmological parameters from SDSS and WMAP

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    We measure cosmological parameters using the three-dimensional power spectrum P(k) from over 200,000 galaxies in the Sloan Digital Sky Survey (SDSS) in combination with WMAP and other data. Our results are consistent with a ``vanilla'' flat adiabatic Lambda-CDM model without tilt (n=1), running tilt, tensor modes or massive neutrinos. Adding SDSS information more than halves the WMAP-only error bars on some parameters, tightening 1 sigma constraints on the Hubble parameter from h~0.74+0.18-0.07 to h~0.70+0.04-0.03, on the matter density from Omega_m~0.25+/-0.10 to Omega_m~0.30+/-0.04 (1 sigma) and on neutrino masses from <11 eV to <0.6 eV (95%). SDSS helps even more when dropping prior assumptions about curvature, neutrinos, tensor modes and the equation of state. Our results are in substantial agreement with the joint analysis of WMAP and the 2dF Galaxy Redshift Survey, which is an impressive consistency check with independent redshift survey data and analysis techniques. In this paper, we place particular emphasis on clarifying the physical origin of the constraints, i.e., what we do and do not know when using different data sets and prior assumptions. For instance, dropping the assumption that space is perfectly flat, the WMAP-only constraint on the measured age of the Universe tightens from t0~16.3+2.3-1.8 Gyr to t0~14.1+1.0-0.9 Gyr by adding SDSS and SN Ia data. Including tensors, running tilt, neutrino mass and equation of state in the list of free parameters, many constraints are still quite weak, but future cosmological measurements from SDSS and other sources should allow these to be substantially tightened.Comment: Minor revisions to match accepted PRD version. SDSS data and ppt figures available at http://www.hep.upenn.edu/~max/sdsspars.htm

    Human toxocariasis: contribution by Brazilian researchers

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    In the present paper the main aspects of the natural history of human infection by Toxocara larvae that occasionally result in the occurrence of visceral and/or ocular larva migrans syndrome were reviewed. The contribution by Brazilian researchers was emphasized, especially the staff of the Tropical Medicine Institute of SĂŁo Paulo (IMT)
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