2,990 research outputs found

    Study of Determined Town and Village Green Applications: Final Report to Common Land Team, Defra

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    The purpose of the research, as set out in the Project Brief, was to ‘examine a sample of the sites which have been registered as town or village greens (TVGs) since January 2004 as well as a sample of those that have not been registered’. The common term for both successful and unsuccessful applications is that either outcome has been ‘determined’ by Commons Registration Authority (CRA), therefore the study was an investigation into determined town and village green (dTVG) applications. The project also set out to examine whether the sites were earmarked for development in local development plans or subject to planning applications. The full diversity of sites, both approved and rejected, was analysed

    Comparative study of CXC chemokines modulation in brown trout (Salmo trutta) following infection with a bacterial or viral pathogen

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    Acknowledgements We would like to acknowledge Richard Paley, Tom Hill and Georgina Rimmer for their collaboration during brown trout infection challenges in CEFAS-Weymouth biosecurity facilities. Bartolomeo Gorgoglione, Stephen W. Feist and Nick G. H. Taylor were supported by a DEFRA grant (F1198).Peer reviewedPostprin

    Roll strategy efficiency in commodity futures markets

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    Risk Control:Who Cares?

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    Perspectives on the social question : poverty and unemployment in liberal and neoliberal Britain

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    The thesis seeks to ask what we can learn from historical perspectives on poverty and unemployment in the liberal era for an understanding of poverty and unemployment in the neoliberal era. It does this through staging a series of historical interventions with figures and groups in the late-nineteenth and early-twentieth century (1870 to 1939) and then turning to the twenty-first century to look at how poverty and unemployment have been conceptualized and governed. It explores the continuing role of moralizing discourses targeted at the poor and unemployed, variously labelled as the “residuum”, “unemployables”, “habitual loafers”, “shirkers” and “scroungers”. In both the liberal and neoliberal eras, the objective is to explore how these discourses, and various practices of classifying and excluding the poor and unemployed, and seeking to conduct their behaviour, constitute a kind of “illiberal liberalism”. The thesis employs theoretical approaches from Marxist, Foucauldian and history of economic thought literatures to understand this in terms of different forms of “social control”. It finds that moralized judgements of behaviour, character and class significantly affect how poverty and unemployment are thought about, even as structural and economic understandings of these problems advance and become more “scientific”. The first set of perspectives it explores is from late-nineteenth century neoclassical economist William Stanley Jevons and Alfred Marshall. The second set explores the contributions of social reformers Charles Booth, Helen Bosanquet and Hubert Llewellyn Smith. The final set looks at the interwar era and includes the National Unemployed Workers’ Movement and the reading of George Orwell’s The Road to Wigan Pier. The thesis draws from these perspectives to demonstrate the historical resonances of illiberal discourses and practices in the neoliberal workforce era, analysing the way that social control runs through the marketization of employment services and the renewed focus on “character”

    Epidemiological and ecological consequences of virus manipulation of host and vector in plant virus transmission.

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    Many plant viruses are transmitted by insect vectors. Transmission can be described as persistent or non-persistent depending on rates of acquisition, retention, and inoculation of virus. Much experimental evidence has accumulated indicating vectors can prefer to settle and/or feed on infected versus noninfected host plants. For persistent transmission, vector preference can also be conditional, depending on the vector's own infection status. Since viruses can alter host plant quality as a resource for feeding, infection potentially also affects vector population dynamics. Here we use mathematical modelling to develop a theoretical framework addressing the effects of vector preferences for landing, settling and feeding-as well as potential effects of infection on vector population density-on plant virus epidemics. We explore the consequences of preferences that depend on the host (infected or healthy) and vector (viruliferous or nonviruliferous) phenotypes, and how this is affected by the form of transmission, persistent or non-persistent. We show how different components of vector preference have characteristic effects on both the basic reproduction number and the final incidence of disease. We also show how vector preference can induce bistability, in which the virus is able to persist even when it cannot invade from very low densities. Feedbacks between plant infection status, vector population dynamics and virus transmission potentially lead to very complex dynamics, including sustained oscillations. Our work is supported by an interactive interface https://plantdiseasevectorpreference.herokuapp.com/. Our model reiterates the importance of coupling virus infection to vector behaviour, life history and population dynamics to fully understand plant virus epidemics

    The Interaction between the ISM and Star Formation in the Dwarf Starburst Galaxy NGC 4214

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    We present the first interferometric study of the molecular gas in the metal-poor dwarf starburst galaxy NGC 4214. Our map of the 12CO(1-0) emission, obtained at the OVRO millimeter array, reveals an unexpected structural wealth. We detected three regions of molecular emission in the north-west (NW), south-east (SE) and centre of NGC 4214 which are in very different and distinct evolutionary stages (total molecular mass: 5.1 x 10^6 M_sun). These differences are apparent most dramatically when the CO morphologies are compared to optical ground based and HST imaging: massive star formation has not started yet in the NW region; the well-known starburst in the centre is the most evolved and star formation in the SE complex started more recently. We derive a star formation efficiency of 8% for the SE complex. Using high--resolution VLA observations of neutral hydrogen HI and our CO data we generated a total gas column density map for NGC 4214 (HI + H_2). No clear correlation is seen between the peaks of HI, CO and the sites of ongoing star formation. This emphasizes the irregular nature of dwarf galaxies. The HI and CO velocities agree well, so do the H-alpha velocities. In total, we cataloged 14 molecular clumps in NGC 4214. Our results from a virial mass analysis are compatible with a Galactic CO-to-H_2 conversion factor for NGC 4214 (lower than what is usually found in metal-poor dwarf galaxies).Comment: accepted for publication in the AJ (February 2001), full ps file at: ftp://ftp.astro.caltech.edu/users/fw/ngc4214/walter_prep.p

    Humans in the Environment: Plants, Animals and Landscapes in Mesolithic Britain and Ireland

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    The final publication is available at Springer via http://dx.doi.org/10.1007/s10963-018-9116-0Environmental archaeology has historically been central to Mesolithic studies in Britain and Ireland. Whilst processual archaeology was concerned with the economic significance of the environment, post-processual archaeology later rejected economically driven narratives, resulting in a turn away from plant and animal remains. Post-processual narratives focused instead on enigmatic ‘ritual’ items that economic accounts struggled to suitably explain. Processual accounts of landscapes, grounded in economic determinism, were also rejected in favour of explorations of their sociocultural aspects. However, in moving away from plant and animal remains, such accounts lacked the ability to rigorously explore the specificities of particular landscapes and humans actions within them. This paper will bridge this gap by considering how palaeoecological and zooarchaeological analyses can be used to explore human interactions with plants and animals, which were key in developing understandings and relationships that ultimately structured landscapes, influenced past human actions and shaped archaeological assemblages

    Evidence against Wolbachia symbiosis in Loa loa

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    BACKGROUND: The majority of filarial nematode species are host to Wolbachia bacterial endosymbionts, although a few including Acanthocheilonema viteae, Onchocerca flexuosa and Setaria equina have been shown to be free of infection. Comparisons of species with and without symbionts can provide important information on the role of Wolbachia symbiosis in the biology of the nematode hosts and the contribution of the bacteria to the development of disease. Previous studies by electron microscopy and PCR have failed to detect intracellular bacterial infection in Loa loa. Here we use molecular and immunohistological techniques to confirm this finding. METHODS: We have used a combination of PCR amplification of bacterial genes (16S ribosomal DNA [rDNA], ftsZ and Wolbachia surface protein [WSP]) on samples of L. loa adults, third-stage larvae (L3) and microfilariae (mf) and immunohistology on L. loa adults and mf derived from human volunteers to determine the presence or absence of Wolbachia endosymbionts. Samples used in the PCR analysis included 5 adult female worms, 4 adult male worms, 5 mf samples and 2 samples of L3. The quality and purity of nematode DNA was tested by PCR amplification of nematode 5S rDNA and with diagnostic primers from the target species and used to confirm the absence of contamination from Onchocerca sp., Mansonella perstans, M. streptocerca and Wuchereria bancrofti. Immunohistology was carried out by light and electron microscopy on L. loa adults and mf and sections were probed with rabbit antibodies raised to recombinant Brugia malayi Wolbachia WSP. Samples from nematodes known to be infected with Wolbachia (O. volvulus, O. ochengi, Litomosoides sigmodontis and B. malayi) were used as positive controls and A. viteae as a negative control. RESULTS: Single PCR analysis using primer sets for the bacterial genes 16S rDNA, ftsZ, and WSP were negative for all DNA samples from L. loa. Positive PCR reactions were obtained from DNA samples derived from species known to be infected with Wolbachia, which confirmed the suitability of the primers and PCR conditions. The quality and purity of nematode DNA samples was verified by PCR amplification of 5S rDNA and with nematode diagnostic primers. Additional analysis by 'long PCR' failed to produce any further evidence for Wolbachia symbiosis. Immunohistology of L. loa adults and mf confirmed the results of the PCR with no evidence for Wolbachia symbiosis. CONCLUSION: DNA analysis and immunohistology provided no evidence for Wolbachia symbiosis in L. loa
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