Mental health of Indonesian university students: U.K. comparison and relationship between mental health shame and self-compassion.

While the Indonesian higher education has been growing rapidly, poor student mental health including a high level of mental health shame is a cause for concern in Indonesia. This study aimed to evaluate their mental health, shame, and self-compassion. One hundred fifty six participants completed self-report measures regarding mental health problems (depression, anxiety, and stress), mental health shame (negative attitudes, and external, internal, and reflected shame), and self-compassion. Data were first compared with 145 U.K. students, then correlation and regression analyses were performed. Indonesian students showed higher levels of mental health problems, family-related mental health shame, and self-compassion than U.K. students. Each type of mental health problem and mental health shame were positively associated with each other. Self-compassion was negatively associated with mental health problems, but not with mental health shame. Self-compassion was consistently the strongest predictor of mental health problems. Among the mental health shame types, only family external shame predicted the level of depression. Self-compassion training and mental health education for their family are recommended to protect the mental health of university students in Indonesia. (PsycInfo Database Record (c) 2022 APA, all rights reserved

Pets’ impact on people`s well-being in COVID-19: A quantitative study

Introduction: The global coronavirus pandemic and the governmental restrictions to prevent the virus from spreading have generated anxiety, impacting people’s well-being. Former research suggested a positive impact of pets on their owner’s well-being, however little research has been conducted within the context of the COVID-19 pandemic in which isolation measures and restrictions were implemented in many countries. Objective: This cross-sectional study was conducted to investigate the influence of pets on people’s well-being, social connectedness, coronavirus anxiety, and the relationship of pet attachment on well-being during the current COVID-19 pandemic. Methods: Participants (N=72) were opportunistically recruited online across several countries. Data was analyzed using a MANOVA and linear regression. Results: The results indicated that there were no significant differences between pet owners and non-pet owners in terms of well-being, social connectedness, and coronavirus anxiety. Furthermore, a statistically significant relationship between higher pet attachment and greater well-being was not found. Implications: Future research should focus on greater sample sizes and longitudinal data, with a focus on how pet-related interventions may improve well-being

Motivation of UK graduate students in education: Self-compassion moderates pathway from extrinsic motivation to intrinsic motivation

Academic motivation is recognised as a key factor for academic success and wellbeing. Highly motivated students actively engage with academic activities and maintain higher levels of wellbeing. Despite the importance of motivation in education, its relationship with engagement and wellbeing remains to be evaluated. Accordingly, this study explored the relationships between motivation, engagement, self-criticism and selfcompassion among UK education postgraduate students. Of 120 postgraduate students approached, 109 completed three self-report scales regarding those constructs. Correlation, regression and moderation analyses were performed. Intrinsic and extrinsic motivation were positively associated with engagement, whereas amotivation was negatively associated with it. Engagement positively predicted intrinsic motivation. Self-criticism and self-compassion moderated the pathway from extrinsic motivation to intrinsic motivation: higher self-criticism weakened the pathway, while higher selfcompassion strengthened it. Findings suggest the importance of engagement in relation to cultivating intrinsic motivation of education students. Moreover, enhancing selfcompassion and reducing self-criticism can help transfer extrinsic to intrinsic motivation.N/

A Shorter Form of the Work Extrinsic and Intrinsic Motivation Scale: Construction and Factorial Validation

While workplace mental health has attracted attention in many countries, work motivation remains under-researched. Research identified that work motivation is associated with many organisational positive outcomes including workplace mental health. One well-recognised measure is the Work Extrinsic and Intrinsic Motivation Scale (WEIMS). Conceptualised on the Self-Determination Theory, this 18-item scale examines six types of work motivation: Intrinsic Motivation, Integrated Regulation, Identified Regulation, Introjected Regulation, External Regulation, and Amotivation. WEIMS can be too long for busy people at work. Accordingly, we constructed and validated a shorter form of WEIMS (SWEIMS), comprising 12 items that evaluate the same six work motivation types. Data collected from two professional samples were analysed to construct and validate the factorial structure: 155 construction workers (138 males and 17 females, Age 40.28 ± 11.05) and 103 hospitality workers (47 males and 56 females, Age 28.2 ± 8.6 years). Correlation analyses and confirmatory factor analyses were performed. Two items from each type were selected based on the strength of correlations with the target WEIMS subscale. SWEIMS demonstrated adequate internal consistency (α ≧ 0.65), and strong correlations with the original version of WEIMS (r = 0.73) in both samples. SWEIMS confirmatory factor analysis replicated the six-factor model of the original SWEIMS. SWEIMS can be a reliable, valid, and user-friendly alternative to WEIMS

Ethnic Minorities’ Experiences of Cardiac Rehabilitation: A Scoping Review

Cardiac rehabilitation (CR) can improve cardiovascular risk factors, decrease cardiac mortality, and promote healthy lifestyle behaviours. However, services remain underutilized by groups of ethnic minorities. The purpose of the study was to identify patients’ personal CR experiences to identify the differences CR makes towards minorities’ lifestyle. An initial electronic search was performed in 2021 for papers ranging from 2008–2020 across specific databases, including PubMed, EMBASE, APA PsycINFO, CINAHL (Cumulative Index to Nursing and Allied Health Literature), and Medline. Google Scholar was also used to supplement the search process and to identify studies performed within grey literature. A total of 1230 records were screened, of which 40 were assessed for eligibility. The final sample consisted of seven qualitative design studies that were identified for inclusion in this review. Based on patient personal experiences, this review identified that ethnic minorities continue to remain disadvantaged when accessing healthcare interventions, primarily as a result of cultural behaviours, linguistic barriers, socioeconomic status, religious and fatalistic beliefs, and low physician referral rates. More research is needed to elucidate this phenomenon and address these factors faced by ethnic minorities

HER-2 overexpression differentially alters transforming growth factor-β responses in luminal versus mesenchymal human breast cancer cells

INTRODUCTION: Amplification of the HER-2 receptor tyrosine kinase has been implicated in the pathogenesis and aggressive behavior of approximately 25% of invasive human breast cancers. Clinical and experimental evidence suggest that aberrant HER-2 signaling contributes to tumor initiation and disease progression. Transforming growth factor beta (TGF-β) is the dominant factor opposing growth stimulatory factors and early oncogene activation in many tissues, including the mammary gland. Thus, to better understand the mechanisms by which HER-2 overexpression promotes the early stages of breast cancer, we directly assayed the cellular and molecular effects of TGF-β1 on breast cancer cells in the presence or absence of overexpressed HER-2. METHODS: Cell proliferation assays were used to determine the effect of TGF-β on the growth of breast cancer cells with normal or high level expression of HER-2. Affymetrix microarrays combined with Northern and western blot analysis were used to monitor the transcriptional responses to exogenous TGF-β1 in luminal and mesenchymal-like breast cancer cells. The activity of the core TGF-β signaling pathway was assessed using TGF-β1 binding assays, phospho-specific Smad antibodies, immunofluorescent staining of Smad and Smad DNA binding assays. RESULTS: We demonstrate that cells engineered to over-express HER-2 are resistant to the anti-proliferative effect of TGF-β1. HER-2 overexpression profoundly diminishes the transcriptional responses induced by TGF-β in the luminal MCF-7 breast cancer cell line and prevents target gene induction by a novel mechanism that does not involve the abrogation of Smad nuclear accumulation, DNA binding or changes in c-myc repression. Conversely, HER-2 overexpression in the context of the mesenchymal MDA-MB-231 breast cell line potentiated the TGF-β induced pro-invasive and pro-metastatic gene signature. CONCLUSION: HER-2 overexpression promotes the growth and malignancy of mammary epithelial cells, in part, by conferring resistance to the growth inhibitory effects of TGF-β. In contrast, HER-2 and TGF-β signaling pathways can cooperate to promote especially aggressive disease behavior in the context of a highly invasive breast tumor model

Determining crystal structures through crowdsourcing and coursework

We show here that computer game players can build high-quality crystal structures. Introduction of a new feature into the computer game Foldit allows players to build and real-space refine structures into electron density maps. To assess the usefulness of this feature, we held a crystallographic model-building competition between trained crystallographers, undergraduate students, Foldit players and automatic model-building algorithms. After removal of disordered residues, a team of Foldit players achieved the most accurate structure. Analysing the target protein of the competition, YPL067C, uncovered a new family of histidine triad proteins apparently involved in the prevention of amyloid toxicity. From this study, we conclude that crystallographers can utilize crowdsourcing to interpret electron density information and to produce structure solutions of the highest quality

Being and Langauge

Senior Project submitted to The Division of Social Studies of Bard College