6 research outputs found
The implementation of wideband cyclostationary feature detector with receiver constraints
- Publication venue
- 'Institute of Electrical and Electronics Engineers (IEEE)'
- Publication date
- 17/07/2017
- Field of study
Efficient and low complexity optimized feature spectrum sensing with receiver offsets
- Publication venue
- 'Institute of Electrical and Electronics Engineers (IEEE)'
- Publication date
- 11/06/2018
- Field of study
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Global burden of 288 causes of death and life expectancy decomposition in 204 countries and territories and 811 subnational locations, 1990–2021: a systematic analysis for the Global Burden of Disease Study 2021
- Author
- Aali Amirali
- Ababneh Hazim S
- Abate Yohannes Habtegiorgis
- Abbafati Cristiana
- Abbasgholizadeh Rouzbeh
- Abbasi-Kangevari Mohsen
- Abbasian Mohammadreza
- Abbastabar Hedayat
- Abd ElHafeez Samar
- Abd-Elsalam Sherief
- Abdelmasseh Michael
- Abdelwahab Ahmed
- Abdollahi Mohammad
- Abdollahifar Mohammad-Amin
- Abdoun Meriem
- Abdulah Deldar Morad
- Abdullahi Auwal
- Abebe Mesfin
- Abebe Samrawit Shawel
- Abedi Aidin
- Abegaz Kedir Hussein
- Abhilash E S
- Abidi Hassan
- Abiodun Olumide
- Aboagye Richard Gyan
- Abolhassani Hassan
- Abolmaali Meysam
- Abouzid Mohamed
- Aboye Girma Beressa
- Abreu Lucas Guimarães
- Abrha Woldu Aberhe
- Abtahi Dariush
- Abu Rumeileh Samir
- Abu-Gharbieh Eman
- Abu-Rmeileh Niveen ME
- Abu-Zaid Ahmed
- Abualruz Hasan
- Abubakar Bilyaminu
- Aburuz Salahdein
- Accrombessi Manfred Mario Kokou
- Adal Tadele Girum
- Adamu Abdu A
- Addo Isaac Yeboah
- Addolorato Giovanni
- Adebiyi Akindele Olupelumi
- Adekanmbi Victor
- Adepoju Abiola Victor
- Adetunji Charles Oluwaseun
- Adetunji Juliana Bunmi
- Adeyeoluwa Temitayo Esther
- Adeyinka Daniel Adedayo
- Adeyomoye Olorunsola Israel
- Admass Biruk Adie Adie
- Adnani Qorinah Estiningtyas Sakilah
- Adra Saryia
- Afolabi Aanuoluwapo Adeyimika
- Afzal Muhammad Sohail
- Afzal Saira
- Agampodi Suneth Buddhika
- Agasthi Pradyumna
- Aggarwal Manik
- Aghamiri Shahin
- Agide Feleke Doyore
- Agodi Antonella
- Agrawal Anurag
- Agyemang-Duah Williams
- Ahinkorah Bright Opoku
- Ahmad Aqeel
- Ahmad Danish
- Ahmad Firdos
- Ahmad Muayyad M
- Ahmad Sajjad
- Ahmad Shahzaib
- Ahmad Tauseef
- Ahmadi Keivan
- Ahmadzade Amir Mahmoud
- Ahmed Ali
- Ahmed Ayman
- Ahmed Haroon
- Ahmed Luai A
- Ahmed Mehrunnisha Sharif
- Ahmed Meqdad Saleh
- Ahmed Muktar Beshir
- Ahmed Syed Anees
- Ajami Marjan
- Aji Budi
- Akara Essona Matatom
- Akbarialiabad Hossein
- Akinosoglou Karolina
- Akinyemiju Tomi
- Akkaif Mohammed Ahmed
- Akyirem Samuel
- Al Hamad Hanadi
- Al Hasan Syed Mahfuz
- Al-Aly Ziyad
- Al-amer Rasmieh Mustafa
- Al-Azzam Sayer
- Al-Gheethi Adel Ali Saeed
- Al-Hanawi Mohammed Khaled
- Al-Marwani Sabah
- Al-Maweri Sadeq Ali Ali
- Al-Mekhlafi Hesham M
- Al-Omari Basem
- Al-Sabah Salman Khalifah
- Al-Tawfiq Jaffar A
- Al-Worafi Yaser Mohammed
- Alahdab Fares
- Alalalmeh Samer O
- Alalwan Tariq A
- Alam Khurshid
- Alam Manjurul
- Alam Noore
- Alanezi Fahad Mashhour
- Alanzi Turki M
- Albakri Almaza
- Albashtawy Mohammed
- AlBataineh Mohammad T
- Alcalde-Rabanal Jacqueline Elizabeth
- Aldawsari Khalifah A
- Aldhaleei Wafa A
- Aldridge Robert W
- Alema Haileselasie Berhane
- Alemayohu Mulubirhan Assefa
- Alemi Sharifullah
- Alemu Yihun Mulugeta
- Alhabib Khalid F
- Alhalaiqa Fadwa Alhalaiqa Naji
- Ali Abid
- Ali Amjad
- Ali Liaqat
- Ali Mohammed Usman
- Ali Rafat
- Ali Shahid
- Ali Syed Shujait Shujait
- Alicandro Gianfranco
- Alif Sheikh Mohammad
- Alikhani Reyhaneh
- Alimohamadi Yousef
- Aliyi Ahmednur Adem
- Aljasir Mohammad A M
- Aljunid Syed Mohamed
- Alla François
- Allebeck Peter
- Almazan Joseph Uy
- Almidani Louay
- Almidani Omar
- Alomari Mahmoud A
- Alonso Jordi
- Alqahtani Jaber S
- Alqalyoobi Shehabaldin
- Alqutaibi Ahmed Yaseen
- Altaany Zaid
- Altaf Awais
- Altirkawi Khalid A
- Aluh Deborah Oyine
- Alvis-Guzman Nelson
- Alwafi Hassan
- Aly Hany
- Aly Safwat
- Alzoubi Karem H
- Amani Reza
- Amare Azmeraw T
- Amegbor Prince M
- Ameyaw Edward Kwabena
- Amin Tarek Tawfik
- Amindarolzarbi Alireza
- Amiri Sohrab
- Amirzade-Iranaq Mohammad Hosein
- Amu Hubert
- Amugsi Dickson A
- Amusa Ganiyu Adeniyi
- Ancuceanu Robert
- Anderlini Deanna
- Anderson David B
- Andrade Pedro Prata
- Andrei Catalina Liliana
- Andrei Tudorel
- Angus Colin
- Anil Abhishek
- Anil Sneha
- Anoushiravani Amir
- Ansari Hossein
- Ansari-Moghaddam Alireza
- Ansariadi Ansariadi
- Antony Catherine M
- Antriyandarti Ernoiz
- Anvari Davood
- Anvari Saeid
- Anwar Saleha
- Anwar Sumadi Lukman
- Anwer Razique
- Anyasodor Anayochukwu Edward
- Aqeel Muhammad
- Arab Juan Pablo
- Arabloo Jalal
- Arafat Mosab
- Aravkin Aleksandr Y
- Areda Demelash
- Aremu Abdulfatai
- Aremu Olatunde
- Ariffin Hany
- Arkew Mesay
- Armocida Benedetta
- Arndt Michael Benjamin
- Arooj Mahwish
- Artamonov Anton A
- Arulappan Judie
- Aruleba Raphael Taiwo
- Arumugam Ashokan
- Asaad Malke
- Asadi-Lari Mohsen
- Asgedom Akeza Awealom
- Asghari-Jafarabadi Mohammad
- Asghariahmadabad Mona
- Ashraf Muhammad
- Aslani Armin
- Astell-Burt Thomas
- Athar Mohammad
- Athari Seyyed Shamsadin
- Atinafu Bantalem Tilaye Tilaye
- Atlaw Habtamu Wondmagegn
- Atorkey Prince
- Atout Maha Moh'd Wahbi
- Atreya Alok
- Aujayeb Avinash
- Ausloos Marcel
- Avan Abolfazl
- Awedew Atalel Fentahun
- Aweke Amlaku Mulat
- Ayala Quintanilla Beatriz Paulina
- Ayatollahi Haleh
- Ayuso-Mateos Jose L
- Ayyoubzadeh Seyed Mohammad
- Azadnajafabad Sina
- Azevedo Rui M S
- Azzam Ahmed Y
- B Darshan B
- Babu Abraham Samuel
- Badar Muhammad
- Badiye Ashish D
- Baghdadi Soroush
- Bagheri Nasser
- Bagherieh Sara
- Bah Sulaiman
- Bahadorikhalili Saeed
- Bahmanziari Najmeh
- Bai Ruhai
- Baig Atif Amin
- Baker Jennifer L
- Bako Abdulaziz T
- Bakshi Ravleen Kaur
- Balakrishnan Senthilkumar
- Balasubramanian Madhan
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- Barone-Adesi Francesco
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- Barrero Lope H
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- Bello Muhammad Bashir
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- Bensenor Isabela M
- Beran Azizullah
- Berezvai Zombor
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- Berice Betyna N
- Bernstein Robert S
- Bertolacci Gregory J
- Bettencourt Paulo J G
- Beyene Kebede A
- Bhagat Devidas S
- Bhagavathula Akshaya Srikanth
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- Bhatti Jasvinder Singh
- Bhatti Manpreet S
- Bhatti Rajbir
- Bhutta Zulfiqar A
- Bikbov Boris
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- Bisignano Catherine
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- Bjørge Tone
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- Boxe Christopher
- Boyko Edward J
- Brady Oliver J
- Braithwaite Dejana
- Brant Luisa C
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- Breitner Susanne
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- Briko Andrey Nikolaevich
- Briko Nikolay Ivanovich
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- Bulamu Norma B
- Bulto Lemma N
- Buonsenso Danilo
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- Carrero Juan J
- Carugno Andrea
- Carvalheiro Cristina G
- Carvalho Felix
- Carvalho Márcia
- Castaldelli-Maia Joao Mauricio
- Castañeda-Orjuela Carlos A
- Castelpietra Giulio
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- Catapano Alberico L
- Cattaruzza Maria Sofia
- Cederroth Christopher R
- Cegolon Luca
- Cembranel Francieli
- Cenderadewi Muthia
- Cercy Kelly M
- Cerin Ester
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- Chadwick Joshua
- Chahine Yaacoub
- Chakraborty Chiranjib
- Chakraborty Promit Ananyo
- Chan Jeffrey Shi Kai
- Chan Raymond N C
- Chandika Rama Mohan
- Chandrasekar Eeshwar K
- Chang Chin-Kuo
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- Chaurasia Akhilanand
- Chen An-Tian
- Chen Angela W
- Chen Catherine S
- Chen Haowei
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- Chen Simiao
- Cheng Ching-Yu
- Cheng Esther T W
- Cherbuin Nicolas
- Cheru Wondimye Ashenafi
- Chien Ju-Huei
- Chimed-Ochir Odgerel
- Chimoriya Ritesh
- Ching Patrick R
- Chirinos-Caceres Jesus Lorenzo
- Chitheer Abdulaal
- Cho William C S
- Chong Bryan
- Chopra Hitesh
- Choudhari Sonali Gajanan
- Chowdhury Rajiv
- Christopher Devasahayam J
- Chukwu Isaac Sunday
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- Chung Erin
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- Chutiyami Muhammad
- Cindi Zinhle
- Cioffi Iolanda
- Claassens Mareli M
- Claro Rafael M
- Coberly Kaleb
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- Elema Teshome Bekele
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- Elgar Frank J
- Elgendy Islam Y
- ElGohary Ghada Metwally Tawfik
- Elhabashy Hala Rashad
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- Elilo Legesse Tesfaye
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- Elmonem Mohamed A
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- Goleij Pouya
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- Hadi Najah R
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- Hailu Alemayehu
- Haj-Mirzaian Arvin
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- Hamadeh Randah R
- Hameed Sajid
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- Hegazi Omar E
- Heidari Golnaz
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- Hesami Hamed
- Hezam Kamal
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- Hossain Sahadat
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- Hosseinzadeh Mehdi
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- Hsairi Mohamed
- Hsieh Vivian Chia-rong
- Hsu Rebecca L
- Hu Chengxi
- Huang Junjie
- Hultström Michael
- Humayun Ayesha
- Hundie Tsegaye Gebreyes
- Hussain Javid
- Hussain M Azhar
- Hussein Nawfal R
- Hussien Foziya Mohammed
- Huynh Hong-Han
- Hwang Bing-Fang
- Ibitoye Segun Emmanuel
- Ibrahim Khalid S
- Iftikhar Pulwasha Maria
- Ijo Desta
- Ikiroma Adalia I
- Ikuta Kevin S
- Ikwegbue Paul Chukwudi
- Ilesanmi Olayinka Stephen
- Ilic Irena M
- Ilic Milena D
- Imam Mohammad Tarique
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- Indriasih Endang
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- Jadidi-Niaragh Farhad
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- Jafarzadeh Abdollah
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- Janko Mark M
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- Jebai Rime
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- Jeganathan Jayakumar
- Jha Anil K
- Jha Ravi Prakash
- Jiang Heng
- Jin Yingzhao
- Johnson Olatunji
- Jokar Mohammad
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- Tavakoli Oliaee Razieh
- Tavangar Seyed Mohammad
- Taveira Nuno
- Tefera Yibekal Manaye
- Temsah Mohamad-Hani
- Temsah Reem Mohamad Hani
- Teramoto Masayuki
- Tesler Riki
- Teye-Kwadjo Enoch
- Thakur Rishu
- Thangaraju Pugazhenthan
- Thankappan Kavumpurathu Raman
- Tharwat Samar
- Thayakaran Rasiah
- Thomas Nihal
- Thomas Nikhil Kenny
- Thomson Azalea M
- Thrift Amanda G
- Thum Chern Choong Chern
- Thygesen Lau Caspar
- Tian Jing
- Tichopad Ales
- Ticoalu Jansje Henny Vera
- Tillawi Tala
- Tiruye Tenaw Yimer
- Titova Mariya Vladimirovna
- Tonelli Marcello
- Topor-Madry Roman
- Toriola Adetunji T
- Torre Anna E
- Touvier Mathilde
- Tovani-Palone Marcos Roberto
- Tran Jasmine T
- Tran Nghia Minh
- Trico Domenico
- Tromans Samuel Joseph
- Truyen Thien Tan Tri Tai
- Tsatsakis Aristidis
- Tsegay Guesh Mebrahtom
- Tsermpini Evangelia Eirini
- Tumurkhuu Munkhtuya
- Tung Kang
- Tyrovolas Stefanos
- Uddin Sayed Mohammad Nazim
- Udoakang Aniefiok John
- Udoh Arit
- Ullah Atta
- Ullah Irfan
- Ullah Saeed
- Ullah Sana
- Umakanthan Srikanth
- Umeokonkwo Chukwuma David
- Unim Brigid
- Unnikrishnan Bhaskaran
- Unsworth Carolyn Anne
- Upadhyay Era
- Urso Daniele
- Usman Jibrin Sammani
- Vahabi Seyed Mohammad
- Vaithinathan Asokan Govindaraj
- Valizadeh Rohollah
- Van de Velde Sarah M
- Van den Eynde Jef
- Varga Orsolya
- Vart Priya
- Varthya Shoban Babu
- Vasankari Tommi Juhani
- Vasic Milena
- Vaziri Siavash
- Vellingiri Balachandar
- Venketasubramanian Narayanaswamy
- Verghese Nicholas Alexander
- Verma Madhur
- Veroux Massimiliano
- Verras Georgios-Ioannis
- Vervoort Dominique
- Villafañe Jorge Hugo
- Villanueva Gabriela Ines
- Vinayak Manish
- Violante Francesco S
- Viskadourou Maria
- Vladimirov Sergey Konstantinovitch
- Vlassov Vasily
- Vo Bay
- Vollset Stein Emil
- Vongpradith Avina
- Vos Theo
- Vujcic Isidora S
- Vukovic Rade
- Wafa Hatem A
- Waheed Yasir
- Wamai Richard G
- Wang Cong
- Wang Ning
- Wang Shu
- Wang Song
- Wang Yanzhong
- Wang Yuan-Pang
- Waqas Muhammad
- Ward Paul
- Wassie Emebet Gashaw
- Watson Stefanie
- Watson Stephanie Louise Watson
- Weerakoon Kosala Gayan
- Wei Melissa Y
- Weintraub Robert G
- Weiss Daniel J
- Westerman Ronny
- Whisnant Joanna L
- Wiangkham Taweewat
- Wickramasinghe Dakshitha Praneeth
- Wickramasinghe Nuwan Darshana
- Wilandika Angga
- Wilkerson Caroline
- Willeit Peter
- Wilson Shadrach
- Wojewodzic Marcin W
- Woldegebreal Demewoz H
- Wolf Axel Walter
- Wolfe Charles D A
- Wondimagegene Yohannes Addisu
- Wong Yen Jun
- Wongsin Utoomporn
- Wool Eve E
- Wu Ai-Min
- Wu Chenkai
- Wu Felicia
- Wu Xinsheng
- Wu Zenghong
- Xia Juan
- Xiao Hong
- Xie Yang
- Xu Suowen
- Xu Wang-Dong
- Xu Xiaoyue
- Xu Yvonne Yiru
- Yadollahpour Ali
- Yamagishi Kazumasa
- Yang Danting
- Yang Lin
- Yano Yuichiro
- Yao Yao
- Yaribeygi Habib
- Ye Pengpeng
- Yehualashet Sisay Shewasinad
- Yesiltepe Metin
- Yesuf Subah Abderehim
- Yezli Saber
- Yi Siyan
- Yigezu Amanuel
- Yip Paul
- Yismaw Malede Berihun
- Yismaw Yazachew
- Yiğit Arzu
- Yiğit Vahit
- Yon Dong Keon
- Yonemoto Naohiro
- Yoon Seok-Jun
- You Yuyi
- Younis Mustafa Z
- Yousefi Zabihollah
- Yu Chuanhua
- Yu Yong
- Yuh Faith H
- Zadey Siddhesh
- Zadnik Vesna
- Zafari Nima
- Zakham Fathiah
- Zaki Nazar
- Zaman Sojib Bin
- Zamora Nelson
- Zand Ramin
- Zangiabadian Moein
- Zar Heather J
- Zare Iman
- Zarrintan Armin
- Zeariya Mohammed G M
- Zeinali Zahra
- Zhang Haijun
- Zhang Jianrong
- Zhang Jingya
- Zhang Liqun
- Zhang Yunquan
- Zhang Zhi-Jiang
- Zhao Hanqing
- Zhong Chenwen
- Zhou Juexiao
- Zhu Bin
- Zhu Lei
- Ziafati Makan
- Zielińska Magdalena
- Zitoun Osama A
- Zoladl Mohammad
- Zou Zhiyong
- Zuhlke Liesl J
- Zumla Alimuddin
- Zweck Elric
- Zyoud Samer H
- Ärnlöv Johan
- Šekerija Mario
- Publication venue
- Elsevier
- Publication date
- 01/01/2024
- Field of study
BACKGROUND Regular, detailed reporting on population health by underlying cause of death is fundamental for public health decision making. Cause-specific estimates of mortality and the subsequent effects on life expectancy worldwide are valuable metrics to gauge progress in reducing mortality rates. These estimates are particularly important following large-scale mortality spikes, such as the COVID-19 pandemic. When systematically analysed, mortality rates and life expectancy allow comparisons of the consequences of causes of death globally and over time, providing a nuanced understanding of the effect of these causes on global populations. METHODS The Global Burden of Diseases, Injuries, and Risk Factors Study (GBD) 2021 cause-of-death analysis estimated mortality and years of life lost (YLLs) from 288 causes of death by age-sex-location-year in 204 countries and territories and 811 subnational locations for each year from 1990 until 2021. The analysis used 56 604 data sources, including data from vital registration and verbal autopsy as well as surveys, censuses, surveillance systems, and cancer registries, among others. As with previous GBD rounds, cause-specific death rates for most causes were estimated using the Cause of Death Ensemble model-a modelling tool developed for GBD to assess the out-of-sample predictive validity of different statistical models and covariate permutations and combine those results to produce cause-specific mortality estimates-with alternative strategies adapted to model causes with insufficient data, substantial changes in reporting over the study period, or unusual epidemiology. YLLs were computed as the product of the number of deaths for each cause-age-sex-location-year and the standard life expectancy at each age. As part of the modelling process, uncertainty intervals (UIs) were generated using the 2·5th and 97·5th percentiles from a 1000-draw distribution for each metric. We decomposed life expectancy by cause of death, location, and year to show cause-specific effects on life expectancy from 1990 to 2021. We also used the coefficient of variation and the fraction of population affected by 90% of deaths to highlight concentrations of mortality. Findings are reported in counts and age-standardised rates. Methodological improvements for cause-of-death estimates in GBD 2021 include the expansion of under-5-years age group to include four new age groups, enhanced methods to account for stochastic variation of sparse data, and the inclusion of COVID-19 and other pandemic-related mortality-which includes excess mortality associated with the pandemic, excluding COVID-19, lower respiratory infections, measles, malaria, and pertussis. For this analysis, 199 new country-years of vital registration cause-of-death data, 5 country-years of surveillance data, 21 country-years of verbal autopsy data, and 94 country-years of other data types were added to those used in previous GBD rounds. FINDINGS The leading causes of age-standardised deaths globally were the same in 2019 as they were in 1990; in descending order, these were, ischaemic heart disease, stroke, chronic obstructive pulmonary disease, and lower respiratory infections. In 2021, however, COVID-19 replaced stroke as the second-leading age-standardised cause of death, with 94·0 deaths (95% UI 89·2-100·0) per 100 000 population. The COVID-19 pandemic shifted the rankings of the leading five causes, lowering stroke to the third-leading and chronic obstructive pulmonary disease to the fourth-leading position. In 2021, the highest age-standardised death rates from COVID-19 occurred in sub-Saharan Africa (271·0 deaths [250·1-290·7] per 100 000 population) and Latin America and the Caribbean (195·4 deaths [182·1-211·4] per 100 000 population). The lowest age-standardised death rates from COVID-19 were in the high-income super-region (48·1 deaths [47·4-48·8] per 100 000 population) and southeast Asia, east Asia, and Oceania (23·2 deaths [16·3-37·2] per 100 000 population). Globally, life expectancy steadily improved between 1990 and 2019 for 18 of the 22 investigated causes. Decomposition of global and regional life expectancy showed the positive effect that reductions in deaths from enteric infections, lower respiratory infections, stroke, and neonatal deaths, among others have contributed to improved survival over the study period. However, a net reduction of 1·6 years occurred in global life expectancy between 2019 and 2021, primarily due to increased death rates from COVID-19 and other pandemic-related mortality. Life expectancy was highly variable between super-regions over the study period, with southeast Asia, east Asia, and Oceania gaining 8·3 years (6·7-9·9) overall, while having the smallest reduction in life expectancy due to COVID-19 (0·4 years). The largest reduction in life expectancy due to COVID-19 occurred in Latin America and the Caribbean (3·6 years). Additionally, 53 of the 288 causes of death were highly concentrated in locations with less than 50% of the global population as of 2021, and these causes of death became progressively more concentrated since 1990, when only 44 causes showed this pattern. The concentration phenomenon is discussed heuristically with respect to enteric and lower respiratory infections, malaria, HIV/AIDS, neonatal disorders, tuberculosis, and measles. INTERPRETATION Long-standing gains in life expectancy and reductions in many of the leading causes of death have been disrupted by the COVID-19 pandemic, the adverse effects of which were spread unevenly among populations. Despite the pandemic, there has been continued progress in combatting several notable causes of death, leading to improved global life expectancy over the study period. Each of the seven GBD super-regions showed an overall improvement from 1990 and 2021, obscuring the negative effect in the years of the pandemic. Additionally, our findings regarding regional variation in causes of death driving increases in life expectancy hold clear policy utility. Analyses of shifting mortality trends reveal that several causes, once widespread globally, are now increasingly concentrated geographically. These changes in mortality concentration, alongside further investigation of changing risks, interventions, and relevant policy, present an important opportunity to deepen our understanding of mortality-reduction strategies. Examining patterns in mortality concentration might reveal areas where successful public health interventions have been implemented. Translating these successes to locations where certain causes of death remain entrenched can inform policies that work to improve life expectancy for people everywhere. FUNDING Bill & Melinda Gates Foundation
SARS-CoV-2 vaccination modelling for safe surgery to save lives: data from an international prospective cohort study
- Author
- Aamir Junaid
- Abaalkhail Muath
- Ababneh Adnan
- Ababneh Hazim
- Ababneh Laila
- Ababneh Roba
- Abad-Motos Ane
- Abaker Mussab
- Abary Ryan
- Abass Adam
- Abate Emmanuele
- Abayomi Olukayode
- Abazeed Alaa
- Abbad Bader
- Abbadessa Francesco
- Abbadi Osaid
- Abbakar Malaz
- Abbas Ahmed
- Abbas Alzhraa
- Abbas Asad
- Abbas Aya
- Abbas Jihad
- Abbas Manzar
- Abbas Mohammad
- Abbas Omer
- Abbasov Aykhan
- Abbo Olivier
- Abbott Daniel
- Abbott Tom
- Abboud Omar
- Abd Waleed
- Abd-Elkariem Ahmed
- Abd-Elsalam Sherief
- Abdalah Ahmad
- Abdalhadi Alya
- Abdalla Ahmed
- Abdalla Eman
- Abdalla Samir
- Abdalla Shimaa
- Abdalla Siddig
- Abdallah Emne
- Abdallah Ghaida
- Abdallah Lubna
- Abdallah Munir
- Abdallah Murad Al
- Abdallah Rasha
- Abdalnour Hani
- Abdeen Bashar
- Abdeewi Saedah
- Abdeh Louai
- Abdel-Aleem Mahmoud
- Abdel-Elsalam Wafaa
- Abdel-Fattah Areej
- Abdel-Fattah Nour
- Abdel-Hafez Ibrahim
- Abdelaal Abdelrahman
- Abdelaty Ahmed Adel
- Abdelazeem Khaled
- Abdelaziz Areej
- Abdelaziz Mohammed
- Abdelbagi Mohamad
- Abdelbaset Abouelnour
- Abdeldayem Hesham
- Abdelfattah Mahmoud
- Abdelgadir Alwaleed
- Abdelgalel Khaled
- Abdelghafar Moslem
- Abdelhafez Mohammed
- Abdeljalil Abdelkarim
- Abdelkabir Mohammed
- Abdelkareem Mohamed
- Abdelkarem Mohamed
- Abdelkarim Mostafa
- Abdelkhalek Mohamed
- Abdellah Fatima
- Abdelmajeed Ahmed
- Abdelmalik Abubaker
- Abdelmawla Ahmed
- Abdelrahman Abdelrahman
- Abdelrahman Haneen
- Abdelraouf Ali
- Abdelsamed Ahmed
- Abdelwahab Omar
- Abderrazaq Hafni
- Abdissa Desalegn
- Abdo Adnan Sayid
- Abdou Hossam
- Abdou Mostafa
- Abdoun Meriem
- Abdow Mohammad
- Abdrabou Ahmed
- Abdualqader Mahmmoud
- Abdul-Jabar Hani
- Abdul-Mumin Alhassan
- Abdulaal Safaa
- Abdulateef Omar
- Abdulfattah Ammar Yasser
- Abdulkareem Amal
- Abdull Mohammed
- Abdullaev Abakar
- Abdullah Abdullah
- Abdullah Bahiyah
- Abdullah Duha Milad
- Abdullah Muhammad Tariq
- Abdullah Nabila
- Abdullah Saleha
- Abdullah Shahbaz
- Abdullaha Lamess
- Abdullahi Alhassan
- Abdullahi Habiba
- Abdullahi Lawal
- Abdullahi Mohammed Kabir
- Abdullahi Sani
- Abdullahi Yasir Younis
- Abdulmalek Abdulmalek
- Abdulmalik Abdulmuez
- Abdulmohsen Ahmed
- Abdulqawi Nabil
- Abdulrahem Abdullah
- Abdulrahman Mamuda
- Abdulrahman Mohamed
- Abdulrahman Taha
- Abdulsalam Albaraa
- Abdulsalam Fareed
- Abdulsalam Khalifa
- Abdulsalam Moruf
- Abdulwahab Taiceer
- Abdulwahed Eman
- Abdunabi Murad
- Abdur-Rahman Lukman
- Abdurab Ebrahim
- Abdurehman Oumer
- Abdurrazzaaq Abdussemee
- Abdus-Salam Rukiyat
- Abdussalam Hameedat Opeyemi
- Abe Anthonia
- Abe Nobutsugu
- Abe Tatsuro
- Abebe Engida
- Abebe Kirubel
- Abebe Metasebia
- Abebe Nebyou
- Abebrese John Tabiri
- Abed Arsan Abu
- Abed Francisco
- Abed Haneen
- Abed Laith Abu
- Abedalqader Lina
- Abedin Yasmin
- Abel Joel Reuben
- Abel Livingston
- Abel Mary Kathryn
- Abelevich Alexander
- Abella Andrei Cesar
- Abichou Wijden
- Abid Rubaba
- Abiodun Adekunle
- Abiola Olajide
- Abiola Paul
- Abiyere Henry
- Aboalsamh Ghaleb
- Aboazamazem Hajir
- Abodeeb Aya
- Aboelkhel Roger
- Abojeila Farah
- Abosamak Nour Eldin
- Abosnaina Yahya
- Abostate Ahmed
- Abou-Abbass Hussein
- Abou-Khalil Jad
- Abouassi Layth
- Abouassi Majd
- Aboubakr Samar
- Aboubeirah Mohammed
- Abouelazayem Mohamed
- Abouelnagah Galal
- Abouelnagah Yossof
- Aboutaleb Shereen
- Aboutrab Ayham
- Abouzid Amr
- Abozied Hesham
- Abraham Bejoy
- Abrahams Jenevive
- Abramowicz Shelly
- Abrate Alberto
- Abreha Tassew
- Abrha Teklebirhan
- Abu-Arish Hamdoon
- Abu-Eisheh Basil
- Abu-Ishkerih Nizar
- Abu-Ismail Luai
- Abu-Libdeh Tareq
- Abu-Mehsen Marah
- Abu-Zaid Ahmed
- Abualteen Faisal
- Abuawad Carla
- Abubakar Abdullah
- Abubakar Ahmed
- Abubakar Mohammed Kabir
- Abubakr Abubakr
- Abubakr Asmaa
- Abubeih Hossam
- Abud Burçin
- Abudari Hadeel
- Abudher Abdulhafid
- Abuhamour Ehab
- Abuissa Khatab
- Abukhadra Mahmoud
- Abukhalaf Sadi A
- Abukhater Muhammad
- Abulafia Daniel
- Abuleil Amro
- Abulshuwashi Nayrouz Abdullah
- Abumahara Saleh
- Abunawas Huthifa
- Aburahmah Mohammad
- Aburayyan Fatima
- Aburima Sarah
- Abusabeib Abdelrahman
- Abusadah Samer
- Abusalem Marwa
- Abusannoga Malek
- Abushahma Ahmed Omar
- Abutaka Ahmad
- Abutaleb Malak
- Abuzaina Khalil
- Acatrinei Eduard
- Accarino Giulio
- Accorsi Guilherme
- Acharya Hriday
- Acharya Metesh
- Acharya Shivanie
- Achimas-Cadariu Patriciu
- Ackermann Travis
- Acosta Jesus
- Acosta Maria
- Acosta Yancy
- Acosta Úrsula
- Acquaye Jane
- Acra-Tolari Ricardo
- Acuña Gastón
- Adam John
- Adamala Soujanya
- Adamina Michel
- Adamoli Laura
- Adams Katie
- Adapa Akshath
- Addas Bassam
- Adebajo Emmanuel
- Adebanjo Ademola
- Adebara Idowu
- Adebayo Olaolu
- Adebayo Sikiru A
- Adeboyejo Oluwaseun
- Adegbola Samuel
- Adel Dina
- Adelaja Aderinsola
- Adeleye Amos
- Adeli Seyyed Hassan
- Adem Ephrem
- Ademola Samuel
- Ademuyiwa Adesoji
- Adeniran Abimbola
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- Adeniyi Adebayo
- Adenwalla Mehjabeen
- Aderogba Adeleke Akeem
- Aderounmu Adewale
- Adesanya Opeoluwa
- Adesina Oluwaseyi
- Adesola Muideen
- Adeyemo Olabisi
- Adeyeye Ademola
- Adham Ibrahim
- Adi Hussam
- Adiamah Alfred
- Adikaibe Valentine
- Adil Md Tanveer
- Adisa Adewale
- Aditianingsih Dita
- Adjeso Theophilus
- Adlan Alsafe
- Adler Tina
- Admasu Azarias
- Adofo-Asamoah Yvonne
- Adrees Mohammed
- Adrianzén Marcos
- Adu-Aryee Nii Armah
- Aduse-Poku Maame
- Advani Rajeev
- Adze Joel
- Aeed Majed
- Afaque Syed Nayyar
- Afifi Amgad
- Afifi Eman
- Afifi Nermeen
- Afify Abdelrahman
- Afolabi Abdulrahman O
- Afolabi Akinwale
- Afolabi Bosede
- Afshar Salim
- Aftab Raiyyan
- Afuwape Oludolapo
- Afzal Ameer
- Afzal Maimoona
- Afzal Mohamed
- Afzal Muhammad Farooq
- Afzal Sadia
- Agalianos Christos
- Agapov Mikhail
- Agarwal Anjoo
- Agarwal Arnav
- Agarwal Gaurav
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- Agarwal Varun
- Agastra Ervis
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- Agbaje Ademola
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- Ageeli Mohammed
- Aggarwal Gaurav
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- Aghababyan Kristina
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- Aghamaliyev Ughur
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- Agrawal Tulika
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- Aguado Héctor J
- Aguayo Omar
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- Ahmed Waqas
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- Ahmedin Mahlet
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- Ahtash Abdurahman
- Aidarov Askar
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- Aimé Adeline
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- Akbas Ahmet
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- Akhtar Fahad
- Akhtar Muhammad Adeel
- Akhtar Muhammad Shaheer
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- Akiely Jehad
- Akililu Yemisirach Bizuneh
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- Aklilu Abenezer Tirsit
- Akmercan Ahmet
- Akpla Marcellin
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- Akram Shahzad
- Aktaa Nazeeh Al
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- Aktimur Yunus Emre
- Akulaev Anton
- Akyol Cihangir
- Akça Oktay
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- Al-Atiyah Hussam
- Al-Azzawi Marwa
- Al-Badawi Ismail
- Al-Balas Hasan
- Al-Dabaa Tawfik
- Al-Darabah Ali
- Al-Dhaheri Awsan
- Al-Dolat Wedad
- Al-Embideen Somya
- Al-Eryani Fatima
- Al-Garadi Abdulrahman Faisal
- Al-Gilani Maha
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- Al-Houssami Salma
- Al-Howthi Mohammed
- Al-Isawi Ali
- Al-Jadaan Mohammad
- Al-Jarrah Amar
- Al-Jarrah Hothaifa
- Al-Jarrah Salsabeel
- Al-Kasaji Farah
- Al-Khaddar Ziad
- Al-Latayfeh Motasem
- Al-Madhrahi Ahmed
- Al-Maghrabi Sanabel
- Al-Mahdi Shehab
- Al-Mahmeed Husain
- Al-Manaseer Balqees Mahmoud
- Al-Mandeel Hazem
- Al-Maqtari Sahar
- Al-Masari Hayder
- Al-Masood Mohammed
- Al-Masri Mahmoud
- Al-Maswari Sakhr Abdulhakeem
- Al-Mohammad Abdulrahman
- Al-Mouakeh Ahmad
- Al-Mujaini Abdullah
- Al-Mukhaizeem Youssef
- Al-Naggar Hamza
- Al-Najjar Dania
- Al-Najjar Hani
- Al-Nawas Bilal
- Al-Oqabi Ayman
- Al-Oribi Saeid
- Al-Osta Malk
- Al-Othman Hadeel
- Al-Qannas Mohammad
- Al-Qannass Ali
- Al-Qattan Mohammad
- Al-Qurashi Qusay
- Al-Radi Osman
- Al-Raimi Ibrahim
- Al-Ramli Wisam
- Al-Rashdi Aya
- Al-Saadi Nina
- Al-Saban Rafat
- Al-Sabbagh Yusra
- Al-Shaiji Tariq
- Al-Shaikh Ghadeer
- Al-Shammakh Sonds
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- Vokshi Ismail
- Volkova Olga
- Volpe Gustavo Jardim
- Volpin Enrico
- Volpin Francesco
- von Ehrlich-Treuenstätt Viktor H
- von Renesse Janusz
- von Rundstedt Friedrich-Carl
- Voonna Murali Krishna
- Voppuru Saiesh Reddy
- Vora Sameer
- Voros Peter
- Vosoughi Fardis
- Vossler Kristen
- Vounckx Manon
- Vourganti Srinivas
- Vovola Fernanda
- Vozian Marin
- Vrakopoulou Gavriella Zoi
- Vömel Jacob
- Wadei Hajr Al
- Yahya Zakaria Al
- Zahran Mohammed
- Zahrani Attiya Al
- Zahrani Turki Ai
- Zaid Muna
- Zein Zeina Al
- Álvarez Sofia
- Älgå Andreas
- Publication venue
- 'Oxford University Press (OUP)'
- Publication date
- 01/01/2021
- Field of study
Background: Preoperative SARS-CoV-2 vaccination could support safer elective surgery. Vaccine numbers are limited so this study aimed to inform their prioritization by modelling.
Methods: The primary outcome was the number needed to vaccinate (NNV) to prevent one COVID-19-related death in 1 year. NNVs were based on postoperative SARS-CoV-2 rates and mortality in an international cohort study (surgical patients), and community SARS-CoV-2 incidence and case fatality data (general population). NNV estimates were stratified by age (18-49, 50-69, 70 or more years) and type of surgery. Best- and worst-case scenarios were used to describe uncertainty.
Results: NNVs were more favourable in surgical patients than the general population. The most favourable NNVs were in patients aged 70 years or more needing cancer surgery (351; best case 196, worst case 816) or non-cancer surgery (733; best case 407, worst case 1664). Both exceeded the NNV in the general population (1840; best case 1196, worst case 3066). NNVs for surgical patients remained favourable at a range of SARS-CoV-2 incidence rates in sensitivity analysis modelling. Globally, prioritizing preoperative vaccination of patients needing elective surgery ahead of the general population could prevent an additional 58 687 (best case 115 007, worst case 20 177) COVID-19-related deaths in 1 year.
Conclusion: As global roll out of SARS-CoV-2 vaccination proceeds, patients needing elective surgery should be prioritized ahead of the general population
Global burden of 288 causes of death and life expectancy decomposition in 204 countries and territories and 811 subnational locations, 1990–2021: a systematic analysis for the Global Burden of Disease Study 2021
- Author
- Aali Amirali
- Ababneh Hazim S
- Abate Yohannes Habtegiorgis
- Abbafati Cristiana
- Abbasgholizadeh Rouzbeh
- Abbasi-Kangevari Mohsen
- Abbasian Mohammadreza
- Abbastabar Hedayat
- Abd ElHafeez Samar
- Abd-Elsalam Sherief
- Abdelmasseh Michael
- Abdelwahab Ahmed
- Abdollahi Mohammad
- Abdollahifar Mohammad-Amin
- Abdoun Meriem
- Abdulah Deldar Morad
- Abdullahi Auwal
- Abebe Mesfin
- Abebe Samrawit Shawel
- Abedi Aidin
- Abegaz Kedir Hussein
- Abhilash E S
- Abidi Hassan
- Abiodun Olumide
- Aboagye Richard Gyan
- Abolhassani Hassan
- Abolmaali Meysam
- Abouzid Mohamed
- Aboye Girma Beressa
- Abreu Lucas Guimarães
- Abrha Woldu Aberhe
- Abtahi Dariush
- Abu Rumeileh Samir
- Abu-Gharbieh Eman
- Abu-Rmeileh Niveen ME
- Abu-Zaid Ahmed
- Abualruz Hasan
- Abubakar Bilyaminu
- Aburuz Salahdein
- Accrombessi Manfred Mario Kokou
- Adal Tadele Girum
- Adamu Abdu A
- Addo Isaac Yeboah
- Addolorato Giovanni
- Adebiyi Akindele Olupelumi
- Adekanmbi Victor
- Adepoju Abiola Victor
- Adetunji Charles Oluwaseun
- Adetunji Juliana Bunmi
- Adeyeoluwa Temitayo Esther
- Adeyinka Daniel Adedayo
- Adeyomoye Olorunsola Israel
- Admass Biruk Adie Adie
- Adnani Qorinah Estiningtyas Sakilah
- Adra Saryia
- Afolabi Aanuoluwapo Adeyimika
- Afzal Muhammad Sohail
- Afzal Saira
- Agampodi Suneth Buddhika
- Agasthi Pradyumna
- Aggarwal Manik
- Aghamiri Shahin
- Agide Feleke Doyore
- Agodi Antonella
- Agrawal Anurag
- Agyemang-Duah Williams
- Ahinkorah Bright Opoku
- Ahmad Aqeel
- Ahmad Danish
- Ahmad Firdos
- Ahmad Muayyad M
- Ahmad Sajjad
- Ahmad Shahzaib
- Ahmad Tauseef
- Ahmadi Keivan
- Ahmadzade Amir Mahmoud
- Ahmed Ali
- Ahmed Ayman
- Ahmed Haroon
- Ahmed Luai A
- Ahmed Mehrunnisha Sharif
- Ahmed Meqdad Saleh
- Ahmed Muktar Beshir
- Ahmed Syed Anees
- Ajami Marjan
- Aji Budi
- Akara Essona Matatom
- Akbarialiabad Hossein
- Akinosoglou Karolina
- Akinyemiju Tomi
- Akkaif Mohammed Ahmed
- Akyirem Samuel
- Al Hamad Hanadi
- Al Hasan Syed Mahfuz
- Al-Aly Ziyad
- Al-amer Rasmieh Mustafa
- Al-Azzam Sayer
- Al-Gheethi Adel Ali Saeed
- Al-Hanawi Mohammed Khaled
- Al-Marwani Sabah
- Al-Maweri Sadeq Ali Ali
- Al-Mekhlafi Hesham M
- Al-Omari Basem
- Al-Sabah Salman Khalifah
- Al-Tawfiq Jaffar A
- Al-Worafi Yaser Mohammed
- Alahdab Fares
- Alalalmeh Samer O
- Alalwan Tariq A
- Alam Khurshid
- Alam Manjurul
- Alam Noore
- Alanezi Fahad Mashhour
- Alanzi Turki M
- Albakri Almaza
- Albashtawy Mohammed
- AlBataineh Mohammad T
- Alcalde-Rabanal Jacqueline Elizabeth
- Aldawsari Khalifah A
- Aldhaleei Wafa A
- Aldridge Robert W
- Alema Haileselasie Berhane
- Alemayohu Mulubirhan Assefa
- Alemi Sharifullah
- Alemu Yihun Mulugeta
- Alhabib Khalid F
- Alhalaiqa Fadwa Alhalaiqa Naji
- Ali Abid
- Ali Amjad
- Ali Liaqat
- Ali Mohammed Usman
- Ali Rafat
- Ali Shahid
- Ali Syed Shujait Shujait
- Alicandro Gianfranco
- Alif Sheikh Mohammad
- Alikhani Reyhaneh
- Alimohamadi Yousef
- Aliyi Ahmednur Adem
- Aljasir Mohammad A M
- Aljunid Syed Mohamed
- Alla François
- Allebeck Peter
- Almazan Joseph Uy
- Almidani Louay
- Almidani Omar
- Alomari Mahmoud A
- Alonso Jordi
- Alqahtani Jaber S
- Alqalyoobi Shehabaldin
- Alqutaibi Ahmed Yaseen
- Altaany Zaid
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- Amugsi Dickson A
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- Anderson David B
- Andrade Pedro Prata
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- Angus Colin
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- Arab Juan Pablo
- Arabloo Jalal
- Arafat Mosab
- Aravkin Aleksandr Y
- Areda Demelash
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- Aremu Olatunde
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- Armocida Benedetta
- Arndt Michael Benjamin
- Arooj Mahwish
- Artamonov Anton A
- Arulappan Judie
- Aruleba Raphael Taiwo
- Arumugam Ashokan
- Asaad Malke
- Asadi-Lari Mohsen
- Asgedom Akeza Awealom
- Asghari-Jafarabadi Mohammad
- Asghariahmadabad Mona
- Ashraf Muhammad
- Aslani Armin
- Astell-Burt Thomas
- Athar Mohammad
- Athari Seyyed Shamsadin
- Atinafu Bantalem Tilaye Tilaye
- Atlaw Habtamu Wondmagegn
- Atorkey Prince
- Atout Maha Moh'd Wahbi
- Atreya Alok
- Aujayeb Avinash
- Ausloos Marcel
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- Banik Palash Chandra
- Bansal Hansi
- Bansal Kannu
- Barbic Franca
- Barchitta Martina
- Bardhan Mainak
- Bardideh Erfan
- Barker-Collo Suzanne Lyn
- Barone-Adesi Francesco
- Barqawi Hiba Jawdat
- Barrero Lope H
- Barrow Amadou
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- Barua Lingkan
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- Bjørge Tone
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- Boampong Mary Sefa
- Bobirca Anca Vasilica
- Bodolica Virginia
- Bodunrin Aadam Olalekan
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- Bogale Kassawmar Angaw
- Bohlouli Somayeh
- Bolarinwa Obasanjo Afolabi
- Boloor Archith
- Bonakdar Hashemi Milad
- Bonny Aime
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- Bärnighausen Till Winfried
- Béjot Yannick
- Caetano dos Santos Florentino Luciano
- Calina Daniela
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- Cao Chao
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- Carr Sinclair
- Carreras Giulia
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- Carugno Andrea
- Carvalheiro Cristina G
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- Castaldelli-Maia Joao Mauricio
- Castañeda-Orjuela Carlos A
- Castelpietra Giulio
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- Cenderadewi Muthia
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- Cerin Ester
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- Chahine Yaacoub
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- Chandika Rama Mohan
- Chandrasekar Eeshwar K
- Chang Chin-Kuo
- Chang Jung-Chen
- Chanie Gashaw Sisay
- Charalampous Periklis
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- Chaturvedi Pankaj
- Chatzimavridou-Grigoriadou Victoria
- Chaurasia Akhilanand
- Chen An-Tian
- Chen Angela W
- Chen Catherine S
- Chen Haowei
- Chen Meng Xuan
- Chen Simiao
- Cheng Ching-Yu
- Cheng Esther T W
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- Cheru Wondimye Ashenafi
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- Chimed-Ochir Odgerel
- Chimoriya Ritesh
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- Chowdhury Rajiv
- Christopher Devasahayam J
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- Dominguez Regina-Mae Villanueva
- Dong Wanyue
- Dongarwar Deepa
- Dorostkar Fariba
- Dorsey E Ray
- dos Santos Wendel Mombaque
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- E'mar Abdel Rahman
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- Ebrahimi Alireza
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- Edvardsson Kristina
- Efendi Defi
- Efendi Ferry
- Effendi Diyan Ermawan
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- Eini Ebrahim
- Ekholuenetale Michael
- Ekundayo Temitope Cyrus
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- Ghashghaee Ahmad
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- Ghimire Ajnish
- Ghoba Sama
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- Gholamian Asadollah
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- Guimarães Rafael Alves
- Gulati Snigdha
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- Gupta Bhawna
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- Gupta Mohak
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- Gurmessa Lami
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- Hasani Hamidreza
- Hasanian Mohammad
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- Herrera-Serna Brenda Yuliana
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- Hezam Kamal
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- Hiraike Yuta
- Holla Ramesh
- Horita Nobuyuki
- Hossain Md Mahbub
- Hossain Sahadat
- Hosseini Mohammad-Salar
- Hosseinzadeh Adli Ahmad
- Hosseinzadeh Hassan
- Hosseinzadeh Mehdi
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- Hostiuc Sorin
- Hsairi Mohamed
- Hsieh Vivian Chia-rong
- Hsu Rebecca L
- Hu Chengxi
- Huang Junjie
- Hultström Michael
- Humayun Ayesha
- Hundie Tsegaye Gebreyes
- Hussain Javid
- Hussain M Azhar
- Hussein Nawfal R
- Hussien Foziya Mohammed
- Huynh Hong-Han
- Hwang Bing-Fang
- Ibitoye Segun Emmanuel
- Ibrahim Khalid S
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- Spearman Sandra
- Sreeramareddy Chandrashekhar T
- Srivastava Vijay Kumar
- Stanaway Jeffrey D
- Stanikzai Muhammad Haroon
- Stark Benjamin A
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- Starodubova Antonina V
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- Tadakamadla Santosh Kumar
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- Thangaraju Pugazhenthan
- Thankappan Kavumpurathu Raman
- Tharwat Samar
- Thayakaran Rasiah
- Thomas Nihal
- Thomas Nikhil Kenny
- Thomson Azalea M
- Thrift Amanda G
- Thum Chern Choong Chern
- Thygesen Lau Caspar
- Tian Jing
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- Vaithinathan Asokan Govindaraj
- Valizadeh Rohollah
- Van de Velde Sarah M
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- Vujcic Isidora S
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- Watson Stefanie
- Watson Stephanie Louise Watson
- Weerakoon Kosala Gayan
- Wei Melissa Y
- Weintraub Robert G
- Weiss Daniel J
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- Wilandika Angga
- Wilkerson Caroline
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- Wojewodzic Marcin W
- Woldegebreal Demewoz H
- Wolf Axel Walter
- Wolfe Charles D A
- Wondimagegene Yohannes Addisu
- Wong Yen Jun
- Wongsin Utoomporn
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- Xia Juan
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- Xu Yvonne Yiru
- Yadollahpour Ali
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- Yang Danting
- Yang Lin
- Yano Yuichiro
- Yao Yao
- Yaribeygi Habib
- Ye Pengpeng
- Yehualashet Sisay Shewasinad
- Yesiltepe Metin
- Yesuf Subah Abderehim
- Yezli Saber
- Yi Siyan
- Yigezu Amanuel
- Yip Paul
- Yismaw Malede Berihun
- Yismaw Yazachew
- Yiğit Arzu
- Yiğit Vahit
- Yon Dong Keon
- Yonemoto Naohiro
- Yoon Seok-Jun
- You Yuyi
- Younis Mustafa Z
- Yousefi Zabihollah
- Yu Chuanhua
- Yu Yong
- Yuh Faith H
- Zadey Siddhesh
- Zadnik Vesna
- Zafari Nima
- Zakham Fathiah
- Zaki Nazar
- Zaman Sojib Bin
- Zamora Nelson
- Zand Ramin
- Zangiabadian Moein
- Zar Heather J
- Zare Iman
- Zarrintan Armin
- Zeariya Mohammed G M
- Zeinali Zahra
- Zhang Haijun
- Zhang Jianrong
- Zhang Jingya
- Zhang Liqun
- Zhang Yunquan
- Zhang Zhi-Jiang
- Zhao Hanqing
- Zhong Chenwen
- Zhou Juexiao
- Zhu Bin
- Zhu Lei
- Ziafati Makan
- Zielińska Magdalena
- Zitoun Osama A
- Zoladl Mohammad
- Zou Zhiyong
- Zuhlke Liesl J
- Zumla Alimuddin
- Zweck Elric
- Zyoud Samer H
- Ärnlöv Johan
- Šekerija Mario
- Publication venue
- Elsevier
- Publication date
- 01/04/2024
- Field of study
BackgroundRegular, detailed reporting on population health by underlying cause of death is fundamental for public health decision making. Cause-specific estimates of mortality and the subsequent effects on life expectancy worldwide are valuable metrics to gauge progress in reducing mortality rates. These estimates are particularly important following large-scale mortality spikes, such as the COVID-19 pandemic. When systematically analysed, mortality rates and life expectancy allow comparisons of the consequences of causes of death globally and over time, providing a nuanced understanding of the effect of these causes on global populations.MethodsThe Global Burden of Diseases, Injuries, and Risk Factors Study (GBD) 2021 cause-of-death analysis estimated mortality and years of life lost (YLLs) from 288 causes of death by age-sex-location-year in 204 countries and territories and 811 subnational locations for each year from 1990 until 2021. The analysis used 56 604 data sources, including data from vital registration and verbal autopsy as well as surveys, censuses, surveillance systems, and cancer registries, among others. As with previous GBD rounds, cause-specific death rates for most causes were estimated using the Cause of Death Ensemble model—a modelling tool developed for GBD to assess the out-of-sample predictive validity of different statistical models and covariate permutations and combine those results to produce cause-specific mortality estimates—with alternative strategies adapted to model causes with insufficient data, substantial changes in reporting over the study period, or unusual epidemiology. YLLs were computed as the product of the number of deaths for each cause-age-sex-location-year and the standard life expectancy at each age. As part of the modelling process, uncertainty intervals (UIs) were generated using the 2·5th and 97·5th percentiles from a 1000-draw distribution for each metric. We decomposed life expectancy by cause of death, location, and year to show cause-specific effects on life expectancy from 1990 to 2021. We also used the coefficient of variation and the fraction of population affected by 90% of deaths to highlight concentrations of mortality. Findings are reported in counts and age-standardised rates. Methodological improvements for cause-of-death estimates in GBD 2021 include the expansion of under-5-years age group to include four new age groups, enhanced methods to account for stochastic variation of sparse data, and the inclusion of COVID-19 and other pandemic-related mortality—which includes excess mortality associated with the pandemic, excluding COVID-19, lower respiratory infections, measles, malaria, and pertussis. For this analysis, 199 new country-years of vital registration cause-of-death data, 5 country-years of surveillance data, 21 country-years of verbal autopsy data, and 94 country-years of other data types were added to those used in previous GBD rounds.FindingsThe leading causes of age-standardised deaths globally were the same in 2019 as they were in 1990; in descending order, these were, ischaemic heart disease, stroke, chronic obstructive pulmonary disease, and lower respiratory infections. In 2021, however, COVID-19 replaced stroke as the second-leading age-standardised cause of death, with 94·0 deaths (95% UI 89·2–100·0) per 100 000 population. The COVID-19 pandemic shifted the rankings of the leading five causes, lowering stroke to the third-leading and chronic obstructive pulmonary disease to the fourth-leading position. In 2021, the highest age-standardised death rates from COVID-19 occurred in sub-Saharan Africa (271·0 deaths [250·1–290·7] per 100 000 population) and Latin America and the Caribbean (195·4 deaths [182·1–211·4] per 100 000 population). The lowest age-standardised death rates from COVID-19 were in the high-income super-region (48·1 deaths [47·4–48·8] per 100 000 population) and southeast Asia, east Asia, and Oceania (23·2 deaths [16·3–37·2] per 100 000 population). Globally, life expectancy steadily improved between 1990 and 2019 for 18 of the 22 investigated causes. Decomposition of global and regional life expectancy showed the positive effect that reductions in deaths from enteric infections, lower respiratory infections, stroke, and neonatal deaths, among others have contributed to improved survival over the study period. However, a net reduction of 1·6 years occurred in global life expectancy between 2019 and 2021, primarily due to increased death rates from COVID-19 and other pandemic-related mortality. Life expectancy was highly variable between super-regions over the study period, with southeast Asia, east Asia, and Oceania gaining 8·3 years (6·7–9·9) overall, while having the smallest reduction in life expectancy due to COVID-19 (0·4 years). The largest reduction in life expectancy due to COVID-19 occurred in Latin America and the Caribbean (3·6 years). Additionally, 53 of the 288 causes of death were highly concentrated in locations with less than 50% of the global population as of 2021, and these causes of death became progressively more concentrated since 1990, when only 44 causes showed this pattern. The concentration phenomenon is discussed heuristically with respect to enteric and lower respiratory infections, malaria, HIV/AIDS, neonatal disorders, tuberculosis, and measles.InterpretationLong-standing gains in life expectancy and reductions in many of the leading causes of death have been disrupted by the COVID-19 pandemic, the adverse effects of which were spread unevenly among populations. Despite the pandemic, there has been continued progress in combatting several notable causes of death, leading to improved global life expectancy over the study period. Each of the seven GBD super-regions showed an overall improvement from 1990 and 2021, obscuring the negative effect in the years of the pandemic. Additionally, our findings regarding regional variation in causes of death driving increases in life expectancy hold clear policy utility. Analyses of shifting mortality trends reveal that several causes, once widespread globally, are now increasingly concentrated geographically. These changes in mortality concentration, alongside further investigation of changing risks, interventions, and relevant policy, present an important opportunity to deepen our understanding of mortality-reduction strategies. Examining patterns in mortality concentration might reveal areas where successful public health interventions have been implemented. Translating these successes to locations where certain causes of death remain entrenched can inform policies that work to improve life expectancy for people everywhere
Characteristics and outcomes of COVID-19 patients admitted to hospital with and without respiratory symptoms
- Author
- Abbas Syed Ali
- Abdalasalam Sabriya
- Abdalhadi Alaa Abdalfattah
- Abdalla Fadlalla Asgad Osman
- Abdalla Naana Reyam
- Abdalla Walaa
- Abdalrheem Almthani Hamza
- Abdalsalam Ashraf
- Abdeewi Saedah
- Abdelgaum Esraa Hassan
- Abdelghafar Yomna Ali
- Abdelhalim Mohamed
- Abdelkabir Mohammed
- Abdelrahman Mohammedahmed Manahil Omer
- Abdelrahman Israa
- Abdelrhman Abdallahrs Asia Atif
- Abdukahil Sheryl Ann
- Abdulbaqi Lamees Adil
- Abdulhamid Salaheddin
- Abdulhamid Widyan
- Abdulkadir Nurul Najmee
- Abdullah Duha Milad
- Abdulwahed Eman
- Abdunabi Rawad
- Abe Ryuzo
- Abebrese Franklina Korkor
- Abel Laurent
- Abodina Ahmed Mohammed
- Abrous Amal
- Absil Lara
- Abu Salem Talat Ahmed
- Abusalama Abdurraouf
- Abuzaid Tareg Abdallah
- Acharya Subhash
- Acker Andrew
- Adam Elisabeth
- Adem Safia
- Ademnou Manuella
- Adewhajah Francisca
- Adrião Diana
- Ads Alaa Mohamed
- Adusei Amos Amoako
- Afum-Adjei Awuah Anthony
- Agbogbatey Melvin
- Ahmed Khalil Reham Abdelhamid
- Ahmed Mohamed Abdelaziz Ali Mostafa
- Ahmed Aya Mustafa
- Ahmed Musaab Mohammed
- Ahmed Shakeel
- Ainscough Kate
- Airlangga Eka
- Aisa Tharwat
- Aisha Ali
- Aisha Bugila
- Akimoto Takako
- Akmal Ernita
- Akwani Chika
- Al Ageel Saleh
- Al Qasim Eman
- Al-Aquily Mohammed
- Al-dabbous Tala
- Al-Fares Abdulrahman
- Al-Saba'a Yousef
- Alajeeli Ahmed
- Alali Ahmed
- Alalqam Razi
- Alameen Aliya Mohammed
- Alaraji Zainab Ahmed
- Alaraji Zinah A.
- Albakry Khalid
- Albatni Safa
- Alberti Angela
- Aldabbourosama Osama
- Aldhalia Amer
- Aldoukali Abdulkarim
- Alegesan Senthilkumar
- Alessi Marta
- Alex Beatrice
- Alexandre Kévin
- Alflite Asil
- Alfoudri Huda
- Alhadad Qamrah
- Alhaddad Hoda Salem
- Alhouri Ahmad Nabil
- Alhouri Hasan
- Ali Mohammed Abdelmalek Awad
- Ali Adam
- Ali Imran
- Ali Syed Muneeb
- Alidjnou Kazali Enagnon
- Aljadi Mahmoud
- Aljamal Sarah
- Alkahlout Mohammed
- Alkaseek Akram
- Alkhafajee Qabas
- Allavena Clotilde
- Allou Nathalie
- Almasri Lana
- Almjersah Abdulrahman
- Alqandouz Raja Ahmed
- Alrfaea Walaa
- Alrifaee Moayad
- Alsaadi Rawan
- Alshareea Entisar
- Alshenawy Eslam
- Altaf Aneela
- Alves João
- Alves João Melo
- Alves Rita
- Alyasiri Mohammed Saleh
- Amaral Maria
- Amer Amro Essam
- Amira Nur
- Amuasi John
- Andini Roberto
- Andrejak Claire
- Angheben Andrea
- Angoulvant François
- Ankrah Sophia
- Ansari Muhammad Imran
- Ansart Séverine
- Anthonidass Sivanesen
- Antonelli Massimo
- Antunes de Brito Carlos Alexandre
- Apriyana Ardiyan
- Arabi Yaseen
- Aragao Irene
- Arancibia Francisco
- Araujo Carolline
- Arcadipane Antonio
- Archambault Patrick
- Arenz Lukas
- Argin G.
- Arlet Jean-Benoît
- Arnold-Day Christel
- Arora Lovkesh
- Arora Rakesh
- Artaud-Macari Elise
- Aryal Diptesh
- Ascofare Oumou Maiga
- Asensio Angel
- Ashley Elizabeth A.
- Ashraf Muhammad
- Ashraf Muhammad Sheharyar
- Asiedu-Bekoe Franklin
- Asif Namra
- Asim Mohammad
- Assi Grace
- Assie Jean Baptiste
- Asyraf Amirul
- Atangana Fouda
- Atia Ahmed
- Atif Minahel
- Atikah Ahmad Ridzuan Siti Nurul
- Atique Anika
- Atlowly Moad
- Attanyake AM Udara Lakshan
- Auchabie Johann
- Aumaitre Hugues
- Auvet Adrien
- Axelsen Eyvind W.
- Ayad Ared
- Ayadi Kamaluddin Muhammad Aisar
- Azemar Laurène
- Azizeldin Mohammed
- Azoulay Cecile
- Babatunde Hakeem
- Bach Benjamin
- Bachelet Delphine
- Badr Claudine
- Baig Nadia
- Baillie John Kenneth
- Baird J Kevin
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- Bakar Nazreen Abu
- Bakeer Hibah Bileid
- Bakri Ashraf
- Bal Andriy
- Balakrishnan Mohanaprasanth
- Bandoh Irene
- Banheiro Bruno Sarmento
- Bani-Sadr Firouzé
- Barbalho Renata
- Barbosa Nicholas Yuri
- Barclay Wendy S.
- Barnett Saef Umar
- Barnikel Michaela
- Barrasa Helena
- Barrigoto Cleide
- Bartoli Marie
- Baruch Joaquin
- Baruch Joaquín
- Basmaci Romain
- Basri Muhammad Fadhli Hassin
- Bassi Gianluigi Li
- Batool AbdAlkarim
- Battaglini Denise
- Bauer Jules
- Bautista Rincon Diego Fernando
- Beane Abigail
- Bedossa Alexandra
- Bedu-Addo Ama Kwakyewaa
- Bee Ker Hong
- Begum Husna
- Behilill Sylvie
- Beishuizen Albertus
- Bekken Gry Kloumann
- Beljantsev Aleksandr
- Bellemare David
- Beltrame Anna
- Beltrão Beatriz Amorim
- Beluze Marine
- Ben Ashur Abir
- Benech Nicolas
- Benjiman Lionel Eric
- Bennett Suzanne
- Bento Luís
- Berdal Jan-Erik
- Berdeweel Lamis
- Bergeaud Delphine
- Bergin Hazel
- Bertoli Giulia
- Bertolino Lorenzo
- Bessis Simon
- Bevilcaqua Sybille
- Bezulier Karine
- Bhatt Amar
- Bhavsar Krishna
- Bianchi Isabella
- Bianco Claudia
- Bichoka Sandra
- Bidin Farah Nadiah
- Bin Kamarudin Mohd Nazlin
- Binnawara Muhannud
- Binti Mohd Yakop Siti Rohani
- Binti Zaidan Nor Zaila
- Bisoffi Zeno
- Biston Patrick
- Bitker Laurent
- Bittaye Mustapha
- Bitton Jonathan
- Blanco-Schweizer Pablo
- Blier Catherine
- Bloos Frank
- Blot Mathieu
- Boccia Filomena
- Bodenes Laetitia
- Bogaert Debby
- Boivin Anne-Hélène
- Bolanga Ariel
- Bolaños Isabela
- Bolze Pierre-Adrien
- Bompart François
- Bonifasius Aurelius
- Bonney Joe
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- Botelho-Nevers Elisabeth
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- Bouhour Damien
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- Boureau Anne-Sophie
- Bourke John
- Bouscambert Maude
- Bousquet Aurore
- Boyer-Besseyre Marielle
- Boylan Maria
- Bozza Fernando Augusto
- Braconnier Axelle
- Braga Cynthia
- Brandenburger Timo
- Brazzi Luca
- Breen Dorothy
- Breen Patrick
- Brewster David
- Brickell Kathy
- Brien Fionnuala O.
- Broadley Tessa
- Brotherton Helen
- Browne Alex
- Brozzi Nicolas
- Brunvoll Sonja Hjellegjerde
- Brusse-Keizer Marjolein
- Bryda Petra
- Buchtele Nina
- Bugaeva Polina
- Buisson Marielle
- Buonsenso Danilo
- Burhan Erlina
- Buri Donald
- Burrell Aidan
- Bustos Ingrid G.
- Butnaru Denis
- Bævre-Jensen Roar
- Cabie André
- Cabral Susana
- Cabrita Joana
- Cabrita Joana Alves
- Caceres Eder
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- Callaghan Annmarie O.
- Calligy Kate
- Calvache Jose Andres
- Camões João
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- Campisi Josie
- Canepa Cecilia
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- Caoili Janice
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- Carmoi Thierry
- Carney Gayle
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- Carret Marie-Christine
- Carrier François Martin
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- Cascão Mariana
- Casey Siobhan
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- Castro Ivo
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- Cattaneo Paolo
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- Cavayas Alexandros
- Cárcel Sheila
- Ceccato Adrian
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- Cevik Muge
- Chair Anissa
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- Cisneros Herreros José Miguel
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- Crump Jonathan
- Cruz Claudina
- Csete Marc
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- Cummings Matthew
- Curley Gerard
- Curlier Elodie
- Curran Colleen
- Custodio Paula
- D'Alessandro Umberto
- D'Aragon Frédérick
- D'Ortenzio Eric
- da Silva Filipe Ana
- Da Silva Fernanda Dias
- Da Silveira Charlene
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- de Loughry Gillian
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- Denis Emmanuelle
- Deplanque Dominique
- Depuydt Pieter
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- Devouge Eglantine Ferrand
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- Diallo Alpha
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- Dias André
- Diaz Juan Jose
- Diaz Priscila
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- Dibba Bakary K.
- Didier Kévin
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- Dieperink Wim
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- Dimet Jérôme
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- Docherty Annemarie B.
- Doherty Helen
- Dominguez Carmen Infante
- Dondorp Arjen M.
- Donnelly Christl A.
- Donohue Sean
- Donohue Yoann
- Doran Peter
- Dorival Céline
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- Downing Mark
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- Duah Ibrahim Kwaku
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- Ducancelle Alexandre
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- Durham Lucian
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- Ean Sim Choon
- Ebo Ada
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- Edelstein Michael
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- Leeming Gary
- Lefebvre Bénédicte
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- Lopez-Colon Dalia
- Loschner Anthony L.
- Loubet Paul
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- Maillet Mylène
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- McDonald Sarah E.
- McElroy Aine
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- McEvoy Natalie
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- McLean Kenneth A.
- McNally Paul
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- Mohammed Nassima Si
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- Mohan Shetty Dr. Rajesh
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- Mohd Noordin Nurul Amani
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- Nabil Hasan Mohammad Ali
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- Ohshimo Shinichiro
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- Olliaro Piero L.
- Ondobo Pierre
- Ong David S. Y.
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- Paul Christelle
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- Paxton William A.
- Payen Jean-François
- Peake Sandra L.
- Peariasamy Kalaiarasu
- Peek Giles J.
- Peelman Florent
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- Pritchard Mark G.
- Pritchard Mark G.
- Proença Lucia
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- Rida Hajij Fatima Mhd
- Rios Ana L.
- Rishu Asgar
- Rispal Patrick
- Risso Karine
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- Roberts Charles
- Roberts Stephanie
- Robertson David L.
- Robineau Olivier
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- Sarmiento Iam Claire E.
- Sarton Benjamine
- Satya Ankana
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- Schroll Stephan
- Schwameis Michael
- Schwartz Gary
- Scott Janet T.
- Scott-Brown James
- Sedillot Nicholas
- Seitz Tamara
- Selvanayagam Jaganathan
- Selvarajoo Mageswari
- Semedi Bambang Pujo
- Semple Malcolm G.
- Senian Rasidah Bt
- Senneville Eric
- Sepulveda Claudia
- Sequeira Filipa
- Sequeira Tânia
- Shaaban Aly Orabi Yehia Samir
- Shadowitz Ellen
- Shahidan Syamin Asyraf
- Shahla Hamza
- Shalabi Laila
- Shames Haitam
- Shankar Anuraj
- Sharjeel Shaikh
- Sharma Pratima
- Shaw Catherine A.
- Shaw Victoria
- Sheenan John Robert
- Sheikh Naseem Ali
- Shetty Rohan
- Shiekh Mohiuddin
- Shime Nobuaki
- Shimizu Keiki
- Shrapnel Sally
- Shrestha Pramesh Sundar
- Shrestha Shubha Kalyan
- Shukeri Wan Fadzlina Wan Muhd
- Shum Hoi Ping
- Siang Ng Yong
- Siaw-Frimpong Moses
- Sibiude Jeanne
- Sibounheuang Bountoy
- Siddig Nidhal
- Siddiqui Atif
- Siddiqui Maqsood Ahmed
- Sigfrid Louise
- Sikander Rana Imran
- Sillah Fatoumata
- Sillaots Piret
- Silva Catarina
- Silva Maria Joao
- Silva Rogério
- Sin Wai Ching
- Sinatti Dario
- Singh Mahendra
- Singh Punam
- Sitompul Pompini Agustina
- Sivam Karisha
- Skeie Linda Gail
- Skogen Vegard
- Smith Sue
- Smood Benjamin
- Smyth Coilin
- Snacken Morgane
- So Dominic
- Soh Tze Vee
- Solberg Lene Bergendal
- Solomon Joshua
- Solomon Tom
- Somers Emily
- Sommet Agnès
- Song Myung Jin
- Song Rima
- Song Tae
- Sotto Albert
- Soum Edouard
- Sousa Ana Chora
- Sousa Marta
- Souza-Dantas Vicente
- Sow Mamadou Saliou
- Sperry Alexandra
- Spinuzza Elisabetta
- Sriskandan Shiranee
- Stabler Sarah
- Staudinger Thomas
- Stecher Stephanie-Susanne
- Steinsvik Trude
- Stienstra Ymkje
- Stiksrud Birgitte
- Stolz Eva
- Stone Amy
- Streinu-Cercel Adrian
- Streinu-Cercel Anca
- Strong Geoff
- Stuart Ami
- Stuart David
- Su Richa
- Subekti Decy
- Suen Gabriel
- Suen Jacky Y.
- Sukumar Prasanth
- Sultana Asfia
- Summers Charlotte
- Supic Dubravka
- Suppiah Deepashankari
- Surovcová Magdalena
- Suwarti Atie
- Svistunov Andrey
- Sweeney Lisa Mc
- Syahrin Sarah
- Sylverken Augustina
- Syrigos Konstantinos
- Sztajnbok Jaques
- Szuldrzynski Konstanty
- Søraas Arne
- Tabrizi Shirin
- Taccone Fabio S.
- TagElser Mohammed Ali Maha
- Tagherset Lysa
- Taib Shahdattul Mawarni
- Taleb Sara
- Talla Cheikh
- Talsma Jelmer
- Tamisier Renaud
- Tamlihat Younes Ait
- Tampubolon Maria Lawrensia
- Tan Kim Keat
- Tan Yan Chyi
- Tanaka Hiroyuki
- Tanaka Taku
- Taniguchi Hayato
- Taqdees Huda
- Taqi Arshad
- Tardivon Coralie
- Tarhabat Ali
- Tattevin Pierre
- Taufik M Azhari
- Tawfik Hassan
- Tee Tze Yuan
- Teixeira João
- Tejada Sofia
- Tellier Marie-Capucine
- Teoh Sze Kye
- Teotonio Vanessa
- Terrier Olivier
- Terzi Nicolas
- Tessier-Grenier Hubert
- Tey Adrian
- Téoulé François
- Thakur Anand
- Tham Zhang Duan
- Thangavelu Suvintheran
- Theron Elmi
- Thibault Vincent
- Thiberville Simon-Djamel
- Thill Benoît
- Thirumanickam Jananee
- Tho Leong Chin
- Thompson Niamh
- Thompson Shaun
- Thomson David
- Thomson Emma C.
- Thorpe Mathew
- Thurai Surain Raaj Thanga
- Thwaites Ryan S.
- Tierney Paul
- Tieroshyn Vadim
- Timashev Peter S.
- Timsit Jean-François
- Tirupakuzhi Vijayaraghavan Bharath Kumar
- Tirupakuzhi Vijayaraghavan Bharath Kumar
- Tissot Noémie
- Toal Fiona
- Toki Maria
- Tonby Kristian
- Tonnii Sia Loong
- Torre Marta
- Torres Antoni
- Torres Margarida
- Torres-Zevallos Hernando
- Tounkara Aboubacar
- Towers Michael
- Traoré Fodé Amara
- Trapani Tony
- Tromeur Cécile
- Trontzas Ioannis
- Trouillon Tiffany
- Truong Jeanne
- Tual Christelle
- Tubiana Sarah
- Tuite Helen
- Turgeon Alexis F.
- Turmel Jean-Marie
- Turtle Lance C. W.
- Tveita Anders
- Twardowski Pawel
- Uchiyama Makoto
- Udayanga PG Ishara
- Udy Andrew
- Ullah Arslan Rahat
- Ullrich Roman
- Uribe Alberto
- Usman Asad
- Usuf Effua
- Uva Maria Sousa
- Uyeki Timothy M.
- Vaillant Michel
- Vajdovics Cristinava
- Val-Flores Luís
- Valentini Piero
- Van de Velde Stijn
- van den Berge Marcel
- van der Feltz Machteld
- van der Palen Job
- van der Valk Paul
- Van Der Vekens Nicky
- Van der Voort Peter
- Van Der Werf Sylvie
- van Gulik Laura
- Van Hattem Jarne
- van Netten Carolien
- van Veen Ilonka
- Vanel Noémie
- Vanoverschelde Henk
- Varrone Michael
- Vasconcelos Malte Kohns
- Vasudayan Shoban Raj
- Vauchy Charline
- Vecham Pavan Kumar
- Veeran Shaminee
- Veislinger Aurélie
- Vencken Sebastian
- Ventura Sara
- Verbon Annelies
- Vidal José Ernesto
- Vieira César
- Vijayan Deepak
- Villar Judit
- Villeneuve Pierre-Marc
- Villoldo Andrea
- Vishwanathan Gayatri
- Visseaux Benoit
- Visser Hannah
- Vitiello Chiara
- Vongsouvath Manivanh
- Vonkeman Harald
- Vuotto Fanny
- Wahab Noor Hidayu
- Wahab Suhaila Abdul
- Wahid Nadirah Abdul
- Wainstein Marina
- Walsh Laura
- Wang Chih-Hsien
- Webb Steve
- Wei Jia
- Wei Jia
- Weil Katharina
- Wen Tan Pei
- Wesam Hassi
- Wesselius Sanne
- West T. Eoin
- Wham Murray
- Whelan Bryan
- White Nicole
- Wicky Paul Henri
- Wiedemann Aurélie
- Wijaya Surya Otto
- Wille Keith
- Willems Sue
- Williams Bailey
- Williams Patricia J.
- Williams Virginie
- Wils Evert-Jan
- Wils Evert-Jan
- Wittman Jessica
- Wong Calvin
- Wong Teck Fung
- Wong Xin Ci
- Wong Yew Sing
- Wright Natalie
- Xian Lim Saio
- Xynogalas Ioannis
- Yamazaki Masaki
- Yang Toh Jordan Zhien
- Yarad Elizabeth
- Yazdanpanah Yazdan
- Yelnik Cécile
- Yeoh Chian Hui
- Yerkovich Stephanie
- Yiaye Touxiong
- Yokoyama Toshiki
- Yonis Hodane
- Yousif Obada
- Yuliarto Saptadi
- Zaaqoq Akram
- Zabbe Marion
- Zabert Gustavo E.
- Zacharowski Kai
- Zahid Masliza
- Zahran Maram
- Zambon Maria
- Zambrano Miguel
- Zanella Alberto
- Zaynah Nurul
- Zayyad Hiba
- Zoufaly Alexander
- Zucman David
- Publication venue
- Publication date
- 30/05/2024
- Field of study
Background: COVID-19 is primarily known as a respiratory illness; however, many patients present to hospital without respiratory symptoms. The association between non-respiratory presentations of COVID-19 and outcomes remains unclear. We investigated risk factors and clinical outcomes in patients with no respiratory symptoms (NRS) and respiratory symptoms (RS) at hospital admission. Methods: This study describes clinical features, physiological parameters, and outcomes of hospitalised COVID-19 patients, stratified by the presence or absence of respiratory symptoms at hospital admission. RS patients had one or more of: cough, shortness of breath, sore throat, runny nose or wheezing; while NRS patients did not. Results: Of 178,640 patients in the study, 86.4 % presented with RS, while 13.6 % had NRS. NRS patients were older (median age: NRS: 74 vs RS: 65) and less likely to be admitted to the ICU (NRS: 36.7 % vs RS: 37.5 %). NRS patients had a higher crude in-hospital case-fatality ratio (NRS 41.1 % vs. RS 32.0 %), but a lower risk of death after adjusting for confounders (HR 0.88 [0.83-0.93]). Conclusion: Approximately one in seven COVID-19 patients presented at hospital admission without respiratory symptoms. These patients were older, had lower ICU admission rates, and had a lower risk of in-hospital mortality after adjusting for confounders