World society of emergency surgery (WSES) guidelines for management of skin and soft tissue infections

Skin and soft tissue infections (SSTIs) encompass a variety of pathological conditions ranging from simple superficial infections to severe necrotizing soft tissue infections. Necrotizing soft tissue infections (NSTIs) are potentially life-threatening infections of any layer of the soft tissue compartment associated with widespread necrosis and systemic toxicity. Successful management of NSTIs involves prompt recognition, timely surgical debridement or drainage, resuscitation and appropriate antibiotic therapy. A worldwide international panel of experts developed evidence-based guidelines for management of soft tissue infections. The multifaceted nature of these infections has led to a collaboration among surgeons, intensive care and infectious diseases specialists, who have shared these guidelines, implementing clinical practice recommendations

World Society of Emergency Surgery (WSES) guidelines for management of skin and soft tissue infections

Peer reviewe

V&V assessment package instantiation in ICT-based manufacturing - Experiences from ten industrial use cases

This paper describes the instantiation process of a Verification & Validation (V&V) method developed for evaluating the implementation of Future Internet components in a multi-sectorial environment. ICT systems represent a key competitive factor for enterprises, and new application development paradigms are emerging with e.g. a modular approach based on standard, open and cloud-based components. The utilization of modules coming from different sources emphasizes the need for a sound V&V approach in order to ensure that the final solution is of quality, accords to the existing standard and at the same time addresses the original business needs. The proposed approach is based on a standard V&V methodology characterized by a structured assessment of the software quality at different levels and a reduced set of business indicators able to evaluate the business impact of the integrated solution; all of these are deployed via a configurable V&V Package based on a web interface. At the end of the paper the practical experiences and lessons learned from our work are also described

Outcome following surgical stabilization of distal diaphyseal and supracondylar femoral fractures in dogs

Signalment, clinical features, fixation techniques, complications, and outcome for dogs presenting with distal diaphyseal and supracondylar femoral fractures were retrospectively reviewed. A total of 45 dogs with unilateral femoral fractures were included. Supracondylar femoral plates were the most popular method of fixation. However, various fixation techniques resulted in favorable outcomes in most dogs with 19/45 cases achieving full function and 22/45 achieving acceptable function. Degree of fracture comminution did not appear to affect complication rate or be a surrogate for worse clinical outcome