Recrutamento de docentes de Matemática no ensino superior: um caso no ISCAL

Carta abert

Tumors of the Foot and Ankle: A Single-institution Experience

Tumors of the foot and ankle are rare, and the particular clinicopathologic features, therapeutic approach, and outcomes in this setting are not well established. From January 2000 to December 2010, 72 patients with primary musculoskeletal tumors of the foot and ankle, both benign and malignant, were treated at a single institution. Of the 72 patients, 56% were female. The median age was 52 years. Of the 72 tumors, 62 (86.11%) were located in the foot and 10 were located in the ankle; 63 (87.5%) were soft tissue tumors and 9 (12.5%) were bone tumors. Overall, 56 (78%) were benign tumors and 16 (22%) were malignant tumors. The most frequent soft tissue and bone diagnosis was giant cell tumor. The median follow-up period was 49 months. The vast majority of the tumors were located in the foot. Benign tumors were dominant, outnumbering malignant tumors by more than 3 to 1. The diversity of the histologic benign types was evident, with giant cell tumor, angiomyoma, and lipoma the most frequent. Regarding the malignant tumors, a clear male predominance was present, the median age was 45 years, and the most frequent tumor was synoviosarcoma. The 9-year overall and disease-free survival rate was 65% and 40%, respectively

TEMPERATURAS MÍNIMAS E TIPOS DE TEMPO DO INVERNO EM RIO CLARO – SP

Resumo Este trabalho estuda a ocorrência de temperaturas inferiores a 15º C, no período de inverno, de 1995 a 2012, na cidade de Rio Claro – SP, Brasil, localizada a 22º 25’ S e 47º 34’ W, relacionando-as à circulação atmosférica e à qualidade do ar. Analisa episódios favoráveis à má qualidade do ar e ao registro de frio mais intenso, e conclui que há uma grande variabilidade das temperaturas mínimas nesta estação do ano, associada, principalmente, às temperaturas do Oceano Pacífico Equatorial. Conclui, também, que os dias e horas com temperaturas inferiores a 15º C estão diminuindo acentuadamente, para, provavelmente, deixarem de ocorrer, após 2035, na área urbana de Rio Claro. Palavras-chave: Temperatura. Variabilidade Climática. Mudança Climática. Qualidade do Ar. Abstract This paper studies the occurrence of temperatures below 15º C in winter period, from 1995 to 2012 in the city of Rio Claro – State of São Paulo, Brazil, located at 22º 25' S and 47º 34' W, relating them to the atmospheric circulation and air quality. Besides analyzing favorable episodes of poor air quality and the occurrence of more intense cold, the conclusion is that there is a great variability in minimum temperatures this season, mainly associated to the Equatorial Pacific Ocean temperatures, and that the days and hours with temperatures below 15º C are declining sharply, for probably fail to occur after 2035 in the urban area of Rio Claro. Keywords: Temperature. Climate Variability, Climate Change. Air Quality. Resumen Este trabajo estudia la aparición de temperaturas inferiores a 15º C en el periodo de invierno, de 1995 a 2012, en la ciudad de Río Claro – SP, Brasil, situada a 22º 25' S y 47º 34' W, habiendo una relación entre la circulación atmosférica y la calidad del aire. Además de analizar los episodios favorables a la mala calidad del aire y al registro del frío más intenso, la investigación concluye que existe una gran variabilidad de temperaturas mínimas en esta temporada (invierno) principalmente asociada a las temperaturas del Océano Pacífico Ecuatorial, y que los días y horas con temperaturas inferiores a 15º C están disminuyendo drásticamente, para que probablemente dejen de ocurrir después de 2035 en el área urbana de Río Claro. Palabras clave: Temperatura. Variabilidad del Clima, Cambio Climático, Calidad del Aire

AQUECIMENTO GLOBAL E MUDANÇAS CLIMÁTICAS NA VISÃO DE ESTUDANTES DO ENSINO MÉDIO

RESUMO Este trabalho, por meio de entrevistas realizadas em meados de 2009, nas cidades de São Bernardo do Campo, Santo Antonio de Posse, Pederneiras e Tapiratiba, localizadas no Estado de São Paulo. Buscou saber se os alunos do ensino médio tinham informações a respeito do aquecimento global e, diante de respostas afirmativas, procurou conhecer as principais fontes de informação a que eles tiveram acesso e suas posições pessoais diante de um assunto polêmico. Verificou-se que, sobre mudanças climáticas, suas causas e consequências, os discentes adquirem mais informação na televisão e na internet do que na escola, o que é preocupante, haja vista que os fatos divulgados pelas redes televisivas e pela rede mundial de computadores são, muitas vezes, alarmistas e desprovidos de fundamentos científicos. Palavras-chave: Aquecimento Global. Mudanças Climáticas. Política Estadual de Mudanças Climáticas. Mídia. Medidas Mitigadoras. Ensino Médio. ABSTRACT This study, wasconducted through interviews in mid-2009 in the cities of São Bernardo do Campo, Santo Antonio de Posse, Pederneiras and Tapiratiba, located in São Paulo State. The aim was to evaluate if high school students had information about the global warming and, in front of affirmative answers, and also, to know what was the main sources of information they had access and their personal views on a controversial subject. Regarding the climate changes and its causes and consequences, it was found that students acquire more information through television and internet than in school, which is worrying, given that the facts disclosed by the television networks and the worldwide computers network, are often alarmist and lacking scientific foundation. Keywords: Global Warming. Climate Changes. State Policy on Climate Changes. Media. Mitigation measures. High School. RESUMEN Este estudio, a través de entrevistas realizadas a mediados de 2009, en las ciudades de São Bernardo do Campo, Santo Antonio de Posse, y Pederneiras, ubicadas en Estado de São Paulo. Buscó saber si los alumnos de escuela secundaria tenían alguna información con respecto al calentamiento global, y con respuestas afirmativas, trató de conocer las principales fuentes de información que tuvieron acceso y a sus propias posiciones delante de un asunto tan polémico. Se encontró que, sobre cambios climáticos sus causas y consecuencias, los estudiantes adquieren más información en la televisión y por Internet que en la escuela, lo cual es preocupante, dado que los hechos divulgados por la red televisiva y por la red mundial de computadoras que a menudo son alarmistas y desprevenidos de fundamentos científicos. Palabras claves: El calentamiento Global. El Cambio Climático. Política del Estado en el Cambio Climático. Medios de Comunicación. Medidas Mitigadoras. Escuela Secundari

Absent abdominal muscles, nephro-urologic abnormalities, and severe neurologic damage in an infant with 3 chromosomal duplications: A novel syndrome?

Absent abdominal muscles, cryptorchidism, and hydroureteronephrosis are known to occur in the prune belly syndrome (PBS). We present a male with absent abdominal muscles, severe neurologic damage, with global developmental delay, hydroureteronephrosis, and cryptorchidism. The patient also had arthrogryposis multiplex congenital, low set ears, short neck, micrognathia, bilateral total ptosis, and bilateral clubfeet. Genetic testing (CGH array) revealed 3 novel duplications of unknown clinical significance at 7q11.23, 9q22.32 (PTCH 1 gene), and 12q21.32 (CEP 290 gene).Conclusion: We feel that our patient represents a novel entity, henceforth not described in the literature

Wavelet entropy of stochastic processes

We compare two different definitions for the wavelet entropy associated to stochastic processes. The first one, the Normalized Total Wavelet Entropy (NTWS) family [Phys. Rev. E 57 (1998) 932; J. Neuroscience Method 105 (2001) 65; Physica A (2005) in press] and a second introduced by Tavares and Lucena [Physica A 357 (2005)~71]. In order to understand their advantages and disadvantages, exact results obtained for fractional Gaussian noise (-1<alpha< 1) and the fractional Brownian motion (1 < alpha < 3) are assessed. We find out that NTWS family performs better as a characterization method for these stochastic processes.Comment: 12 pages, 4 figures, submitted to Physica

Adding Evidence to the Role of NEUROG1 in Congenital Cranial Dysinnervation Disorders

Congenital cranial dysinnervation disorders (CCDDs) are a heterogeneous group of neurodevelopmental phenotypes caused by a primary disturbance of innervation due to deficient, absent, or misguided cranial nerves. Although some CCDDs genes are known, several clinical phenotypes and their aetiologies remain to be elucidated. We describe a 12-year-old boy with hypotonia, developmental delay, sensorineural hearing loss, and keratoconjunctivitis due to lack of corneal reflex. He had a long expressionless face, severe oromotor dysfunction, bilateral agenesis/severe hypoplasia of the VIII nerve with marked atresia of the internal auditory canals and cochlear labyrinth malformation. Trio-exome sequencing identified a homozygous loss of function variant in the NEUROG1 gene (NM_006161.2: c.202G > T, p.Glu68*). NEUROG1 is considered a causal candidate for CCDDs based on (i) the previous report of a patient with a homozygous gene deletion and developmental delay, deafness due to absent bilateral VIII nerves, and severe oromotor dysfunction; (ii) a second patient with a homozygous NEUROG1 missense variant and corneal opacity, absent corneal reflex and intellectual disability; and (iii) the knockout mouse model phenotype which highly resembles the disorder observed in humans. Our findings support the growing compelling evidence that loss of NEUROG1 leads to a very distinctive disorder of cranial nerves development.info:eu-repo/semantics/publishedVersio

Diethylenetriamine/diamines/copper (II) complexes [Cu(dien)(NN)]Br2: Synthesis, solvatochromism, thermal, electrochemistry, single crystal, Hirshfeld surface analysis and antibacterial activity

Two dicationic water soluble mixed triamine/diamine copper (II) complexes, of general formula [Cu(dien)NN]Br2(1–2) [dien = diethelenetriamine and NN is en = ethylenediamine or Me4en = N,N′,N,N′-tetramethylethylenediamine] were prepared under ultrasonic mode with a relatively high yield. These complexes were characterized by elemental microanalysis, UV visible IR spectroscopy, and thermal and electrochemical techniques. In addition, complex 2 structure was solved by X-ray single crystal and Hirshfeld surface analysis. The complex exhibits a distorted square pyramidal coordination environment around Cu(II) centre. The solvatochromism of the desired complexes was investigated in water and other suitable organic solvents. The results show that the Guttmann’s DN parameter values of the solvents have mainly contributed to the shift of the d–d absorption band towards the linear increase in the wavelength of the absorption maxima of the complexes. The complex 1 showed higher antibacterial activity against the studied microorganisms compared to complex 2. Both complexes revealed promising antibacterial activities.The authors would like to extend their sincere appreciation to the Deanship of Scientific Research at King Saud University for its funding of this Research group NO (RG-0257-1435-1436)

Retinal Neurodegeneration in Diabetic Patients Without Diabetic Retinopathy

PURPOSE: To compare the thickness of all retinal layers between a nondiabetic group and diabetic patients without diabetic retinopathy (DR). METHODS: Cross-sectional study, in which all subjects underwent an ophthalmic examination including optical coherence tomography. After automatic retinal segmentation, each retinal layer thickness (eight separate layers and overall thickness) was calculated in all nine Early Treatment Diabetic Retinopathy Study (ETDRS) areas. The choroidal thickness (CT) also was measured at five locations. Generalized additive regression models were used to analyze the data. RESULTS: A total of 175 patients were recruited, 50 nondiabetic subjects and 125 diabetic patients without DR, stratified into three groups according to diabetes duration: group I (10 years, n = 31). Overall, groups I and III of diabetic patients had a decrease in the photoreceptor layer (PR) thickness, when compared with the nondiabetic subjects in six ETDRS areas (P < 0.0007). Patients with more recent diagnosis (group I) had thinner PR than those with moderate duration (group II). Interestingly, patients with longer known disease (group III) had the thinnest PR values. There were no overall differences in the remaining retinal parameters. CONCLUSIONS: Retinal thickness profile is not linear throughout disease duration. Even in the absence of funduscopic disease, PR layer in diabetic patients seems to differ from nondiabetic subjects, thus suggesting that some form of neurodegeneration may take place before clinical signs of vascular problems arise.info:eu-repo/semantics/publishedVersio

Produtos de contraste iodados

A aplicação na medicina dos produtos de contraste iodados é uma realidade com a qual a generalidade dos médicos deve estar familiarizada. Através de uma abordagem sucinta, o presente artigo pretende simplificar a compreensão dos diversos tipos de contraste, suas propriedades, utilidade clínica e reacções adversas