浸潤性発育を示した後腹膜孤立線維性腫瘍の1例

56歳女.悪性後腹膜孤立性線維性腫瘍であり, 主訴は腹部腫瘤触知で, 腹部CT及びMRI検査にて左腎下方に接して, Gerota筋膜に沿うように発育する境界不明瞭な腫瘤を認めた.手術所見では後腹膜腔にゼラチン状の腫瘍を認め, 下行結腸周囲の脂肪組織やGerota筋膜周囲の脂肪組織に浸潤していた.Gerota筋膜内への浸潤は認めなかったので左腎は温存した.病理組織像では間質の膠原線維は著明に増殖し, hemangiopericytoma様のくちばし状を呈する血管も豊富に認められた.腫瘍組織内に腫瘍細胞密度の増加しているところや核異型度が強く分裂像を認める組織が混在しており, また周囲脂肪組織内に浸潤している所見を認めた.以上より, 悪性後腹膜孤立性線維性腫瘍と診断した.治療は外科的切除のみを行い, 2年4ヵ月を経過しても再発無く生存中であるSolitary fibrous retroperitoneal tumor is rare. We present a case with infiltrative growth in a 56-year-old female patient whose initial symptom was palpable tumor in the lower abdomen. Computed tomography and magnetic resonance imaging indicated a mass in the retroperitoneum under the left kidney with a poorly demarcated infiltrative growth. Surgical findings revealed a gelatinous tumor in the retroperitoneum, which had invaded up to the fatty tissue surrounding the Gerota's fascia and to the fatty tissue surrounding the descending colon. However, as there was no invasion into the Gerota's fascia, it was possible to preserve the left kidney. Pathohistological examination revealed increased cellularity in the tumor tissues as well as tissues with atypical nuclei of the tumor cells with some cell division. Due to these findings, it was diagnosed as malignant solitary fibrous tumor. Only surgical treatment was performed and the patient is alive without recurrence 2 years and 4 months after surgery

Competition between oxygen reordering and internal strain for the pressure effect of the Hall coefficient in Y1-xCaxBa2Cu3Oy

The pressure effect on the Hall coefficient RH has been studied in Ca and oxygen co-doped Y12xCaxBa2Cu3Oy systems. RH is not altered by pressure in samples without a Cu-O chain, whereas samples with an oxygen-deficient chain are altered in response to pressure, thus demonstrating the contribution of the oxygen reordering effect. However, even in samples with full chain ordering, RH changes at a rate of 28.3%/GPa. This suggests the contribution of internal strain due to the presence of a Cu-O chain structure. We independently estimated the effect of two factors, oxygen reordering and internal strain, on the pressure effect on RH . The oxygen-content dependence of the pressure effect on RH can be explained by competition between oxygen reordering and internal strain

Pseudogap and superconductivity on a common scale of hole concentration for high-Tc superconductors

authorRoom-temperature thermoelectric power S^290 as a function of hole concentration per planer Cu atom (P_pl) has been studied in a chain-free double-layer Y_1−_xCa_xBa_2Cu_3O_6. S^290(P_pl) of Y_1−_xCa_xBa_2Cu_3O_6 (P_pl=x/2) behaves identically to that of single-layer La_2−_xSr_xCuO_4 (P_pl=x). In order to show the validity of the present scale of S^290(P_pl), we demonstrate the phase diagram for bilayer Yba_2Cu_3O_y system and Bi_2Sr_2CaCu_2O_y system and discuss

In situ preparation of highly fluorescent pyrene-dyes from non-luminous precursors upon photoirradiation

The non-luminous precursor, 2-(1-pyrenyl)-9,10-dihydro-9,10-ethanoanthracene-11,12-dione, was photochemically converted to highly-fluorescent 2-(1-pyrenyl)anthracene quantitatively in solution and in the PMMA film and the fluorescence quantum yield of the acene in benzonitrile was as high as 0.99

Assesment of F-FDG PET/CT texture analysis to discriminate NSCLC from radiation pneumonitis after CIRT

Aim: The differentiation of local recurrence from a primary tumor and radiation pneumonitis (RP) is critically important for selecting optimal clinical therapeutic strategies to manage post carbon-ion radiotherapy (CIRT) in patients with non-small cell lung cancer (NSCLC). Although 18F-FDG PET/CT (FDG-PET/CT) plays a key role in the metabolic imaging of patients with NSCLC who require CIRT management, PET/CT diagnosis based on SUVmax cannot always distinguish between NSCLC and RP. The present study aimed to determine whether FDG-PET/CT texture parameters can differentiate NSCLC from RP after CIRT.Material and Methods: We retrospectively analyzed FDG-PET/CT image data from 32 patients with histopathologically proven NSCLC who were scheduled to undergo CIRT, and 31 patients who were diagnosed with RP after CIRT (50.0 Gy in 4 fractions/day). Radiation pneumonitis was diagnosed by biopsy or at clinical follow-up > 1 year after CIRT. Volumes of interest (VOI) on tumors were delineated using a threshold of 40% of the maximum standard uptake value (SUVmax) in each lesion. The SUV parameters of SUVmax, SUVpeak, SUVmean, metabolic tumor volume (MTV), total lesion glycolysis (TLG) and seven typical texture parameters of FDG-PET/CT were determined using PETSTAT image-analysis software. Data were statistically compared between NSCLC and RP using nonparametric Wilcoxon rank sum tests. Diagnostic accuracy was assessed using ROC curves.Results: Among SUV parameters, MTV (p < 0.0001) and TLG (p = 0.001) significantly differed between NSCLC and RP. The feature quantities of texture parameters, namely, GLRLM, GLSZM, NGLCM3D, NGLCM and NGTDM significantly differed between NSCLC and RP. The areas under the receiver operating characteristics (ROC) curves (AUC) were as follows: SUVmax 0.64, MTV 0.86, TLG 0.75, GLRLM 0.83, GLSZM 0.76, NGLCM3D 0.71, NGLCM 0.72 and GTDM 0.82. Diagnostic accuracy was better using GLRLRM or NGTDM than SUVmax (p < 0.01). Conclusion: The texture parameters of FDG-PET/CT were useful to differentiate NSCLC from radiation pneumonitis after CIRT, and GLRLM and NGTDM in particular would be promising parameters with excellent diagnostic accuracy.EANM2019(ヨーロッパ核医学会