Neotropical Freshwater Fishes: A dataset of occurrence and abundance of freshwater fishes in the Neotropics

The Neotropical region hosts 4225 freshwater fish species, ranking first among the world's most diverse regions for freshwater fishes. Our NEOTROPICAL FRESHWATER FISHES data set is the first to produce a large-scale Neotropical freshwater fish inventory, covering the entire Neotropical region from Mexico and the Caribbean in the north to the southern limits in Argentina, Paraguay, Chile, and Uruguay. We compiled 185,787 distribution records, with unique georeferenced coordinates, for the 4225 species, represented by occurrence and abundance data. The number of species for the most numerous orders are as follows: Characiformes (1289), Siluriformes (1384), Cichliformes (354), Cyprinodontiformes (245), and Gymnotiformes (135). The most recorded species was the characid Astyanax fasciatus (4696 records). We registered 116,802 distribution records for native species, compared to 1802 distribution records for nonnative species. The main aim of the NEOTROPICAL FRESHWATER FISHES data set was to make these occurrence and abundance data accessible for international researchers to develop ecological and macroecological studies, from local to regional scales, with focal fish species, families, or orders. We anticipate that the NEOTROPICAL FRESHWATER FISHES data set will be valuable for studies on a wide range of ecological processes, such as trophic cascades, fishery pressure, the effects of habitat loss and fragmentation, and the impacts of species invasion and climate change. There are no copyright restrictions on the data, and please cite this data paper when using the data in publications.Fil: Tonella, Lívia Helena. Universidade Estadual de Maringá. Departamento de Engenharia Química. Laboratorio de Pesquisa.; BrasilFil: Ruaro, Renata. Universidade Estadual de Maringá. Departamento de Engenharia Química. Laboratorio de Pesquisa.; BrasilFil: Daga, Vanessa Salete. Universidade Federal do Paraná; BrasilFil: Garcia, Diego Azevedo Zoccal. Universidade Estadual de Londrina; BrasilFil: Barroso Vitorino Júnior, Oscar. Instituto Natureza do Tocantins-Naturatins; BrasilFil: Lobato de Magalhães, Tatiana. Universidad Autonoma de Queretaro.; MéxicoFil: Reis, Roberto Esser. Museu de Ciências e Tecnologia; BrasilFil: Di Dario, Fabio. Universidade Federal do Rio de Janeiro; BrasilFil: Petry, Ana Cristina. Universidade Federal do Rio de Janeiro; BrasilFil: Mincarone, Michael Maia. Universidade Federal do Rio de Janeiro; BrasilFil: Assis Montag, Luciano Fogaça. Universidade Federal do Pará; BrasilFil: Pompeu, Paulo Santos. Universidade Federal de Lavras; BrasilFil: Teixeira, Adonias Aphoena Martins. Universidade Estadual da Paraiba; BrasilFil: Carmassi, Alberto Luciano. Universidade Federal de Sao Paulo; Brasil. Universidade Federal do São Carlos; BrasilFil: Sánchez, Alberto J.. Universidad Juárez Autónoma de Tabasco; MéxicoFil: Giraldo Pérez, Alejandro. Universidade Federal de Minas Gerais; BrasilFil: Bono, Alessandra. Universidad de Vale do Rio dos Sinos; BrasilFil: Datovo, Aléssio. Universidade de Sao Paulo; BrasilFil: Flecker, Alexander S.. Cornell University; Estados UnidosFil: Sanches, Alexandra. Universidade de Sao Paulo; Brasil. Universidade Federal do São Carlos; BrasilFil: Godinho, Alexandre Lima. Universidade Federal de Minas Gerais; BrasilFil: Matthiensen, Alexandre. Embrapa Suínos e Aves; BrasilFil: Peressin, Alexandre. Universidade Federal de Lavras; BrasilFil: Silva Hilsdorf, Alexandre Wagner. Universidade de Mogi das Cruzes; BrasilFil: Barufatti, Alexéia. Universidade Federal da Grande Dourados; BrasilFil: Hirschmann, Alice. Universidade Federal do Pampa; BrasilFil: Jung, Aline. Universidade Do Estado de Mato Grosso (unemat);Fil: Cruz Ramírez, Allan K.. Universidad Juárez Autónoma de Tabasco; MéxicoFil: Braga Silva, Alline. Instituto Federal de Goiás; BrasilFil: Cunico, Almir Manoel. Universidade Federal do Paraná; BrasilFil: Tagliaferro, Marina Beatriz. Consejo Nacional de Investigaciones Científicas y Técnicas. Centro Austral de Investigaciones Científicas; Argentina. Consejo Nacional de Investigaciones Científicas y Técnicas. Centro Científico Tecnológico Conicet - Córdoba. Instituto de Diversidad y Ecología Animal. Universidad Nacional de Córdoba. Facultad de Ciencias Exactas Físicas y Naturales. Instituto de Diversidad y Ecología Animal; Argentin

Predictors of atrial fibrillation in ibrutinib-treated CLL patients: a prospective study

Abstract Background Ibrutinib is an oral irreversible inhibitor of Bruton’s tyrosine kinase, indicated for the treatment of chronic lymphocytic leukaemia. The drug is generally well tolerated; however, not infrequent side effects are reported, with the major two being bleeding and ibrutinib-related atrial fibrillation. Atrial fibrillation pathogenesis in this setting is not completely clear, and no prospective studies have evaluated the impact of previous cardiologic history and baseline characteristics. Methods We prospectively performed cardiologic assessment in 43 CLL patients before starting ibrutinib therapy. Cardiologic workup included comorbidity collection and electrocardiographic and echocardiographic baseline evaluation. Results After a median observation of 8 months, seven patients developed atrial fibrillation (16.3%). Cases developing atrial fibrillation were all elderly males (p = 0.04), and mostly with a history of previous arterial hypertension (p = 0.009). Atrial fibrillation occurrence also correlated with the presence of one or more pre-existent cardiologic comorbidities (p = 0.03), with a higher atrial fibrillation risk score (calculated with comorbidities and cardiologic risk factor evaluation p < 0.001), and with higher left atrial diameter (p = 0.02) and area (p = 0.03) by echocardiography. The occurrence of atrial fibrillation was managed after an integrated cardio-oncologic evaluation: anticoagulation was started in 4 (57.1%) patients and beta-blockers or amiodarone in 5 (71.4%). One patient underwent electric cardioversion and another patient pacemaker positioning to normalise heart rate in order to continue ibrutinib. Conclusion Our data show that echocardiography is a highly informative and reproducible tool that should be included in pre-treatment workup for patients who are candidates for ibrutinib therapy

Additional file 1: of Predictors of atrial fibrillation in ibrutinib-treated CLL patients: a prospective study

Supplementary material and results. (DOC 60 kb

Association between EAT and US degree of steatosis.

<p>EAT according to US fatty liver grade, (p<0.001 for trend).</p

Characteristics of 512 patients with the overall series of NAFLD according to gender.

<p>Characteristics of 512 patients with the overall series of NAFLD according to gender.</p

Characteristics of 512 patients with NAFLD divided according to EAT tertile.

<p>Characteristics of 512 patients with NAFLD divided according to EAT tertile.</p

Association between epicardial adipose tissue (EAT, mm) metabolic and clinical variables and ultrasonographic steatosis grades.

<p>Results of multiple linear regression analyses, age- and gender-adjusted and fully adjusted^{<a href="http://www.plosone.org/article/info:doi/10.1371/journal.pone.0162473#t003fn001" target="_blank">*</a>}.</p

Association of parameters of liver damage (steatosis grade 3, NASH and fibrosis>2) and EAT and metabolic and clinical variables.

<p>Results of logistic regression analyses age- and gender-adjusted and fully adjusted models (analysis performed in 100 patients with liver histology).</p

Association of parameters of cardiovascular damage (cIMT (mm), cplaques and E/A) with EAT and metabolic, clinical variables and ultrasonographic steatosis grades.

<p>Results of multiple linear (cIMT, E/A) and logistic regression (cplaques) analyses, age- and gender-adjusted and fully adjusted models^{<a href="http://www.plosone.org/article/info:doi/10.1371/journal.pone.0162473#t004fn001" target="_blank">*</a>}.</p