Nebuliser therapy in the intensive care unit

The relationship between identity, lived experience, sexual practices and the language through which these are conveyed has been widely debated in sexuality literature. For example, ‘coming out’ has famously been conceptualised as a ‘speech act’ (Sedgwick 1990) and as a collective narrative (Plummer 1995), while a growing concern for individuals’ diverse identifications in relations to their sexual and gender practices has produced interesting research focusing on linguistic practices among LGBT-identified individuals (Leap 1995; Kulick 2000; Cameron and Kulick 2006; Farqhar 2000). While an explicit focus on language remains marginal to literature on sexualities (Kulick 2000), issue of language use and translation are seldom explicitly addressed in the growing literature on intersectionality. Yet intersectional perspectives ‘reject the separability of analytical and identity categories’ (McCall 2005:1771), and therefore have an implicit stake in the ‘vernacular’ language of the researched, in the ‘scientific’ language of the researcher and in the relationship of continuity between the two. Drawing on literature within gay and lesbian/queer studies and cross-cultural studies, this chapter revisits debates on sexuality, language and intersectionality. I argue for the importance of giving careful consideration to the language we choose to use as researchers to collectively define the people whose experiences we try to capture. I also propose that language itself can be investigated as a productive way to foreground how individual and collective identifications are discursively constructed, and to unpack the diversity of lived experience. I address intersectional complexity as a methodological issue, where methodology is understood not only as the methods and practicalities of doing research, but more broadly as ‘a coherent set of ideas about the philosophy, methods and data that underlie the research process and the production of knowledge’ (McCall 2005:1774). My points are illustrated with examples drawn from my ethnographic study on ‘lesbian’ identity in urban Russia, interspersed with insights from existing literature. In particular, I aim to show that an explicit focus on language can be a productive way to explore the intersections between the global, the national and the local in cross-cultural research on sexuality, while also addressing issues of positionality and accountability to the communities researched

A novel class of microRNA-recognition elements that function only within open reading frames.

MicroRNAs (miRNAs) are well known to target 3' untranslated regions (3' UTRs) in mRNAs, thereby silencing gene expression at the post-transcriptional level. Multiple reports have also indicated the ability of miRNAs to target protein-coding sequences (CDS); however, miRNAs have been generally believed to function through similar mechanisms regardless of the locations of their sites of action. Here, we report a class of miRNA-recognition elements (MREs) that function exclusively in CDS regions. Through functional and mechanistic characterization of these 'unusual' MREs, we demonstrate that CDS-targeted miRNAs require extensive base-pairing at the 3' side rather than the 5' seed; cause gene silencing in an Argonaute-dependent but GW182-independent manner; and repress translation by inducing transient ribosome stalling instead of mRNA destabilization. These findings reveal distinct mechanisms and functional consequences of miRNAs that target CDS versus the 3' UTR and suggest that CDS-targeted miRNAs may use a translational quality-control-related mechanism to regulate translation in mammalian cells

Measurement of e + e − → ωη ′ cross sections at s = 2. 000 to 3. 080 GeV

We measured the Born cross sections for the process e+e− → ωη′ at 22 center-of-mass energies from 2.000 to 3.080 GeV with the BESIII detector at the BEPCII collider. We observed a resonant structure with a statistical significance of 9.6σ. A Breit-Wigner fit determines its mass to be MR = (2153 ± 30 ± 31) MeV/c2 and its width to be ΓR = (167 ± 77 ± 7) MeV, where the first uncertainties are statistical and the second are systematic

Search for the semi-muonic charmonium decay J/ψ → D − μ + ν μ + c. c

Using (10087 ± 44) × 106J/ψ events collected with the BESIII detector at the BEPCII e+e− storage ring at the center-of-mass energy of s = 3.097 GeV, we present a search for the rare semi-muonic charmonium decay J/ψ → D−μ+νμ + c.c.. Since no significant signal is observed, we set an upper limit of the branching fraction to be B (J/ψ → D−μ+νμ + c.c.) < 5.6 × 10−7 at 90% confidence level. This is the first search for the weak decay of charmonium with a muon in the final state

Observation of the semileptonic decays D 0 → K S 0 π − π 0 e + ν e and D + → K S 0 π + π − e + ν e

By analyzing e+e− annihilation data corresponding to an integrated luminosity of 2.93 fb−1 collected at a center-of-mass energy of 3.773 GeV with the BESIII detector, the first observation of the semileptonic decays D0→KS0π−π0e+νe and D+→KS0π+π−e+νe is reported. In the hypothesis that all events correspond to K1(1270) decays, the branching fractions are measured to be BD0→K11270−→KS0π−π0e+νe=1.69−0.46+0.53±0.15×10−4 and BD+→K¯112700→KS0π+π−e+νe=1.47−0.40+0.45±0.14×10−4 with statistical significance of 5.4σ and 5.6σ, respectively. When combined with measurements of the K1(1270) → K+π−π decays, the absolute branching fractions are determined to be BD0→K11270−e+νe=1.08−0.13−0.10+0.14+0.08±0.21×10−3 and BD+→K¯112700e+νe=1.70−0.23+0.26±0.13±0.35×10−3. The first and second uncertainties are statistical and systematic, respectively, and the third uncertainties originate from the assumed branching fractions of the K1(1270) → Kππ decays

Probing the Inner Disk Emission of the Herbig Ae Stars HD 163296 and HD 190073

This is the author accepted manuscript. The final version is available from American Astronomical Society / IOP Publishing via the DOI in this record.The physical processes occurring within the inner few astronomical units of proto-planetary disks surrounding Herbig Ae stars are crucial to setting the environment in which the outer planet-forming disk evolves and put critical constraints on the processes of accretion and planet migration. We present the most complete published sample of high angular resolution H- and K-band observations of the stars HD 163296 and HD 190073, including 30 previously unpublished nights of observations of the former and 45 nights of the latter with the CHARA long-baseline interferometer, in addition to archival VLTI data. We confirm previous observations suggesting significant near-infrared emission originates within the putative dust evaporation front of HD 163296 and show this is the case for HD 190073 as well. The H- and K-band sizes are the same within (3±3)% for HD 163296 and within (6±10)% for HD 190073. The radial surface brightness profiles for both disks are remarkably Gaussian-like with little or no sign of the sharp edge expected for a dust evaporation front. Coupled with spectral energy distribution analysis, our direct measurements of the stellar flux component at H and K bands suggest that HD 190073 is much younger (<400 kyr) and more massive (~5.6 M⊙) than previously thought, mainly as a consequence of the new Gaia distance (891 pc).JDM and BRS acknowledge support from NSF-AST 1506540 and AA acknowledges support from NSF-AST 1311698. CLD, AK, and SK acknowledge support from the ERC Starting Grant “ImagePlanetFormDiscs” (Grant Agreement No. 639889), STFC Rutherford fellowship/grant (ST/J004030/1, ST/K003445/1) and Philip Leverhulme Prize (PLP2013-110). FB acknowledges support from NSF-AST 1210972 and 1445935. MS acknowledges support by the NASA Origins of Solar Systems grant NAG5-9475, and NASA Astrophysics Data Program contract NNH05CD30C. The CHARA Array is supported by the National Science Foundation under Grant No. AST-1211929, AST-1636624, and AST-1715788. Institutional support has been provided from the GSU College of Arts and Sciences and the GSU Office of the Vice President for Research and Economic Development

Measurement of the e + e − → K S 0 K L 0 π 0 cross sections from s = 2. 000 to 3. 080 GeV

Based on e+e− collision data collected at center-of-mass energies from 2.000 to 3.080 GeV by the BESIII detector at the BEPCII collider, a partial wave analysis is performed for the process e+e− → KS0KL0π0. The results allow the Born cross sections of the process e+e− → KS0KL0π0, as well as its subprocesses e+e− → K∗(892)0K¯0 and K2∗(1430)0K¯0 to be measured. The Born cross sections for e+e− → KS0KL0π0 are consistent with previous measurements by BaBar, but with substantially improved precision. The Born cross section lineshape of the process e+e−K∗(892)0K¯0 is consistent with a vector meson state around 2.2 GeV with a significance of 3.2σ. A Breit-Wigner fit determines its mass as MY = (2164.7 ± 9.1 ± 3.1) MeV/c2 and its width as ΓY = (32.4 ± 21.0 ± 1.8) MeV

Measurement of Born cross section of e + e − → Σ + Σ ¯ − at center-of-mass energies between 3.510 and 4.951 GeV

Using 24.1 fb−1 of e+e− collision data collected with the BESIII detector at the BEPCII collider, the Born cross sections and effective form factors of the e+e−→Σ+Σ¯− reaction are measured. The measurements are performed at center-of-mass energies ranging from 3.510 to 4.951 GeV. No significant evidence for the decay of the charmonium(-like) states, ψ(3770), ψ(4040), ψ(4160), Y(4230), Y(4360), ψ(4415), and Y(4660), into a Σ+Σ¯− final state is observed. Consequently, upper limits for the products of the branching fractions and the electronic partial widths at the 90% confidence level are reported for these decays

Search for ∆S = 2 nonleptonic hyperon decays Ω − → Σ 0 π − and Ω − → nK −

Using (27.12 ± 0.14) × 108ψ(3686) events collected by the BESIII detector at the center-of-mass energy of s = 3.686 GeV, we search for the first time for two nonleptonic hyperon decays that change strangeness by two units, Ω− → Σ0π− and Ω− → nK−. No significant signal is observed. The upper limits on their decay branching fractions are determined to be B(Ω− → Σ0π−) < 5.4 × 10−4 and B(Ω− → nK−) < 2.4 × 10−4 at the 90% confidence level

Observation of ψ (3686) → Ω − K + Ξ ¯ 0 + c. c

Using (27.12 ± 0.14) × 108ψ(3686) events collected with the BESIII detector at BEPCII, the decay of ψ(3686) →Ω−K+Ξ¯0 + c.c. is observed for the first time. The branching fraction of this decay is measured to be Bψ3686→Ω−K+Ξ¯0+c.c. = (2.78 ± 0.40 ± 0.18) × 10−6, where the first uncertainty is statistical and the second is systematic. Possible baryon excited states are searched for in this decay, but no evident intermediate state is observed with the current sample size