Experimental assessment of the acoustic performance of nozzles designed for clean agent fire suppression

Discharge through nozzles used in gas-based fire protection of data centers may generate noise that causes the performance of hard drives to decay considerably; silent nozzles are employed to limit this harmful effect. This work focuses on proposing an experimental methodology to assess the impact of sound emitted by gaseous jets by comparing various nozzles under several operating conditions, together with relating that impact to design parameters. A setup was developed and repeatability of the experiments was evaluated; standard and silent nozzles were tested regarding the discharge of inert gases and halocarbon compounds. The ability of silent nozzles to contain the emitted noise—generally below the 110 dB reference threshold—was proven effective; a relationship between Reynolds number and peak noise level is suggested to support the reported increase in noise maxima as released flow rate increases. Hard drives with lower speed were the most affected. Spectral analysis was conducted, with sound at the higher frequency range causing performance decay even if lower than the acknowledged threshold. Independence of emitted noise from the selected clean agent was also observed in terms of released volumetric flow rate, yet the denser the fluid, the lower the generated noise under the same released mass flow rate

Human Sperm Cryopreservation: Update on Techniques, Effect on DNA Integrity, and Implications for ART

Cryopreservation of human spermatozoa—introduced in the 1960's—has been recognized as an efficient procedure for management of male fertility before therapy for malignant diseases, vasectomy or surgical infertility treatments, to store donor and partner spermatozoa before assisted reproduction treatments and to ensure the recovery of a small number of spermatozoa in severe male factor infertility. Despite the usefulness of it, cryopreservation may lead to deleterious changes of sperm structure and function: while the effects of cryopreservation on cells are well documented, to date there is no agreement in the literature on whether or not cryopreservation affects sperm chromatin integrity or on the use of a unique and functional protocol for the freezing-thawing procedure. Therefore, sperm cryopreservation is an important component of fertility management and much of its successful application seems to affect the reproductive outcome of assisted reproduction technologies (ART): appropriate use of cryoprotectants before and sperm selection technologies after cryopreservation seem to have the greatest impact on preventing DNA fragmentation, thus improving sperm cryosurvival rates

Mucoceles of the oral cavity : a large case series (1994-2008) and a literature review

Objectives: Evaluating data of patients affected by oral mucoceles, examined at the Unit of Oral Medicine and Pathology of the University of Milan between January 1994 and December 2008. Study Design: Concise review on oral mucoceles and analysis of the clinical files of patients who underwent excisional biopsy (patient age, medical history, diagnosis, date and site of the biopsy, histopathological diagnosis and recurrences if any). Results: During the period June 1994-December 2008, 158 mucoceles were observed (93 males and 65 females), with the most frequent site being the lower lip (53%) (p=0.001 by Fisher?s test). The mean age of the patients was 31.9 years, with a peak of occurrence in the first four decades of life (75%). Conclusions: Mucoceles are lesions commonly seen in an oral medicine service, mainly affecting young people and lower lips

Experimental Assessment of the Acoustic Performance of Nozzles Designed for Clean Agent Fire Suppression

Discharge through nozzles used in gas-based fire protection of data centers may generate noise that causes the performance of hard drives to decay considerably; silent nozzles are employed to limit this harmful effect. This work focuses on proposing an experimental methodology to assess the impact of sound emitted by gaseous jets by comparing various nozzles under several operating conditions, together with relating that impact to design parameters. A setup was developed and repeatability of the experiments was evaluated; standard and silent nozzles were tested regarding the discharge of inert gases and halocarbon compounds. The ability of silent nozzles to contain the emitted noise—generally below the 110 dB reference threshold—was proven effective; a relationship between Reynolds number and peak noise level is suggested to support the reported increase in noise maxima as released flow rate increases. Hard drives with lower speed were the most affected. Spectral analysis was conducted, with sound at the higher frequency range causing performance decay even if lower than the acknowledged threshold. Independence of emitted noise from the selected clean agent was also observed in terms of released volumetric flow rate, yet the denser the fluid, the lower the generated noise under the same released mass flow rate