Enhancement of the Deuteron-Fusion Reactions in Metals and its Experimental Implications

Recent measurements of the reaction d(d,p)t in metallic environments at very low energies performed by different experimental groups point to an enhanced electron screening effect. However, the resulting screening energies differ strongly for divers host metals and different experiments. Here, we present new experimental results and investigations of interfering processes in the irradiated targets. These measurements inside metals set special challenges and pitfalls which make them and the data analysis particularly error-prone. There are multi-parameter collateral effects which are crucial for the correct interpretation of the observed experimental yields. They mainly originate from target surface contaminations due to residual gases in the vacuum as well as from inhomogeneities and instabilities in the deuteron density distribution in the targets. In order to address these problems an improved differential analysis method beyond the standard procedures has been implemented. Profound scrutiny of the other experiments demonstrates that the observed unusual changes in the reaction yields are mainly due to deuteron density dynamics simulating the alleged screening energy values. The experimental results are compared with different theoretical models of the electron screening in metals. The Debye-H\"{u}ckel model that has been previously proposed to explain the influence of the electron screening on both nuclear reactions and radioactive decays could be clearly excluded.Comment: 22 pages, 12 figures, REVTeX4, 2-column format. Submitted to Phys. Rev. C; accepte

USP9X stabilizes XIAP to regulate mitotic cell death and chemoresistance in aggressive B-cell lymphoma

The mitotic spindle assembly checkpoint (SAC) maintains genome stability and marks an important target for antineoplastic therapies. However, it has remained unclear how cells execute cell fate decisions under conditions of SAC‐induced mitotic arrest. Here, we identify USP9X as the mitotic deubiquitinase of the X‐linked inhibitor of apoptosis protein (XIAP) and demonstrate that deubiquitylation and stabilization of XIAP by USP9X lead to increased resistance toward mitotic spindle poisons. We find that primary human aggressive B‐cell lymphoma samples exhibit high USP9X expression that correlate with XIAP overexpression. We show that high USP9X/XIAP expression is associated with shorter event‐free survival in patients treated with spindle poison‐containing chemotherapy. Accordingly, aggressive B‐cell lymphoma lines with USP9X and associated XIAP overexpression exhibit increased chemoresistance, reversed by specific inhibition of either USP9X or XIAP. Moreover, knockdown of USP9X or XIAP significantly delays lymphoma development and increases sensitivity to spindle poisons in a murine Eμ‐Myc lymphoma model. Together, we specify the USP9X–XIAP axis as a regulator of the mitotic cell fate decision and propose that USP9X and XIAP are potential prognostic biomarkers and therapeutic targets in aggressive B‐cell lymphoma

Wibroizolacja dróg kolejowych oraz rozkład energetyczny oddziaływań dynamicznych na środowisko

This research presents the concept of vibroisolation of railroad lines by example of one of the solutions designed by the author, and contains comparison of distribution of energy carried out to the subgrade of traditional and vibroisolated railroad tracks.W pracy przedstawiono koncepcję wibroizolacji przejazdu kolejowo-drogowego, rozwiązania wibroizolowanego przejazdu i jego wpływ na oddziaływania dynamiczne na otoczenie na podstawie rozkładu energetycznego

Influence of vibration isolation system of tramway subgrades on vibration in the Cracow Philharmonic

W artykule omówiony zostało zagadnienie ograniczenia drgań w Sali Koncertowej Filharmonii Krakowskiej w oparciu o zastosowanie konstrukcji wibroizolowanego torowiska tramwajowego. Wyznaczono skuteczność zastosowanego systemu wibroizolacji w oparciu o przeprowadzone pomiary i oceniono wpływ oddziaływań dynamicznych od ruchu tramwajowego po jego zastosowaniu na poziom drgań w Sali Koncertowej.The article discussed the issue of limiting vibration in the Concert Hall of the Krakow Philharmonic, based on the use of vibroisolated tramway subgrade. Determination of the effectiveness of the applied vibration isolation system based on the measurements carried out are presented in the paper. Evaluation the impact of dynamic interactions of the tram traffic after using vibroisolated tramway subgrade on the level of vibration in the Concert Hall is also presented in the article

Diagnostics of mechanical parameters NiTi material

Stopy wykazujące się efektem pamięci kształtu, do których należy stop NiTi, wykazują w stanie martenzytycznym bardzo dobre własności tłumienia drgań. Jednak w celu określenia ich rzeczywistej przydatności do zastosowania w maszynach i urządzeniach wibracyjnych oraz złożonych układach wibroizolacji należy przeprowadzić diagnostykę statyczno-dynamiczną własności fizyko - mechanicznych takich jak: modułu sprężystości podłużnej E, sztywności oraz miary tłumienia. Diagnostykę własności fizyko - mechanicznych przeprowadzono dla drutu NiTi o średnicy d=1 mm i o stężeniu masowym 53-57% niklu w komorze temperaturowej, dla temperatur 20, 35, 50 i 60°C i w zakresie obciążeń 0,15 - 0,65 kN. Diagnostyka obejmowała między innymi wyznaczenie modułu Young'a, współczynnika sprężystości (statycznego i dynamicznego), współczynnika tłumienia (statycznego i dynamicznego). W artykule tym zaprezentowano wyniki przeprowadzonych badań.Preventing the process of vibration spreading or the process of controlling vibrations from technological point of view involves mainly applying the elastic elements, more and more often including shape-memory materials, also by some authors referred to as intelligent materials. Diagnostics of NiTi element included Young's modulus,elasticity coefficient (static and dynamic), damping coefficient (static and dynamic). The diagnostics were carried out on NiTi wire of a diameter d=0.,001 m, (in a constant-temperature chamber) for temperatures of 20, 35, 50 and 60°C were carried out with loads 0,15 - 0,65 kN. Diagnostics of mechanical parameters The results of the conducted tests are enclosed in this article