468 research outputs found

    Find Your Creative Side

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    Find Your Creative Sidehttps://source.sheridancollege.ca/fhass_infographics_creative_thinking/1000/thumbnail.jp

    Das Projekt „Corpus Coranicum“ als Ausdruck neuer Koranexegese

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    Die vorliegende Arbeit nimmt beide Aspekte, nämlich Neuwirths Arbeiten und das Corpus Coranicum, in den Blick. Ein wesentliches Ziel dieser Arbeit ist es, durch die Darstellung der von Neuwirth entwickelten bzw. bearbeiteten Ideen und Theorien sowie des Corpus der Frage nach der Art des Verhältnisses zwischen Neuwirths Werken und dem Corpus Coranicum nachzugehen

    Contrastive analysis of Orwell’s Newspeak in two Spanish translations: how neologisms are rendered in two different Spanish political settings

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    English-Spanish translation acts as an essential vehicle across several countries in order to accurately convey the meaning and ideas of certain art pieces. This purpose is harder to achieve when the piece selected is innovative. Such is the case of the translations produced of Orwell’s 1984. In this project, two Spanish translations of Orwell’s invented language, the Newspeak, in 1984 are analyzed as each was produced in two different political settings of Spain (i.e., in 1952 during Franco’s dictatorship and in 2013 under a democratic system). The contrastive analysis is focused on how the two translators, Vázquez Zamora and Temprano García, respectively, render in Spanish the socio-political neologisms found in the Newspeak. The results show that Vázquez Zamora mostly sticks to the literality in his translations whereas Temprano García manifests more creativeness. The interpretation of these results leads to the roles of two mutually influential factors: i) the different social-political environments both translators lived under in their respective timelines, which could imply different degrees in the limitation of each translator’s creativity; and ii) a more intrinsic motivation, i.e., the literary style each translator reflects in their works.La traducción inglés-español actúa como vehículo imprescindible en varios países con el fin de transmitir con precisión el significado y las ideas de ciertas obras de arte. Este propósito es más difícil de llevar a cabo cuando el trabajo seleccionado es innovador. Tal es el caso de las traducciones que se realizaron de 1984 de Orwell. En este proyecto, se analizan dos traducciones al español del lenguaje inventado de Orwell, la Neolengua, en 1984, ya que cada una se produjo en dos entornos políticos diferentes de España (esto es, en 1952 durante la dictadura de Franco y en 2013 bajo un sistema democrático). El análisis contrastivo se centra en cómo los dos traductores, Vázquez Zamora y Temprano García, respectivamente, interpretan en español los neologismos sociopolíticos encontrados en la Neolengua. Los resultados muestran que Vázquez Zamora se apega principalmente a la literalidad en sus traducciones, mientras que Temprano García manifiesta más creatividad. La interpretación de estos resultados lleva al papel de dos factores mutuamente influyentes: i) los diferentes entornos sociopolíticos bajo los que ambos traductores vivieron en sus respectivas líneas de tiempo, lo que podría implicar diferentes grados en la limitación de la creatividad de cada traductor; y ii) una motivación más intrínseca, es decir, el estilo literario que cada traductor refleja en sus obras.Departamento de Filología InglesaGrado en Estudios Inglese

    Immunohistochemical expression of p21 in normal tissues of salivary gland, pleomorphic adenoma and carcinoma ex pleomorphic adenoma (undifferentiated and adenocarcinoma types)

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    Objective: Our study aimed to characterize alteration in the immunohistochemical expression of p21 in normal tissue of the salivary gland surrounding pleomorphic adenoma, the tumor cells of pleomorphic adenomas, and carcinoma arising in pleomorphic adenoma. Study design: A selected series of 29 cases of pleomorphic adenomas, and 27 cases of carcinoma ex-pleomorphic adenoma (undifferentiated and adenocarcinoma types) were examined. Results: The results showed that p21 expression was negative in the most components of normal tissue of the salivary gland surrounding pleomorphic adenoma, 24 cases out of 29 of the non tumour duct cells (82.8%), and 28 (96.6%) cases out of 29 of the acinar cells shows negative p21 expression. P21 expression in pleomorphic adenomas shows that 2 cases out of 29 (6.9%) strongly expressed in the duct cells. p21 was strongly expressed in carcinoma cells in 9 (33.3%) cases out of 27. Conclusion: Our data suggest that the strong nuclear staining as an indicator for altered p21, then the alteration of p21 expression would increase from pleomorphic adenoma to carcinoma arising in pleomorphic adenomas (6.9% versus 33.3%)

    Immunohistochemical expression of oestrogens and progesterone receptors in carcinoma ex pleomorphic adenoma- undifferentiated and adenocarcinoma types

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    Cancer of the salivary gland is one of the common cancers in the head and the neck regions. This type of cancer develops in the minor and the major salivary glands, and it sometimes metastasizes to other organs, particularly the lung. Morphologic mimicry and similarity in the expression of steroid hormone receptors between salivary gland tumors and breast tumors are well-known phenomena and are occasionally debated in the field of surgical pathology. The expression of sex hormone receptors in some tumors suggests a role for these receptors in tumor pathogenesis and therapy. Previous studies of the expression of estrogens and progesterone receptors in salivary gland tumors have reported conflicting results. Objective: Our study aimed to characterize alteration in the immunohistochemical expression of estrogens receptor and progesterone receptor in the tumor cells of carcinoma arising in pleomorphic adenoma. Study design: 27 cases of carcinoma arising in pleomorphic adenoma (undifferentiated and adenocarcinoma types) were examined. Results: The results showed that 27 (100 %) of 27 cases had negative nuclear staining for either estrogens or progesterone receptors. Conclusion: Our data suggest that carcinomas arising in pleomorphic adenoma were not dependent on endocrine function

    Immunohistochemical Expression of p53 in Pleomorphic Adenoma and Carcinoma Ex Pleomorphic Adenoma

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    Context. Immunohistochemical stains for p53 are used as a diagnostic marker associated with malignancy in several histologic types of salivary gland tumors. This marker may be useful in differentiating pleomorphic adenoma (PA) from carcinoma ex pleomorphic adenoma (CPA), as these tumors are often difficult to distinguish on the basis of morphology alone. Objective. to evaluate whatever inactivation of tumor suppressor gene (p53) increases with the tumor progression from normal salivary tissue to PA and eventually CPA. Design. Paraffin blocks of 29 cases of PA, which were surrounded by normal parotid gland, and 27 cases of carcinoma ex pleomorphic adenoma were retrieved and validated. In all cases of carcinoma ex pleomorphic adenoma, a PA “ghost” was identified, and the malignant element was either undifferentiated carcinoma or adenocarcinoma. Results. The results showed negative nuclear expression of P53 in normal parotid gland. Nuclear P53 was expressed strongly in 6/29 (20.7%) pleomorphic salivary adenoma and 10/27 (37%) carcinoma ex pleomorphic adenoma. Conclusion. Our data suggest that inactivation of p53 may play an important role in the evolution of pleomorphic salivary adenoma and carcinoma ex pleomorphic adenoma

    An immunohistochemical study of the distribution of p 16 protein in oral mucosa in smokers, non-smokers and in frictional keratosis

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    Objective: Our study aimed to characterize alteration in the immunohistochemical p16 expression in normal oral mucosa and non-neoplastic hyperproliferative disorders (i.e. frictional keratosis and mucosa from smokers). Study design: 43 specimen of oral mucosa were examined using immunohistochemistry. Results: In normal mucosa, there was strong positive nuclear staining in a proportion of fibroblasts and endothelial cells in the lamina propria, with variable expression in nuclei of the epithelial layer. However, when the patient?s tobacco smoking was examined, p16 nuclear staining in oral epithelium was seen in 4/20 (20%) of smokers and 0/23 (0%) of non-smokers. In every case of frictional keratosis (n=11), there was strong nuclear staining of some basal and supra-basal cells. In addition, there was strong nuclear staining of parakeratinizing squamous in a band above the spinous layer. In clinically normal oral epithelium of smokers and in frictional keratosis, basal and supra-basal cells expressed strong p16 nuclear staining which was absent in the control tissue examined. Conclusion: Our data suggest that p16 expression may be involved in the long-term loss of proliferation in cell senescence of oral mucosa

    Hepatobiliary scintigraphy as a diagnostic modality for gastroparesis of the bypassed stomach after gastric bypass for morbid obesity.

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    After Roux-en-Y gastric bypass (RYGBP), the excluded gastric remnant represents a challenge for the surgeon. Many diseases are reported to take place in that remnant, such as cancer, gastritis, and ulcer. On the other hand, diagnosing these pathological changes requires invasive intervention. We report the use of a noninvasive study to diagnose pathology in the bypassed stomach

    Consumo de inhibidores de la bomba de protones (IBP) y riesgos asociados a la alteración de la absorción del calcio. Una revisión bibliográfica

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    El consumo de los Inhibidores de la Bomba de Protones se ha convertido en uno de las más frecuentes en la población, incluso sin prescripción, al estar considerado de uso primario en el tratamiento de la acidez o la dispepsia. Tanto es así que en medicina se ha comenzado a investigar sus posibles efectos adversos en el organismo humano a posteriori, observando en múltiples estudios realizados, una disminución de la capacidad del mismo en la absorción del calcio. Esto se observa, en mayor proporción, en las mujeres de mayor edad debido a la disminución en las mismas del factor protector que son los estrógenos. En nuestro trabajo se ha seleccionado una serie de artículos de características distintas, los cuales corroboran esta alteración. De acuerdo a Ngamruengphong S, Leontiadis GI, Radhi S et al, en los usuarios de PPI, en comparación con los usuarios no consumidores, la OR para la fractura de cadera (n = 9) fue de 1.25 (intervalo de confianza [IC] del 95% = 1.14-1.37). La OR para la fractura vertebral (n = 4) fue de 1,50 (IC del 95% = 1,32-1,72) y para la fractura de muñeca / antebrazo (n = 3) fue de 1,09 (IC del 95% = 0,95-1,24). Se describe como causante principal de estas alteraciones un complejo mecanismo bioquímico provocado, en primer plano, por una hipergastrinemia y una supresión de los ácidos gástricos que van a inducir, en último término, ese desequilibrio en el calcio. Se deben, por tanto, prescribir estos medicamentos solo cuando sea estrictamente necesario y, en el caso de que la duración de los mismos supere un año, aportar calcio exógeno como suplementos para favorecer una compensación metabólica del mineral.Grado en Nutrición Humana y Dietétic

    A survey of dentists? practice in the restoration of the shortened dental arch

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    Objectives: The aim of this survey was to determine how a sample of dentists working in general dental practice in the UK sought to restore the mouths of patients who had shortened dental arches (SDAs). Study design: A survey was conducted over a period of six months on four commercial dental laboratories. Cases of SDAs comprising the anterior teeth and 2 to 4 premolars were examined; dental prescriptions were scrutinized and a special data collection form was completed accordingly. Results: A total of 140 SDA cases were examined. Most of these cases were for mandibular SDAs (88.6%). Of the recorded SDA cases, 67.2% were restored by cobalt-chromium based removable partial dentures (RPD); 25.7% were extended by acrylic-resin based RPDs; implants were provided to restore 8 SDA cases (5.7%); and only two SDA cases (1.4%) were extended by cantilevered fixed bridges. Neither the gender of the patient ([Chi (2)= 4.19, p>0.05) nor the length of the SDA ([Chi (2) = 6.51, p>0.05) influenced the choice of prosthesis to be implemented. Conclusions: It would appear from the results of this survey that among the different restorative treatment options for SDA, the RPD was the most popular treatment option for dentists surveyed in this UK study. Extending the SDA by either an implant-supported prosthesis or cantilevered fixed bridges did not appear to be a popular choice of treatment
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