384 research outputs found

    Used infant mattresses and sudden infant death syndrome in Scotland: case-control study

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    <P>OBJECTIVE: To examine the proposition that a used infant mattress is associated with an increased risk of sudden infant death syndrome. DESIGN: Case-control study. SETTING: Scotland (population 5.1 million, with about 53 000 births a year).</P> <P>PARTICIPANTS: 131 infants who died of sudden infant death syndrome between 1 January 1996 and 31 May 2000 and 278 age, season, and obstetric unit matched control infants.</P> <P>MAIN OUTCOME MEASURES: Routine use of an infant mattress previously used by another child and place of last sleep.</P> <P>RESULTS: Routine use of an infant mattress previously used by another child was significantly associated with an increased risk of sudden infant death syndrome (multivariate odds ratio 3.07, 95% confidence interval 1.51 to 6.22). Use of a used infant mattress for last sleep was also associated with increased risk (6.10, 2.31 to 16.12). The association was significantly stronger if the mattress was from another home (4.78, 2.08 to 11.0) than if it was from the same home (1.64, 0.64 to 4.2).</P> <P>CONCLUSION: A valid significant association exists between use of a used infant mattress and an increased risk of sudden infant death syndrome, particularly if the mattress is from another home. Insufficient evidence is available to judge whether this relation is cause and effect.</P&gt

    Problems involved in the measurement of imagery in seventh and eighth graders.

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    Thesis (Ed.M.)--Boston Universit

    Observations of Detailed Structure in the Solar Wind at 1 AU with STEREO/HI-2

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    Heliospheric imagers offer the promise of remote sensing of large-scale structures present in the solar wind. The STEREO/HI-2 imagers, in particular, offer high resolution, very low noise observations of the inner heliosphere but have not yet been exploited to their full potential. This is in part because the signal of interest, Thomson scattered sunlight from free electrons, is ~1000 times fainter than the background visual field in the images, making background subtraction challenging. We have developed a procedure for separating the Thomson-scattered signal from the other background/foreground sources in the HI-2 data. Using only the Level 1 data from STEREO/HI-2, we are able to generate calibrated imaging data of the solar wind with sensitivity of a few times 1e-17 Bsun, compared to the background signal of a few times 1e-13 Bsun. These images reveal detailed spatial structure in CMEs and the solar wind at projected solar distances in excess of 1 AU, at the instrumental motion-blur resolution limit of 1-3 degree. CME features visible in the newly reprocessed data from December 2008 include leading-edge pileup, interior voids, filamentary structure, and rear cusps. "Quiet" solar wind features include V shaped structure centered on the heliospheric current sheet, plasmoids, and "puffs" that correspond to the density fluctuations observed in-situ. We compare many of these structures with in-situ features detected near 1 AU. The reprocessed data demonstrate that it is possible to perform detailed structural analyses of heliospheric features with visible light imagery, at distances from the Sun of at least 1 AU.Comment: Accepted by Astrophysical Journa

    The Thomson Surface. II. Polarization

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    The solar corona and heliosphere are visible via sunlight that is Thomson-scattered off of free electrons, yielding a radiance against the celestial sphere. In this second part of a three-article series, we discuss linear polarization of this scattered light parallel and perpendicular to the plane of scatter in the context of heliopheric imaging far from the Sun. The difference between these two radiances, (pB), varies quite differently with scattering angle, compared to the sum that would be detected in unpolarized light (B). The difference between these two quantities has long been used in a coronagraphic context for background subtraction and to extract some three-dimensional information about the corona; we explore how these effects differ in the wider-field heliospheric imaging case where small-angle approximations do not apply. We develop an appropriately-simplified theory of polarized Thomson scattering in the heliosphere, discuss signal-to-noise considerations, invert the scattering equations analytically to solve the three dimensional object location problem for small objects, discuss exploiting polarization for background subtraction, and generate simple forward models of several classes of heliospheric feature. We conclude that pB measurements of heliospheric material are much more localized to the Thomson surface than are B measurements, that the ratio pB/B can be used to track solar wind features in three dimensions for scientific and space weather applications better in the heliosphere than corona; and that, by providing an independent measurement of background signal, pB measurements may be used to reduce the effect of background radiances including the stably polarized zodiacal light.Comment: v2: text as accepted by APJ (before proofs); formatted with emulateapj.cl

    Tracking Streamer Blobs Into the Heliosphere

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    In this paper, we use coronal and heliospheric images from the STEREO spacecraft to track streamer blobs into the heliosphere and to observe them being swept up and compressed by the fast wind from low-latitude coronal holes. From an analysis of their elongation/time tracks, we discover a 'locus of enhanced visibility' where neighboring blobs pass each other along the line of sight and their corotating spiral is seen edge on. The detailed shape of this locus accounts for a variety of east-west asymmetries and allows us to recognize the spiral of blobs by its signatures in the STEREO images: In the eastern view from STEREO-A, the leading edge of the spiral is visible as a moving wavefront where foreground ejections overtake background ejections against the sky and then fade. In the western view from STEREO-B, the leading edge is only visible close to the Sun-spacecraft line where the radial path of ejections nearly coincides with the line of sight. In this case, we can track large-scale waves continuously back to the lower corona and see that they originate as face-on blobs.Comment: 15 pages plus 11 figures; figure 6 shows the 'locus of enhanced visibility', which we call 'the bean'. (accepted by ApJ 4/02/2010

    Pharmaceuticals in soils of lower income countries: Physico-chemical fate and risks from wastewater irrigation.

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    Population growth, increasing affluence, and greater access to medicines have led to an increase in active pharmaceutical ingredients (APIs) entering sewerage networks. In areas with high wastewater reuse, residual quantities of APIs may enter soils via irrigation with treated, partially treated, or untreated wastewater and sludge. Wastewater used for irrigation is currently not included in chemical environmental risk assessments and requires further consideration in areas with high water reuse. This study critically assesses the contemporary understanding of the occurrence and fate of APIs in soils of low and lower-middle income countries (LLMIC) in order to contribute to the development of risk assessments for APIs in LLMIC. The physico-chemical properties of APIs and soils vary greatly globally, impacting on API fate, bioaccumulation and toxicity. The impact of pH, clay and organic matter on the fate of organic ionisable compounds is discussed in detail. This study highlights the occurrence and the partitioning and degradation coefficients for APIs in soil:porewater systems, API usage data in LLMICS and removal rates (where used) within sewage treatment plants as key areas where data are required in order to inform robust environmental risk assessment methodologies

    The cessation in pregnancy incentives trial (CPIT): study protocol for a randomized controlled trial

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    Background: Seventy percent of women in Scotland have at least one baby, making pregnancy an opportunity to help most young women quit smoking before their own health is irreparably compromised. By quitting during pregnancy their infants will be protected from miscarriage and still birth as well as low birth weight, asthma, attention deficit disorder and adult cardiovascular disease. In the UK, the NICE guidelines: 'How to stop smoking in pregnancy and following childbirth' (June 2010) highlighted that little evidence exists in the literature to confirm the efficacy of financial incentives to help pregnant smokers to quit. Its first research recommendation was to determine: Within a UK context, are incentives an acceptable, effective and cost-effective way to help pregnant women who smoke to quit? <p/>Design and Methods: This study is a phase II exploratory individually randomised controlled trial comparing standard care for pregnant smokers with standard care plus the additional offer of financial voucher incentives to engage with specialist cessation services and/or to quit smoking during pregnancy. Participants (n=600) will be pregnant smokers identified at maternity booking who when contacted by specialist cessation services agree to having their details passed to the NHS Smokefree Pregnancy Study Helpline to discuss the trial. The NHS Smokefree Pregnancy Study Helpline will be responsible for telephone consent and follow-up in late pregnancy. The primary outcome will be self reported smoking in late pregnancy verified by cotinine measurement. An economic evaluation will refine cost data collection and assess potential cost-effectiveness while qualitative research interviews with clients and health professionals will assess the level of acceptance of this form of incentive payment. Research questions What is the likely therapeutic efficacy? Are incentives potentially cost-effective? Is individual randomisation an efficient trial design without introducing outcome bias? Can incentives be introduced in a way that is feasible and acceptable? <p/>Discussion: This phase II trial will establish a workable design to reduce the risks associated with a future definitive phase III multicentre randomised controlled trial and establish a framework to assess the costs and benefits of financial incentives to help pregnant smokers to quit

    Temporal variability in dynamic and colloidal metal fractions determined by high resolution in situ measurements in a UK estuary

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    In recent environmental legislation, such as the Water Framework Directive in the European Union (WFD, 2000/60/EC), the importance of metal speciation and biological availability is acknowledged, although analytical challenges remain. In this study, the Voltammetric In situ Profiler (VIP) was used for high temporal resolution in situ metal speciation measurements in estuarine waters. This instrument simultaneously determines Cd, Cu and Pb species within a size range (ca<4. nm) that is highly relevant for uptake by organisms. The colloidal metal fraction can be quantified through a combination of VIP measurements and analyses of total dissolved metal concentrations.VIP systems were deployed over tidal cycles in a seasonal study of metal speciation in the Fal Estuary, southwest England. Total dissolved concentrations were 4.97-315. nM Cu, 0.13-8.53. nM Cd and 0.35-5.75. nM Pb. High proportions of Pb (77 ± 17) and Cu (60 ± 25) were present as colloids, which constituted a less important fraction for Cd (37 ± 30). The study elucidated variations in the potentially toxic metal fraction related to river flow, complexation by organic ligands and exchanges between dissolved and colloidal phases and the sediment. Based on published toxicity data, the bioavailable Cu concentrations (1.7-190. nM) in this estuary are likely to severely compromise the ecosystem structure and functioning with respect to species diversity and recruitment of juveniles. The study illustrates the importance of in situ speciation studies at high resolution in pursuit of a better understanding of metal (bio)geochemistry in dynamic coastal systems. © 2011 Elsevier Ltd
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