393 research outputs found
Compact Printed CPW-fed UWB antenna with SRR and Quarter wavelength slot with dual band-notched characteristic
Volume 2 Issue 3 (March 2014
ARTYCUL: A Privacy-Preserving ML-Driven Framework to Determine the Popularity of a Cultural Exhibit on Display.
We present ARTYCUL (ARTifact popularitY for CULtural heritage), a machine learning(ML)-based framework that graphically represents the footfall around an artifact on display at a museum or a heritage site. The driving factor of this framework was the fact that the presence of security cameras has become universal, including at sites of cultural heritage. ARTYCUL used the video streams of closed-circuit televisions (CCTV) cameras installed in such premises to detect human figures, and their coordinates with respect to the camera frames were used to visualize the density of visitors around the specific display items. Such a framework that can display the popularity of artifacts would aid the curators towards a more optimal organization. Moreover, it could also help to gauge if a certain display item were neglected due to incorrect placement. While items of similar interest can be placed in vicinity of each other, an online recommendation system may also use the reputation of an artifact to catch the eye of the visitors. Artificial intelligence-based solutions are well suited for analysis of internet of things (IoT) traffic due to the inherent veracity and volatile nature of the transmissions. The work done for the development of ARTYCUL provided a deeper insight into the avenues for applications of IoT technology to the cultural heritage domain, and suitability of ML to process real-time data at a fast pace. While we also observed common issues that hinder the utilization of IoT in the cultural domain, the proposed framework was designed keeping in mind the same obstacles and a preference for backward compatibility
Extrahepatic undifferentiated embryonal sarcoma, cytology as an accurate method for early diagnosis: an extremely rare case report in an Indian child
Undifferentiated embryonal sarcoma has been described in the liver, a rare malignant mesenchymal neoplasm, that occurs primarily in children and teenagers. Approximately 260 cases have been reported arising in the liver since 1978 when this disease was first described. Its pathogenesis is still obscure. Authors presented a case of extrahepatic undifferentiated embryonal sarcoma in a 9-year-old female presenting with upper abdominal dull pain. Ultrasound and CT Scan showed normal liver architecture, with liver pushed upwards due to compression by tumor arising in the retroperitoneum. To the best of our knowledge, this is first case of extrahepatic undifferentiated embryonal sarcoma diagnosed on cytomorphology and confirmed by histopathology and immunohistochemistry markers
Oligomerization of the human immunodeficiency virus type 1 (HIV-1) Vpu protein β a genetic, biochemical and biophysical analysis
<p>Abstract</p> <p>Background</p> <p>The human immunodeficiency virus type 1(HIV-1) is a complex retrovirus and the causative agent of acquired immunodeficiency syndrome (AIDS). The HIV-1 Vpu protein is an oligomeric integral membrane protein essential for particle release, viral load and CD4 degradation. <it>In silico </it>models show Vpu to form pentamers with an ion channel activity.</p> <p>Results</p> <p>Using Vpu proteins from a primary subtype C and the pNL4-3 subtype B isolates of HIV-1, we show oligomerization of the full-length protein as well as its transmembrane (TM) domain by genetic, biochemical and biophysical methods. We also provide direct evidence of the presence of Vpu pentamers in a stable equilibrium with its monomers <it>in vitro</it>. This was also true for the TM domain of Vpu. Confocal microscopy localized Vpu to the endoplasmic reticulum and Golgi regions of the cell, as well as to post-Golgi vesicles. In fluorescence resonance energy transfer (FRET) experiments in live cells we show that Vpu oligomerizes in what appears to be either the Golgi region or intracellular vesicles, but not in the ER.</p> <p>Conclusion</p> <p>We provide here direct evidence that the TM domain, is critical for Vpu oligomerization and the most favourable channel assembly is a pentamer. The Vpu oligomerization appears to be either the Golgi region or intracellular vesicles, but not in the ER.</p
ΠΠΎΠ½ΡΠ΅ΠΏΡΠΈΡ Π±Π°Π·ΠΎΠ²ΠΎΠ³ΠΎ Π½Π°ΡΠΈΠΎΠ½Π°Π»ΡΠ½ΠΎ-ΠΎΡΠΈΠ΅Π½ΡΠΈΡΠΎΠ²Π°Π½Π½ΠΎΠ³ΠΎ ΡΡΠ΅Π±Π½ΠΈΠΊΠ° ΠΏΡΠ°ΠΊΡΠΈΡΠ΅ΡΠΊΠΎΠ³ΠΎ ΠΊΡΡΡΠ° ΡΡΡΡΠΊΠΎΠ³ΠΎ ΡΠ·ΡΠΊΠ° Π΄Π»Ρ ΡΠΊΠΎΠ» ΠΠ½Π΄ΠΈΠΈ
In this article conception of modern textbook for students learning Russian out of the language environment is suggested. To achieve this aim it was necessary to solve the following problems: to reveal students' communicative needs, which influence the amount and level of their communicative competence; to give systematic description of the components of structure of the textbook on practical course of Russian language; to analyze the language and communicative components of the manual content and its communicative structure; to elaborate the structure of the manual units, to characterize main teaching technologies realized.Π ΡΡΠ°ΡΡΠ΅ ΠΎΠΏΠΈΡΡΠ²Π°Π΅ΡΡΡ ΠΊΠΎΠ½ΡΠ΅ΠΏΡΠΈΡ ΡΠΎΠ²ΡΠ΅ΠΌΠ΅Π½Π½ΠΎΠ³ΠΎ ΡΠΊΠΎΠ»ΡΠ½ΠΎΠ³ΠΎ ΡΡΠ΅Π±Π½ΠΈΠΊΠ°, ΠΏΡΠ΅Π΄Π½Π°Π·Π½Π°ΡΠ΅Π½Π½ΠΎΠ³ΠΎ Π΄Π»Ρ ΠΎΠ²Π»Π°Π΄Π΅Π½ΠΈΡ ΡΡΡΡΠΊΠΈΠΌ ΡΠ·ΡΠΊΠΎΠΌ Π²Π½Π΅ ΡΠ·ΡΠΊΠΎΠ²ΠΎΠΉ ΡΡΠ΅Π΄Ρ. Π‘ ΡΡΠΎΠΉ ΡΠ΅Π»ΡΡ ΠΏΠΎΡΡΠ΅Π±ΠΎΠ²Π°Π»ΠΎΡΡ ΠΏΠΎΡΠ»Π΅Π΄ΠΎΠ²Π°ΡΠ΅Π»ΡΠ½ΠΎ ΡΠ΅ΡΠ°ΡΡ ΡΠ»Π΅Π΄ΡΡΡΠΈΠ΅ Π·Π°Π΄Π°ΡΠΈ: Π²ΡΡΠ²ΠΈΡΡ ΠΊΠΎΠΌΠΌΡΠ½ΠΈΠΊΠ°ΡΠΈΠ²Π½ΡΠ΅ ΠΏΠΎΡΡΠ΅Π±Π½ΠΎΡΡΠΈ ΠΎΠ±ΡΡΠ°ΡΡΠΈΡ
ΡΡ, Π²Π»ΠΈΡΡΡΠΈΠ΅ Π½Π° ΠΎΠ±ΡΠ΅ΠΌ ΠΈ ΡΡΠΎΠ²Π΅Π½Ρ ΠΈΡ
ΠΊΠΎΠΌΠΌΡΠ½ΠΈΠΊΠ°ΡΠΈΠ²Π½ΠΎΠΉ ΠΊΠΎΠΌΠΏΠ΅ΡΠ΅Π½ΡΠΈΠΈ; Π΄Π°ΡΡ ΡΠ΅Π»ΠΎΡΡΠ½ΠΎΠ΅ ΡΠΈΡΡΠ΅ΠΌΠ½ΠΎΠ΅ ΠΎΠΏΠΈΡΠ°Π½ΠΈΠ΅ ΡΡΡΡΠΊΡΡΡΠ½ΡΡ
ΠΊΠΎΠΌΠΏΠΎΠ½Π΅Π½ΡΠΎΠ² ΡΡΠ΅Π±Π½ΠΈΠΊΠ° ΠΏΡΠ°ΠΊΡΠΈΡΠ΅ΡΠΊΠΎΠ³ΠΎ ΠΊΡΡΡΠ° ΡΡΡΡΠΊΠΎΠ³ΠΎ ΡΠ·ΡΠΊΠ° ΠΊΠ°ΠΊ ΠΈΠ½ΠΎΡΡΡΠ°Π½Π½ΠΎΠ³ΠΎ Π΄Π»Ρ ΡΠΊΠΎΠ»ΡΠ½ΠΈΠΊΠΎΠ² ΡΡΠ΅Π΄Π½Π΅ΠΉ ΡΡΡΠΏΠ΅Π½ΠΈ; ΠΎΠΏΠΈΡΠ°ΡΡ ΡΠ·ΡΠΊΠΎΠ²ΡΠ΅ ΠΈ ΡΠ΅ΡΠ΅Π²ΡΠ΅ ΠΊΠΎΠΌΠΏΠΎΠ½Π΅Π½ΡΡ ΡΠΎΠ΄Π΅ΡΠΆΠ°Π½ΠΈΡ ΡΡΠ΅Π±Π½ΠΈΠΊΠ°, Π΅Π³ΠΎ ΠΊΠΎΠΌΠΌΡΠ½ΠΈΠΊΠ°ΡΠΈΠ²Π½ΡΡ ΠΎΡΠ³Π°Π½ΠΈΠ·Π°ΡΠΈΡ; ΡΠ°ΡΡΠΌΠΎΡΡΠ΅ΡΡ Π²ΠΎΠΏΡΠΎΡ ΠΎ ΡΡΡΡΠΊΡΡΡΠ΅ ΡΡΠΎΠΊΠΎΠ² ΡΡΠ΅Π±Π½ΠΈΠΊΠ°; ΠΈΠ·Π»ΠΎΠΆΠΈΡΡ ΠΎΡΠ½ΠΎΠ²Π½ΡΠ΅ ΡΠ΅Π°Π»ΠΈΠ·ΡΠ΅ΠΌΡΠ΅ Π² Π½Π΅ΠΌ ΡΠ΅Ρ
Π½ΠΎΠ»ΠΎΠ³ΠΈΠΈ ΠΎΠ±ΡΡΠ΅Π½ΠΈΡ
Prospective evaluation of a primary care referral pathway for patients with non-alcoholic fatty liver disease.
BACKGROUND & AIMS: We aimed to develop and evaluate a pathway for management of patients with non-alcoholic fatty liver disease (NAFLD) using blood tests to stratify patients in primary care to improve detection of cases of advanced fibrosis and cirrhosis, and avoid unnecessary referrals to secondary care. METHODS: This was a prospective longitudinal cohort study with before-and-after analysis and comparison to unexposed controls. We used a two-step algorithm combining the use of FIB-4 followed by the ELF test if required RESULTS: In total, 3,012 patients were analysed. Use of the pathway detected 5 times more cases of advanced fibrosis (Kleiner F3) and cirrhosis (OR=5.18; 95%CI=2.97 to 9.04; p<0.0001). Unnecessary referrals from primary care to secondary care fell by 81% (OR=0.193; 95%CI 0.111 to 0.337; p<0.0001). Three times more cases of cirrhosis were diagnosed (OR=3.14; 95%CI=1.57 to 24; p=0.00011). Although it was used for only 48% of referrals, significant benefits were observed across all referrals from the practices exposed to the pathway. Unnecessary referrals fell by 77% (OR=0.23; 95% CI=0.658 to 0.082; p=0.006) with a 4-fold improvement in detection of cases of advanced fibrosis and cirrhosis (OR=4.32; 95% CI=1.52 to 12.25; p=0.006). Compared to referrals made before introduction of the pathway, unnecessary referrals fell from 79/83 referrals (95.2%) to 107/152 (70.4%) representing an 88% reduction in unnecessary referrals when the pathway was followed (OR=0.12; 95%CI=0.042 to 0.349; p<0.0001). CONCLUSIONS: The use of non-invasive blood tests for liver fibrosis to stratify patients with NAFLD improves the detection of cases of advanced fibrosis and cirrhosis and reduces unnecessary referrals to secondary care of patients with lesser degrees of liver fibrosis. This strategy improves resource use and benefits patients. LAY SUMMARY: Non-alcoholic fatty liver disease effects up to 30% of the population but only a minority of cases develop liver disease. Our study has shown that established blood tests can be used in primary care to stratify patients with fatty liver disease to reduce unnecessary referrals by 80% and improve the detection of cases of advanced fibrosis 5 fold and cirrhosis 3 fold
Role of Salicylic Acid in Combating Heat Stress in Plants : Insights into Modulation of Vital Processes
Peer reviewe
Large-scale IPM validation in whitefly (Bemisia tabaci)-prone cotton (Gossypium spp.) fields adjoining kinnow orchards
Whitefly [Bemisia tabaci (Gen)] is a serious sucking pest of cotton in the north zone of India. Cotton (Gossypium
spp.) fields adjoining kinnow orchards used to have a quite higher incidence of whiteflies compared to the fields
away from orchards. Therefore, the study was carried out at ICAR-National Centre for Integrated Pest Management,
New Delhi during 2017β19 to implement integrated pest management (IPM) validation trial in cotton fields located
adjoining the kinnow orchards in the village Nihalkhera of district Fazilka, Punjab in farmersβ participatory (FP). The
IPM strategy consists of weed removal from orchards, timely sowing of recommended cotton hybrid, 4 foliar sprays
of 2% potassium nitrate, use of azadirachtin 1500 ppm @5 ml/litre, conservation of natural enemies by avoidance of
insecticides that are harmful (IOBC Class-4) to natural enemies and judicious use of safer pesticides (IOBC class1
and 2). The IPM adoption resulted in the successful management of whitefly and other sucking pests along with a
two to three-fold increase in predator population compared to FP. IPM recorded a substantial reduction in the use of pesticide active ingredients (86%) and the number of sprays (58%) along with high parasitization (35.32β45.98%) of whitefly nymphs by Encarsia sp. IPM provided a significant increase in yield (23%), net return (57.5%) along with
a high benefit cost (B:C) ratio of 2.65
Effect of fungal pretreatment on Solanum nigrum L. leaves biomass aimed at the bioadsorption of heavy metals
832-838Environmental degradation due to water pollution, air pollution and soil pollution has a detrimental effect and create ecological imbalance. These factors are also responsible for the large scale introduction of heavy metal ions into the environment. Conventional treatment methods for the removal of heavy metal ions are not so advantageous as these are highly expensive and also produces toxicant. Keeping this view in the mind, the present study was framed to determine the biosorption of heavy metal ions using Solanum nigrum L. leaf biomass alone and also with Aspergillus oryzae treated S. nigrum leaf biomass. Solanum nigrum L. leaf biomass was used as biosorbent for the biosorption of cobalt, copper, iron,lead and zinc.Unaided S. nigrum leaf biomass was the better absorbant of lead (Pb) whereas when inoculated with A. oryzae cobalt (Co) was more biosorbed than any other heavy metal. Overall, the results of the present study propose that the traditional plant S. nigrum could be used for the bioadsorption of heavy metals
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