393 research outputs found

    Compact Printed CPW-fed UWB antenna with SRR and Quarter wavelength slot with dual band-notched characteristic

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    Volume 2 Issue 3 (March 2014

    ARTYCUL: A Privacy-Preserving ML-Driven Framework to Determine the Popularity of a Cultural Exhibit on Display.

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    We present ARTYCUL (ARTifact popularitY for CULtural heritage), a machine learning(ML)-based framework that graphically represents the footfall around an artifact on display at a museum or a heritage site. The driving factor of this framework was the fact that the presence of security cameras has become universal, including at sites of cultural heritage. ARTYCUL used the video streams of closed-circuit televisions (CCTV) cameras installed in such premises to detect human figures, and their coordinates with respect to the camera frames were used to visualize the density of visitors around the specific display items. Such a framework that can display the popularity of artifacts would aid the curators towards a more optimal organization. Moreover, it could also help to gauge if a certain display item were neglected due to incorrect placement. While items of similar interest can be placed in vicinity of each other, an online recommendation system may also use the reputation of an artifact to catch the eye of the visitors. Artificial intelligence-based solutions are well suited for analysis of internet of things (IoT) traffic due to the inherent veracity and volatile nature of the transmissions. The work done for the development of ARTYCUL provided a deeper insight into the avenues for applications of IoT technology to the cultural heritage domain, and suitability of ML to process real-time data at a fast pace. While we also observed common issues that hinder the utilization of IoT in the cultural domain, the proposed framework was designed keeping in mind the same obstacles and a preference for backward compatibility

    Extrahepatic undifferentiated embryonal sarcoma, cytology as an accurate method for early diagnosis: an extremely rare case report in an Indian child

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    Undifferentiated embryonal sarcoma has been described in the liver, a rare malignant mesenchymal neoplasm, that occurs primarily in children and teenagers. Approximately 260 cases have been reported arising in the liver since 1978 when this disease was first described. Its pathogenesis is still obscure. Authors presented a case of extrahepatic undifferentiated embryonal sarcoma in a 9-year-old female presenting with upper abdominal dull pain. Ultrasound and CT Scan showed normal liver architecture, with liver pushed upwards due to compression by tumor arising in the retroperitoneum. To the best of our knowledge, this is first case of extrahepatic undifferentiated embryonal sarcoma diagnosed on cytomorphology and confirmed by histopathology and immunohistochemistry markers

    Oligomerization of the human immunodeficiency virus type 1 (HIV-1) Vpu protein – a genetic, biochemical and biophysical analysis

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    <p>Abstract</p> <p>Background</p> <p>The human immunodeficiency virus type 1(HIV-1) is a complex retrovirus and the causative agent of acquired immunodeficiency syndrome (AIDS). The HIV-1 Vpu protein is an oligomeric integral membrane protein essential for particle release, viral load and CD4 degradation. <it>In silico </it>models show Vpu to form pentamers with an ion channel activity.</p> <p>Results</p> <p>Using Vpu proteins from a primary subtype C and the pNL4-3 subtype B isolates of HIV-1, we show oligomerization of the full-length protein as well as its transmembrane (TM) domain by genetic, biochemical and biophysical methods. We also provide direct evidence of the presence of Vpu pentamers in a stable equilibrium with its monomers <it>in vitro</it>. This was also true for the TM domain of Vpu. Confocal microscopy localized Vpu to the endoplasmic reticulum and Golgi regions of the cell, as well as to post-Golgi vesicles. In fluorescence resonance energy transfer (FRET) experiments in live cells we show that Vpu oligomerizes in what appears to be either the Golgi region or intracellular vesicles, but not in the ER.</p> <p>Conclusion</p> <p>We provide here direct evidence that the TM domain, is critical for Vpu oligomerization and the most favourable channel assembly is a pentamer. The Vpu oligomerization appears to be either the Golgi region or intracellular vesicles, but not in the ER.</p

    ΠšΠΎΠ½Ρ†Π΅ΠΏΡ†ΠΈΡ Π±Π°Π·ΠΎΠ²ΠΎΠ³ΠΎ Π½Π°Ρ†ΠΈΠΎΠ½Π°Π»ΡŒΠ½ΠΎ-ΠΎΡ€ΠΈΠ΅Π½Ρ‚ΠΈΡ€ΠΎΠ²Π°Π½Π½ΠΎΠ³ΠΎ ΡƒΡ‡Π΅Π±Π½ΠΈΠΊΠ° практичСского курса русского языка для школ Индии

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    In this article conception of modern textbook for students learning Russian out of the language environment is suggested. To achieve this aim it was necessary to solve the following problems: to reveal students' communicative needs, which influence the amount and level of their communicative competence; to give systematic description of the components of structure of the textbook on practical course of Russian language; to analyze the language and communicative components of the manual content and its communicative structure; to elaborate the structure of the manual units, to characterize main teaching technologies realized.Π’ ΡΡ‚Π°Ρ‚ΡŒΠ΅ описываСтся концСпция соврСмСнного школьного ΡƒΡ‡Π΅Π±Π½ΠΈΠΊΠ°, ΠΏΡ€Π΅Π΄Π½Π°Π·Π½Π°Ρ‡Π΅Π½Π½ΠΎΠ³ΠΎ для овладСния русским языком Π²Π½Π΅ языковой срСды. Π‘ этой Ρ†Π΅Π»ΡŒΡŽ ΠΏΠΎΡ‚Ρ€Π΅Π±ΠΎΠ²Π°Π»ΠΎΡΡŒ ΠΏΠΎΡΠ»Π΅Π΄ΠΎΠ²Π°Ρ‚Π΅Π»ΡŒΠ½ΠΎ Ρ€Π΅ΡˆΠ°Ρ‚ΡŒ ΡΠ»Π΅Π΄ΡƒΡŽΡ‰ΠΈΠ΅ Π·Π°Π΄Π°Ρ‡ΠΈ: Π²Ρ‹ΡΠ²ΠΈΡ‚ΡŒ ΠΊΠΎΠΌΠΌΡƒΠ½ΠΈΠΊΠ°Ρ‚ΠΈΠ²Π½Ρ‹Π΅ потрСбности ΠΎΠ±ΡƒΡ‡Π°ΡŽΡ‰ΠΈΡ…ΡΡ, Π²Π»ΠΈΡΡŽΡ‰ΠΈΠ΅ Π½Π° объСм ΠΈ ΡƒΡ€ΠΎΠ²Π΅Π½ΡŒ ΠΈΡ… ΠΊΠΎΠΌΠΌΡƒΠ½ΠΈΠΊΠ°Ρ‚ΠΈΠ²Π½ΠΎΠΉ ΠΊΠΎΠΌΠΏΠ΅Ρ‚Π΅Π½Ρ†ΠΈΠΈ; Π΄Π°Ρ‚ΡŒ цСлостноС систСмноС описаниС структурных ΠΊΠΎΠΌΠΏΠΎΠ½Π΅Π½Ρ‚ΠΎΠ² ΡƒΡ‡Π΅Π±Π½ΠΈΠΊΠ° практичСского курса русского языка ΠΊΠ°ΠΊ иностранного для школьников срСднСй ступСни; ΠΎΠΏΠΈΡΠ°Ρ‚ΡŒ языковыС ΠΈ Ρ€Π΅Ρ‡Π΅Π²Ρ‹Π΅ ΠΊΠΎΠΌΠΏΠΎΠ½Π΅Π½Ρ‚Ρ‹ содСрТания ΡƒΡ‡Π΅Π±Π½ΠΈΠΊΠ°, Π΅Π³ΠΎ ΠΊΠΎΠΌΠΌΡƒΠ½ΠΈΠΊΠ°Ρ‚ΠΈΠ²Π½ΡƒΡŽ ΠΎΡ€Π³Π°Π½ΠΈΠ·Π°Ρ†ΠΈΡŽ; Ρ€Π°ΡΡΠΌΠΎΡ‚Ρ€Π΅Ρ‚ΡŒ вопрос ΠΎ структурС ΡƒΡ€ΠΎΠΊΠΎΠ² ΡƒΡ‡Π΅Π±Π½ΠΈΠΊΠ°; ΠΈΠ·Π»ΠΎΠΆΠΈΡ‚ΡŒ основныС Ρ€Π΅Π°Π»ΠΈΠ·ΡƒΠ΅ΠΌΡ‹Π΅ Π² Π½Π΅ΠΌ Ρ‚Π΅Ρ…Π½ΠΎΠ»ΠΎΠ³ΠΈΠΈ обучСния

    Prospective evaluation of a primary care referral pathway for patients with non-alcoholic fatty liver disease.

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    BACKGROUND & AIMS: We aimed to develop and evaluate a pathway for management of patients with non-alcoholic fatty liver disease (NAFLD) using blood tests to stratify patients in primary care to improve detection of cases of advanced fibrosis and cirrhosis, and avoid unnecessary referrals to secondary care. METHODS: This was a prospective longitudinal cohort study with before-and-after analysis and comparison to unexposed controls. We used a two-step algorithm combining the use of FIB-4 followed by the ELF test if required RESULTS: In total, 3,012 patients were analysed. Use of the pathway detected 5 times more cases of advanced fibrosis (Kleiner F3) and cirrhosis (OR=5.18; 95%CI=2.97 to 9.04; p<0.0001). Unnecessary referrals from primary care to secondary care fell by 81% (OR=0.193; 95%CI 0.111 to 0.337; p<0.0001). Three times more cases of cirrhosis were diagnosed (OR=3.14; 95%CI=1.57 to 24; p=0.00011). Although it was used for only 48% of referrals, significant benefits were observed across all referrals from the practices exposed to the pathway. Unnecessary referrals fell by 77% (OR=0.23; 95% CI=0.658 to 0.082; p=0.006) with a 4-fold improvement in detection of cases of advanced fibrosis and cirrhosis (OR=4.32; 95% CI=1.52 to 12.25; p=0.006). Compared to referrals made before introduction of the pathway, unnecessary referrals fell from 79/83 referrals (95.2%) to 107/152 (70.4%) representing an 88% reduction in unnecessary referrals when the pathway was followed (OR=0.12; 95%CI=0.042 to 0.349; p<0.0001). CONCLUSIONS: The use of non-invasive blood tests for liver fibrosis to stratify patients with NAFLD improves the detection of cases of advanced fibrosis and cirrhosis and reduces unnecessary referrals to secondary care of patients with lesser degrees of liver fibrosis. This strategy improves resource use and benefits patients. LAY SUMMARY: Non-alcoholic fatty liver disease effects up to 30% of the population but only a minority of cases develop liver disease. Our study has shown that established blood tests can be used in primary care to stratify patients with fatty liver disease to reduce unnecessary referrals by 80% and improve the detection of cases of advanced fibrosis 5 fold and cirrhosis 3 fold

    Large-scale IPM validation in whitefly (Bemisia tabaci)-prone cotton (Gossypium spp.) fields adjoining kinnow orchards

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    Whitefly [Bemisia tabaci (Gen)] is a serious sucking pest of cotton in the north zone of India. Cotton (Gossypium spp.) fields adjoining kinnow orchards used to have a quite higher incidence of whiteflies compared to the fields away from orchards. Therefore, the study was carried out at ICAR-National Centre for Integrated Pest Management, New Delhi during 2017–19 to implement integrated pest management (IPM) validation trial in cotton fields located adjoining the kinnow orchards in the village Nihalkhera of district Fazilka, Punjab in farmers’ participatory (FP). The IPM strategy consists of weed removal from orchards, timely sowing of recommended cotton hybrid, 4 foliar sprays of 2% potassium nitrate, use of azadirachtin 1500 ppm @5 ml/litre, conservation of natural enemies by avoidance of insecticides that are harmful (IOBC Class-4) to natural enemies and judicious use of safer pesticides (IOBC class1 and 2). The IPM adoption resulted in the successful management of whitefly and other sucking pests along with a two to three-fold increase in predator population compared to FP. IPM recorded a substantial reduction in the use of pesticide active ingredients (86%) and the number of sprays (58%) along with high parasitization (35.32–45.98%) of whitefly nymphs by Encarsia sp. IPM provided a significant increase in yield (23%), net return (57.5%) along with a high benefit cost (B:C) ratio of 2.65

    Effect of fungal pretreatment on Solanum nigrum L. leaves biomass aimed at the bioadsorption of heavy metals

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    832-838Environmental degradation due to water pollution, air pollution and soil pollution has a detrimental effect and create ecological imbalance. These factors are also responsible for the large scale introduction of heavy metal ions into the environment. Conventional treatment methods for the removal of heavy metal ions are not so advantageous as these are highly expensive and also produces toxicant. Keeping this view in the mind, the present study was framed to determine the biosorption of heavy metal ions using Solanum nigrum L. leaf biomass alone and also with Aspergillus oryzae treated S. nigrum leaf biomass. Solanum nigrum L. leaf biomass was used as biosorbent for the biosorption of cobalt, copper, iron,lead and zinc.Unaided S. nigrum leaf biomass was the better absorbant of lead (Pb) whereas when inoculated with A. oryzae cobalt (Co) was more biosorbed than any other heavy metal. Overall, the results of the present study propose that the traditional plant S. nigrum could be used for the bioadsorption of heavy metals
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