Transient cosmic ray increase associated with a geomagnetic storm

On the basis of worldwide network data of cosmic ray nucleonic components, the transient cosmic ray increase due to the depression of cosmic ray cutoff rigidity during a severe geomagnetic storm was investigated in terms of the longitudinal dependence. Multiple correlation analysis among isotropic and diurnal terms of cosmic ray intensity variations and Dst term of the geomagnetic field is applied to each of various station's data. It is shown that the amplitude of the transient cosmic ray increase associated with Dst depends on the local time of the station, and that its maximum phase is found in the evening sector. This fact is consistent with the theoretical estimation based on the azimuthally asymmetric ring current model for the magnetic DS field

Multigenerational Effects on Children's Cognitive and Socioemotional Outcomes: A Within-Child Investigation

Associations between grandparental investment and child outcomes were investigated using three waves of a longitudinal British Millennium Cohort Study that included children between the ages of 9 months and 5 years (n = 24,614 person-observations from 13,744 children). Grandparental investment was measured by parent–grandparent contact frequency and grandparental financial support. Child cognitive development was measured using the British Ability Scale and socioemotional outcomes using the Strength and Difficulties Questionnaire. Grandparental investment was associated with improved cognitive and socioemotional outcomes among children. However, these associations occurred because of between-person effects and did not exist in within-person analyses that compared the same children over time. The results are discussed in terms of their contribution to multigenerational relationships research.</p

Cancer Incidence and Mortality in the Oldest Old: a Nationwide Study in Finland

The world's population is aging rapidly. This study reports the burden of cancer in the oldest old (≥85 years) in Finland in 1953-2017 and estimates age-specific cancer rates in the old population (65-99 years) in 1988-2017. The Finnish Cancer Registry provided data on all cancer diagnoses, cancer deaths and other deaths in cancer patients in Finland in 1953-2017. Between 1953-1957 and 2013-2017, the proportion of incident cancers in those aged ≥85 years increased from 1.5% to 9.6% (597 to 15,360 new cases), and in 2013-2017, more new cancers were diagnosed at age ≥85 years than age <50 years. Cancer incidence and excess mortality attributable to cancer peaked at age 85-94 years and declined subsequently, whereas cancer-specific mortality continued to increase or plateaued. Due to demographic changes, the number of new cancers in the oldest old has increased substantially in Finland, and currently, nearly one in 10 cancers are diagnosed in this age group. The increasing cancer burden in the oldest old poses a major challenge for healthcare and needs to be addressed in designing clinical research and reporting of cancer registries. In old populations with competing risks of death, we propose excess cancer mortality as a measure of cancer-related mortality.Peer reviewe

The effects of an alpha-2-adrenoceptor agonist, antagonist, and their combination on the blood insulin, glucose, and glucagon concentrations in insulin sensitive and dysregulated horses

Alpha-2-adrenoceptor agonists are sedatives that can cause fluctuations in serum insulin and blood glucose (BG) concentrations in horses. The objectives of this study were to investigate the effects of detomidine and vatinoxan on BG, insulin, and glucagon concentrations in horses with and without insulin dysregulation (ID). In a blinded cross-over design, eight horses with ID and eight horses without ID were assigned to each of four treatments: detomidine (0.02 mg/kg; DET), vatinoxan (0.2 mg/kg; VAT), detomidine + vatinoxan (DET + VAT), and saline control (SAL). Blood samples were taken at 0,1, 2, 4, 6, and 8 h. Change from baseline was used as the response in modelling, and the differences between treatments were evaluated with repeated measures analysis of covariance. P values 2021 The Authors. Published by Elsevier Ltd. This is an open access article under the CC BY license (http://creativecommons.org/licenses/by/4.0/).Peer reviewe

Grandparental Childcare for Biological, Adopted, and Step-Offspring: Findings From Cross-National Surveys

Based on kin selection theory, amounts of grandparental investment should reflect the probability to share common genes with offspring. Adoption may represent a special case, however, yet grandparental investment in adopted children has previously been both theoretically misconstrued and little investigated. Here, we study for the first time how grandparental childcare provision is distributed between biological, adopted, and step-offspring. Using Generations and Gender Surveys (n = 15,168 adult child–grandmother and 12,193 adult child–grandfather dyads) and the Survey of Health, Ageing, and Retirement in Europe (n = 17,233 grandmother–adult child and 13,000 grandfather–adult child dyads), we find that grandparents were less likely to provide care to stepchildren than to adopted and biological children, but no difference between adopted and biological children. These findings were present in both data sets and for both grandmothers and grandfathers, after several potentially confounding factors were taken into account. The stepchild disadvantage is in line with kin selection theory. The congruent amounts of care provided to adopted and biological children may reflect similar levels of adult–child attachment, selection effects, and greater need in adoptive families, as well as some degree of genetical relatedness in the case of kin adoption. The study provides new evidence of biased kin investments in contemporary societies and stresses the importance of psychological motivation and attachment in evolutionary studies of kin investment.</p

Entry into grandparenthood and subjective well-being among older Europeans

The birth of a grandchild is often assumed to increase subjective well-being of older adults. Previous studies, however, have been both scarce and methodologically limited. Here, associations between grandparenthood and subjective well-being (measured by self-rated life satisfaction and meaning of life scores) were investigated using data from the Survey of Health, Aging and Retirement in Europe (SHARE). SHARE is a longitudinal study of individuals aged 50 years and above from 16 countries, including five follow-up waves between 2004 and 2015 (n = 67,110 person-observations from 41,123 persons). Within-person regressions focusing on each participant’s variation in subjective well-being over time were applied to detect changes longitudinally. Becoming a grandparent was associated with increased meaning of life scores among participants. However, similar effects were not found in the case of self-rated life satisfaction. The results are discussed in relation to studies examining whether entering parenthood is associated with subjective well-being.</p