Three-dimensional character of the deformation twin in magnesium

Deformation twins are three-dimensional domains, traditionally viewed as ellipsoids because of their two-dimensional lenticular sections. In this work, we performed statistical analysis of twin shapes viewing along three orthogonal directions: the ‘dark side’ (DS) view along the twin shear direction (η1), the twinning plane normal (TPN) view (k1) and the ‘bright side’ (BS) view along the direction λ(=k1 × η1). Our electron back-scatter diffraction results show that twins in the DS and BS views normally exhibit a lenticular shape, whereas they show an irregular shape in the TPN view. Moreover, the findings in the TPN view revealed that twins grow faster along λ the lateral direction than along η1 the forward propagation direction at the initial stages of twin growth. These twin sections are irregular, indicating that growth is locally controlled and the overall shape is not perfectly ellipsoidal. We explain these findings using atomistic models, and ascribe them to differences in the mobility of the edge and screw components of the twinning dislocations

Three-dimensional character of the deformation twin in magnesium

Deformation twins are three-dimensional domains, traditionally viewed as ellipsoids because of their two-dimensional lenticular sections. In this work, we performed statistical analysis of twin shapes viewing along three orthogonal directions: the ‘dark side’ (DS) view along the twin shear direction (η1), the twinning plane normal (TPN) view (k1) and the ‘bright side’ (BS) view along the direction λ(=k1 × η1). Our electron back-scatter diffraction results show that twins in the DS and BS views normally exhibit a lenticular shape, whereas they show an irregular shape in the TPN view. Moreover, the findings in the TPN view revealed that twins grow faster along λ the lateral direction than along η1 the forward propagation direction at the initial stages of twin growth. These twin sections are irregular, indicating that growth is locally controlled and the overall shape is not perfectly ellipsoidal. We explain these findings using atomistic models, and ascribe them to differences in the mobility of the edge and screw components of the twinning dislocations

Inactivated Pseudomonas aeruginosa inhibits hypoxia-induced pulmonary hypertension by preventing TGF-β1/Smad signaling

Pseudomonas aeruginosa is one of the common colonizing bacteria of the human body and is an opportunistic pathogen frequently associated with respiratory infections. Inactivated P. aeruginosa (IPA) have a variety of biological effects against inflammation and allergy. Transforming growth factor-β (TGF-β) signaling plays a critical role in the regulation of cell growth, differentiation, and development in a wide range of biological systems. The present study was designed to investigate the effects of IPA on TGF-β/Smad signaling in vivo, using a hypoxia-induced pulmonary hypertension (PH) rat model. Sprague Dawley rats (n=40) were exposed to 10% oxygen for 21 days to induce PH. At the same time, IPA was administered intravenously from day 1 to day 14. Mean pulmonary artery pressure (mPAP) and the right ventricle (RV) to left ventricle plus the interventricular septum (LV+S) mass ratio were used to evaluate the development of PH. Vessel thickness and density were measured using immunohistochemistry. Primary arterial smooth muscle cells (PASMCs) were isolated and the proliferation of PASMCs was assayed by flow cytometry. The production of TGF-β1 in cultured supernatant of PASMCs was assayed by ELISA. The expression levels of α-smooth muscle actin (α-SMA), TGF-β1 and phospho-Smad 2/3 in PASMCs were assayed by western blot. Our data indicated that IPA attenuated PH, RV hypertrophy and pulmonary vascular remodeling in rats, which was probably mediated by restraining the hypoxia-induced overactive TGF-β1/Smad signaling. In conclusion, IPA is a promising protective treatment in PH due to the inhibiting effects on TGF-β1/Smad 2/3 signaling

A new construction of signature waveforms for multi-rate multi-cell QS-CDMA systems

The full published version of this paper can be accessed at the link below. Copyright © 2008, Springer Science+Business Media, LLC. Permission to reprint/republish this material must be obtained from the publisher.In this paper, we propose a newconstruction of signaturewaveform sets based on Generalized Loosely Synchronization (GLS) sets and different chipwaveforms. The newsignature sets are applied into the multi-rate multi-cell quasi-synchronous CDMA (QS-CDMA) system where each cell is assigned with aGLS set; different users in the same cell are assigned with different GLS sequences in the same GLS set; user’s different streams are assigned with the same GLS sequence but different chip waveforms. According to the properties of GLS sets, the inter-cell interference (ICI) and the multi-user interference (MUI) in the same cell can be reduced significantly. The interferences among different streams of the same user are handled by an optimal (or suboptimal) multi-stream detector(s), notice that the multi-stream detector mentioned here is also named as multi-user detector in other references. We compare the performance of the multi-rate multi-cell QS-CDMA system employing the proposed sets with that of multi-rate system employing well-known concatenated orthogonal/PN sets and that of single-rate system employing GLS sets. The results show that the multi-rate system employing the proposed sets can achieve significant interference reduction. Meanwhile the performance of multi-rate system is similar to that of single-rate system due to the inclusion of multi-user detection.This work was supported by the National Science Foundation of China (NSFC) under the Grant No.60772087/90604035, the National 863 High-Tech R&D Program under the Grant No. 2007AA01 Z228, the 111 Project under the Grant No. 111-2-1

Numerical Simulation of Wave-Structure Interaction around an Obstacle

Sixth Conference on Design and Modeling of Mechanical Systems (CMSM 2015), Hammamet, TUNISIA, MAR 23-25, 2015International audienceIn this work, we study a turbulent two-phase free surface flow around an obstacle in unsteady regime. A dynamic study relating to the formation of coherent vortex structures enables us to determine the shape of the flow and to clarify its main characteristics (shear layer, recirculation and reattachment). We determine first the dynamic structure of the flow through a numerical approach using the computer code ANSYS Fluent (closure model is k-epsilon). In the second part we study the impact of these vortices on such configurations. A series of numerical simulations have been conducted to further verify the applicability of this model for wave simulations interaction with vortex structures of various shapes