2,375 research outputs found
Andreev Reflection and Spin Injection into and wave Superconductors
We study the effect of spin injection into and wave superconductors,
with an emphasis on the interplay between boundary and bulk spin transport
properties. The quantities of interest include the amount of non-equilibrium
magnetization (), as well as the induced spin-dependent current () and
boundary voltage (). In general, the Andreev reflection makes each of the
three quantities depend on a different combination of the boundary and bulk
contributions. The situation simplifies either for half-metallic ferromagnets
or in the strong barrier limit, where both and depend solely on the
bulk spin transport/relaxation properties. The implications of our results for
the on-going spin injection experiments in high cuprates are discussed.Comment: 4 pages, REVTEX, 1 figure included; typos correcte
Spin current in ferromagnet/insulator/superconductor junctions
A theory of spin polarized tunneling spectroscopy based on a scattering
theory is given for tunneling junctions between ferromagnets and d-wave
superconductors. The spin filtering effect of an exchange field in the
insulator is also treated. We clarify that the properties of the Andreev
reflection are largely modified due to a presence of an exchange field in the
ferromagnets, and consequently the Andreev reflected quasiparticle shows an
evanescent-wave behavior depending on the injection angle of the quasiparticle.
Conductance formulas for the spin current as well as the charge current are
given as a function of the applied voltage and the spin-polarization in the
ferromagnet for arbitrary barrier heights. It is shown that the surface bound
states do not contribute to the spin current and that the zero-bias conductance
peak expected for a d-wave superconductor splits into two peaks under the
influence of the exchange interaction in the insulator.Comment: 14 pages, 11 figure
Gut microbial metabolites of linoleic acid are metabolized by accelerated peroxisomal β-oxidation in mammalian cells
Microorganisms in animal gut produce unusual fatty acids from the ingested diet. Two types of hydroxy fatty acids (HFAs), 10-hydroxy-cis-12-octadecenoic acid (HYA) and 10-hydroxy-octadecanoic acid (HYB), are linoleic acid (LA) metabolites produced by Lactobacillus plantarum. In this study, we investigated the metabolism of these HFAs in mammalian cells. When Chinese hamster ovary (CHO) cells were cultured with HYA, approximately 50% of the supplemented HYA disappeared from the dish within 24 hours. On the other hand, the amount of HYA that disappeared from the dish of peroxisome (PEX)-deficient CHO cells was lower than 20%. Significant amounts of C2- and C4-chain-shortened metabolites of HYA were detected in culture medium of HYA-supplemented CHO cells, but not in medium of PEX-deficient cells. These results suggested that peroxisomal β-oxidation is involved in the disappearance of HYA. The PEX-dependent disappearance was observed in the experiment with HYB, but not with LA. We also found that HYA treatment up-regulates peroxisomal β-oxidation activity of human gastric MKN74 cells and intestinal Caco-2 cells. These results indicate a possibility that HFAs produced from gut bacteria affect lipid metabolism of host via modulation of peroxisomal β-oxidation activity
Electromagnetic wave diffraction by periodic planar metamaterials with nonlinear constituents
We present a theory which explains how to achieve an enhancement of nonlinear
effects in a thin layer of nonlinear medium by involving a planar periodic
structure specially designed to bear a trapped-mode resonant regime. In
particular, the possibility of a nonlinear thin metamaterial to produce the
bistable response at a relatively low input intensity due to a large quality
factor of the trapped-mode resonance is shown. Also a simple design of an
all-dielectric low-loss silicon-based planar metamaterial which can provide an
extremely sharp resonant reflection and transmission is proposed. The designed
metamaterial is envisioned for aggregating with a pumped active medium to
achieve an enhancement of quantum dots luminescence and to produce an
all-dielectric analog of a 'lasing spaser'.Comment: 18 pages, 13 figure
Functional Amyloid Formation within Mammalian Tissue
Amyloid is a generally insoluble, fibrous cross-β sheet protein aggregate. The process of amyloidogenesis is associated with a variety of neurodegenerative diseases including Alzheimer, Parkinson, and Huntington disease. We report the discovery of an unprecedented functional mammalian amyloid structure generated by the protein Pmel17. This discovery demonstrates that amyloid is a fundamental nonpathological protein fold utilized by organisms from bacteria to humans. We have found that Pmel17 amyloid templates and accelerates the covalent polymerization of reactive small molecules into melanin—a critically important biopolymer that protects against a broad range of cytotoxic insults including UV and oxidative damage. Pmel17 amyloid also appears to play a role in mitigating the toxicity associated with melanin formation by sequestering and minimizing diffusion of highly reactive, toxic melanin precursors out of the melanosome. Intracellular Pmel17 amyloidogenesis is carefully orchestrated by the secretory pathway, utilizing membrane sequestration and proteolytic steps to protect the cell from amyloid and amyloidogenic intermediates that can be toxic. While functional and pathological amyloid share similar structural features, critical differences in packaging and kinetics of assembly enable the usage of Pmel17 amyloid for normal function. The discovery of native Pmel17 amyloid in mammals provides key insight into the molecular basis of both melanin formation and amyloid pathology, and demonstrates that native amyloid (amyloidin) may be an ancient, evolutionarily conserved protein quaternary structure underpinning diverse pathways contributing to normal cell and tissue physiology
Characterisation of an Escherichia coli line that completely lacks ribonucleotide reduction yields insights into the evolution of parasitism and endosymbiosis
Life requires ribonucleotide reduction for de novo synthesis of deoxyribonucleotides. As ribonucleotide reduction has on occasion been lost in parasites and endosymbionts, which are instead dependent on their host for deoxyribonucleotide synthesis, it should in principle be possible to knock this process out if growth media are supplemented with deoxyribonucleosides. We report the creation of a strain of Escherichia coli where all three ribonucleotide reductase operons have been deleted following introduction of a broad spectrum deoxyribonucleoside kinase from Mycoplasma mycoides. Our strain shows slowed but substantial growth in the presence of deoxyribonucleosides. Under limiting deoxyribonucleoside levels, we observe a distinctive filamentous cell morphology, where cells grow but do not appear to divide regularly. Finally, we examined whether our lines can adapt to limited supplies of deoxyribonucleosides, as might occur in the switch from de novo synthesis to dependence on host production during the evolution of parasitism or endosymbiosis. Over the course of an evolution experiment, we observe a 25-fold reduction in the minimum concentration of exogenous deoxyribonucleosides necessary for growth. Genome analysis reveals that several replicate lines carry mutations in deoB and cdd. deoB codes for phosphopentomutase, a key part of the deoxyriboaldolase pathway, which has been hypothesised as an alternative to ribonucleotide reduction for deoxyribonucleotide synthesis. Rather than complementing the loss of ribonucleotide reduction, our experiments reveal that mutations appear that reduce or eliminate the capacity for this pathway to catabolise deoxyribonucleotides, thus preventing their loss via central metabolism. Mutational inactivation of both deoB and cdd is also observed in a number of obligate intracellular bacteria that have lost ribonucleotide reduction. We conclude that our experiments recapitulate key evolutionary steps in the adaptation to life without ribonucleotide reduction
Hydrogen peroxide bleaching of cellulose pulps obtained from brewer’s spent grain
Brewer’s spent grain (BSG) was evaluated
for bleached pulp production. Two cellulose pulps with
different chemical compositionswere produced by soda
pulping: one from the original raw material and the
other from material pretreated by dilute acid. Both of
them were bleached by a totally chlorine-free sequence
performed in three stages, using 5% hydrogen peroxide
in the two initial, and a 0.25 NNaOHsolution in the last one. Chemical composition, kappa number, viscosity, brightness and yield of bleached and unbleached pulps were evaluated. The high hemicellulose (28.4% w/w) and extractives (5.8% w/w) contents in original BSG affected the pulping and bleaching processes.However, soda pulping of acid pretreated BSG gave a celluloserich pulp (90.4% w/w) with low hemicellulose and
extractives contents (7.9% w/w and <3.4% w/w, respectively), which was easily bleached achieving a kappa number of 11.21, viscosity of 3.12 cp, brightness of 71.3%, cellulose content of 95.7% w/w, and residual lignin of 3.4% w/w. Alkaline and oxidative delignification of acid pretreated BSG was found as an attractive approach for producing high-purity, chlorine-free cellulose pulp.FAPESP (Fundação de Amparo
à Pesquisa do Estado de São Paulo), Brazil.CNPq (Conselho Nacional de Desenvolvimento
Científico e Tecnológico).Capes
(Coordenação de Aperfeiçoamento de Pessoal de Nível
Superior)
Superconductivity of FeSe0.5Te0.5 Thin Films Grown by Pulsed Laser Deposition
FeSe0.5Te0.5 thin films with PbO-type structure are successfully grown on
MgO(100) and LaSrAlO4(001) substrates from FeSe0.5Te0.5 or FeSe0.5Te0.75
polycrystalline targets by pulsed-laser deposition. The film deposited on the
MgO substrate (film thickness ~ 55 nm) shows superconductivity at 10.6 K
(onset) and 9.2 K (zero resistivity). On the other hand, the film deposited on
the LaSrAlO4 substrate (film thickness ~ 250 nm) exhibits superconductivity at
5.4 K (onset) and 2.7 K (zero resistivity). This suggests the strong influence
of substrate materials and/or the c-axis length to superconducting properties
of FeSe0.5Te0.5 thin films.Comment: 24 pages, 5 figure
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