Effect Of Aspect Ratio On Torsional Capacity Of High-Strength Plain Concrete Deep Beams

Twenty high-strength plain concrete deep beams were tested under torsion. The variables were concrete strength and depth/width (aspect) ratio. Concrete strengths of 51.01, 58.53, 76.60 and 83.66 MPa and depth/width (aspect) ratios varying from 1 to 5 were used. The tested beams failed suddenly and violently along a smooth surface. The crack inclinations on the beam surfaces were influenced by the concrete strength and aspect ratio. Test results show that by increasing the concrete strength or by reducing the aspect ratio, the torsional capacity and the beam stiffness increases while the angle of twist decreases. A modification has been suggested to the strength equation of the ACI Code 318-89 for normal-strength concrete shallow beams under torsion to include the effect of high-strength concrete for deep beams. The proposed equation gave .a. good estimate of the experimental torsional strength

Urgensi Pelatihan Fiqih Darah Wanita Untuk Masyarakat Lowokwaru

Pembahasan soal darah pada wanita yaitu haid, nifas, dan istihadhah adalah pembahasan yang paling sering dipertanyakan oleh kaum wanita. Dan pembahasan ini juga merupakan salah satu bahasan yang tersulit dalam masalah fiqih, sehingga banyak yang keliru  dalam memahaminya. Bahkan meski pembahasannya telah berulang-ulang kali disampaikan, masih banyak wanita Muslimah yang belum memahami kaidah dan perbedaan dari ketiga darah ini. Mungkin ini dikarenakan darah tersebut keluar dari jalur yang sama namun pada setiap wanita tentulah keadaannya tidak selalu sama, dan berbeda pula hukum dan penanganannya. Untuk memahamkan wanita Muslimah di Dinoyo Lowokwaru, Tim Dosen UIN mengabdi menjalin kerjasama dengan khodim Pondok Pesantren Al Wafa Dinoyo. Tim ini melakukan pengabdian dengan tujuan (1) Untuk mengetahui pengetahuan masyarakat Muslimah Dinoyo Lowokwaru dalam memahami fiqih darah wanita, (2) Untuk mengetahui upaya apa saja yang ditempuh masyarakat Muslimah Dinoyo Lowokwaru dalam memahami fiqih darah wanita Tim Dosen ini menggunakan metode Participatory Action Research (PAR). PAR disini adalah proses dengan mana komunitas-komunitas berusaha mempelajari masalah secara ilmiah dalam rangka memandu, memperbaiki, dan mengevaluasi keputusan dan aksi mereka. Cara-cara penelitian yang selama ini biasa dilakukan kalangan akademisi dan peneliti dalam komunitas kita, justru dapat menjadi tantangan dan ancaman bagi sebuah komunitas. Hubungan antara penelitian ilmiah (intellectual research) dapat menjadi intrusive dan exclusive. Hasil dari pengabdian ini adalah (1) Muslimah dinoyo Para muslimah  paham betul tentang jenis-jenis darah yang keluar dari wanita, (2) Para muslimah  paham betul tentang konsenkuensi fiqih dari jenis-jenis darah yang keluar dari wanit

Suspension of Justice Isa Ayo Salami: Implications for Rule of Law, Judicial Independence and Constitutionalism

The suspension of Justice Ayo Salami, President of the Court of Appeal (PCA) opened a new dimension in the Nigerian judiciary; it is the first of its kind at that level. The National Judicial Council (NJC) initiated the suspension and the President of the Federal Republic of Nigeria endorsed it. The paper is concerned with implications of the suspension for the rule of law, constitutionalism and judicial independence. The paper argues that the suspension was unconstitutional for procedural irregularity and further reveals that the mechanisms provided by the constitution to guarantee judicial independence are inadequate and ineffective. It also shows that the much-needed independence of judiciary from the political branches in particular, to a greater extent, depends on internal independence which again largely depends on the leadership of the judiciary and the National Judicial Council. This invariably suggests that for there to be independence from the political branches and internal interference there must be a courageous, just, fearless and pro-active leadership of the judiciary and a more independent Judicial Council, and calls for an amendment to the constitution in that direction

The effect of social support around pregnancy on postpartum depression among Canadian teen mothers and adult mothers in the maternity experiences survey

BACKGROUND: Postpartum depression (PPD) is a mood disorder that affects 10–20 percent of women, and can begin any time during first year after delivery lasting for months. Social support may decrease risk of depression during pregnancy for women. However, literature shows that the amount of social support received during and after pregnancy is different for teen mothers and adult mothers. This study examined the effects of social support received during and after pregnancy on PPD among Canadian women and identified if the relationship was different for teen mothers compared to adult mothers. METHODS: The study was based on secondary analysis of the Maternity Experiences Survey. A total of 6,421 women with singleton live births, aged 15 years and older were analyzed. Teen mothers were identified as 15–19 years old and adult mothers were identified as 20 years and older. The main outcome of the study was PPD, which was evaluated using the Edinburg Postnatal Depression Scale. The main independent variable was social support received during pregnancy and after birth. Logistic regression was computed to assess the relationship between social support and PPD after adjusting for confounding variables and age as an interaction term. Adjusted Odds Ratios and 95% Confidence Intervals were reported. RESULTS: PPD was experienced by 14.0% among teen mothers and 7.2% among adult mothers (p < .001). Overall, teen mothers reported receiving more support during pregnancy and after birth than adult mothers (p < .010). The relationship between social support and PPD did not significantly differ for teen compared to adult mothers. Both teen and adult mothers were approximately five times more likely to experience PPD if they received no support or minimal support after the birth of the baby (95% CI, 3.51-7.36). CONCLUSION: Receiving social support especially after birth is important for mothers of all ages to reduce the risk of PPD

Effect of consanguinity on birth weight for gestational age in a developing country.

Consanguinity, the marriage between relatives, has been associated with adverse child health outcomes because it increases homozygosity of recessive alleles. The objective of this study was to assess the effect of consanguinity on the birth weight of newborns in Greater Beirut, Lebanon. Cross-sectional data were collected on 10,289 consecutive liveborn singleton newborns admitted to eight hospitals belonging to the National Collaborative Perinatal Neonatal Network during the years 2000 and 2001. Birth weight was modeled by use of the fetal growth ratio, defined as the ratio of the observed birth weight to the median birth weight for gestational age. A mixed-effect multiple linear regression model was used to predict the net effect of first- and second-cousin marriage on the birth weight for gestational age, accounting for within-hospital clustering of data. After controlling for medical and sociodemographic covariates, the authors found a statistically significant negative association between consanguinity and birth weight at each gestational age. No significant difference was observed in the decrease in birth weight between the first- and second-cousin marriages. Overall, consanguinity was associated with a decrease in birth weight for gestational age by 1.8% (beta = -0.018, 95% confidence interval: -0.027, -0.008). The largest effects on fetal growth were seen with lower parity and smoking during pregnancy

Targeted polypharmacology: discovery of dual inhibitors of tyrosine and phosphoinositide kinases.

The clinical success of multitargeted kinase inhibitors has stimulated efforts to identify promiscuous drugs with optimal selectivity profiles. It remains unclear to what extent such drugs can be rationally designed, particularly for combinations of targets that are structurally divergent. Here we report the systematic discovery of molecules that potently inhibit both tyrosine kinases and phosphatidylinositol-3-OH kinases, two protein families that are among the most intensely pursued cancer drug targets. Through iterative chemical synthesis, X-ray crystallography and kinome-level biochemical profiling, we identified compounds that inhibit a spectrum of new target combinations in these two families. Crystal structures revealed that the dual selectivity of these molecules is controlled by a hydrophobic pocket conserved in both enzyme classes and accessible through a rotatable bond in the drug skeleton. We show that one compound, PP121, blocks the proliferation of tumor cells by direct inhibition of oncogenic tyrosine kinases and phosphatidylinositol-3-OH kinases. These molecules demonstrate the feasibility of accessing a chemical space that intersects two families of oncogenes

Knowledge Regarding Secondary Prevention Lifestyle Practices Among Patients with Ischaemic Heart Disease in Oman : Pilot study

Objectives: Secondary prevention of ischaemic heart disease (IHD) is very important. This study aimed to assess knowledge of necessary lifestyle changes among Omani patients diagnosed with IHD. Methods: This cross-sectional pilot study took place between October 2015 and February 2016 at the Sultan Qaboos University Hospital (SQUH), Muscat, Oman. A total of 30 random patients with IHD from the Cardiology Outpatient Clinic of SQUH were included. A 30-item survey was used to determine patients’ knowledge of necessary lifestyle practices following their IHD diagnosis, with scores of &lt;70% indicating poor knowledge. Results: Overall, 21 patients (70.0%) had low knowledge levels. Scores ranged from 38.9−94.4% (mean: 60.7% ± 14.1%). No demographic factors were found to predict low scores, although there were some differences in individual questions. Conclusion: Low knowledge levels regarding lifestyle changes were observed among IHD patients in Oman. More efforts should be made to educate these patients for the secondary prevention of IHD