3 research outputs found
Electrochemical operational principles and analytical performance of Pd-based amperometric nanobiosensors
Palladium nanoparticles (Pd-NPs) have been approved as an effective catalyst for hydrogen peroxide
decomposition which is released during specific enzymatic reactions. However, the general operational
principles and electrochemical performance of Pd-NPs-based nanobiosensors have been poorly
exploited. Here, the electrochemical behavior of oxidase-associated peroxide oxidation co-catalysis of
the modelled microanalytical system based on screen-printed electrodes modified by electroplated PdNPs as an electrocatalyst, glucose oxidase (GOx) or alcohol oxidase (AOx) as a bioreceptor and the
ionomer Nafion as a polymeric binding agent was studied in detail. The impact of palladium surface
oxides and adsorbed oxygen on the activity and product selectivity in an oxidase type of nanobiosensor
was ascertained. To avoid PdO and oxygen electroreduction affecting the entire amperometric response
of Pd-NPs-based nanobiosensors, a special two-step polarization procedure was proposed. Under the
established electrochemical conditions, Pd-NPs-based nanobiosensors with encapsulated oxidases
showed a wide dynamic range towards selective bioanalyte detection, excellent basic line stability, accuracy and resistance to the presence of interfering electrochemical species. This work can serve as a
guideline for the search and validation of operational principles of novel biosensors based on
nanoparticles
Palladium Nanoparticles–Polypyrrole Composite as Effective Catalyst for Fluoroalkylation of Alkenes
© 2018, Springer Science+Business Media, LLC, part of Springer Nature. Abstract: Palladium nanoparticles–polypyrrole composite (Pd/PPy) catalyzes the addition of perfluoroalkyl halides to olefins to produce a variety of products with good yields. An effective fluoroalkylation technique tested with various olefins, fluoroalkyl halides and Pd/PPy was developed. The reaction proceeds highly efficient under mild phosphine-free reaction conditions with different substrates, easy catalyst recycling and provides a general and straightforward access to fluoroalkylated products. Furthermore, we were able to control whether the addition of perfluoroalkyl occurs with various monomer (fluoroalkylated alkene or alkane with RF and OH moieties) or dimer formation (under electrochemical conditions). Graphical Abstract: [Figure not available: see fulltext.]
Palladium Nanoparticles–Polypyrrole Composite as Effective Catalyst for Fluoroalkylation of Alkenes
© 2018, Springer Science+Business Media, LLC, part of Springer Nature. Abstract: Palladium nanoparticles–polypyrrole composite (Pd/PPy) catalyzes the addition of perfluoroalkyl halides to olefins to produce a variety of products with good yields. An effective fluoroalkylation technique tested with various olefins, fluoroalkyl halides and Pd/PPy was developed. The reaction proceeds highly efficient under mild phosphine-free reaction conditions with different substrates, easy catalyst recycling and provides a general and straightforward access to fluoroalkylated products. Furthermore, we were able to control whether the addition of perfluoroalkyl occurs with various monomer (fluoroalkylated alkene or alkane with RF and OH moieties) or dimer formation (under electrochemical conditions). Graphical Abstract: [Figure not available: see fulltext.]