43 research outputs found

    Roles of values in the risk factors of passive suicide ideation among young adults in the US and Japan

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    The present study examined how the importance of values and perceived value congruence with families, friends, and country would be associated with the risk factors of passive suicide ideation. Specifically, the study investigated the associations that the values and perceived congruence had with thwarted belongingness and perceived burdensomeness during the COVID-19 pandemic after controlling for the impact of depression levels. The data from the US and Japan demonstrated that the values such as cherishing family and friends and value congruence played a protective factor for Japanese participants; however, the associations differed among those in the US. Values such as enduring challenges played a protective factor for perceived burdensomeness in Japan whereas values such as cherishing family and friends played a protective factor and improving society was a risk factor for thwarted belongingness for those in the US. These results can be used to further understand the roles of values in mental health

    カンケイ ドウブツ アオゴカイ Perinereis aibuhitensis キョダイ ヘモグロビン ノ グロビンサ ニ フクマレル ケウナ SSケツゴウ

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    The extracellular hemoglobin (Hb) from the polychaete Perinereis aibuhitensis consists of four types of 144 globins and two types of 36 linker chains,having a molecular mass of about 3,500 kDa. There are two types of globin subunits: monomer chain a and disulfide-bondedt rimer AbB. The amino acid sequences of the four globin chains (a,A ,b ,B ) were already reported,previously (Yamanaka,M. et al. Natural Science Research of Tokushima University, 19, 63-92, 2005). The site of disulfide bonds in the globin subunits have been investigated. Each globin chain contains an intrachain disulfide bond between N-terminal and C-terminal Cys residues. In addition,the interchain disulfide bonds were found between chains A and b,and b and B. Therefore,it is elucidated that the chain b is situated at the center of disulfide-bonded trimer,such as A-b-B.The sites of disulfide-bonds determined all could be suitably fitted to the tree dimensional structure of each subunit in a model without stretching or twisting. It was also confirmed that there is no free Cys residue in Peinereis globins. The positions of Cys residues of Perinereis globin sequences were compared wIth those of other 27 chains derived from the homologous Hbs. Among 31 sequences,Cys residues were distributed in six sites. The sites 1 and 2 are located at the N-terminal region of amino acid sequences,the sItes 3 and 4 at the central region,and the sites 5 and 6 at C-terminal region. Furthermore,the Cys distribution was categorized into eight patterns. Perinereis Hb has four patterns I,IV,VII,VIII,be ing lack of the central sites 3 and 4. It should be noted that the pattern II includes the unique globins from Hbs of Lamellibrachia,Riftia and Oligobrachia that carry H2S to the symbiotic bacteria,suggesting that these globin chains might carry H2S in vivo. The phylogenetic tree of 31 globin chains derived from the giant Hbs is divided into two families A and B, as already poited out by us Previously. The family A indudes pattern I-V,whereas the family B includes V- VIII

    Reassociation of annelid giant hemoglobin from the polychaete Perinereis aibuhitensis

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    Annelid extracellular hemoglobin (Hb) is a supramolecule with molecular mass of ~3,500kDa. The giant Hb consists of 12 subassemblies (globin dodecamers, D) and 18 homodimeric linkers (L) of non-globin chain. The globin dodecamer and linker were isolated from the polychaete Perinereis aibuhittensis Hb separately. Subsequently, these two components were mixed in the presence of 1M urea at a neutral pH to reform a whole molecule of Hb. At first L was refined by reverse phase chromatography in organic solvent. On the other hand, Perinereis Hb was incubated in 4M urea solution at 4°C for 5 min, and applied to two amphoteric ion-exchange resin column to remove L stick to the resin, and to isolate only D. The eluate was condensed and subjected to gel filtration. As a result, an ingredient of molecule mass ~210 kDa, that is D, was provided in high yield. When D and L were mixed in the molar ratio of approximately 1:1 in 50mM phosphate buffer (pH 7.2) in the presence of 1 M urea at room temperature, most of the proteins met to natural Hb size again within about 20 hours. Furthermore, similar experiments were performed in 50 mM Tris-HCl buffer (pH 7.2) containing 1 M urea in the presence of 1 mM CaCl2 or 1mM EDTA. It was observed that the reassociation was affected substantially by the presence of Ca2+. In conclusion, the homodimeric linkers have the key role to form the gigantic Hb

    聖隷クリストファー大学看護基礎教育における2020年度シミュレーション教育の実践報告

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    紀要委員会企画Special Articles 本報告では、聖隷クリストファー大学看護基礎教育における2020 年度のシミュレーション教育委員会の活動報告および各領域における実践について、以下の内容をふまえ報告する。 ①シミュレーション教育の実践環境の構築および学内研修、②コロナ禍における通信設備・運用のテクニカルサポート、③シミュレーション教育の実践(看護学部各領域におけるシミュレーション教育の実践内容)、④看護学部シミュレーション教育ホームページ、⑤本学看護学部のシミュレーション教育に関する国内外の学会発表の実績 今後もシミュレーション教育を推進するための本学の課題である、教育環境のさらなる充実、人員の確保、地域の拠点としてのシミュレーション教育の推進、活動のための運営資金の獲得を目指すべく、近隣施設との連携、研究推進とともに、教員の理解と同意を得ながらさらなる教育環境の整備や教育力の向上のため邁進していく

    TRIPD - Trauma, Resilience, Interpersonal Sensitivity, PTG, and Depression Stigma

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    This project was designed to understand the differences between PTG and resiliency by looking at their respective relationships with interpersonal sensitivity and depression stigm

    Younger people, and stronger effects of all-or-nothing thoughts on aggression: Moderating effects of age on the relationships between dichotomous thinking and aggression

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    Binary or dichotomous thinking may lead to aggression throughout people’s lifespan; additionally, relationships are likely to be affected by types of aggression (i.e. physical aggression, verbal aggression, anger, and hostility) as well as gender and age. Using large-scale data (N = 2,315), the current study tested if age or gender moderated dichotomous thinking’s correlation with four different types of aggression. Participants (Mage = 36.1, SD = 16.2, range = 18–69) completed the Dichotomous Thinking Inventory and the Buss-Perry Aggression Questionnaire. Dichotomous thinking differentially affected aggression depending on participants’ age: dichotomous thinking and aggression were more strongly correlated in younger participants. Individuals’ tendency to think dichotomously appeared relatively stable; however, age appeared to moderate dichotomous thinking’s effects

    Humor Styles, Positive Personality and Health

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    The research examines the relationship of sense of humor differences and positive personality qualities with perceptions of stress and well-being. Positive and negative styles of self-directed humor were assumed to have opposing relationships with perceived stress, but the relationships were predicted to be mediated through positive personality qualities. University students provided data at two points in time separated by 8 weeks. Data from time 1 was used to verify the mediation of the relationship of sense of humor with perceived stress through the positive personality qualities. A more extensive theoretical model, using longitudinal data, was tested using the sense of humor measures from time 1 and positive personality qualities at time 2 to predict perceived stress and well-being at time 2. The results from the two analyses support the proposed mediator model in which the potential health benefits of a positive humor style and the potential damage to health associated with a negative humor style are mediated through the positive personality qualities. Thus, it would appear that good humor uses can support maintaining a stable positive personality style, which has positive associations with both psychological and physical well-being
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