152 research outputs found
A migráció bűnügyi hatásai
Additional file 1. Example of waveform recordings and Fourier amplitude spectra
Repetitive Synthetic Method for <i>o</i>,<i>o</i>,<i>p</i>‑Oligophenylenes Using C–H Arylation
A synthetic method for the preparation of <i>o</i>,<i>o</i>,<i>p</i>-oligophenylenes has been developed. It involves Miura’s C–H arylation of 2-biphenols with aryl nonaflates as the key step. Oligophenylenes with defined lengths are successfully synthesized using this method
Annual event rate on each randomized regimen.
<p>Annual event rate on each randomized regimen.</p
Forest plot with OR of prolonged-DAPT relative to short-DAPT for each clinical outcome for the DAPT trial and the pooled population excluding the DAPT trial.
<p>ORs are shown on a logarithmic scale. CI = confidence interval, DAPT = dual anti-platelet therapy, and OR = odds ratio.</p
Estimated annual event rates for myocardial infarction and stent thrombosis in the short-DAPT group during aspirin mono-therapy.
<p>The landmark data was not available for myocardial infarction in the RESET and EXCELLENT trials. NA = not available.</p
MOESM1 of Systematic difference between first-motion and waveform-inversion solutions for shallow offshore earthquakes due to a low-angle dipping slab
Additional file 1: Figure S1. First-motion solutions of aftershocks of the 2016 Off Mie earthquake. Focal spheres with magnitudes of 2.5–3.4 were plotted referring the Hi-net catalog (last accessed 19 April 2016). Location of the epicenter of the 2016 Off Mie earthquake is given by the yellow star. Figure S2. Same as Fig. 1b but for four additional earthquakes (Events A, B, D and E of Table S1). Figure S3. 1D velocity structure model by Ukawa et al. [1984]. Red and green lines are depth variations of P- and S-wave velocities, respectively. Figure S4. Theoretical travel using 1D velocity structure model by Ukawa et al. [1984]. Table S1. Parameters of earthquake used in this study. ϕ S , δ and λ are strike, dip, and rake angles of focal mechanism, respectively. Table S2. Physical parameters for each layer. P- and S-wave velocities (V P , V S ), densities (ρ), and anelastic attenuation (Q P , Q S ) of the JIVSM [Koketsu et al. 2012]
4,5-Dicyano-3,6-diethylbenzo-1,2-diselenete, a Highly Stable 1,2-Diselenete: Its Preparation, Structural Characterization, Calculated Molecular Orbitals, and Complexation with Tetrakis(triphenylphosphine)palladium
The
first isolable benzo-1,2-diselenete, 4,5-dicyano-3,6-diethylbenzo-1,2-diselenete
(<b>4</b>), was prepared by the reaction of 4,5-(<i>o</i>-xylylenediseleno)-3,6-diethylphthalonitrile (<b>3</b>) with
aluminum chloride in toluene. X-ray crystallographic analysis demonstrated
that <b>4</b> contains a trapezoidal diselenide ring rather
than a benzo-1,2-diselenone structure. In crystal form, <b>4</b> undergoes self-assembly and generates structures based on layered
molecular sheets since the unit cell contains only one molecule. While
the cyclic voltammogram of <b>4</b> exhibited only one irreversible
peak (<i>E</i><sub>p</sub> = 1.59 V) during oxidation and
two quasireversible couples during reduction, three peaks were observed
in the differential pulse voltammogram of the reduction couples (<i>E</i><sub>1/2</sub> = −1.19, −0.75, and −0.69
V). Although a THF solution of <b>4</b> in the presence of sodium
metal was EPR silent, various signals were readily observed in its <sup>1</sup>H, <sup>13</sup>C, and <sup>77</sup>Se NMR spectra. Molecular
orbital calculations for <b>4</b> demonstrated that the HOMO
orbital is primarily localized at the two selenium atoms and four
of the benzene carbon atoms while the LUMO orbital is situated solely
on the diselenete ring. It appears that the HOMO and LUMO orbitals
of <b>4</b> receive significant stabilization from the nitrile
groups compared to the level of stabilization in the unsubstituted
benzo-1,2-diselenete (<b>BDS</b>). The reaction of <b>4</b> with tetrakis(triphenylphosphine)palladium in benzene was
found to produce a dinuclear palladium complex (<b>8</b>), and
the structure of this complex was determined by X-ray crystallographic
analysis. The central four membered ring of <b>8</b> consists
of the Pd1, Se2, Pd2, and Se3 atoms and is not planar but rather adopts
a folded arrangement
Prediction models for in-hospital deaths of patients with COVID-19 using electronic healthcare data
Many models for predicting various disease prognoses have achieved high performance without laboratory test results. However, whether laboratory test results can improve performance remains unclear. This study aimed to investigate whether laboratory test results improve the model performance for coronavirus disease 2019 (COVID-19). Prediction models were developed using data from the electronic healthcare record database in Japan. Patients aged ≥18 years hospitalized for COVID-19 after February 11, 2020, were included. Their age, sex, comorbidities, laboratory test results, and number of days from February 11, 2020, were collected. We developed a logistic regression, XGBOOST, random forest, and neural network analysis and compared the performance with and without laboratory test results. The performance of predicting in-hospital death was evaluated using the area under the curve (AUC). Data from 8,288 hospitalized patients (females, 46.5%) were analyzed. The median patient age was 71 years. A total of 6,630 patients were included in the training dataset, and 312 (4.7%) died. In the logistic regression model, the area under the curve was 0.88 (95% confidence interval [CI] = 0.83–0.93) and 0.75 (95% CI = 0.68–0.81) with and without laboratory test results, respectively. The performance was not fundamentally different between the model types, and the laboratory test results improved the performance in all cases. The variables useful for prediction were blood urea nitrogen, albumin, and lactate dehydrogenase. Laboratory test results, such as blood urea nitrogen, albumin, and lactate dehydrogenase levels, along with background information, helped estimate the prognosis of patients hospitalized for COVID-19.</p
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