Arbitrary cross-section SEM-cathodoluminescence imaging of growth sectors and local carrier concentrations within micro-sampled semiconductor nanorods

Future one-dimensional electronics require single-crystalline semiconductor free-standing nanorods grown with uniform electrical properties. However, this is currently unrealistic as each crystallographic plane of a nanorod grows at unique incorporation rates of environmental dopants, which forms axial and lateral growth sectors with different carrier concentrations. Here we propose a series of techniques that micro-sample a free-standing nanorod of interest, fabricate its arbitrary cross-sections by controlling focused ion beam incidence orientation, and visualize its internal carrier concentration map. ZnO nanorods are grown by selective area homoepitaxy in precursor aqueous solution, each of which has a (0001):+c top-plane and six {1–100}:m side-planes. Near-band-edge cathodoluminescence nanospectroscopy evaluates carrier concentration map within a nanorod at high spatial resolution (60 nm) and high sensitivity. It also visualizes +c and m growth sectors at arbitrary nanorod cross-section and history of local transient growth events within each growth sector. Our technique paves the way for well-defined bottom-up nanoelectronics

"Electronic Procurement networks and Parts Transaction Systems: A Case of the Automobile Industry"(in Japanese)

Inter-firm information systems in the automobile industry have evolved from firm-specific networks to industrial standard networks and further to internet. This paper examines how electronic parts procurement systems in the automobile industry affected its patterns of inter-firm transactions through empirical studies on information networks, transaction systems, and architectural characteristics of automobile parts. We argue that choice of a certain parts transaction system tends to affect choice of the mode of information system that might best fit the transaction information between the firms. Conversely, once a particular type of information is chosen, the mode of information exchanges, patterns of competitions between suppliers and transaction systems would also be changed. In this way, inter-firm information systems, transaction patterns, and architectures of the pars co-evolve through dynamic interactions among them.

Asymptotic Symmetry and the General Black Hole Solution in Ads_3 Gravity

We describe the Brown-Henneaux asymptotic symmetry of the general black holes in the Chern-Simons gauge theory of the gauge group $SL(2;{\bf R})_L\times SL(2;{\bf R})_R$. We make it clear that the vector-like subgroup $SL(2; {\bf R})_{L+R}$ plays an essential role in describing the asymptotic symmetry consistently. We find a quite general black hole solution in the $AdS_3$ gravity theory. The solution is specified by an infinite number of conserved quantities which constitute a family of mapping from $S^1$ to the gauge group. The BTZ black hole is one of the simplest case.Comment: 19 pages, no figur

Cardiosphere-derived exosomal microRNAs for myocardial repair in pediatric dilated cardiomyopathy

Although cardiosphere-derived cells (CDCs) improve cardiac function and outcomes in patients with single ventricle physiology, little is known about their safety and therapeutic benefit in children with dilated cardiomyopathy (DCM). We aimed to determine the safety and efficacy of CDCs in a porcine model of DCM and translate the preclinical results into this patient population. A swine model of DCM using intracoronary injection of microspheres created cardiac dysfunction. Forty pigs were randomized as preclinical validation of the delivery method and CDC doses, and CDC-secreted exosome (CDCex)–mediated cardiac repair was analyzed. A phase 1 safety cohort enrolled five pediatric patients with DCM and reduced ejection fraction to receive CDC infusion. The primary endpoint was to assess safety, and the secondary outcome measure was change in cardiac function. Improved cardiac function and reduced myocardial fibrosis were noted in animals treated with CDCs compared with placebo. These functional benefits were mediated via CDCex that were highly enriched with proangiogenic and cardioprotective microRNAs (miRNAs), whereas isolated CDCex did not recapitulate these reparative effects. One-year follow-up of safety lead-in stage was completed with favorable profile and preliminary efficacy outcomes. Increased CDCex-derived miR-146a-5p expression was associated with the reduction in myocardial fibrosis via suppression of proinflammatory cytokines and transcripts. Collectively, intracoronary CDC administration is safe and improves cardiac function through CDCex in a porcine model of DCM. The safety lead-in results in patients provide a translational framework for further studies of randomized trials and CDCex-derived miRNAs as potential paracrine mediators underlying this therapeutic strategy

Effectiveness of jet location on mixing characteristics inside a cavity in supersonic flow

The incorporation of cavities within supersonic combustion chambers is an effective means of slowing down the flow for fuel injection and consequent stable combustion. Understanding the flow physics associated with such flows, especially with the injection of a gas to replicate fuel injection, are essential for the optimum design of supersonic propulsion mechanisms. An experimental investigation was performed on a rectangular open cavity with upstream injection model in a Mach number of 1.9 using a trisonic indraft wind tunnel. A rectangular open cavity of dimensions L/D = 5, 100 mm in length (L) and 20 mm deep (D), was adopted, and it was embedded into the lower wall of the test section. An air jet with a jet-to-freestream momentum flux ratio of J = 1.2, 2.7 and 5.3 was injected upstream of the cavity. To evaluate the effect on mixing and flow stability the jet position, measured from the front edge of the cavity, was varied between 0.1L and 1L. The flow field was visualized using schlieren photography, particle image velocimetry, and oil flow measurements. It is found that the mixing characteristic within the cavity when the jet is positioned 0.1L is enhanced independent on the J value because the turbulence intensity of the flow velocity within the cavity is strongly influenced by the jet interaction which lifted the flow from the floor of the cavity compared to the other jet positions. However, the flow over the cavity is unstable at all jet positions. The separation shock formed at the front edge of the cavity oscillates significantly for the case where the jet is located at 0.1L because the separation shock location coincides with the compression shock behind the jet

A Substellar Companion to Pleiades HII 3441

We find a new substellar companion to the Pleiades member star, Pleiades HII 3441, using the Subaru telescope with adaptive optics. The discovery is made as part of the high-contrast imaging survey to search for planetary-mass and substellar companions in the Pleiades and young moving groups. The companion has a projected separation of 0".49 +/- 0".02 (66 +/- 2 AU) and a mass of 68 +/- 5 M_J based on three observations in the J-, H-, and K_S-band. The spectral type is estimated to be M7 (~2700 K), and thus no methane absorption is detected in the H band. Our Pleiades observations result in the detection of two substellar companions including one previously reported among 20 observed Pleiades stars, and indicate that the fraction of substellar companions in the Pleiades is about 10.0 +26.1/-8.8 %. This is consistent with multiplicity studies of both the Pleiades stars and other open clusters.Comment: Main text (14 pages, 4 figures, 4 tables), and Supplementary data (8 pages, 3 tables). Accepted for Publications of Astronomical Society of Japa