Restaurant recommendation system (RRS)

Discusses the development of an online restaurant recommendation system that allows users to search for restaurants in the Los Angeles area. The user can retrieve restaurant information including, name, type of restaurant, address, phone number, rating, prices and map. By logging in, users can also give their own recommendations and rate restaurants. The system also provides functions that allow a system a system administrator to manage the contents of the site. The project is based on Java Server Pages (JSP) language, Java Server Programming, which is a server side scripting language. Utilizes MySQL to maintain persistent data and Tomcat as a web system server

Photo-patternable gelatin as protection layers in surface micromachinings

This paper describes a newly developed low-temperature photo-patternable Gelatin technology that is useful to produce a thick (greater than 10 microns) Gelatin protecting and strengthening layer for weak MEMS micro-structures. Example demonstrated here is the Gelatin process integrated with the Parylene MEMS technology. What is reported here is the complete processing details and formulae that allow anyone to use Gelatin like photo-resist. We find that it is a chemical-resistant and mechanical-robust material for MEMS applications

Turbulence spectra in the buoyancy subrange of thermally stratified shear flows

CER68-69JTL21.February 1969.Originally presented as the author's thesis, Colorado State University.Includes bibliographical references (pages 94-97).Prepared under Office of Naval Research, project no. NR 062-414/6-6-68(Code 438), U.S. Department of Defense.A generalized eddy-viscosity approximation is used to study the turbulence spectra of thermally stratified shear flows. For a stationary process in the wave number range investigated--the buoyancy subrange--under the assumption of local homogeneity of the flow, two governing spectral equations with six unknowns are derived from the equations of motion and energy. In order to reduce the number of unknowns to two so that the spectral equations can be solved, a generalized eddy-viscosity is used for expressing the integrated forms of the inertial transfers of energy and temperature inhomogeneity, the shear stress and vertical heat flux in terms of velocity spectrum ¢(k) and temperature spectrum ¢TT(k). Asymptotic solutions are obtained in the buoyancy subrange where the local production and local dissipation of turbulent energy is negligible as compared to the inertial transfer and vertical heat flux terms when the flow conditions satisfy the criterion ε|dT'/dz| << N g/T' or g/T'. |dT'/dz| << N/ε.(g/T)^2. In the buoyancy subrange of stably stratified turbulent flow, the power law for the velocity and temperature spectra is not universal but varies with the flow conditions in the way ¢(k) ~ k^n and ¢TT(k) ~ k^m where 11/5 ≥ n ≥ -3 and -1 ≥ m ≥ -7/5. According to the measurements of velocity spectra in the atmosphere (Pinus and Schcherbakova, 1966; Myrup, 1968), the dependence of the power law on the flow conditions was confirmed. The solutions of Bolgiano (1959) and Luialey-Shur (1964) are only two particular cases of the present results under cert ain flow conditions. In the case of the unstably stratified turbulent flow, the velocity spectrum exhibits a hump in the buoyancy subrange as a result of the energy input from the temperature field to the velocity field. In the left side of this hump the velocity spectrum approaches a +1 slope and the temperature spectrum shows a -3 slope. The measurements of the velocity spectra in the atmosphere (Ivanov and Ordanovich, 1967) confirms this tendency.Under contract no. N00014-68-A-0493-0001

Stability of Positively Charged Solutes in Water: A Transition from Hydrophobic to Hydrophilic

To improve the description of solvation thermodynamics of biomolecules, we report here the dependence of solvation on the curvature and surface charge of positively charged solutes in water based on extensive molecular dynamics simulations analyzed using the two-phase thermodynamic method. At a surface charge of +0.4e, the compensating forces of favorable electrostatic stabilization and entropic destabilization cancel almost exactly, representing a molecular crossover point from hydrophobic to hydrophilic behavior, independent of curvature. These results suggest that one should include charge-dependent entropic corrections to continuum models aimed at predicting the solvation free energies of large biomolecules

Marching velocity of capillary meniscuses in microchannels

[[abstract]]This paper describes a new method and an analytical model for characterizing the surface energy inside a microchannel using the measurement of the marching velocity of a capillary meniscus. This method is based on the fact that surface tension of a liquid meniscus in a hydrophilic case produces pressure to pull liquid into the channel and the velocity of the meniscus is related to the surface energy. Both Parylene and silicon nitride microchannels with different surface conditions were fabricated to perform the liquid-filling experiments. It is shown that our model agrees well with the data and this is a valid method.[[conferencetype]]國際[[conferencedate]]20020120~20020124[[iscallforpapers]]Y[[conferencelocation]]Las Vegas, NV, US

Brain Network Changes in Fatigued Drivers: A Longitudinal Study in a Real-World Environment Based on the Effective Connectivity Analysis and Actigraphy Data

The analysis of neurophysiological changes during driving can clarify the mechanisms of fatigue, considered an important cause of vehicle accidents. The fluctuations in alertness can be investigated as changes in the brain network connections, reflected in the direction and magnitude of the information transferred. Those changes are induced not only by the time on task but also by the quality of sleep. In an unprecedented 5-month longitudinal study, daily sampling actigraphy and EEG data were collected during a sustained-attention driving task within a near-real-world environment. Using a performance index associated with the subjects' reaction times and a predictive score related to the sleep quality, we identify fatigue levels in drivers and investigate the shifts in their effective connectivity in different frequency bands, through the analysis of the dynamical coupling between brain areas. Study results support the hypothesis that combining EEG, behavioral and actigraphy data can reveal new features of the decline in alertness. In addition, the use of directed measures such as the Convergent Cross Mapping can contribute to the development of fatigue countermeasure devices

Photo-patternable gelatin as protection layers in surface micromachinings

This paper describes a newly developed low-temperature photo-patternable Gelatin technology that is useful to produce a thick (greater than 10 microns) Gelatin protecting and strengthening layer for weak MEMS micro-structures. Example demonstrated here is the Gelatin process integrated with the Parylene MEMS technology. What is reported here is the complete processing details and formulae that allow anyone to use Gelatin like photo-resist. We find that it is a chemical-resistant and mechanical-robust material for MEMS applications

Overexpression of Nuclear Protein Kinase CK2 α Catalytic Subunit (CK2α) as a Poor Prognosticator in Human Colorectal Cancer

BACKGROUND: Colorectal cancer (CRC) is one of the most common malignancies but the current therapeutic approaches for advanced CRC are less efficient. Thus, novel therapeutic approaches are badly needed. The purpose of this study is to investigate the involvement of nuclear protein kinase CK2 α subunit (CK2α) in tumor progression, and in the prognosis of human CRC. METHODOLOGY/PRINCIPAL FINDINGS: Expression levels of nuclear CK2α were analyzed in 245 colorectal tissues from patients with CRC by immunohistochemistry, quantitative real-time PCR and Western blot. We correlated the expression levels with clinicopathologic parameters and prognosis in human CRC patients. Overexpression of nuclear CK2α was significantly correlated with depth of invasion, nodal status, American Joint Committee on Cancer (AJCC) staging, degree of differentiation, and perineural invasion. Patients with high expression levels of nuclear CK2α had a significantly poorer overall survival rate compared with patients with low expression levels of nuclear CK2α. In multi-variate Cox regression analysis, overexpression of nuclear CK2α was proven to be an independent prognostic marker for CRC. In addition, DLD-1 human colon cancer cells were employed as a cellular model to study the role of CK2α on cell growth, and the expression of CK2α in DLD-1 cells was inhibited by using siRNA technology. The data indicated that CK2α-specific siRNA treatment resulted in growth inhibition. CONCLUSIONS/SIGNIFICANCE: Taken together, overexpression of nuclear CK2α can be a useful marker for predicting the outcome of patients with CRC

Marching velocity of capillary meniscuses in microchannels

This paper describes a new method and an analytical model for characterizing the surface energy inside a microchannel using the measurement of the marching velocity of a capillary meniscus. This method is based on the fact that surface tension of a liquid meniscus in a hydrophilic case produces pressure to pull liquid into the channel and the velocity of the meniscus is related to the surface energy. Both Parylene and silicon nitride microchannels with different surface conditions were fabricated to perform the liquid-filling experiments. It is shown that our model agrees well with the data and this is a valid method