REPORT ON THE COST OF CRIME

The full title of the twelfth report of the National Commission on Law Observance and Enforcement is Report on the Cost of Crime and Criminal Justice in the United States. A more descriptive title, suggested by the actual content of the report, would be The Economic Consequences of Crime. The report constitutes a volume of 657 pages, of which the report proper covers 453 pages, and various appendices make up the balance. For the hasty reader the most essential parts are the first eight pages, constituting the Commission\u27s comments, and the summary and recommendations, of Messrs. Goldthwaite H. Dorr and Sidney P. Simpson who prepared the report. In the preparation of the report these gentlemen were assisted by numbers of experts in the fields of law, political science, sociology, and accounting, and by literally hundreds of citizens, working for the most part without compensation, who furnished the underlying data. In spite of the lack of time, lack of funds, lack of trained investigators, and, perhaps most serious of all, lack of uniform and detailed statistics, it must be said that the Report accomplishes that which must have been its chief purpose, namely, the calling of public attention with vigor and clarity to the exceedingly great importance of crime just from the standpoint of the economic loss and waste which it entails

Flotation

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HECKERT, J. BROOKS. The Analysis and Control of Distribution Costs for Sales Executives and Accountants. Pp. xvii, 420. New York: Ronald Press Co., 1940. $5.00

Peer Reviewedhttp://deepblue.lib.umich.edu/bitstream/2027.42/66973/2/10.1177_000271624020900143.pd

Distribution cost accounting for wholesaling

Recent legislation, such as the Robinson-Patman Act, has brought to the fore the need for improved distribution cost accounting. The Bureau, in response to demands from business for assistance in this field, has prepared this study of distribution cost procedure for the field of wholesaling. This important field includes the great variety of wholesale houses, and the newer types of wholesaling engaged in by direct distributors and direct purchasers

Regional differences in APD restitution can initiate wavebreak and re-entry in cardiac tissue: A computational study

Background Regional differences in action potential duration (APD) restitution in the heart favour arrhythmias, but the mechanism is not well understood. Methods We simulated a 150 × 150 mm 2D sheet of cardiac ventricular tissue using a simplified computational model. We investigated wavebreak and re-entry initiated by an S1S2S3 stimulus protocol in tissue sheets with two regions, each with different APD restitution. The two regions had a different APD at short diastolic interval (DI), but similar APD at long DI. Simulations were performed twice; once with both regions having steep (slope > 1), and once with both regions having flat (slope < 1) APD restitution. Results Wavebreak and re-entry were readily initiated using the S1S2S3 protocol in tissue sheets with two regions having different APD restitution properties. Initiation occurred irrespective of whether the APD restitution slopes were steep or flat. With steep APD restitution, the range of S2S3 intervals resulting in wavebreak increased from 1 ms with S1S2 of 250 ms, to 75 ms (S1S2 180 ms). With flat APD restitution, the range of S2S3 intervals resulting in wavebreak increased from 1 ms (S1S2 250 ms), to 21 ms (S1S2 340 ms) and then 11 ms (S1S2 400 ms). Conclusion Regional differences in APD restitution are an arrhythmogenic substrate that can be concealed at normal heart rates. A premature stimulus produces regional differences in repolarisation, and a further premature stimulus can then result in wavebreak and initiate re-entry. This mechanism for initiating re-entry is independent of the steepness of the APD restitution curve

Integrated Airframe Technology: The Future of Advanced Composites

The challenge for advanced composites in integrated airframe technology is that: airframes must provide ever increasing performance at an affordable cost; reduce costs as compared to current airframe technology; and integration of design and manufacturing. The trend in technology is that a gap exists between the potential of advanced composites and our ability to effectively utilize them (cost/weight)

The Role of Whey Acidic Protein Four-Disulfide-Core Proteins in Respiratory Health and Disease

Abstract Members of the whey acidic protein (WAP) or WAP four-disulfide-core (WFDC) family of proteins are a relatively under-explored family of low molecular weight proteins. The two most prominent WFDC proteins, secretory leukocyte protease inhibitor (SLPI) and elafin (or the precursor, trappin-2), have been shown to possess multiple functions including anti-protease, anti-bacterial, anti-viral and anti-inflammatory properties. It is therefore of no surprise that both SLPI and elafin/trappin-2 have been developed as potential therapeutics. Given the abundance of SLPI and elafin/trappin-2 in the human lung, most work in the area of WFDC research has focused on the role of WFDC proteins in protecting the lung from proteolytic attack. In this review, we will outline the current evidence regarding the expanding role of WFDC protein function with a focus on WFDC activity in lung disease as well as emerging data regarding the function of some of the more recently described WFDC proteins.</jats:p