CIRCULATING IMMUNE-COMPLEXES IN SYSTEMIC AMYLOIDOSIS

WOS: A1981MF98300005PubMed ID: 7341031

Circulating immune complexes in systemic amyloidosis

PubMedID: 7341031Serum immune complexes were measured in patients with immunocytic amyloidosis (8 patients), reactive amyloidosis (6 patients), and amyloidosis secondary to familial mediterranean fever (11 patients). 125I-Clq-binding method and 4% PEG precipitation methods were employed for immune complex determinations. Immune complexes were found in three patients with immunocytic amyloidosis, in all cases of reactive amyloidosis and in nine with amyloidosis secondary to FMF. Immunoglobulins found in the complexes were mainly IgG and IgM in all three groups. © 1981

The interaction of artificial saliva with heat-pressed all-ceramic materials.

1st Annual Meeting of the International-Association-for-Dental-Research -- SEP 18, 2002 -- Cardiff, WALESWOS: 00018907830294

Determination of elemental composition of substance lost following wear of all-ceramic materials

WOS: 000183116000009PubMed ID: 12854789Purpose: The aim of this study was to test the possible elemental release of four different all-ceramic materials in a wear machine to predict results about their long-term behavior in the oral environment. Materials and Methods: Four different all-ceramic materials with different chemical compositions were selected for the wear testing. A total of 20 cylindric samples, five for each ceramic group, were prepared according to the manufacturers' instructions. These were subjected to two-body wear testing in an artificial saliva medium under a covered unit with a computer-operated wear machine. The artificial saliva Solutions for each material were analyzed for the determination of amounts of sodium, potassium, calcium, magnesium, and lithium elements released from the glass-ceramic materials. The differences between and within groups were statistically analyzed with a one-way ANOVA, followed by Duncan tests. Results: The statistical analyses revealed no significant differences among Na, K, Ca, or Mg levels (P greater than or equal to .05) released from the leucite-reinforced groups, while there was a significant (P < .05) increase in Li release from the lithium disilicate group. Conclusion: Considerable element release to the artifical saliva medium was demonstrated in short-term wear testing. The lithia-based ceramic was more prone to Li release when compared with other elements and materials

Diagnostic-Value Of Bone-Marrow Biopsy In Patients With Renal-Disease Secondary To Familial Mediterranean Fever

Systemic AA type amyloidosis with renal involvement is the major cause of morbidity and mortality in patients with familial Mediterranean fever (FMF). A histopathological examination is essential to achieve a definite diagnosis in systemic amyloidosis. The diagnostic yield of the procedure varies according to the biopsy site and renal biopsy has the highest yield. On the other hand this procedure has its own complications and requires hospitalization of the patient. Alternative biopsy sites have been proposed with varying degrees of sensitivity and morbidity to reduce the morbidity and mortality of solid organ biopsies. We performed bone marrow biopsies in 39 patients with FMF who had different stages of renal disease. Thirty-one (79.5%) of the 39 specimens showed significant perivascular amyloid infiltration when stained with crystal violet and Congo red. An immunoperoxidase stain with a monoclonal antibody proved that these deposits were AA type amyloid. We suggest that bone marrow biopsy can be utilized for a safe and quick diagnosis of systemic amyloidosis in patients with FMF and renal disease.Wo

Hypernatraemia And Polyuria Due To High-Dose Colchicine In A Suicidal Patient

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