311 research outputs found

    Accretion of a satellite onto a spherical galaxy. II. Binary evolution and orbital decay

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    We study the dynamical evolution of a satellite orbiting outside of a companion spherical galaxy. The satellite is subject to a back-reaction force resulting from the density fluctuations excited in the primary stellar system. We evaluate this force using the linear response theory developed in Colpi and Pallavicini (1997). The force is computed in the reference frame comoving with the primary galaxy and is expanded in multipoles. To capture the relevant features of the physical process determining the evolution of the detached binary, we introduce in the Hamiltonian the harmonic potential as interaction potential among stars. The dynamics of the satellite is computed self-consistently. We determine the conditions for tidal capture of a satellite from an asymptotic free state. If the binary comes to existence as a bound pair, stability against orbital decay is lost near resonance. The time scale of binary coalescence is computed as a function of the eccentricity and mass ratio. In a comparison with Weinberg's perturbative technique we demonstrate that pinning the center of mass of the galaxy would induce a much larger torque on the satellite.Comment: 13 pages, Tex,+ 10 .ps figures Submitted to The Astrophysical Journa

    Dynamical friction and the evolution of satellites in virialized halos: the theory of linear response

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    The evolution of a small satellite inside a more massive truncated isothermal spherical halo is studied using both the Theory of Linear Response for dynamical friction and N-Body simulations. The analytical approach includes the effects of the gravitational wake, of the tidal deformation and the shift of the barycenter of the primary, so unifying the local versus global interpretation of dynamical friction. Sizes, masses, orbital energies and eccentricities are chosen as expected in hierarchical clustering models. We find that in general the drag force in self-gravitating backgrounds is weaker than in uniform media and that the orbital decay is not accompanied by a significant circularization. We also show that the dynamical friction time scale is weakly dependent on the initial circularity. We provide a fitting formula for the decay time that includes the effect of mass and angular momentum loss. Live satellites with dense cores can survive disruption up to an Hubble time within the primary, notwithstanding the initial choice of orbital parameters. Dwarf spheroidal satellites of the Milky Way, like Sagittarius A and Fornax, have already suffered mass stripping and, with their present masses, the sinking times exceed 10 Gyr even if they are on very eccentric orbits.Comment: 27 pages including 9 figures. Accepted for publication in the Astrophysical Journal. Part 2, issue November 10 1999, Volume 52

    Three-dimensional carbon nanotube yarn based solid state solar cells with multiple sensitizers exhibit high energy conversion efficiency

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    Fiber-type dye sensitized solar cells that are non-metallic, flexible, and thread-like in structure have many potential military and functional textile applications. With the use of quantum dots (QD), exciton transfer facilitators (Phenyl-C61-butyric acid methyl ester-PCBM) and Poly(3-hexylthiophene-2,5-diyl-P3HT), and careful preparation of the TiO2 oxide layer deposited on the carbon fiber working electrode, an optimized efficiency of 7.6% was obtained. Carbon nanotube yarn (CNTY) was used to prepare both the working and counter electrodes of the fabricated cells. TiCl4 annealing of the TiO2 layer was carried out and the resulting oxide layer morphology was found to be very uniform. The quantum dots, cadmium sulfide (CdS) and cadmium selenide (CdSe), were deposited directly onto the surface of the nanoporous oxide layer using chemical bath deposition (CBD). Also, the P3HT and PCBM were applied and deposited via CBD on the working electrode as a bulk heterojunction material. Potentiometric characterization of the prepared cells performed at different cell lengths and showed that the maximum efficiency was obtained for cells approximately 3.5 cm in length. Photovoltaic performance of these solid state three dimensional cells was also carried out for different cell configurations

    Advanced cotton fibers exhibit efficient photocatalytic self-cleaning and antimicrobial activity

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    Functional cotton fibers have a wide range of applications in domestic, commercial, and military settings, and so enhancing the properties of these materials can yield substantial benefits. Herein, we report the creation of functional fibers that are self-cleaning, anti-microbial, and protective against UV radiation. A uniform, and high surface area films of TiO2 were deposited on cotton fibers and gold/silver nanoparticles were directly incorporated on the nanostructured TiO2 surface. The synthetic method is simple and the produced TiO2 film is homogenous and the nanoparticles were shown to be effectively distributed on the surface using a simple photocatalytic reduction method. The Ag/Au-TiO2 coated fibers was morphologically characterized using atomic force microscopy (AFM) and scanning electron microscopy/energy dispersive X-ray spectroscopy (SEM/EDS), and the self-cleaning properties of noble metal nanoparticle/TiO2 coated fibers were demonstrated by repeated staining followed by exposure to simulated solar light. The 1 mM Ag-TiO2 coated fabric was observed to have the largest improvement in rate of stain extinction compared to the untreated fibers with a methylene blue stain, and the 1 mM Au-TiO2 coated fibers were observed to have the largest improvement versus untreated fibers when stained with Congo red. The fibers maintained consistent photocatalytic activity over multiple cycles, and the resistance of the Ag/Au-TiO2 coated cotton to degradation was verified using Fourier transform infrared spectroscopy (FTIR). An efficient anti-microbial activity of the fibers was confirmed by exposure of the fibers to bacterial culture (Escherichia Coli) and direct observation of antimicrobial activity

    Social, environmental and psychological factors associated with objective physical activity levels in the over 65s

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    Objective: To assess physical activity levels objectively using accelerometers in community dwelling over 65 s and to examine associations with health, social, environmental and psychological factors. Design: Cross sectional survey. Setting: 17 general practices in Scotland, United Kingdom. Participants: Random sampling of over 65 s registered with the practices in four strata young-old (65–80 years), old-old (over 80 years), more affluent and less affluent groups. Main Outcome Measures: Accelerometry counts of activity per day. Associations between activity and Theory of Planned Behaviour variables, the physical environment, health, wellbeing and demographic variables were examined with multiple regression analysis and multilevel modelling. Results: 547 older people (mean (SD) age 79(8) years, 54% female) were analysed representing 94% of those surveyed. Accelerometry counts were highest in the affluent younger group, followed by the deprived younger group, with lowest levels in the deprived over 80 s group. Multiple regression analysis showed that lower age, higher perceived behavioural control, the physical function subscale of SF-36, and having someone nearby to turn to were all independently associated with higher physical activity levels (R2 = 0.32). In addition, hours of sunshine were independently significantly associated with greater physical activity in a multilevel model. Conclusions: Other than age and hours of sunlight, the variables identified are modifiable, and provide a strong basis for the future development of novel multidimensional interventions aimed at increasing activity participation in later life.Publisher PDFPeer reviewe

    Drag on a satellite moving across a spherical galaxy. I. Tidal and frictional forces in shortlived encounters

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    We derive a formalism, within the theory of linear response, for the analysis of the interaction of a satellite (the perturber) with a spherical galaxy whose equilibrium is described by a one-particle distribution function. We compute the formal expression of the force on the satellite including the self-gravity of the stars and the shift of the stellar center of mass. We apply the perturbative technique to the case of a satellite moving at high speed across a stellar system and find a natural decomposition of the force into a global component resulting from the tidal interaction and a component that is related to dynamical friction. When the satellite orbits outside the galaxy, we derive the force in the impulse approximation. In penetrating shortlived encounters, the wake excited in the density field is responsible for most of the deceleration. We find that dynamical friction rises from a memory effect involving only those stars perturbed along the path. The force can be written in terms of an effective Coulomb logarithm which now depends on the dynamical history. It is derived for two simple equilibrium density distributions. In the case of a homogeneous cloud, we compute the total energy loss: Tides excited by the satellite in the galaxy reduce the value of the energy loss by friction.Comment: 22 pages, Tex + 5 .ps figures Submitted to The Astrophysical Journa

    Learning to Learn: Theta Oscillations Predict New Learning, which Enhances Related Learning and Neurogenesis

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    Animals in the natural world continuously encounter learning experiences of varying degrees of novelty. New neurons in the hippocampus are especially responsive to learning associations between novel events and more cells survive if a novel and challenging task is learned. One might wonder whether new neurons would be rescued from death upon each new learning experience or whether there is an internal control system that limits the number of cells that are retained as a function of learning. In this experiment, it was hypothesized that learning a task that was similar in content to one already learned previously would not increase cell survival. We further hypothesized that in situations in which the cells are rescued hippocampal theta oscillations (3–12 Hz) would be involved and perhaps necessary for increasing cell survival. Both hypotheses were disproved. Adult male Sprague-Dawley rats were trained on two similar hippocampus-dependent tasks, trace and very-long delay eyeblink conditioning, while recording hippocampal local-field potentials. Cells that were generated after training on the first task were labeled with bromodeoxyuridine and quantified after training on both tasks had ceased. Spontaneous theta activity predicted performance on the first task and the conditioned stimulus induced a theta-band response early in learning the first task. As expected, performance on the first task correlated with performance on the second task. However, theta activity did not increase during training on the second task, even though more cells were present in animals that had learned. Therefore, as long as learning occurs, relatively small changes in the environment are sufficient to increase the number of surviving neurons in the adult hippocampus and they can do so in the absence of an increase in theta activity. In conclusion, these data argue against an upper limit on the number of neurons that can be rescued from death by learning

    HS1, a Lyn Kinase Substrate, Is Abnormally Expressed in B-Chronic Lymphocytic Leukemia and Correlates with Response to Fludarabine-Based Regimen

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    In B-Chronic Lymphocytic Leukemia (B-CLL) kinase Lyn is overexpressed, active, abnormally distributed, and part of a cytosolic complex involving hematopoietic lineage cell-specific protein 1 (HS1). These aberrant properties of Lyn could partially explain leukemic cells’ defective apoptosis, directly or through its substrates, for example, HS1 that has been associated to apoptosis in different cell types. To verify the hypothesis of HS1 involvement in Lyn-mediated leukemic cell survival, we investigated HS1 protein in 71 untreated B-CLL patients and 26 healthy controls. We found HS1 overexpressed in leukemic as compared to normal B lymphocytes (1.38±0.54 vs 0.86±0.29, p<0.01), and when HS1 levels were correlated to clinical parameters we found a higher expression of HS1 in poor-prognosis patients. Moreover, HS1 levels significantly decreased in ex vivo leukemic cells of patients responding to a fludarabine-containing regimen. We also observed that HS1 is partially localized in the nucleus of neoplastic B cells. All these data add new information on HS1 study, hypothesizing a pivotal role of HS1 in Lyn-mediated modulation of leukemic cells’ survival and focusing, one more time, the attention on the BCR-Lyn axis as a putative target for new therapeutic strategies in this disorder

    Binary classification of dyslipidemia from the waist-to-hip ratio and body mass index: a comparison of linear, logistic, and CART models

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    BACKGROUND: We sought to improve upon previously published statistical modeling strategies for binary classification of dyslipidemia for general population screening purposes based on the waist-to-hip circumference ratio and body mass index anthropometric measurements. METHODS: Study subjects were participants in WHO-MONICA population-based surveys conducted in two Swiss regions. Outcome variables were based on the total serum cholesterol to high density lipoprotein cholesterol ratio. The other potential predictor variables were gender, age, current cigarette smoking, and hypertension. The models investigated were: (i) linear regression; (ii) logistic classification; (iii) regression trees; (iv) classification trees (iii and iv are collectively known as "CART"). Binary classification performance of the region-specific models was externally validated by classifying the subjects from the other region. RESULTS: Waist-to-hip circumference ratio and body mass index remained modest predictors of dyslipidemia. Correct classification rates for all models were 60–80%, with marked gender differences. Gender-specific models provided only small gains in classification. The external validations provided assurance about the stability of the models. CONCLUSIONS: There were no striking differences between either the algebraic (i, ii) vs. non-algebraic (iii, iv), or the regression (i, iii) vs. classification (ii, iv) modeling approaches. Anticipated advantages of the CART vs. simple additive linear and logistic models were less than expected in this particular application with a relatively small set of predictor variables. CART models may be more useful when considering main effects and interactions between larger sets of predictor variables
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