Environment-hygienic quality of primary and secondary building materials in relation to re-use end soil protection

Abstract niet beschikbaarBij the industry some sticking points are set in the current draft General Administrative Order on Building materials dd/26/9/91 (oBB). These are: insufficient balance between re-use and soil protection it appears that the standard values from the draft are unofficially in charge. As a result the application of a number of building materials are decreasing which are allowed at this moment the standard values of leaching are based on a short experience with the leaching test in the laboratory. The advices concerning the standard values for composition didn't come to an unanimous opinion. The directorate asked the National Institute for Public health and Environmental Protection (RIVM): to give a list of building materials which could be applied according to the draft standard values of the oBB. To give an evaluation and explanation of the calculations for the standard values. To give the consequences of the evaluated standard values for the re- use of building materials. To give an evaluation of the standard values for composition.DGM/BO: DGM/

Development of severe bronchopulmonary dysplasia is associated with alterations in fecal volatile organic compounds

BackgroundAim of this study was to evaluate the potential of fecal volatile organic compounds (VOC), obtained by means of an electronic nose device (Cyranose 320®), as early non-invasive biomarker for BPD.MethodsIn this nested case-control study performed at three Neonatal Intensive Care Units, fecal samples obtained at postnatal age of 7, 14, 21 and 28 days, from preterm infants with severe BPD, were compared with fecal VOC profiles from matched controls. Microbiota analysis was performed by means of IS-pro technique on fecal samples collected at 28 days postnatally.ResultsVOC profiles of infants developing severe BPD (n=15) could be discriminated from matched controls (n=15) at postnatal age of 14 days (area under the curve [±95% confidence interval], p-value, sensitivity, specificity; 0.72 [0.54-0.90], 0.040, 60.0%, 73.3%), 21 days (0.71 [0.52-0.90], 0.049, 66.7%, 73.3%) and 28 days (0.77 [0.59-0.96], 0.017, 69.2%, 69.2%), but not at 7 days. Intestinal microbiota did not differ between BPD subjects and controls.ConclusionFecal VOC profiles of infants developing BPD could be differentiated from controls at postnatal day 14, 21 and 28. VOC differences could not be directed to intestinal microbiota alterations but presumably reflect local and systemic metabolic and inflammatory pathways associated with BPD.Pediatric Research accepted article preview online, 20 October 2017. doi:10.1038/pr.2017.26

Long-term Outcomes of Paediatric Patients Admitted With Acute Severe Colitis-A Multicentre Study From the Paediatric IBD Porto Group of ESPGHAN

Acute severe colitis (ASC) is associated with significant morbidity in paediatric patients with ulcerative colitis (UC). Most outcome studies in ASC since TNF antagonists became available have focused on the first year after admission. The aim of this study was to characterize the longer-term outcomes of paediatric patients admitted with ASC