Application Integration Control System for Multi-Scale and Multi-PhysicsSimulation

In the case of long-period and large-scale simulation, unexpected stop which is caused by execution time excess, outage of computers, outage of a network during file transfer and so on, become major issues. To avoid the stop of job execution and file transfer, we have developed Task Flow Control System that is a new control system for application integration with a fault tolerant API. If the computer is outage, the system designates an alternate computer, gathers necessary files and submits a new job. Each scheduler, file transfer and job condition can be flexibly defined in XML. This time, we applied the system to fluid-structure interaction analysis simulation. The result indicates that the system enables a user to easily execute multi-scale and multi-physics simulation using application integration

Simple Orchestration Application Framework to Control "Burning Plasma Integrated Code"

We have developed the Simple Orchestration Application Framework (SOAF) on a grid infrastructure to control cooperative and multiple execution of simulation codes on remote computers from a client PC. SOAF enables researchers to generate a scenario of their cooperative and multiple executions by only describing a configuration file which includes the information of execution codes and file flows among them. SOAF does not need substantial modification of the simulation codes. We have applied SOAF to the "Burning Plasma Integrated Code" which consists of various plasma simulation codes. In order to predict and interpret the behavior of fusion burning plasma, it is necessary to cooperatively and concurrently execute various simulation codes to understand complex plasma phenomena with wide temporal and spatial ranges. Those codes exist on distributed heterogeneous computers located in different sites such as universities and institutes. By using SOAF, we succeeded to cooperatively and concurrently execute four plasma simulation codes without substantial modification as described in the configuration file

FIP1L1 presence in FIP1L1-RARA or FIP1L1-PDGFRA differentially contributes to the pathogenesis of distinct types of leukemia

FIP1-like 1 (FIP1L1) is associated with two leukemogenic fusion genes: FIP1L1-retinoic acid receptor alpha (RARA) and FIP1L1-platelet-derived growth factor receptor alpha (PDGFRA). Analyses of a series of deletion mutants revealed that the FIP1 motif in FIP1L1-RARA plays a pivotal role in its homodimerization and transcriptional repressor activity. However, in FIP1L1-PDGFRA, the C-terminal PDGFRA portion possesses the ability of forming a homodimer by itself, making FIP1L1 dispensable for constitutive activation of this kinase. Both the full-length and the C-terminal PDGFRA portion of FIP1L1-PDGFRA could transform the IL-3-dependent hematopoietic cell line, BAF-B03. Moreover, when either the full-length or the C-terminal PDGFRA portion of FIP1L1-PDGFRA was introduced in these cells, they grew in the absence of IL-3. The cells having the C-terminal PDGFRA portion of FIP1L1-PDGFRA, however, were partially IL-3 dependent, whereas the cells having the full-length FIP1L1-PDGFRA became completely IL-3 independent for their growth. Taken together, these results show that FIP1L1 differentially contributes to the pathogenesis of distinct types of leukemia

Toward an international sparse linear algebra expert system by interconnecting the ITBL computational Grid with the Grid-TLSE platform

International audienceIn the present paper, the methodology of interoperability between ITBL and Grid-TLSE is described. Grid-TLSE is an expert web site to provides user assistance in choosing the right solver for its problems and appropriate values for the control parameters of the selected solve. The time to solution of linear equation solver strongly depends on the type of problem, the selected algorithm, its implementation and the target computer architecture. Grid-TLSE uses the Diet middleware to distribute computing tasks over the Grid. Therefore, extending the variety of computer architecture by Grid middleware interoperability between Diet and ITBL has a beneficial impact to the expert system. To show the feasibility of the methodology, job transfering program as a special service of Diet was developed

Formation of CuO on TiO₂ Surface Using its Photocatalytic Activity

Some co-catalyst nanoparticles can enhance the activity of photocatalysts due to prolonging the charge separation lifetime by promoting the electron or hole transfer. CuO particles were prepared from an aqueous solution of copper (II) nitrate at 351 K on a TiO2 surface by a photocatalytic reaction and heating at 573 or 673 K. The amount and size of the particles deposited during the photocatalytic reaction can be controlled by changing the amount of the irradiated photons. The CuO crystals with about 50−250 nm-sized particles were formed. Nitrate ions were reduced to nitrite ions in the solution by the photocatalytic activity of the TiO2, and water was simultaneously transformed into hydroxide ions. An increase in the basicity on the TiO2 surface induced formation of a copper hydroxide. The copper hydroxide was subsequently dehydrated and transformed into CuO by heating. The TiO2 loading of a small amount of CuO demonstrated a higher photocatalytic activity for methylene blue degradation compared to the original TiO2 due to the electron transfer from the TiO2 conduction bands to the CuO conduction band