Collisionless Relaxation in Galactic Dynamics and the Evolution of Long Range Order

This talk provides a critical assessment of collisionless galactic dynamics, focusing on the interpretation and limitations of the collisionless Boltzmann equation and the physical mechanisms associated with collisionless relaxation. Numerical and theoretical arguments are presented to motivate the idea that the evolution of a system far from equilibrium should be interpreted as involving nonlinear gravitational Landau damping, which implies a greater overall coherence and remembrance of initial conditions than is implicit in the conventional theory of violent relaxation.Comment: 20 pages, plain latex, no macros required, no figures a talk presented at the 1997 Florida Workshop on Nonlinear Astronomy and Physics, to appear in Annals of the New York Academy of Science

Signatures of Classical Diffusion in Quantum Fluctuations of 2D Chaotic Systems

We consider a two-dimensional (2D) generalization of the standard kicked-rotor (KR) and show that it is an excellent model for the study of 2D quantum systems with underlying diffusive classical dynamics. First we analyze the distribution of wavefunction intensities and compare them with the predictions derived in the framework of diffusive {\it disordered} samples. Next, we turn the closed system into an open one by constructing a scattering matrix. The distribution of the resonance widths ${\cal P}(\Gamma)$ and Wigner delay times ${\cal P}(\tau_W)$ are investigated. The forms of these distributions are obtained for different symmetry classes and the traces of classical diffusive dynamics are identified. Our theoretical arguments are supported by extensive numerical calculations.Comment: 20 pages; 12 figure

Fungal Planet description sheets: 1284–1382

Novel species of fungi described in this study include those from various countries as follows: Antartica, Cladosporium austrolitorale from coastal sea sand. Australia, Austroboletus yourkae on soil, Crepidotus innuopurpureus on dead wood, Curvularia stenotaphri from roots and leaves of Stenotaphrum secundatum and Thecaphora stajsicii from capsules of Oxalis radicosa. Belgium, Paraxerochrysium coryli (incl. Paraxerochrysium gen. nov.) from Corylus avellana. Brazil, Calvatia nordestina on soil, Didymella tabebuiicola from leaf spots on Tabebuia aurea, Fusarium subflagellisporum from hypertrophied floral and vegetative branches of Mangifera indica and Microdochium maculosum from living leaves of Digitaria insularis. Canada, Cuphophyllus bondii fromagrassland. Croatia, Mollisia inferiseptata from a rotten Laurus nobilis trunk. Cyprus, Amanita exilis oncalcareoussoil. Czech Republic, Cytospora hippophaicola from wood of symptomatic Vaccinium corymbosum. Denmark, Lasiosphaeria deviata on pieces of wood and herbaceousdebris. Dominican Republic, Calocybella goethei among grass on a lawn. France (Corsica) , Inocybe corsica onwetground. France (French Guiana) , Trechispora patawaensis on decayed branch of unknown angiosperm tree and Trechispora subregularis on decayed log of unknown angiosperm tree. Germany, Paramicrothecium sambuci (incl. Paramicrothecium gen. nov.)ondeadstemsof Sambucus nigra. India, Aureobasidium microtermitis from the gut of a Microtermes sp. termite, Laccaria diospyricola on soil and Phylloporia tamilnadensis on branches of Catunaregam spinosa. Iran, Pythium serotinoosporum from soil under Prunus dulcis. Italy, Pluteus brunneovenosus on twigs of broad leaved trees on the ground. Japan, Heterophoma rehmanniae on leaves of Rehmannia glutinosa f. hueichingensis. Kazakhstan, Murispora kazachstanica from healthy roots of Triticum aestivum. Namibia, Caespitomonium euphorbiae (incl. Caespitomonium gen. nov.)from stems of an Euphorbia sp. Netherlands, Alfaria junci, Myrmecridium junci, Myrmecridium juncicola, Myrmecridium juncigenum, Ophioceras junci, Paradinemasporium junci (incl. Paradinemasporium gen. nov.), Phialoseptomonium junci, Sporidesmiella juncicola, Xenopyricularia junci and Zaanenomyces quadripartis (incl. Zaanenomyces gen. nov.), fromdeadculmsof Juncus effusus, Cylindromonium everniae and Rhodoveronaea everniae from Evernia prunastri, Cyphellophora sambuci and Myrmecridium sambuci from Sambucus nigra, Kiflimonium junci, Saro cladium junci, Zaanenomyces moderatricis academiae and Zaanenomyces versatilis from dead culms of Juncus inflexus, Microcera physciae from Physcia tenella, Myrmecridium dactylidis from dead culms of Dactylis glomerata, Neochalara spiraeae and Sporidesmium spiraeae from leaves of Spiraea japonica, Neofabraea salicina from Salix sp., Paradissoconium narthecii (incl. Paradissoconium gen. nov.)from dead leaves of Narthecium ossifragum, Polyscytalum vaccinii from Vaccinium myrtillus, Pseudosoloacrosporiella cryptomeriae (incl. Pseudosoloacrosporiella gen. nov.)fromleavesof Cryptomeria japonica, Ramularia pararhabdospora from Plantago lanceolata, Sporidesmiella pini from needles of Pinus sylvestris and Xenoacrodontium juglandis (incl. Xenoacrodontium gen. nov. and Xenoacrodontiaceae fam. nov.)from Juglans regia. New Zealand, Cryptometrion metrosideri from twigs of Metrosideros sp., Coccomyces pycnophyllocladi from dead leaves of Phyllocladus alpinus, Hypoderma aliforme from fallen leaves Fuscopora solandri and Hypoderma subiculatum from dead leaves Phormium tenax. Norway, Neodevriesia kalakoutskii from permafrost and Variabilispora viridis from driftwood of Picea abies. Portugal, Entomortierella hereditatis from abio film covering adeteriorated limestone wall. Russia, Colpoma junipericola from needles of Juniperus sabina, Entoloma cinnamomeum on soil in grasslands, Entoloma verae on soil in grasslands, Hyphodermella pallidostraminea on a dry dead branch of Actinidia sp., Lepiota sayanensis onlitterinamixedforest, Papiliotrema horticola from Malus communis , Paramacroventuria ribis (incl. Paramacroventuria gen. nov.)fromleaves of Ribes aureum and Paramyrothecium lathyri from leaves of Lathyrus tuberosus. South Africa, Harzia combreti from leaf litter of Combretum collinum ssp. sulvense, Penicillium xyleborini from Xyleborinus saxesenii , Phaeoisaria dalbergiae from bark of Dalbergia armata, Protocreopsis euphorbiae from leaf litter of Euphorbia ingens and Roigiella syzygii from twigs of Syzygium chordatum. Spain, Genea zamorana on sandy soil, Gymnopus nigrescens on Scleropodium touretii, Hesperomyces parexochomi on Parexochomus quadriplagiatus, Paraphoma variabilis from dung, Phaeococcomyces kinklidomatophilus from a blackened metal railing of an industrial warehouse and Tuber suaveolens in soil under Quercus faginea. Svalbard and Jan Mayen, Inocybe nivea associated with Salix polaris. Thailand, Biscogniauxia whalleyi oncorticatedwood. UK, Parasitella quercicola from Quercus robur. USA , Aspergillus arizonicus from indoor air in a hospital, Caeliomyces tampanus (incl. Caeliomyces gen. nov.)fromoffice dust, Cippumomyces mortalis (incl. Cippumomyces gen. nov.)fromatombstone, Cylindrium desperesense from air in a store, Tetracoccosporium pseudoaerium from air sample in house, Toxicocladosporium glendoranum from air in a brick room, Toxicocladosporium losalamitosense from air in a classroom, Valsonectria portsmouthensis from airinmen'slockerroomand Varicosporellopsis americana from sludge in a water reservoir. Vietnam, Entoloma kovalenkoi on rotten wood, Fusarium chuoi inside seed of Musa itinerans , Micropsalliota albofelina on soil in tropical evergreen mixed forest sand Phytophthora docyniae from soil and roots of Docynia indica. Morphological and culture characteristics are supported by DNA barcodes

Downregulation of phospho-tyrosine phosphatases in a macrophage tumor

AbstractWe provide evidence for the downregulation of phospho-tyrosine phosphatases (PTPases) in malignancy. AK-5, a rat macrophage tumor, shows the downregulation of the transcripts of two non-receptor-type PTPases, PTP-1 and PTP-S. Though downregulated fourfold, the genomic organization of PTP-S is unaltered. There is no gross alteration of the PTPase activity in AK-5 as compared to macrophages. Immunoblot analysis reveals no significant change in the total phospho-tyrosine levels in AK-5, but there is a qualitative difference in the pattern between AK-5 and macrophages. Our results lend credence to the conjecture that PTPases also might be involved in malignancy

Data on alteration of hormone and growth factor receptor profiles over progressive passages of breast cancer cell lines representing different clinical subtypes

Human breast cancers are a highly heterogeneous group of tumours consisting of several molecular subtypes with a variable profile of hormone, growth factor receptors and cytokeratins [1]. Here, the data shows immunofluorescence profiling of four different cell lines belonging to distinct clinical subtypes of breast cancer. Post revival, the cell lines were passaged in culture and immunophenotyping was done for ER, HER-2, AR and EGFR. Data for the markers from early passage (5th) through passages as late as 25 for the different cell lines is presented. Keywords: Breast cancer, Cell lines, Immunofluorescenc

A Phase I study of 4'-O-tetrahydropyranyladriamycin: clinical pharmacology and pharmacokinetics

Pirarubicin is a synthetic analogue of doxorubicin (Adriamycin). The substance shows promise as a new anticancer agent. Fewer cell lines appear to be resistance to pirarubicin compared with doxorubicin. Furthermore, the side effects of pirarubicin seem to be no greater than that of doxorubicin. Toxicity to the heart is the most serious side effect of doxorubicin, and this particular side effect seems to be less serious with pirarubicin. As a part of a Phase I study of pirarubicin in treating cancer, researchers evaluated the uptake and metabolism of pirarubicin to determine the optimal dose range for use in further tests of the drug. The investigators found that the dose-limiting side effect of pirarubicin was a reduction in granulocytes in the blood, which may be life-threatening with higher doses of the drug. Monitoring of heart function showed a dose-dependent decrease in the left-ventricular ejection fraction, which suggests that the drug may be different from its parent doxorubicin. The cardiotoxicity of doxorubicin does not appear to be dose dependent, but is abrupt after the cumulative dose crosses a threshold. Unfortunately, the present study was not large enough to fully compare the cardiotoxicity of the two drugs. Pirarubicin disappears from the blood significantly more rapidly than doxorubicin, which may result from increased uptake of the compound by tumor cells and blood cells. The analysis of the metabolites of pirarubicin revealed that doxorubicin constitutes less than 10 percent of the various metabolites, which suggests that pirarubicin is an independent anticancer agent and is not merely degraded into doxorubicin in the body. Both drugs seem to work by a similar mechanism, however; pirarubicin and doxorubicin interfere with cellular replication by inducing breaks in DNA strands. (Consumer Summary produced by Reliance Medical Information, Inc.)Professiona