Global surveillance of cancer survival 1995-2009: analysis of individual data for 25,676,887 patients from 279 population-based registries in 67 countries (CONCORD-2)

BACKGROUND: Worldwide data for cancer survival are scarce. We aimed to initiate worldwide surveillance of cancer survival by central analysis of population-based registry data, as a metric of the effectiveness of health systems, and to inform global policy on cancer control. METHODS: Individual tumour records were submitted by 279 population-based cancer registries in 67 countries for 25·7 million adults (age 15-99 years) and 75,000 children (age 0-14 years) diagnosed with cancer during 1995-2009 and followed up to Dec 31, 2009, or later. We looked at cancers of the stomach, colon, rectum, liver, lung, breast (women), cervix, ovary, and prostate in adults, and adult and childhood leukaemia. Standardised quality control procedures were applied; errors were corrected by the registry concerned. We estimated 5-year net survival, adjusted for background mortality in every country or region by age (single year), sex, and calendar year, and by race or ethnic origin in some countries. Estimates were age-standardised with the International Cancer Survival Standard weights. FINDINGS: 5-year survival from colon, rectal, and breast cancers has increased steadily in most developed countries. For patients diagnosed during 2005-09, survival for colon and rectal cancer reached 60% or more in 22 countries around the world; for breast cancer, 5-year survival rose to 85% or higher in 17 countries worldwide. Liver and lung cancer remain lethal in all nations: for both cancers, 5-year survival is below 20% everywhere in Europe, in the range 15-19% in North America, and as low as 7-9% in Mongolia and Thailand. Striking rises in 5-year survival from prostate cancer have occurred in many countries: survival rose by 10-20% between 1995-99 and 2005-09 in 22 countries in South America, Asia, and Europe, but survival still varies widely around the world, from less than 60% in Bulgaria and Thailand to 95% or more in Brazil, Puerto Rico, and the USA. For cervical cancer, national estimates of 5-year survival range from less than 50% to more than 70%; regional variations are much wider, and improvements between 1995-99 and 2005-09 have generally been slight. For women diagnosed with ovarian cancer in 2005-09, 5-year survival was 40% or higher only in Ecuador, the USA, and 17 countries in Asia and Europe. 5-year survival for stomach cancer in 2005-09 was high (54-58%) in Japan and South Korea, compared with less than 40% in other countries. By contrast, 5-year survival from adult leukaemia in Japan and South Korea (18-23%) is lower than in most other countries. 5-year survival from childhood acute lymphoblastic leukaemia is less than 60% in several countries, but as high as 90% in Canada and four European countries, which suggests major deficiencies in the management of a largely curable disease. INTERPRETATION: International comparison of survival trends reveals very wide differences that are likely to be attributable to differences in access to early diagnosis and optimum treatment. Continuous worldwide surveillance of cancer survival should become an indispensable source of information for cancer patients and researchers and a stimulus for politicians to improve health policy and health-care systems

Phase Behavior of Aqueous Na-K-Mg-Ca-CI-NO3 Mixtures: Isopiestic Measurements and Thermodynamic Modeling

A comprehensive model has been established for calculating thermodynamic properties of multicomponent aqueous systems containing the Na{sup +}, K{sup +}, Mg{sup 2+}, Ca{sup 2+}, Cl{sup -}, and NO{sub 3}{sup -} ions. The thermodynamic framework is based on a previously developed model for mixed-solvent electrolyte solutions. The framework has been designed to reproduce the properties of salt solutions at temperatures ranging from the freezing point to 300 C and concentrations ranging from infinite dilution to the fused salt limit. The model has been parameterized using a combination of an extensive literature database and new isopiestic measurements for thirteen salt mixtures at 140 C. The measurements have been performed using Oak Ridge National Laboratory's (ORNL) previously designed gravimetric isopiestic apparatus, which makes it possible to detect solid phase precipitation. Water activities are reported for mixtures with a fixed ratio of salts as a function of the total apparent salt mole fraction. The isopiestic measurements reported here simultaneously reflect two fundamental properties of the system, i.e., the activity of water as a function of solution concentration and the occurrence of solid-liquid transitions. The thermodynamic model accurately reproduces the new isopiestic data as well as literature data for binary, ternary and higher-order subsystems. Because of its high accuracy in calculating vapor-liquid and solid-liquid equilibria, the model is suitable for studying deliquescence behavior of multicomponent salt systems

Polyelectrolytes-promoted forward osmosis processes

10.1016/j.proeng.2012.08.378Procedia Engineering44256-25

A review of the mathematical models for predicting rotary desiccant wheel

In the solid desiccant wheel air-conditioning system, the performance of the desiccant wheel is critical to the capability, size and cost of the whole system. Constructing mathematical model is an effective method for analyzing the performance of the rotary wheel as well as the system. The model can also be used to guide system operation, interpret experimental results and assist in system design and optimization. The overall objective of this paper is to provide a review of various efforts that researchers have made to mathematically model the coupled heat and mass transfer process occurring within the wheel. The paper first briefly describes desiccant wheel including fundamental principle, heat and mass transfer mechanism and the method of model establishment. Then various models consisting of ideal assumptions, governing equations, auxiliary conditions, solution methods and main results are presented. The models can be classified into two main categories: (1) gas-side resistance (GSR) model; (2) gas and solid-side resistance (GSSR) model which can be further subdivided into pseudo-gas-side (PGS) model, gas and solid-side (GSS) model and parabolic concentration profile (PCP) model. It shows that GSSR models are higher in precision and more complex compared with GSR models. In addition, the simplified empirical models based on measured data are briefly discussed. This review is useful for understanding the evolution process and status quo of the mathematical model and highlighting the key aspects of model improvement such as taking account of pressure loss or air leakage.Desiccant wheel Mathematical model

How the Brunswikian Lens Model Illustrates the Relationship Between Physiological and Behavioral Signals and Psychological Emotional and Cognitive States

Social relationships are constructed by and through the relational communication that people exchange. Relational messages are implicit nonverbal and verbal messages that signal how people regard one another and define their interpersonal relationships—equal or unequal, affectionate or hostile, inclusive or exclusive, similar or dissimilar, and so forth. Such signals can be measured automatically by the latest machine learning software tools and combined into meaningful factors that represent the socioemotional expressions that constitute relational messages between people. Relational messages operate continuously on a parallel track with verbal communication, implicitly telling interactants the current state of their relationship and how to interpret the verbal messages being exchanged. We report an investigation that explored how group members signal these implicit messages through multimodal behaviors measured by sensor data and linked to the socioemotional cognitions interpreted as relational messages. By use of a modified Brunswikian lens model, we predicted perceived relational messages of dominance, affection, involvement, composure, similarity and trust from automatically measured kinesic, vocalic and linguistic indicators. The relational messages in turn predicted the veracity of group members. The Brunswikian Lens Model offers a way to connect objective behaviors exhibited by social actors to the emotions and cognitions being perceived by other interactants and linking those perceptions to social outcomes. This method can be used to ascertain what behaviors and/or perceptions are associated with judgments of an actor’s veracity. Computerized measurements of behaviors and perceptions can replace manual measurements, significantly expediting analysis and drilling down to micro-level measurement in a previously unavailable manner. Copyright © 2022 Burgoon, Wang, Chen, Ge and Dorn.Open access journalThis item from the UA Faculty Publications collection is made available by the University of Arizona with support from the University of Arizona Libraries. If you have questions, please contact us at [email protected]

ON THE MECHANISM OF THE LOW TEMPERATURE INTERNAL FRICTION PEAKS IN COLD-WORKED Al - 0,5 wt% Cu AND Al - 4 wt% Cu ALLOYS

A detailed analysis of the low-frequency internal-friction peak observed in cold-worked Al-0.5 wt% (0.21 at%) Cu around 214 K (f= 2Hz) showed that it consists of two closely-situated internal-friction peaks : a relaxation peak (R-peak) and a "phase transformation peak" (P-peak). A.model of dragging by dislocations is suggested for the R-peak in which the copper atom-vacancy pairs are the mobile pinning agents. Experiments on Al-4 wt% (1.6 at%) Cu showed that the frequency-independent P-peak observed around 224 K cannot be attributed to the presence of G.P. [1] zone. This peak may be associated with some clustering stage of the Cu atoms in aluminum just before the formation of the G.P.[1] zone and may be correlated to an ordering phenomenon

Genetic algorithm combined with finite element method for robust design of actuators

10.1109/20.877639IEEE Transactions on Magnetics364 I1128-1131IEMG

Technical development of rotary desiccant dehumidification and air conditioning: A review

Rotary desiccant air conditioning system, which combines the technologies of desiccant dehumidification and evaporative cooling, is advantageous in being free from CFCs, using low grade thermal energy and controlling humidity and temperature separately. Compared with conventional vapor compression air conditioning system, it preserves the merits of environment-friendly, energy saving, healthy, comfortable, etc. Ongoing research and development works suggest that new desiccant materials and novel system configurations have significant potential for improving the performance and reliability and reducing the cost and size of rotary desiccant dehumidification and air conditioning system, thereby increasing its market competitiveness and breaking out the current fairly small niche market. For the purpose of providing an overview of recent efforts on these issues and showing how rotary desiccant air conditioning systems can be designed and coupled to available thermal energy, this paper presents and analyzes the status of rotary desiccant dehumidification and air conditioning in the following three aspects: the development of advanced desiccant materials, the optimization of system configuration and the utilization of solar energy and other low grade heat sources, such as solar energy, district heating, waste heat and bioenergy. Some key problems to further push forward the research and development of this technology are also summarized.Desiccant dehumidification Solar energy Low grade thermal energy Air conditioning