152 research outputs found
De Sitter Gravity and Liouville Theory
We show that the spectrum of conical defects in three-dimensional de Sitter
space is in one-to-one correspondence with the spectrum of vertex operators in
Liouville conformal field theory. The classical conformal dimensions of vertex
operators are equal to the masses of the classical point particles in dS_3 that
cause the conical defect. The quantum dimensions instead are shown to coincide
with the mass of the Kerr-dS_3 solution computed with the Brown-York stress
tensor. Therefore classical de Sitter gravity encodes the quantum properties of
Liouville theory. The equality of the gravitational and the Liouville stress
tensor provides a further check of this correspondence. The Seiberg bound for
vertex operators translates on the bulk side into an upper mass bound for
classical point particles. Bulk solutions with cosmological event horizons
correspond to microscopic Liouville states, whereas those without horizons
correspond to macroscopic (normalizable) states. We also comment on recent
criticism by Dyson, Lindesay and Susskind, and point out that the
contradictions found by these authors may be resolved if the dual CFT is not
able to capture the thermal nature of de Sitter space. Indeed we find that on
the CFT side, de Sitter entropy is merely Liouville momentum, and thus has no
statistical interpretation in this approach.Comment: 22 pages, LateX2e; added references for section 1 and section 2;
corrected typos; improved discussion in section
Quintessential Maldacena-Maoz Cosmologies
Maldacena and Maoz have proposed a new approach to holographic cosmology
based on Euclidean manifolds with disconnected boundaries. This approach
appears, however, to be in conflict with the known geometric results [the
Witten-Yau theorem and its extensions] on spaces with boundaries of
non-negative scalar curvature. We show precisely how the Maldacena-Maoz
approach evades these theorems. We also exhibit Maldacena-Maoz cosmologies with
[cosmologically] more natural matter content, namely quintessence instead of
Yang-Mills fields, thereby demonstrating that these cosmologies do not depend
on a special choice of matter to split the Euclidean boundary. We conclude that
if our Universe is fundamentally anti-de Sitter-like [with the current
acceleration being only temporary], then this may force us to confront the
holography of spaces with a connected bulk but a disconnected boundary.Comment: Much improved exposition, exponent in Cai-Galloway theorem fixed,
axionic interpretation of scalar explained, JHEP version. 33 pages, 3 eps
figure
Pt clusters in BaKL zeolite: Characterization by transmission electron microscopy, hydrogen chemisorption, and X-ray absorption spectroscopy
Anthropogenic Space Weather
Anthropogenic effects on the space environment started in the late 19th
century and reached their peak in the 1960s when high-altitude nuclear
explosions were carried out by the USA and the Soviet Union. These explosions
created artificial radiation belts near Earth that resulted in major damages to
several satellites. Another, unexpected impact of the high-altitude nuclear
tests was the electromagnetic pulse (EMP) that can have devastating effects
over a large geographic area (as large as the continental United States). Other
anthropogenic impacts on the space environment include chemical release ex-
periments, high-frequency wave heating of the ionosphere and the interaction of
VLF waves with the radiation belts. This paper reviews the fundamental physical
process behind these phenomena and discusses the observations of their impacts.Comment: 71 pages, 35 figure
Dwelling on de Sitter
A careful reduction of the three-dimensional gravity to the Liouville
description is performed, where all gauge fixing and on-shell conditions come
from the definition of asymptotic de Sitter spaces. The roles of both past and
future infinities are discussed and the conditions space-time evolution imposes
on both Liouville fields are explicited. Space-times which correspond to
non-equivalent profiles of the Liouville field at past and future infinities
are shown to exist. The qualitative implications of this for any tentative dual
theory are presented.Comment: RevTeX 4, 8 pages, v3: Small clarifications on sections III and IV
and references added/corrected, v4: typo
Rare SLC13A1 variants associate with intervertebral disc disorder highlighting role of sulfate in disc pathology
Publisher Copyright: © 2022, The Author(s).Back pain is a common and debilitating disorder with largely unknown underlying biology. Here we report a genome-wide association study of back pain using diagnoses assigned in clinical practice; dorsalgia (119,100 cases, 909,847 controls) and intervertebral disc disorder (IDD) (58,854 cases, 922,958 controls). We identify 41 variants at 33 loci. The most significant association (ORIDD = 0.92, P = 1.6 × 10−39; ORdorsalgia = 0.92, P = 7.2 × 10−15) is with a 3’UTR variant (rs1871452-T) in CHST3, encoding a sulfotransferase enzyme expressed in intervertebral discs. The largest effects on IDD are conferred by rare (MAF = 0.07 − 0.32%) loss-of-function (LoF) variants in SLC13A1, encoding a sodium-sulfate co-transporter (LoF burden OR = 1.44, P = 3.1 × 10−11); variants that also associate with reduced serum sulfate. Genes implicated by this study are involved in cartilage and bone biology, as well as neurological and inflammatory processes.Peer reviewe
Bovine respiratory syncytial virus: immunohistochemichal detection in mouse and bovine tissues using a Mab against human respiratory syncytial virus
Star clusters near and far; tracing star formation across cosmic time
© 2020 Springer-Verlag. The final publication is available at Springer via https://doi.org/10.1007/s11214-020-00690-x.Star clusters are fundamental units of stellar feedback and unique tracers of their host galactic properties. In this review, we will first focus on their constituents, i.e.\ detailed insight into their stellar populations and their surrounding ionised, warm, neutral, and molecular gas. We, then, move beyond the Local Group to review star cluster populations at various evolutionary stages, and in diverse galactic environmental conditions accessible in the local Universe. At high redshift, where conditions for cluster formation and evolution are more extreme, we are only able to observe the integrated light of a handful of objects that we believe will become globular clusters. We therefore discuss how numerical and analytical methods, informed by the observed properties of cluster populations in the local Universe, are used to develop sophisticated simulations potentially capable of disentangling the genetic map of galaxy formation and assembly that is carried by globular cluster populations.Peer reviewedFinal Accepted Versio
Optimization of self-nanoemulsifying formulations for weakly basic lipophilic drugs: role of acidification and experimental design
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