29 research outputs found
Effect of Melatonin Infusion Duration and Frequency on Gonad, Lipid, and Body Mass in Pinealectomized Male Siberian Hamsters1
White adipose tissue lacks significant vagal innervation and immunohistochemical evidence of parasympathetic innervation.
Interruption of nocturnal pineal melatonin synthesis in spontaneous recrudescent Djungarian hamsters (Phodopus sungorus)
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Transneuronal Circuit Analysis with Pseudorabies Viruses
Our ability to understand the function of the nervous system is dependent upon defining the connections of its constituent neurons. Development of methods to define connections within neural networks has always been a growth industry in the neurosciences. Transneuronal spread of neurotropic viruses currently represents the best means of defining synaptic connections within neural networks. The method exploits the ability of viruses to invade neurons, replicate, and spread through the intimate synaptic connections that enable communication among neurons. Since the method was first introduced in the 1970s, it has benefited from an increased understanding of the virus life cycle, the function of viral genome, and the ability to manipulate the viral genome in support of directional spread of virus and the expression of transgenes. In this unit, we review these advances in viral tracing technology and the way in which they may be applied for functional dissection of neural networks