96 research outputs found

    A New Pairwise Ensemble Approach for Text Classification

    Full text link

    HATS-31B THROUGH HATS-35B: FIVE TRANSITING HOT JUPITERS DISCOVERED by the HATSOUTH SURVEY

    Get PDF
    We report the discovery of five new transiting hot-Jupiter planets discovered by the HATSouth survey, HATS-31b through HATS-35b. These planets orbit moderately bright stars with V magnitudes within the range of 11.911.9–14.414.4 mag while the planets span a range of masses of 0.880.88–1.221.22 MJ{M}_{{\rm{J}}} and have somewhat inflated radii between 1.231.23 and 1.641.64 RJ{R}_{{\rm{J}}}. These planets can be classified as typical hot Jupiters, with HATS-31b and HATS-35b being moderately inflated gas giant planets with radii of 1.64±0.221.64\pm 0.22 RJ{R}_{{\rm{J}}} and 1.464−0.044+0.069{1.464}_{-0.044}^{+0.069} RJ{R}_{{\rm{J}}}, respectively, that can be used to constrain inflation mechanisms. All five systems present a higher Bayesian evidence for a fixed-circular-orbit model than for an eccentric orbit. The orbital periods range from 1.8209993±0.00000161.8209993\pm 0.0000016 day for HATS-35b) to 3.377960±0.0000123.377960\pm 0.000012 day for HATS-31b. Additionally, HATS-35b orbits a relatively young F star with an age of 2.13±0.512.13\pm 0.51 Gyr. We discuss the analysis to derive the properties of these systems and compare them in the context of the sample of well-characterized transiting hot Jupiters known to date

    The use of Brazilian vegetable oils in nanoemulsions: an update on preparation and biological applications

    Get PDF
    ABSTRACT Vegetable oils present important pharmacological properties, which gained ground in the pharmaceutical field. Its encapsulation in nanoemulsions is considered a promising strategy to facilitate the applicability of these natural compounds and to potentiate the actions. These formulations offer several advantages for topical and systemic delivery of cosmetic and pharmaceutical agents including controlled droplet size, protection of the vegetable oil to photo, thermal and volatilization instability and ability to dissolve and stabilize lipophilic drugs. For these reasons, the aim of this review is to report on some characteristics, preparation methods, applications and especially analyze recent research available in the literature concerning the use of vegetable oils with therapeutic characteristics as lipid core in nanoemulsions, specially from Brazilian flora, such as babassu (Orbignya oleifera), aroeira (Schinus molle L.), andiroba (Carapa guaianiensis), casca-de-anta (Drimys brasiliensis Miers), sucupira (Pterodon emarginatus Vogel) and carqueja doce (Stenachaenium megapotamicum) oils

    Evaluating the Effects of SARS-CoV-2 Spike Mutation D614G on Transmissibility and Pathogenicity

    Get PDF
    Global dispersal and increasing frequency of the SARS-CoV-2 spike protein variant D614G are suggestive of a selective advantage but may also be due to a random founder effect. We investigate the hypothesis for positive selection of spike D614G in the United Kingdom using more than 25,000 whole genome SARS-CoV-2 sequences. Despite the availability of a large dataset, well represented by both spike 614 variants, not all approaches showed a conclusive signal of positive selection. Population genetic analysis indicates that 614G increases in frequency relative to 614D in a manner consistent with a selective advantage. We do not find any indication that patients infected with the spike 614G variant have higher COVID-19 mortality or clinical severity, but 614G is associated with higher viral load and younger age of patients. Significant differences in growth and size of 614G phylogenetic clusters indicate a need for continued study of this variant
    • 

    corecore