EFFECT OF PRIORITY DRINKING WATER CONTAMINANTS ON THE QUALITY INDICATORS OF BEVERAGES DURING THEIR PRODUCTION AND STORAGE

Currently, water from the centralized domestic drinking water supply system is mainly used to make non- alcoholic carbonated beverages and nectars. The classical technology does not always provide the purification of water from organic compounds. In addition, during water preparation, at the primary chlorination stage, chlorine-containing organic compounds (chloroform, dichloroethane, trichlorethylene, etc.) are formed due to the interaction of chlorine with natural organic substances. The by-products of natural water treatment by chloragents, in addition to the toxic and carcinogenic effects, can interact with the main components of products reducing their quality. Such water cannot be used for drinking purposes and in food production without the additional post-treatment. The results of the study of the effect of organic impurities present in water (chloroform, trichlorethylene and dichloroethane) on the stability of the components of non-alcoholic carbonated beverages (sodium benzoate, sucrose, citric acid, natural and synthetic dyes and vanillin) and nectars (color stability, vitamins A, C, group B) have been provided. The studies were carried out in the Kemerovo region using gas-liquid chromatography, molecular absorption spectroscopy, refractometry and capillary electrophoresis. The concentration of the main components of non-alcoholic carbonated beverages, nectars and priority contaminants (trichlorethylene and dichloroethane) has been reduced. It has been shown that chloroform does not come into chemical interaction with the components of beverages. The mechanism of interaction of sucrose, citric acid, sodium benzoate, vanillin, vitamins in non-alcoholic carbonated beverages and nectars with trichlorethylene and dichloroethane has been theoretically justified. It has been established that dichloroethane and trichlorethylene have a significant effect on the resistance of the main components of non-alcoholic carbonated beverages, with the exception of dyes, and also on the intensity of color and the preservation of vitamins of nectars, reducing the quality characteristics of beverages during production and storage

Клинический случай синдрома Блоха — Сульцбергера

Purpose.To present a clinical case of Bloch Sulzberger syndrome. Material and methods. The examinations were performed to diagnose the disease: а visual examination of the skin, cytological analysis of the gallbladder fluid, general and biochemical blood tests, genetic research. Results.During a visual examination of the skin, a differential diagnosis was made with infectious dermatitis, toxic-allergic dermatitis, epidermolysis bullosa and linear IgA-dependent dermatosis in children. Crucial in the diagnosis belonged to a genetic study, after which a deletion of exons 410 of the IKBKG gene was detected, which confirmed Bloch Sulzberger syndrome. Conclusion.Newborns with vesicle-bullous rashes entering the neonatal pathology department and observed by neonatologists require a thorough examination, a mandatory consultation of a dermatologist inorder to determine further management tactics.Цель.Представить клинический случай синдрома БлохаСульцбергера. Материал и методы.Для диагностики заболевания были проведены осмотр кожи, цитологический анализ пузырной жидкости, общий и биохимический анализы крови, генетическое исследование. Результаты.При осмотре кожи был проведен дифференциальный диагноз с дерматитами, буллезным эпидермолизом и линеарным IgA-зависимым дерматозом у детей. Решающее значение в постановке диагноза принадлежало генетическому исследованию, после проведения которого была выявлена делеция экзонов 410 гена IKBKG, что подтвердило синдром БлохаСульцбергера. Заключение.Новорожденные с везикуло-буллезными высыпаниями, поступающие в отделение патологии новорожденных и наблюдаемые неонатологами, требуют тщательного обследования, обязательной консультации дерматолога с целью определения дальнейшей тактики ведения

BEER QUALITY ASSURANCE BY CONTROLLING WORT POLYPHENOLIC CONTENT WITH ADSORPTION METHOD

This research explores feasibility of adsorption method used for regulating polypenols content in wort with a view of improving beer quality. It examines adsorption of polyphenols (quercetin, gallic acid, rutin) from pure substance solutions, their mixtures and beer wort treated by sorbents that differ by origin, making, structure and surface chemical composition. The work determines patterns and specific features of polyphenols adsorption with activated carbons. To describe adsorption mechanism more precisely, we specified structure, surface chemical condition, and calculated adsorption parameters using equations of Langmuir, Freundlich and Dubinin-Radushkevich, and the multilayer adsorption theory (BET model). It is demonstrated that polyphenols adsorption mechanism depends on carbon characteristics and is of physical nature that reveals itself in dispersion interaction in micropores and in specific one with oxygen-containing functional group (OFG) on carbon surface. Polyphenol competitive adsorption in mixture and wort recognized. At polyphenols adsorption from model solutions and wort, carbon sorbents are identified to share sufficiently close sorption characteristics. We performed comparative evaluation of quality characteristics of beer produced from activated carbons treated and untreated worts. It is shown that beer samples produced from unhopped wort filtered through semi-coke adsorption, meet regulatory standards requirements of safety by organoleptic, physical and chemical indicators. Moreover, beer obtained from semi-coke treated wort exceeds control sample in terms of organoleptic and stability ensuring indicators

THE CHOICE OF SORBENT FOR ADSORPTION EXTRACTION OF CHLOROFORM FROM DRINKING WATER

At present, providing the population with clean drinking water is one of the most important urgent problems of our time. Due to seasonal changes in water composition and violation of water treatment technology, the conventional process is not always effective to ensure water purification of organic compounds. Moreover, more hazardous contaminants may form unlike the previous ones. Humic substances act as the main source of chloroform formation for water decontamination during the water treatment. Adsorption chloroform extraction from water was studied under static conditions using KAU, SKD-515, BAU, AG-3, AG-OV-1 carbon, ABG semi-coke, PFS polymer sorbents and Porolas T and active nonwoven fabric that differ in the production method, structure and specific surface. Main regularities, features and mechanism for adsorption extraction of chloroform from water are identified for test sorbents. The Freundlich and Langmuir equations (theories of monomolecular adsorption), the Dubinin-Radushkevich equation, modified for adsorption from aquatic solution (theory of micro-pore bulk filling) and the BET equation (generalized theory of polymolecular adsorption of Brunauer, Emmett, and Teller) are used to define sorbents and calculate adsorption parameters. To study the potential to increase the sorbent adsorption capacity due variations in the surface structure and chemistry, sorbents were modified by hydrochloric acid solutions and sodium hydroxide. In absence of experimental studies, the technique is developed to define the limiting value of organic compound adsorption not interacting with surface functional groups of carbon sorbents with the developed system of micropores. The sorbent with the best adsorption properties regarding chloroform was recommended

Reliable online social network data collection

Large quantities of information are shared through online social networks, making them attractive sources of data for social network research. When studying the usage of online social networks, these data may not describe properly users’ behaviours. For instance, the data collected often include content shared by the users only, or content accessible to the researchers, hence obfuscating a large amount of data that would help understanding users’ behaviours and privacy concerns. Moreover, the data collection methods employed in experiments may also have an effect on data reliability when participants self-report inacurrate information or are observed while using a simulated application. Understanding the effects of these collection methods on data reliability is paramount for the study of social networks; for understanding user behaviour; for designing socially-aware applications and services; and for mining data collected from such social networks and applications. This chapter reviews previous research which has looked at social network data collection and user behaviour in these networks. We highlight shortcomings in the methods used in these studies, and introduce our own methodology and user study based on the Experience Sampling Method; we claim our methodology leads to the collection of more reliable data by capturing both those data which are shared and not shared. We conclude with suggestions for collecting and mining data from online social networks.Postprin

β-endorphin-like peptide SLTCLVKGFY is a selective agonist of nonopioid β-endorphin receptor

It has been found that β-endorphin (β-END) and a synthetic β-END-like decapeptide Ser-Leu-Thr-Cys-Leu-Val-Lys-Gly-Phe-Tyr (termed immunorphin, IMN) corresponding to the sequence 364-373 of human IgG heavy chain stimulate Con A-induced proliferation of T lymphocytes from the blood of healthy donors. [Met5]enkephalin ([Met5]ENK) and an antagonist of opioid receptors naloxone (NAL) tested in parallel were not active. The stimulating effect of β-END and IMN on T lymphocyte proliferation was not inhibited by NAL. Studies on receptor binding of 125I-labeled IMN to T lymphocytes revealed that it binds with high affinity to NAL-insensitive binding sites (Kd = 7.0 ± 0.3 nM). Unlabeled β-END completely inhibited the specific binding of 125I-labeled IMN to NAL-insensitive binding sites on T lymphocytes (Ki = 1.1 ± 0.2 nM). Thus, β-END and IMN bind to common NAL-insensitive binding sites on T lymphocytes and enhance Con A-induced proliferation of these cells. © 2002 Elsevier Science (USA)