55 research outputs found

    Effects of methyl prednisolone, dimethyl sulphoxide and naloxone in experimental spinal cord injuries in rats

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    PubMed ID: 2907111The effects of methyl prednisolone (MPD), dimethyl sulphoxide (DMSO), and naloxone were examined in 38 albino rats after making an impact spinal cord injury on the midthoracic segments with a modified Allen's weight dropping trauma method. Somatosensorial evoked potentials (SEPs) were recorded before and 12 h and 14 d after the injury from epidurally inserted electrodes on the parietal cortex with sciatic nerve stimulations. Lower extremity motor functions of the animals were also examined. It may be concluded that in this study model, DMSO has a moderate effect which can be demonstrated clinically and through SEPs. Naloxone has no effect on the clinical outcome but causes reasonable improvement electrophysiologically

    The Effects of Propofol and Nitrous-Oxide on Median Nerve Somatosensory-Evoked Potentials During Fentanyl Anesthesia

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    5th International Symposium on Spinal Cord Monitoring -- JUN 02-05, 1992 -- LONDON, ENGLANDWOS: A1994BZ86Q00033BRIT SCOLIOSIS RES FDN, BRIT ORTHOPAED ASSOC, SCOLIOSIS RES TRUST ARIS

    EVALUATION OF CATECHOL AMINE LEVELS IN RENAL INSUFFICIENCY

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    The estimation of epinephrine (E) and norepi-nephrine (NE) in plasma and urine has become important as a procedure in physiological research and as an aid in the diagnosis of pheochromocy-toma. With the development of fluorometric pro-cedures the chemical estimation of E and NE in biological fluids and tissues was made possible. The fluorometric procedures used most com-monly are modifications of the trihydroxyindole method of Lund (1) and the ethylenediamine (EDA) condensation method of Weil-Malherbe and Bone (2, 3). The trihydroxyindole method is not sensitive enough to permit measurements of E and NE in small amounts of normal periph-eral plasma (1), and its practical usefulness is lim
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