ORGANIZING OF SANITARY-AND-QUARANTINE CONTROL IN PASSING POINT «BLAGOVESHSCENSK»

Blagoveshchensk City has the border with PRC along the Amur River and has principal international contacts with this country, where epidemic situation for «atypical pneumonia» became complicated and threat of this infection delivery to the Amur region arose. All the year round transportations are held through the passing point «Blagoveshchensk» by water during navigation period and by iceroad in winter. Technological plans for passing people, loads and transport over the border are prepared taking into account this regime. Formed situation concerning SARS in SouthEastern Asia countries needed additional antiepidemic and preventive measures. The control after passengers was increased, medical examination was held with obligatory thermometry of all people from abroad. Individuals with fever were not admitted to pass the border, and Russian tourists were placed to insulator. The system of monitoring of RF citizen departure to central and southern China provinces is developed and introduced. The resources of individual protection were restocked, desinfection regime was brought in, medical insulator was managed. The cooperation of all control services was regulated. Rational principles of sanitaryandquarantine control organizing in the passing point allowed to prevent the delivery and spreading of SARS on the territory of RF

Analysis of Social Wellbeing Parameters in Russia

This article is devoted to dynamics of the social wellbeing index counted for Siberian region in context of the modernization processes in Russia. The study is based on representative samples from population surveys conducted in 2011 and 2015. It is complemented by the Russian region's modernization map, which was prepared within the data calculated under the procedure developed by Modernization Research Center of China Academy (adapted for Russia). It has been found that the social wellbeing of the population has not significantly changed over the last 5 years despite the current crisis. Also regions are unbalanced in terms of modernization processes, most of them don't even reach the level of capital cities in terms of modernization parameters and social welfare. Tomsk region is a remote Siberian region, but it has the specific "innovative" status and it shows better wellbeing indicators than Russia as a whole. The study was conducted under the RFH sponsorship as project №15-03-00366 "Social and cultural factors of the new modernization in the regions (on research in the Tomsk region)"

Population Notification Concerning Sanitary-Epidemiological Situation and Current Sanitary Anti-Epidemic Operations (Prophylactic Measures) in the Period of Flood in the Amur Region

Displayed are the results of work of the Rospotrebnadzor Administration in the Amur Region in view of the population notification concerning sanitary-epidemiological situation and current anti-epidemic operations under the emergency event preconditioned by the large-scale high water, 2013. In order to avoid aggravation of epidemiological situation in the region, Rospotrebnadzor Administration has performed provision of the exposed population in the devastated territories (including temporal accommodation sites) with the information on the significance of adherence to personal safety practices for infectious diseases prevention, of usage high quality drinking water only (boiled or bottled and distilled), of immunization against viral hepatitis A, typhoid fever and Sonne dysentery, of sanitation activities in the lodgings, back yards, wells, as well as of holding to the discipline of rodent-born infection prevention. On-time notification of the population under emergency conditions benefited to the reduction of risks associated with aggravation of sanitary-epidemiological situation in the exposed territories

Application of the Rapid Linear Immune-Electrophoresis for Differentiation between Burkholderia

Objective of the study was to develop a method that would allow for rapid linear immune-electrophoresis to differentiate between pathogenic agents of glanders and melioidosis and non-pathogenic closely-related Burkholderia . The put-forward modification of the technique made it possible to detect the antigens of pathogenic B. pseudomallei and B. mallei due to the presence of precipitation lines in between the sample gel and the one with immune sera. B. thailandensis, B. cepacia, and B. gladioli did not form such precipitation lines, which in its turn provided for the possibility to differentiate between the mentioned ones and pathogenic Burkholderia. The rapid enhanced linear immune-electrophoresis is easy to perform and compelling, and takes little time. It is qualified for identification of heterogenic and specific antigens in Burkholderia , selection of immune sera containing antibodies to the existing antigens, and can be used as a supportive alternative analytical means for the detection of antigens of pathogenic Burkholderia

Comparative Analysis of Immunochemical Methods Applied for Studies of Pathogenic Burkholderia Antigens

Studied are immunochemical properties of antigen preparations, the spectrum and molar masses of the components contained. Demonstrated is the significance of vertical SDS-polyacrylamide gel electrophoresis, immunodiffusion test, immunoelectrophoresis assay, rocket immunoelectrophoresis with specific sera for identification and differentiation of Burkholderia. Rocket immunoelectrophoresis should be viewed as the most informative method which allows for differentiation between pathogenic and non-pathogenic for humans Burkholderia under usual terms

Obtainment of Monoclonal Antibodies and Prospects of Their Application as Basis for Immunodiagnostic Aids for Crimean-Congo Hemorrhagic Fever Virus Detection

) as framework for the production of tools for CCHF virus detection and identification in artificially contaminated samples and clinical specimens containing CCHF antigens was proven efficient

СОПУТСТВУЮЩИЕ ЗАБОЛЕВАНИЯ И ФАКТОРЫ РИСКА ИХ РАЗВИТИЯ У БОЛЬНЫХ ВИЧ-ИНФЕКЦИЕЙ СТАРШЕ 40 ЛЕТ

Objective: Evaluation of CVD and their risk factors in Russian 40+ HIV-infected patients is a key objective of the study. Materials and Methods: A retrospective analysis of 1872 medical records of 40+ HIV-infected patients from 12 regions of Russia on HAART was performed, including assessment of CVD presence, their risk factors and 10-years CVD risk based on SCORE. All patients received ARV treatment; the average duration of admission was 5 years (1–2 years – 43%, 3–5 years – 29%, over 5 years – 28%). Results: High incidence of CVD was observed: hypertension – 48%, including cerebrovascular disease – 2%; CAD – 9%, including myocardial infarction – 6%. Analysis of cardiovascular risk factors showed that 19% were overweight, lipid metabolism disorders were detected in 30% of patients, diabetes in 5%. 51% of patients smoked, systematic intake of alcohol in 61% of patients. 69% of patients had a risk of fatal CVD within 10 years based on SCORE, 16% of patients had a high/very high risk. Analysis of metabolic parameters showed that 99,4% of patients needed lifestyle improvement measures, 85% needed lipid lowering medication. One third of patients were constantly taking cardiovascular medications. Conclusions: CVD and metabolic disorders are more common for 40+ HIV-infected patients than for general population. ART assessment in 40+ patients additionally to viral load and CD4 level, should include analysis of cardiovascular risk factors and comorbidities. In elder patients ART regimen choice is particularly important, considering the risks of development and/or progression of CVD and risk of drugdrug interactions development.Цель: оценка сопутствующих заболеваний (ССЗ) и факторов риска их развития в российской популяции ВИЧ-инфицированных пациентов старше 40 лет. Материалы и методы: выполнен ретроспективный анализ карт 1872 ВИЧ-инфицированных пациентов старше 40 лет из 12 регионов России, включая оценку ССЗ, факторов риска их развития и 10-летний риск ССЗ по шкале SCORE. Все пациенты получали АРТ; средняя продолжительность терапии составила 5 лет (1–2 года – 43%, 3–5 лет – 29%, более 5 лет – 28%). Результаты: наблюдалась высокая частота ССЗ: артериальная гипертензия – 48%, включая нарушения мозгового кровообращения – 2%; ИБС – 9%, включая инфакрт миокарда – 6%. Анализ сердечно-сосудистых факторов риска показал ожирение у 19% пациентов, нарушения липидного обмена у 30% пациентов, сахарный диабет у 5%. Курение было отмечено у 51% пациентов, систематическое употребление алкоголя у 61%. 69% имели риск смертельного ССЗ в течение 10 лет по шкале SCORE, у 16% пациентов наблюдался высокий/очень высокий риск. Анализ нарушений метаболизма показал, что 99,4% пациентов нуждаются в различных мерах по изменению образа жизни, 85% нуждаются в гиполипидемической терапии. Одна треть пациентов постоянно получали сердечно-сосудистую терапию. Заключение: в группе больных ВИЧ-инфекцией старше 40 лет чаще выявляются заболевания сердечно-сосудистой системы, нарушение обмена веществ, по сравнению с общей популяцией. Анализ эффективности антиретровирусной терапии (АРТ) пациентов старше 40 лет дополнительно к вирусной нагрузке и уровню CD4 клеток должен включать анализ сердечно-сосудистых факторов риска и сопутствующих заболеваний. Для пациентов старшего возраста выбор режима АРТ особенно важен, учитывая риск развития и/или прогрессирования ССЗ и риск возникновения лекарственных взаимодействий

Regional features of migrants’ treatment (the case of the Tomsk and Vladimir Regions)

Цель данной статьи – сравнительный анализ отношения к этническим мигрантам в двух регионах России: Томской и Владимирской областях. Его актуальность связана с высоким миграционным притоком иностранных граждан в различные регионы Российской Федерации. По данным ООН (2015 г.), наша страна является третьей в мире по притоку мигрантов. При этом отсутствует достоверная и сопоставимая социологическая информация как об отношении к ним со стороны местного населения, так и об определяющих его факторах. На фоне тенденции роста межнациональной напряженности в отношениях с мигрантами результаты подобных исследований приобретают важное социально-политическое значение. Статья опирается на результаты репрезентативных анкетных опросов населения Томской области в 2014 г. (n?= 563) и Владимирской – в 2015 г. (n = 500) с использованием общей методики. В процессе исследования в «принимающем сообществе» были выделены группы с различным уровнем толерантности по отношению к мигрантам. В дальнейшем осуществлялось сопоставление различных групп толерантности населения в двух регионах РФ – Владимирской и Томской областях. Обнаружено, что отношение к мигрантам в регионах может различаться даже при сходных экономических условиях и в рамках однородной политической ситуации. В процессе исследования установлены значительные различия в размерах групп, демонстрирующих неодинаковые степени толерантности по отношению к мигрантам. Если в Томской области половину выборки можно отнести к группе толерантных, то во Владимирском регионе группа толерантных в процентном отношении сопоставима с группой ксенофобов. Специфична структура установок в отношении мигрантов: для Томской области более значимо различие между образовательными и трудовыми мигрантами. Полученные результаты актуализируют вопрос о факторах, дифференцирующих отношение к мигрантам в разных регионах одной страны. На основании полученных результатов выдвинута гипотеза, в соответствии с которой важное место среди этих факторов может занимать специфика локального городского социально-культурного контекста. Так, в Томске, позиционируемом как образовательный центр, имеет место больший уровень толерантности по отношению к мигрантам. Делается вывод о необходимости проведения дополнительных исследований с использованием качественных методов для проверки данной гипотезы.This article presents a comparative analysis of attitudes toward ethnic migrants in two Russian regions: the Tomsk and Vladimir Regions. Its relevance is associated with a high migration influx of foreign citizens into various Russian regions. According to the UN data (2015), our country is the third in the world in terms of the migrants’ influx. Moreover, there is no reliable and comparable sociological information both about the attitude of the local population to them and about the factors that determine it. Against the backdrop of a growing trend of interethnic tension in relations with migrants, the results of such studies acquire important social and political significance. This article relies on the results of representative questionnaires of the population of the Tomsk (in 2014, 563 respondents) and Vladimir Regions (2015, 500) using the general methodology. In the process of research, groups with different levels of tolerance towards migrants were identified in the “host community”. Subsequently, different groups of tolerance of the population were compared in these two regions. The findings show that the attitude towards migrants in the regions can vary even under similar economic conditions and within the framework of a uniform political situation. Significant differences were found in the size of groups that showed varying degrees of tolerance towards migrants. While in the Tomsk Region, the half of the sample can be attributed to the group of the tolerant people, in the Vladimir Region, their percentage is equal to the xenophobes’. The structure of attitudes towards migrants presents particular interest: for the Tomsk Region, the difference between educational and labor migrants is more significant. The obtained results actualize the issue of factors differentiating attitudes towards migrants in different regions of one country. Based on the results obtained, the authors propose a hypothesis that the specificity of the local urban social and cultural context can occupy an important place among these factors. Therefore, in Tomsk (an educational center), there is an obviously higher level of tolerance towards migrants. The authors speak for additional studies using qualitative methods to test their hypothesis

The main features of semantic structure of the commercial creolized media text

Рассмотрены особенности смысловой структуры рекламного креолизованного медиатекста: определены средства выражения главной мысли, тезисов и аналитической оценки ситуации; отмечены функции иконических компонентов в структуре сообщения, а также роль объективных и субъективных факторов в восприятии поликодового текста. Выделены типы смысловой структуры креолизованной рекламы: смысловая структура дискурса адресанта и смысловая структура дискурса адресата. Предложены варианты их анализа: интенциональный, интерпретативный, интегральный. Отмечены некоторые факторы, влияющие на эффективность креолизованного рекламного сообщения.The main features of the semantic structure of the creolized media texts are being examined: the means of main idea’s expression as well as the theses and analytical evaluation of the situation are being defined; the functions of iconical components in the communication structure are being marked, as well as the role of the objective and subjective factors of the poly-code text perception. The types of the semantic structure of the creolized commercial are being defined: the semantic structure of the sender’s discourse and the semantic structure of the recepient’s discourse. Several was of its analysis are being offered: intentional, integral and interpretative. Some factors that influence the effectiveness of the creolized advertisement are being mentioned