2,543 research outputs found

    How Far Is Too Far: Analyzing the Collateral Law Applicable in State Court Section 1983 Litigation

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    ‘Single’ v. ‘panel’ appointed forensic mental observations: Is the referral process ethically justifiable?

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    Objective. To compare the outcome and psychiatric morbidity of the forensic mental observation referrals, in the two legally created groups of detainees awaiting trial – the ‘singles’, representing the minor violent and non-violent offenders evaluated by a single-state appointed psychiatrist, v. the ‘panels’, representing the seriously violent offenders evaluated by two or more psychiatrists.Methods. A retrospective record review covered 200 cases, comprising all individuals admitted to the forensic unit of Sterkfontein Hospital for 30 days psychiatric observation from January to August 2010. Pearson’s χ2 test for categorical data were used to determine statistical significance. Results. Of 110 singles, 49 (44.55%) were found fit for trial and 40 (40.4%) were found criminally responsible. Of the 90 ‘panel’ cases 60 (66.67%) were found fit for trial and 57 (64.77%) were found criminally responsible (p=0.002 and p=0.001, respectively) Conclusion. Those charged with seriously violent offences appear more likely to be found both fit and responsible, compared with those charged with less serious offences

    Case report: Basedow paraplegia: A possible misnomer

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    Thyrotoxic myopathy frequently occurs in clinical practice; however, the association of hyperthyroidism with a flaccid, areflexic paraplegia, so-called Basedow paraplegia, appears to represent a controversial and doubtful entity. An 18-year-old female with undiagnosed and untreated Graves’ disease presented with acute onset of global weakness predominantly in the lower limbs, but also affecting the upper limbs. The weakness was accompanied by hypotonia and areflexia. Clinically, the patient had a goitre and signs of thyroid ocular disease. Laboratory testing confirmed the presence of hyperthyroidism, and thyroid-stimulating hormone receptor antibodies were positive. The cerebrospinal fluid protein level was raised. The electroneuronographic and needle examinations were compatible with a clear denervation process, such as acute motor axonal neuropathy, a variant of Guillain-Barré syndrome. Intravenous immunoglobulin therapy, carbimazole and propranolol were administered. The occurrence of hyperthyroidism with a flaccid, areflexic paraplegia appears to represent more of a fortuitous than a causative association. It is important to consider and treat other causes, such as acute idiopathic polyneuritis

    Comparison of HTLV-associated myelopathy (HAM) in HIV-positive and HIV-negative patients at a tertiary South African hospital

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    Background. HTLV-1 associated myelopathy (HAM), or tropical spastic paraparesis, is caused by a retrovirus, the human T-cell lymphotropic virus (HTLV). Although patients with HAM and HIV infection have been described, to our knowledge no direct comparison has been made between patients who are HIV positive and suffering from HAM (HHAM) v. those who are HIV negative and suffering from HAM.Aim. We aimed to compare clinical and radiological findings in HIV-positive and -negative patients with HAM.Methods. Adult patients who presented to the Neurology Unit at the Steve Biko Academic Hospital from May 2005 to June 2012 with a progressive myelopathy and HTLV seropositivity were retrospectively identified and their clinical and radiological data were collected and reviewed.Results. 21 patients with HAM were identified, of whom 9 were HIV-positive and 11 HIV-negative. One patient, whose HIV status had not been established, was not included in the study. Although the trend did not reach statistical significance, co-infected patients tended to present at an earlier age (HHAM 6/9 (66%) <40 years old; HAM 2/11 (18%) <40 years old) and presented to hospital earlier (HHAM 6/9 (66%) < 3 years symptomatic; HAM 7/11 (63%) > 3 years symptomatic). Cord atrophy occurred in 7/8 dually infected patients and 8/10 HIV-negative patients.Conclusion. Although the study is limited by the small number of patients, co-infected patients tended to have a younger age of onset and to present to hospital sooner, and thoracic cord atrophy was very common

    AKARI near-infrared spectroscopy of the aromatic and aliphatic hydrocarbon emission features in the galactic superwind of M 82

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    Aims. We investigate the properties of hydrocarbon grains in the galactic superwind of M 82. Methods. With AKARI, we performed near-infrared (2.5 - 4.5 um) spectroscopic observations of 34 regions in M 82 including its northern and southern halos. Results. Many of the spectra show strong emission at 3.3 um due to polycyclic aromatic hydrocarbons (PAHs) and relatively weak features at 3.4 - 3.6 um due to aliphatic hydrocarbons. In particular, we clearly detect the PAH 3.3 um emission and the 3.4 - 3.6 um features in halo regions, which are located at a distance of 2 kpc away from the galactic center. We find that the ratios of the 3.4 - 3.6 um features to the 3.3 um feature intensity significantly increase with distance from the galactic center, while the ratios of the 3.3 um feature to the AKARI 7 um band intensity do not. Conclusions. Our results clearly confirm the presence of small PAHs even in a harsh environment of the halo of M 82. The results also reveal that the aliphatic hydrocarbons emitting the 3.4 - 3.6 um features are unusually abundant in the halo, suggesting that small carbonaceous grains are produced by shattering of larger grains in the galactic superwind.Comment: 5 pages, 3 figures, 1 table, accepted for publication in A&
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