Prose of Russian Emigration Writers (V. A. Nikiforov-Volgin, I. A. Bunin, B. K. Zaitsev) in Context of Ivan Ilyin’s Religious-Philosophical Thought

The authors of this article aim to contextualize the religious-philosophical ideas of the prominent philosopher of Russian emigration, Ivan Ilyin, with the prose of Ivan Bunin, Boris Zaitsev, and Vladimir Nikiforov-Volgin. The novelty of the research lies in identifying the typological correlation between Ilyin’s ideas about the essential characteristics of national character, manifested in the pursuit of perfection, and the artistic worldview of Russian writers who interpreted life in Russia during periods of social upheaval. The introduction of the insufficiently studied phenomenon of Vladimir Nikiforov-Volgin’s creative work into the field of prose by well-known authors is also an aspect of the novelty of this work. The analysis confirms that the writers perceptively revealed, through various life circumstances, often critical, the ability of people, regardless of their social status or age, to exhibit traits of Christian mercy and selflessness. Equally significant is the ability of individuals to live with a sense of light from Christian faith, despite external circumstances, and to transmit this feeling to others. Actions based on “virtues of the heart and conscience” — these most valuable principles of life according to Ilyin’s thought — are multifacetedly reflected on the pages of the works presented here

RECOMMENDATIONS FOR INTERVIEWERS CONDUCTING SOCIOLOGICAL SURVEYS: THE USE OF THE PSYCHOTYPES THEORY AND ANALYSIS OF RESPONDENTS’ NONVERBAL REACTIONS

The quality of sociological data is the problem that cannot lose relevance in the works of methodologists and practicing sociologists for decades. Procedures and techniques for the improvement of the quality of information for all type of survey methods are developing. The purpose of the article is to inform the interviewers conducting semi-structured or unstructured interviews of the recommendations developed on the basis of the theory of psychotypes (by V.V. Ponomarenko). This technology will allow to improve the quality of sociological data. Identification of the psychotype of the respondent and his emotional reactions to different sensitive topics during the interview are the basis of this technology. Emotional reactions can be traced by nonverbal cues (facial expressions, gestures and poses) and interpreted by the technology of the analysis of nonverbal reactions developed and approved earlier. During the multi-stage experiment, the reactions significant in the course of interview were traced and analyzed - irritation, surprise, sadness, contempt, joy, fear, disgust, stress/discomfort, doubt/indecision, manifestations of mental processes. At the first phase, representatives of ‘ideal types’ of each psychotype were selected by an abridged psychological test and external diagnostics based on sensitive topics. As a result, the recommendations for a semi-structured interview were formulated. To use this technique, it is necessary to test an interviewee before the interview by the abridged psychological technique (in case there are doubts after the visual diagnostics). According to the psychotype the interviewer pays attention to the sensitive topics of the in-terview, and during the interview can reformulate the open-ended questions to reduce the sensitivity of significant topics for each respondent

SiC Nanofibers in Canals and Pores of Cordierite Honeycomb Material as a Support for Catalyst in CO-PROX Reaction

The Cu–Co oxide system supported on SiC nanofibers deposited on cordierite was studied in the CO oxidation reaction in the presence of hydrogen

ANALYSIS OF THE FACTORS INFLUENCING THE PROCESSES OF VERTICAL MIGRATION OF 137Cs AND 90Sr IN SOILS

It was found that the radionuclides falling on the surface of the soil moving deeper into the soil eventually. In this paper factors that affect vertical migration processes 137Cs and 90Sr are identified according to normative methods, and also the behavior of radionuclides in soils in dynamic and static conditions are studied

Effect of antibodies to glutamate on age-related memory changes in C57Bl/6 mice

Chronic intranasal administration of antibodies to glutamate to aging C57Bl/6 mice improved passive avoidance conditioning, had no effect on horizontal and vertical locomotor activity, but slowed locomotion in the open-field test. Administration of antibodies to glutamate increased the content of dopamine and its metabolites in mouse hippocampus, but had no effect on the metabolism of neurotransmitter amino acids. In the frontal cortex, antibodies to glutamate did not affect neurotransmitter metabolism, but increased the level of both excitatory and inhibitory amino acids without changing their ratio

Increased Persistence of Initial Treatment for HIV Infection with Modern Antiretroviral Therapy

Background: Initiating antiretroviral therapy (ART) early improves clinical outcomes and prevents transmission. Guidelines for first-line therapy have changed with the availability of newer ART agents. In this study, we compared persistence and virologic responses with initial ART according to the class of anchor agent used. Setting: An observational clinical cohort study in the Southeastern United States. Methods: All HIV-infected patients participating in the UNC Center for AIDS Research Clinical Cohort (UCHCC) and initiating ART between 1996 and 2014 were included. Separate time-to-event analyses with regimen discontinuation and virologic failure as outcomes were used, including Kaplan-Meier survival curves and adjusted Cox proportional hazards models. Results: One thousand six hundred twenty-four patients were included (median age of 37 years at baseline, 28% women, 60% African American, and 28% white). Eleven percent initiated integrase strand transfer inhibitor (INSTI), 33% non-nucleoside reverse transcriptase inhibitor (NNRTI), 20% boosted protease inhibitor, 27% other, and 9% NRTI only regimens. Compared with NNRTI-containing regimens, INSTI-containing regimens had an adjusted hazard ratio of 0.49 (95% confidence interval, 0.35 to 0.69) for discontinuation and 0.70 (95% confidence interval, 0.46 to 1.06) for virologic failure. All other regimen types were associated with increased rates of discontinuation and failure compared with NNRTI. Conclusions: Initiating ART with an INSTI-containing regimen was associated with lower rates of regimen discontinuation and virologic failure

Jean Pecquet (1622–1674). To the 400th anniversary of the birth

The article is dedicated to the 400th anniversary of the birth of the outstanding French anatomist, physician and philosopher Jean Pecquet (1622–1674). Pecquet’s biography is connected with the city of Dieppe, where the future scientist was born and got his primary education, and with Paris, where he made his main discoveries in anatomy. Throughout his life, Pecquet collaborated with many prominent scientists of that time (Jacques Mentel, Louis Gayant, Jean Riolan (the Younger)), including not only physicians and anatomists, but also physicists such as Blaise Pascal, Edme Mariotte, Marin Mersenne and Evangelista Torricelli. Pecquet’s most famous discovery is the chyle cictern, or cisterna chyli. The structure was named after of the scientist – “Pecquet’s reservoir (cistern)”. But more revolutionary discovery made by Pecquet is revealing and proving the fact that the lymphatic ducts flow into the superior vena cava indirectly through the venous angles and refuting the conventional opinion on the drainage of lymph into the liver. An important help in Pecquet’s anatomical research and experiments was his passion for the physical and mathematical sciences. In collaboration with Edme Marriott, Pecquet studied the structure of the eyeball and turned out to be more foresighted, because, unlike Marriott, he correctly understood the role of the retina in the functioning of the eye as an organ of vision. Pecquet was one of William Harvey’s supporters regarding his concept of blood circulation. He introduced cutting-edge at that moment technologies into the anatomy methodology, including animal experiments in vivo, and made a fateful contribution to the progress of anatomical science

Інформаційна технологія організації моніторингу впливу мотивованого вибору спеціальності студентом на успішність навчання в ЗВО

Рассмотрена актуальная проблема организации информационной технологии для проведения исследования для влияния мотивированного выбора специальности студентом на успеваемость при обучении в УВО. Для проведения анкетирования разработано мобильное приложение, созданное на языке программирования Java в интегрированной среде разработки Android Studio. Полученные результаты анализировались с помощью SPSS – программы для статистической обработки данных. По результатам исследования сделаны перспективные выводы.The article explores the actual problem of organization of the information technology for conducting research of the social and psychological climate in the groups of students. Two questionnaires were created for students' questionnaires. The first survey was conducted according to the classical Hans Eysenck methodology for the determination of the temperament (this technique is one of the most popular in modern psychology). The goal was to study the personality of each of the students from several components: extraversion and psychotype, emotional-volitional stability and the classification of the temperament in correspondence with the classical types. The second questionnaire was sociological and was created with the goal to clarify the degree of the motivation level in terms of the choice of the study program, the level of satisfaction with the educational process, substantiation of personal opinion about methods of teaching at the university, and a need of potential changes of the teaching strategies. The survey was conducted among the students of the ten study programs at the Oles Honchar Dnipro National University: "Political Science", "Sociology", "Informatics", "Applied Mathematics", "Software Engineering"; "System analysis"; "Special Education", "Psychology"; "Chemistry", "Social Work". The total number of survey participants included 205 students. In order to optimize the process of collection of the information a mobile questionnaires application was created. This application was created using the Java programming language in the integrated Android Studio mobile application environment. When creating the application, a convenient user interface of the application was developed with an adaptive design, convenient menu, good running functionality, and the ability to select a passing text. View hierarchies and their subclasses were also used. View objects are the widgets of users interface, such as buttons or text fields. The collected information was analized with the help of SPSS and the results were  used  to provide objective summaries. In the future it is planned to add such functions as the option to search for a survey by the survey title; sending the result via email, SMS or via social networks; to view statistics on various surveys at the same time; to increase the number of surveys as well as to optimize the application design.Розглянуто актуальну проблему організації інформаційної технології для проведення дослідження впливу мотивованого вибору спеціальності студентом на успішність навчання в ЗВО. Для проведення анкетувань розроблено мобільний застосунок, який було створено за допомогою мови програмування Java в інтегрованому середовищі розробки Android Studio. Отримані відповіді аналізувалися за допомогою SPSS – програми для статистичної обробки даних. За результатами дослідження зроблено перспективні висновки

New Insights on Rift Basin Development and the Geological Carbon Cycle, Mass Extinction, and Carbon Sequestration...

Field trip guide to northern Newark basin of New York and New Jersey including information on stratigraphic and tectonic framework based on outcrops, cores, drill holes and seismic lines

New antiretroviral agent use affects prevalence of HIV drug resistance in clinical care populations

OBJECTIVE: To estimate the prevalence of HIV drug resistance over time and identify risk factors for multiclass resistance. DESIGN: Prospective clinical cohort of HIV-infected patients at the University of North Carolina. METHODS: Among antiretroviral therapy (ART)-experienced patients in care 2000-2016, we estimated annual prevalences of cumulative resistance, defined as at least one major mutation by drug class. Clinical data and multiple imputation were used when genotypic data were missing, and mutations were carried forward in time. We estimated resistance odds ratios comparing characteristics of patients in care in 2016. RESULTS: A total of 3682 patients contributed 23 169 person-years. Prevalence of at least one major resistance mutation, irrespective of viral suppression, peaked in 2005 with 49% (95% confidence interval 46, 52) and decreased to 38% (35, 40) in 2016. Resistance to nucleoside reverse transcriptase inhibitors, protease inhibitors, and nonnucleoside reverse transcriptase inhibitors also peaked in 2005-2007 and decreased to 28 (26, 31), 14 (12, 16), and 27% (24, 29) in 2016, respectively. In 2016, prevalence of integrase strand transfer inhibitor (INSTI) resistance was 2% (1, 3) and triple-class resistance 10% (9, 12). Over the study period, cumulative resistance was frequent among patients with detectable viremia, but uncommon among patients initiating ART post-2007. Among 1553 patients in care in 2016, ART initiation at an older age, with an INSTI, and with higher CD4 cell counts were associated with resistance to fewer or no classes. CONCLUSION: Prevalence of resistance to older ART classes has decreased in the last 10 years in this clinical cohort, whereas INSTI resistance has increased but remained very low. Patients with viremia continue to have a high burden of resistance even if they initiated ART recently